Magnetic resonance chemical exchange saturation transfer imaging and nanotechnology

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Volumn 4, Issue 4, 2012, Pages 389-398

  Winter, Patrick M ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOUND WATERS; BULK WATER; CHEMICAL EXCHANGE SATURATION TRANSFER; EXCHANGEABLE PROTONS; IMAGE CONTRASTS; IN-VIVO; LIMIT OF DETECTION; NANOPARTICLE SYSTEMS; PARACEST; PARAMAGNETIC CHELATES; PERFLUOROCARBONS; PREPULSES; PULSE SEQUENCE;

DENDRIMERS; FUNCTIONAL POLYMERS; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MEDICAL APPLICATIONS; NANOPARTICLES; PARAMAGNETISM; PROTONS;

CHEMICAL DETECTION;

CHELATE; CHEMICAL EXCHANGE SATURATION TRANSFER AGENT; DENDRIMER; DIAMAGNETIC LIPOSOME; FLUOROCARBON; LIPOSOME; NANOPARTICLE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PARAMAGNETIC CHEMICAL EXCHANGE SATURATION TRANSFER AGENT; POLYMER; PROTON; UNCLASSIFIED DRUG;

ADENOVIRUS; CHEMICAL EXCHANGE SATURATION TRANSFER NUCLEAR MAGNETIC RESONANCE IMAGING; DRUG MONITORING; DRUG RELEASE; LIMIT OF DETECTION; NANOIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTON TRANSPORT; REVIEW;

ANIMALS; COMPUTER SIMULATION; CONTRAST MEDIA; HUMANS; MAGNETIC RESONANCE IMAGING; MOLECULAR IMAGING; NANOTECHNOLOGY;

EID: 84862684774     PISSN: 19395116     EISSN: 19390041     Source Type: Journal    
DOI: 10.1002/wnan.1167     Document Type: Review

References (45)

