메뉴 건너뛰기




Volumn 9, Issue 2, 2014, Pages

Recombinant human parathyroid hormone related protein 1-34 and 1-84 and their roles in osteoporosis treatment

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; PARATHYROID HORMONE RELATED PROTEIN; RECOMBINANT HUMAN PARATHYROID HORMONE RELATED PROTEIN 1-34; RECOMBINANT HUMAN PARATHYROID HORMONE RELATED PROTEIN 1-84; UNCLASSIFIED DRUG; CARRIER PROTEIN; PARATHYROID HORMONE-RELATED PROTEIN (1-34); PARATHYROID HORMONE-RELATED PROTEIN (1-84); PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

EID: 84895519024     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088237     Document Type: Article
Times cited : (20)

References (46)
  • 1
    • 84875860482 scopus 로고    scopus 로고
    • Osteoporosis: Genetic determinants and relationship with cardiovascular disease
    • Sobieszczanska M, Jonkisz J, Tabin M, Laszki-Szczachor K (2013) Osteoporosis: genetic determinants and relationship with cardiovascular disease. Adv Clin Exp Med 22: 119-124.
    • (2013) Adv Clin Exp Med , vol.22 , pp. 119-124
    • Sobieszczanska, M.1    Jonkisz, J.2    Tabin, M.3    Laszki-Szczachor, K.4
  • 2
    • 33845983304 scopus 로고    scopus 로고
    • The use of parathyroid hormone in the treatment of osteoporosis
    • DOI 10.1007/s11154-006-9007-z, Special Issue on Osteoporosis
    • Girotra M, Rubin MR, Bilezikian JP (2006) The use of parathyroid hormone in the treatment of osteoporosis. Rev Endocr Metab Disord 7: 113-121. (Pubitemid 46049523)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.1-2 , pp. 113-121
    • Girotra, M.1    Rubin, M.R.2    Bilezikian, J.P.3
  • 4
    • 84856783815 scopus 로고    scopus 로고
    • Update on bone anabolics in osteoporosis treatment: Rationale, current status, and perspectives
    • Baron R, Hesse E (2012) Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives. J Clin Endocrinol Metab 97: 311-325.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 311-325
    • Baron, R.1    Hesse, E.2
  • 5
    • 77952704223 scopus 로고    scopus 로고
    • The use of PTH in the treatment of osteoporosis
    • Borba VZ, Manas NC (2010) The use of PTH in the treatment of osteoporosis. Arq Bras Endocrinol Metabol 54: 213-219.
    • (2010) Arq Bras Endocrinol Metabol , vol.54 , pp. 213-219
    • Borba, V.Z.1    Manas, N.C.2
  • 7
    • 33745884695 scopus 로고    scopus 로고
    • Anabolic agents: A new chapter in the management of osteoporosis
    • Khan AW, Khan A (2006) Anabolic agents: a new chapter in the management of osteoporosis. J Obstet Gynaecol Can 28: 136-141.
    • (2006) J Obstet Gynaecol Can , vol.28 , pp. 136-141
    • Khan, A.W.1    Khan, A.2
  • 8
    • 84890016169 scopus 로고    scopus 로고
    • Parathyroid Hormone and Parathyroid Hormone-Related Protein Analogs as Therapies for Osteoporosis
    • Augustine M, Horwitz MJ (2013) Parathyroid Hormone and Parathyroid Hormone-Related Protein Analogs as Therapies for Osteoporosis. Curr Osteoporos Rep.
    • (2013) Curr Osteoporos Rep
    • Augustine, M.1    Horwitz, M.J.2
  • 10
    • 0032512915 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein (PTHrP) and hypercalcaemia
    • DOI 10.1016/S0959-8049(97)10130-7, PII S0959804997101307
    • Grill V, Rankin W, Martin TJ (1998) Parathyroid hormone-related protein (PTHrP) and hypercalcaemia. Eur J Cancer 34: 222-229. (Pubitemid 28189190)
    • (1998) European Journal of Cancer , vol.34 , Issue.2 , pp. 222-229
    • Grill, V.1    Rankin, W.2    Martin, T.J.3
  • 12
    • 77950353316 scopus 로고    scopus 로고
    • Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice
    • Sun W, Liu J, Zhou X, Xiao Y, Karaplis A, et al. (2010) Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice. Development 137: 985-992.
