Quantitative description of the asymmetry in magnetization transfer effects around the water resonance in the human brain

Magnetic Resonance in Medicine

Volumn 58, Issue 4, 2007, Pages 786-793

  Hua, Jun ^a,b   Jones, Craig K ^a,b   Blakeley, Jaishri ^a   Smith, Seth A ^a,b   Van Zijl, Peter C M ^a,b   Zhou, Jinyuan ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

Amide proton transfer; Asymmetry; CEST; Human brain; Magnetization transfer; MT; z spectrum

Indexed keywords

AMIDES; BRAIN; FREQUENCY ALLOCATION; IRRADIATION; TISSUE;

AMIDE PROTON TRANSFERS; ASYMMETRY; CEST; HUMAN BRAIN; MAGNETIZATION TRANSFER; Z-SPECTRUM;

MAGNETIZATION;

AMIDE; WATER;

ARTICLE; BRAIN; HUMAN; IMAGING SYSTEM; IRRADIATION; MAGNETIC FIELD; NEUROIMAGING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTON TRANSPORT; RADIOFREQUENCY; WHITE MATTER;

EID: 35048879622     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21387     Document Type: Article

References (35)

1. Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1989;10:135-144.
2. Balaban RS, Ceckler TL. Magnetization transfer contrast in magnetic resonance imaging. Magn Reson Q 1992;8:116-137.
3. Bryant RG. The dynamics of water-protein interactions. Annu Rev Biophys Biomol Struct 1996;25:29-53.
4. Henkelman RM, Stanisz GJ, Graham SJ. Magnetization transfer in MRI: a review. NMR Biomed 2001;14:57-64.
5. Sled JG, Pike GB. Quantitative interpretation of magnetization transfer in spoiled gradient echo MRI sequences. J Magn Reson 2000;145:24-36.
6. Tozer D, Ramani A, Barker GJ, Davies GR, Miller DH, Tofts PS. Quantitative magnetization transfer mapping of bound protons in multiple sclerosis. Magn Reson Med 2003;50:83-91.
7. Stanisz GJ, Odrobina EE, Pun J, Escaravage M, Graham SJ, Bronskill MJ, Henkelman RM. T-1, T-2 relaxation and magnetization transfer in tissue at 3T. Magn Reson Med 2005;54:507-512.
8. Pekar J, Jezzard P, Roberts DA, Detre JA, Leigh JS, Frank JA, McLaughlin AC. Perfusion imaging with MTC offset compensation. In: Proceedings of the 2nd Annual Meeting of SMR, San Francisco, CA, 1994. p 281.
9. Stein AD, Roberts DA, McGowan J, Reddy R, Leigh JS. Asymmetric cancellation of magnetization transfer effects. In: Proceedings of the 2nd Annual Meeting of SMR, San Francisco, CA, 1994. p 880.
10. Pekar J, Jezzard P, Roberts DA, Leigh JS, Frank JA, McLaughlin AC. Perfusion imaging with compensation for asymmetric magnetization transfer effects. Magn Reson Med 1996;35:70-79.
11. Swanson SD, Pang Y. MT is symmetric but shifted with respect to water. In: Proceedings of the 11th Annual Meeting of ISMRM, Toronto, Ontario, Canada, 2003 (Abstract 660).
12. Zhou J, Payen J, Wilson DA, Traystman RJ, van Zijl PCM. Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nature Med 2003;9:1085-1090.
13. Detre JA, Leigh JS, Williams DS, Koretsky AP. Perfusion imaging. Magn Reson Med 1992;23:37-45.
14. Williams DS, Detre JA, Leigh JS, Koretsky AP. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci USA 1992;89:212-216.
15. Detre JA, Zhang W, Roberts DA, Silva AC, Williams DS, Grandis DJ, Koretsky AP, Leigh JS. Tissue specific perfusion imaging using arterial spin labeling. NMR Biomed 1994;10:135-144.
16. Zhou J, Lal B, Wilson DA, Laterra J, van Zijl PCM. Amide proton transfer (APT) contrast for imaging of brain tumors. Magn Reson Med 2003;50:1120-1126.