1. Ward KM, Aletras AH, Balaban RSA new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST)J Magn Reson 2000, 143:79-87
2. Zhou J, Wilson DA, Sun PZ, Klaus JA, Van Zijl PCQuantitative description of proton exchange processes between water and endogenous and exogenous agents for WEX, CEST, and APT experimentsMagn Reson Med 2004, 51:945-952
3. Zhang S, Winter P, Wu K, Sherry ADA novel europium(III)-based MRI contrast agentJ Am Chem Soc 2001, 123:1517-1518
4. Hancu I, Dixon WT, Woods M, Vinogradov E, Sherry AD, Lenkinski RECEST and PARACEST MR contrast agentsActa Radiol 2010, 51:910-923
5. Woods M, Woessner DE, Sherry ADParamagnetic lanthanide complexes as PARACEST agents for medical imagingChem Soc Rev 2006, 35:500-511
6. Cai K, Kiefer GE, Caruthers SD, Wickline SA, Lanza GM, Winter PMQuantification of water exchange kinetics for targeted PARACEST perfluorocarbon nanoparticlesNMR Biomed 2011, 25: 279-285
7. Fisher JP, Dean D, Mikos AGPhotocrosslinking characteristics and mechanical properties of diethyl fumarate/poly(propylene fumarate) biomaterialsBiomaterials 2002, 23:4333-4343
8. Vasalatiy O, Gerard RD, Zhao P, Sun X, Sherry ADLabeling of adenovirus particles with PARACEST agentsBioconjug Chem 2008, 19:598-606
9. Vinogradov E, Zhang S, Lubag A, Balschi JA, Sherry AD, Lenkinski REOn-resonance low B1 pulses for imaging of the effects of PARACEST agentsJ Magn Reson 2005, 176:54-63
10. Li AX, Suchy M, Li C, Gati JS, Meakin S, Hudson RH, Menon RS, Bartha RIn vivo detection of MRI-PARACEST agents in mouse brain tumors at 9.4 TMagn Reson Med 2011, 66:67-72
11. Liu G, Ali MM, Yoo B, Griswold MA, Tkach JA, Pagel MDPARACEST MRI with improved temporal resolutionMagn Reson Med 2009, 61:399-408
12. Sheth VR, Li Y, Chen LQ, Howison CM, Flask CA, Pagel MDMeasuring in vivo tumor pHe with CEST-FISP MRIMagn Reson Med 2011, 67:760-768
13. Aime S, Delli Castelli D, Terreno EHighly sensitive MRI chemical exchange saturation transfer agents using liposomesAngew Chem Int Ed Engl 2005, 44:5513-5515
14. Aime S, Delli Castelli D, Lawson D, Terreno EGd-loaded liposomes as T1, susceptibility, and CEST agents, all in oneJ Am Chem Soc 2007, 129: 2430-2431
15. Terreno E, Cabella C, Carrera C, Delli Castelli D, Mazzon R, Rollet S, Stancanello J, Visigalli M, Aime SFrom spherical to osmotically shrunken paramagnetic liposomes: an improved generation of LIPOCEST MRI agents with highly shifted water protonsAngew Chem Int Ed Engl 2007, 46:966-968
16. Delli Castelli D, Terreno E, Carrera C, Giovenzana GB, Mazzon R, Rollet S, Visigalli M, Aime SLanthanide-loaded paramagnetic liposomes as switchable magnetically oriented nanovesiclesInorg Chem 2008, 47:2928-2930
17. Terreno E, Barge A, Beltrami L, Cravotto G, Castelli DD, Fedeli F, Jebasingh B, Aime SHighly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagentsChem Commun (Camb) 2008, 5:600-602
18. Liu G, Moake M, Har-el Y-E, Long CM, Chan KW, Cardona A, Jamil M, Walczak P, Gilad AA, Sgouros G, et alIn vivo multicolor molecular MR imaging using diamagnetic chemical exchange saturation transfer liposomesMagn Reson Med 2012doi:10.1002/mrm.23100
19. Snoussi K, Bulte JW, Gueron M, van Zijl PCSensitive CEST agents based on nucleic acid imino proton exchange: detection of poly(rU) and of a dendrimer-poly(rU) model for nucleic acid delivery and pharmacologyMagn Reson Med 2003, 49:998-1005
20. Choi J, Kim K, Kim T, Liu G, Bar-Shir A, Hyeon T, McMahon MT, Bulte JW, Fisher JP, Gilad AAMultimodal imaging of sustained drug release from 3-D poly(propylene fumarate) (PPF) scaffoldsJ Control Release 2011, 156:239-245
21. Langereis S, Keupp J, van Velthoven JL, de Roos IH, Burdinski D, Pikkemaat JA, Grull HA temperature-sensitive liposomal 1H CEST and 19F contrast agent for MR image-guided drug deliveryJ Am Chem Soc 2009, 131:1380-1381
22. Ali MM, Yoo B, Pagel MDTracking the relative in vivo pharmacokinetics of nanoparticles with PARACEST MRIMol Pharm 2009, 6:1409-1416
23. Winter PM, Cai K, Chen J, Adair CR, Kiefer GE, Athey PS, Gaffney PJ, Buff CE, Robertson JD, Caruthers SD, et alTargeted PARACEST nanoparticle contrast agent for the detection of fibrinMagn Reson Med 2006, 56:1384-1388