    • (2010) Development , vol.137 , pp. 985-992
    • Sun, W.1    Liu, J.2    Zhou, X.3    Xiao, Y.4    Karaplis, A.5
  • 13
    • 80053453853 scopus 로고    scopus 로고
    • The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH
    • Liu J, Lv F, Sun W, Tao C, Ding G, et al. (2011) The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH. PLoS Genet 7: e1002294.
    • (2011) PLoS Genet , vol.7
    • Liu, J.1    Lv, F.2    Sun, W.3    Tao, C.4    Ding, G.5
  • 14
    • 0030465408 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor
    • Kovacs CS, Lanske B, Hunzelman JL, Guo J, Karaplis AC, et al. (1996) Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor. Proc Natl Acad Sci U S A 93: 15233-15238.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 15233-15238
    • Kovacs, C.S.1    Lanske, B.2    Hunzelman, J.L.3    Guo, J.4    Karaplis, A.C.5
  • 16
    • 58149481211 scopus 로고    scopus 로고
    • Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein
    • Miao D, Su H, He B, Gao J, Xia Q, et al. (2008) Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein. Proc Natl Acad Sci U S A 105: 20309-20314.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20309-20314
    • Miao, D.1    Su, H.2    He, B.3    Gao, J.4    Xia, Q.5
  • 17
    • 0027516448 scopus 로고
    • Long-term culture of disaggregated rat osteoclasts: Inhibition of bone resorption and reduction of osteoclast-like cell number by calcitonin and PTHrP[107-139]
    • Fenton AJ, Martin TJ, Nicholson GC (1993) Long-term culture of disaggregated rat osteoclasts: inhibition of bone resorption and reduction of osteoclast-like cell number by calcitonin and PTHrP[107-139]. J Cell Physiol 155: 1-7. (Pubitemid 23109050)
    • (1993) Journal of Cellular Physiology , vol.155 , Issue.1 , pp. 1-7
    • Fenton, A.J.1    Martin, T.J.2    Nicholson, G.C.3
  • 19
    • 25444520761 scopus 로고    scopus 로고
    • Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice
    • DOI 10.1359/JBMR.050608
    • Xue Y, Zhang Z, Karaplis AC, Hendy GN, Goltzman D, et al. (2005) Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice. J Bone Miner Res 20: 1766-1777. (Pubitemid 41361877)
    • (2005) Journal of Bone and Mineral Research , vol.20 , Issue.10 , pp. 1766-1777
    • Xue, Y.1    Zhang, Z.2    Karaplis, A.C.3    Hendy, G.N.4    Goltzman, D.5    Miao, D.6
  • 20
    • 0032768790 scopus 로고    scopus 로고
    • Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
    • DOI 10.1002/(SICI)1097-4652(199910)181:1<67::A
    • Conget PA, Minguell JJ (1999) Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol 181: 67-73. (Pubitemid 29400373)
    • (1999) Journal of Cellular Physiology , vol.181 , Issue.1 , pp. 67-73
    • Conget, P.A.1    Minguell, J.J.2
  • 21
    • 0030831553 scopus 로고    scopus 로고
    • 3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow
    • DOI 10.1210/en.138.11.4629
    • Erben RG, Scutt AM, Miao D, Kollenkirchen U, Haberey M (1997) Short-term treatment of rats with high dose 1,25-dihydroxyvitamin D3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow. Endocrinology 138: 4629-4635. (Pubitemid 27460897)
    • (1997) Endocrinology , vol.138 , Issue.11 , pp. 4629-4635
    • Erben, R.G.1    Scutt, A.M.2    Miao, D.3    Kollenkirchen, U.4    Haberey, M.5
  • 22
    • 20444472774 scopus 로고    scopus 로고
    • 3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development
    • DOI 10.1093/hmg/ddi160
    • Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D (2005) Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Hum Mol Genet 14: 1515-1528. (Pubitemid 40823460)
    • (2005) Human Molecular Genetics , vol.14 , Issue.11 , pp. 1515-1528
    • Xue, Y.1    Karaplis, A.C.2    Hendy, G.N.3    Goltzman, D.4    Miao, D.5
  • 23
    • 0035107364 scopus 로고    scopus 로고
    • Osteomalacia in Hyp mice is associated with abnormal Phex expression and with altered bone matrix protein expression and deposition
    • DOI 10.1210/en.142.2.926
    • Miao D, Bai X, Panda D, McKee M, Karaplis A, et al. (2001) Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. Endocrinology 142: 926-939. (Pubitemid 32222443)
    • (2001) Endocrinology , vol.142 , Issue.2 , pp. 926-939
    • Miao, D.1    Bai, X.2    Panda, D.3    McKee, M.D.4    Karaplis, A.C.5    Goltzman, D.6