17. Jones CK, Schlosser MJ, van Zijl PC, Pomper MG, Golay X, Zhou J. Amide proton transfer imaging of human brain tumors at 3T. Magn Reson Med 2006:585-592.
18. Zhou J, van Zijl PC. Chemical exchange saturation transfer imaging and spectroscopy. Progr NMR Spectr 2006;48:109-136.
19. Henkelman RM, Huang X, Xiang Q-S, Stanisz GJ, Swanson SD, Bronskill MJ. Quantitative interpretation of magnetization transfer. Magn Reson Med 1993;29:759-766.
20. Morrison C, Henkelman RM. A model for magnetization transfer in tissues. Magn Reson Med 1995;33:475-482.
21. Morrison C, Stanisz G, Henkelman RM. Modeling magnetization transfer for biological-like systems using a semi-solid pool with a super-Lorentzian lineshape and dipolar reservoir. J Magn Reson B 1995;108:103-113.
22. Quesson B, Thiaudiere E, Delalande C, Dousset V, Chateil JF, Canioni P. Magnetization transfer imaging in vivo of the rat brain at 4.7 T: interpretation using a binary spin-bath model with a superLorentzian lineshape. Magn Reson Med 1997;38:974-980.
23. Ramani A, Dalton C, Miller DH, Tofts PS, Barker GJ. Precise estimate of fundamental in-vivo MT parameters in human brain in clinically feasible times. Magn Reson Imaging 2002;20:721-731.
24. Smith SA, Farrell JA, Jones CK, Reich DS, Calabresi PA, van Zijl PC. Pulsed magnetization transfer imaging with body coil transmission at 3 Tesla: feasibility and application. Magn Reson Med 2006;56:866-875.
25. Chai JW, Chen C, Chen JH, Lee SK, Yeung HN. Estimation of in vivo proton intrinsic and cross-relaxation rate in human brain. Magn Reson Med 1996;36:147-152.
26. Sled JG, Pike GB. Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn Reson Med 2001;46:923-931.
27. de Graaf RA, van Kranenburg A, Nicolay K. Off-resonance metabolite magnetization transfer measurements on rat brain in situ. Magn Reson Med 1999;41:1136-1144.
28. van Zijl PCM, Zhou J, Mori N, Payen J, Mori S. Mechanism of magnetization transfer during on-resonance water saturation, a new approach to detect mobile proteins, peptides, and lipids. Magn Reson Med 2003;49:440-449.
29. Chen JH, Sambol EB, DeCarolis P, O'Connor R, Geha RC, Wu YV, Singer S. High-resolution MAS NMR spectroscopy detection of the spin magnetization exchange by cross-relaxation and chemical exchange in intact cell lines and human tissue specimens. Magn Reson Med 2006;55:1246-1256.
30. Wolff SD, Balaban RS. NMR imaging of labile proton exchange. J Magn Reson 1990;86:164-169.
31. Guivel-Scharen V, Sinnwell T, Wolff SD, Balaban RS. Detection of proton chemical exchange between metabolites and water in biological tissues. J Magn Reson 1998;133:36-45.
32. Ward KM, Aletras AH, Balaban RS. A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST). J Magn Reson 2000;143:79-87.
33. Zhang S, Winter P, Wu K, Sherry AD. A novel europium(III)-based MRI contrast agent. J Am Chem Soc 2001;123:1517-1578.
34. Aime S, Barge A, Delli Castelli D, Fedeli F, Mortillaro A, Nielsen FU, Terreno E. Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications. Magn Reson Med 2002;47:639-648.
35. Hua J, van Zijl P, Sun P, Zhou J. Quantitative description of magnetization transfer (MT) asymmetry in experimental brain tumors. In: Proceedings of the 15th Annual Meeting of ISMRM, Berlin, Germany, 2007 (Abstract 882).