24. Liu G, Li Y, Sheth VR, Pagel MDImaging In vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agentMol Imaging 2011doi:10.2310/7290.2011.00026
25. Li Y, Sheth VR, Liu G, Pagel MDA self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activityContrast Media Mol Imaging 2011, 6:219-228
26. Liu G, Li Y, Pagel MDDesign and characterization of a new irreversible responsive PARACEST MRI contrast agent that detects nitric oxideMagn Reson Med 2007, 58:1249-1256
27. Yoo B, Pagel MDA PARACEST MRI contrast agent to detect enzyme activityJ Am Chem Soc 2006, 128:14032-14033
28. Pikkemaat JA, Wegh RT, Lamerichs R, van de Molengraaf RA, Langereis S, Burdinski D, Raymond AY, Janssen HM, de Waal BF, Willard NP, et alDendritic PARACEST contrast agents for magnetic resonance imagingContrast Media Mol Imaging 2007, 2:229-239
29. Winter PM, Cai K, Caruthers SD, Wickline SA, Lanza GMEmerging nanomedicine opportunities with perfluorocarbon nanoparticlesExpert Rev Med Devices 2007, 4:137-145
30. Winter PM, Caruthers SD, Allen JS, Cai K, Williams TA, Lanza GM, Wickline SAMolecular imaging of angiogenic therapy in peripheral vascular disease with ανβ3-integrin-targeted nanoparticlesMagn Reson Med 2010, 64:369-376
31. Winter PM, Caruthers SD, Kassner A, Harris TD, Chinen LK, Allen JS, Lacy EK, Zhang H, Robertson JD, Wickline SA, et alMolecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel α(ν)β3-targeted nanoparticle and 1.5 tesla magnetic resonance imagingCancer Res 2003, 63:5838-5843
32. Winter PM, Caruthers SD, Zhang H, Williams TA, Wickline SA, Lanza GMAntiangiogenic synergism of integrin-targeted fumagillin nanoparticles and atorvastatin in atherosclerosisJACC Cardiovasc Imaging 2008, 1:624-634
33. Winter PM, Morawski AM, Caruthers SD, Fuhrhop RW, Zhang H, Williams TA, Allen JS, Lacy EK, Robertson JD, Lanza GM, et alMolecular imaging of angiogenesis in early-stage atherosclerosis with α(ν)β3-integrin-targeted nanoparticlesCirculation 2003, 108:2270-2274
34. Winter PM, Neubauer AM, Caruthers SD, Harris TD, Robertson JD, Williams TA, Schmieder AH, Hu G, Allen JS, Lacy EK, et alEndothelial α(ν)β3 integrin-targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosisArterioscler Thromb Vasc Biol 2006, 26:2103-2109
35. Winter PM, Schmieder AH, Caruthers SD, Keene JL, Zhang H, Wickline SA, Lanza GMMinute dosages of α(ν)β3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbitsFASEB J 2008, 22:2758-2767
36. Flacke S, Fischer S, Scott MJ, Fuhrhop RJ, Allen JS, McLean M, Winter P, Sicard GA, Gaffney PJ, Wickline SA, et alNovel MRI contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaquesCirculation 2001, 104:1280-1285
37. Winter PM, Caruthers SD, Yu X, Song SK, Chen J, Miller B, Bulte JW, Robertson JD, Gaffney PJ, Wickline SA, et alImproved molecular imaging contrast agent for detection of human thrombusMagn Reson Med 2003, 50:411-416
38. Morawski AM, Winter PM, Yu X, Fuhrhop RW, Scott MJ, Hockett F, Robertson JD, Gaffney PJ, Lanza GM, Wickline SAQuantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticlesMagn Reson Med 2004, 52:1255-1262
39. Neubauer AM, Myerson J, Caruthers SD, Hockett FD, Winter PM, Chen J, Gaffney PJ, Robertson JD, Lanza GM, Wickline SAGadolinium-modulated 19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imagingMagn Reson Med 2008, 60:1066-1072
40. Aime S, Barge A, Delli Castelli D, Fedeli F, Mortillaro A, Nielsen FU, Terreno EParamagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applicationsMagn Reson Med 2002, 47:639-648
41. Terreno E, Castelli DD, Cravotto G, Milone L, Aime SLn(III)-DOTAMGly complexes: a versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applicationsInvest Radiol 2004, 39:235-243
42. Zhang S, Malloy CR, Sherry ADMRI thermometry based on PARACEST agentsJ Am Chem Soc 2005, 127:17572-17573
43. Aime S, Delli Castelli D, Fedeli F, Terreno EA paramagnetic MRI-CEST agent responsive to lactate concentrationJ Am Chem Soc 2002, 124:9364-9365
44. Trokowski R, Zhang S, Sherry ADCyclen-based phenylboronate ligands and their Eu3+ complexes for sensing glucose by MRIBioconjug Chem 2004, 15:1431-1440
45. Trokowski R, Ren J, Kalman FK, Sherry ADSelective sensing of zinc ions with a PARACEST contrast agentAngew Chem Int Ed Engl 2005, 44:6920-6923