  • 24
    • 1942469303 scopus 로고    scopus 로고
    • Inactivation of the 25-Hydroxyvitamin D 1alpha-Hydroxylase and Vitamin D Receptor Demonstrates Independent and Interdependent Effects of Calcium and Vitamin D on Skeletal and Mineral Homeostasis
    • DOI 10.1074/jbc.M310271200
    • Panda DK, Miao D, Bolivar I, Li J, Huo R, et al. (2004) Inactivation of the 25- hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. J Biol Chem 279: 16754-16766. (Pubitemid 38509378)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.16 , pp. 16754-16766
    • Panda, D.K.1    Miao, D.2    Bolivar, I.3    Li, J.4    Huo, R.5    Hendy, G.N.6    Goltzman, D.7
  • 25
    • 0036176152 scopus 로고    scopus 로고
    • Histochemical localization of alkaline phosphatase activity in decalcified bone and cartilage
    • Miao D, Scutt A (2002) Histochemical localization of alkaline phosphatase activity in decalcified bone and cartilage. J Histochem Cytochem 50: 333-340. (Pubitemid 34171058)
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.3 , pp. 333-340
    • Miao, D.1    Scutt, A.2
  • 26
    • 3342944925 scopus 로고    scopus 로고
    • Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo
    • Miao D, Scutt A (2002) Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo. BMC Musculoskelet Disord 3: 16.
    • (2002) BMC Musculoskelet Disord , vol.3 , pp. 16
    • Miao, D.1    Scutt, A.2
  • 27
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159. (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 28
    • 0036251217 scopus 로고    scopus 로고
    • Parathyroid hormone is essential for normal fetal bone formation
    • DOI 10.1172/JCI200214817
    • Miao D, He B, Karaplis AC, Goltzman D (2002) Parathyroid hormone is essential for normal fetal bone formation. J Clin Invest 109: 1173-1182. (Pubitemid 34496595)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.9 , pp. 1173-1182
    • Miao, D.1    He, B.2    Karaplis, A.C.3    Goltzman, D.4
  • 29
    • 84866145957 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein: An update
    • Wysolmerski JJ (2012) Parathyroid hormone-related protein: an update. J Clin Endocrinol Metab 97: 2947-2956.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 2947-2956
    • Wysolmerski, J.J.1
  • 30
    • 3843078530 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein: An essential physiological regulator of adult bone mass
    • DOI 10.1210/en.2004-0509
    • Bisello A, Horwitz MJ, Stewart AF (2004) Parathyroid hormone-related protein: an essential physiological regulator of adult bone mass. Endocrinology 145: 3551-3553. (Pubitemid 39037533)
    • (2004) Endocrinology , vol.145 , Issue.8 , pp. 3551-3553
    • Bisello, A.1    Horwitz, M.J.2    Stewart, A.F.3
  • 31
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
    • Abou-Samra AB, Juppner H, Force T, Freeman MW, Kong XF, et al. (1992) Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci U S A 89: 2732-2736.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 2732-2736
    • Abou-Samra, A.B.1    Juppner, H.2    Force, T.3    Freeman, M.W.4    Kong, X.F.5
  • 32
    • 0028940410 scopus 로고
    • Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: Effects of glucocorticoids
    • Walsh CA, Birch MA, Fraser WD, Lawton R, Dorgan J, et al. (1995) Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: effects of glucocorticoids. J Bone Miner Res 10: 17-25.
    • (1995) J Bone Miner Res , vol.10 , pp. 17-25
    • Walsh, C.A.1    Birch, M.A.2    Fraser, W.D.3    Lawton, R.4    Dorgan, J.5
  • 33
    • 64549098204 scopus 로고    scopus 로고
    • In vitro regulation of proliferation and differentiation within a postnatal growth plate of the cranial base by parathyroid hormone-related peptide (PTHrP)
    • Wealthall RJ (2009) In vitro regulation of proliferation and differentiation within a postnatal growth plate of the cranial base by parathyroid hormone-related peptide (PTHrP). J Cell Physiol 219: 688-697.
    • (2009) J Cell Physiol , vol.219 , pp. 688-697
    • Wealthall, R.J.1
  • 34
    • 0035943682 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway
    • Miao D, Tong XK, Chan GK, Panda D, McPherson PS, et al. (2001) Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway. J Biol Chem 276: 32204-32213.
    • (2001) J Biol Chem , vol.276 , pp. 32204-32213
    • Miao, D.1    Tong, X.K.2    Chan, G.K.3    Panda, D.4    McPherson, P.S.5
  • 35
    • 67349147522 scopus 로고    scopus 로고
    • PTH and PTHrP signaling in osteoblasts
    • Datta NS, Abou-Samra AB (2009) PTH and PTHrP signaling in osteoblasts. Cell Signal 21: 1245-1254.
    • (2009) Cell Signal , vol.21 , pp. 1245-1254
    • Datta, N.S.1    Abou-Samra, A.B.2
  • 36
    • 0031471679 scopus 로고    scopus 로고
    • Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation
    • DOI 10.1210/er.18.6.832
    • Kovacs CS, Kronenberg HM (1997) Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation. Endocr Rev 18: 832-872. (Pubitemid 28009569)
    • (1997) Endocrine Reviews , vol.18 , Issue.6 , pp. 832-872
    • Kovacs, C.S.1    Kronenberg, H.M.2
  • 38
    • 84862948326 scopus 로고    scopus 로고
    • Regulation and molecular mechanisms of calcium transport genes: Do they play a role in calcium transport in the uterine endometrium?
    • Choi KC, An BS, Yang H, Jeung EB (2011) Regulation and molecular mechanisms of calcium transport genes: do they play a role in calcium transport in the uterine endometrium? J Physiol Pharmacol 62: 499-504.
    • (2011) J Physiol Pharmacol , vol.62 , pp. 499-504
    • Choi, K.C.1    An, B.S.2    Yang, H.3    Jeung, E.B.4
  • 41
    • 59649096889 scopus 로고    scopus 로고
    • Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium
    • Cao G, Gu Z, Ren Y, Shu L, Tao C, et al. (2009) Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium. Endocrinology 150: 561-569.
    • (2009) Endocrinology , vol.150 , pp. 561-569
    • Cao, G.1    Gu, Z.2    Ren, Y.3    Shu, L.4    Tao, C.5
  • 42
    • 80054914956 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) contributes to regulating mammary calcium transport and modulates neonatal skeletal growth and turnover cooperatively with calcium
    • Ji J, Lu R, Zhou X, Xue Y, Shi C, et al. (2011) 1,25-Dihydroxyvitamin D(3) contributes to regulating mammary calcium transport and modulates neonatal skeletal growth and turnover cooperatively with calcium. Am J Physiol Endocrinol Metab 301: E889-900.
    • (2011) Am J Physiol Endocrinol Metab , vol.301
    • Ji, J.1    Lu, R.2    Zhou, X.3    Xue, Y.4    Shi, C.5
  • 43
    • 0030967201 scopus 로고    scopus 로고
    • Extracellular calcium and platelet-derived growth factor promote receptor-mediated chemotaxis in osteoblasts through different signaling pathways
    • DOI 10.1074/jbc.272.17.11307
    • Godwin SL, Soltoff SP (1997) Extracellular calcium and platelet-derived growth factor promote receptor-mediated chemotaxis in osteoblasts through different signaling pathways. J Biol Chem 272: 11307-11312. (Pubitemid 27184132)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.17 , pp. 11307-11312
    • Godwin, S.L.1    Soltoff, S.P.2
  • 44
    • 0031685091 scopus 로고    scopus 로고
    • 2+(o))-Sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells
    • DOI 10.1359/jbmr.1998.13.10.1530
    • Yamaguchi T, Chattopadhyay N, Kifor O, Butters RR Jr, Sugimoto T, et al. (1998) Mouse osteoblastic cell line (MC3T3-E1) expresses extracellular calcium (Ca2+o)-sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells. J Bone Miner Res 13: 1530-1538. (Pubitemid 28465293)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.10 , pp. 1530-1538
    • Yamaguchi, T.1    Chattopadhyay, N.2    Kifor, O.3    Butters Jr., R.R.4    Sugimoto, T.5    Brown, E.M.6
  • 46
    • 55749104922 scopus 로고    scopus 로고
    • The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development
    • Chang W, Tu C, Chen TH, Bikle D, Shoback D (2008) The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal 1: ra1.
    • (2008) Sci Signal , vol.1
    • Chang, W.1    Tu, C.2    Chen, T.H.3    Bikle, D.4    Shoback, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.