Parathyroid Hormone-related Peptide Stimulates Osteogenic Cell Proliferation through Protein Kinase C Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway

Journal of Biological Chemistry

Volumn 276, Issue 34, 2001, Pages 32204-32213

  Miao, Dengshun ^a   Tong, Xin Kang ^a   Chan, George K ^a   Panda, Dibyendu ^a   McPherson, Peter S ^a   Goltzman, David ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; ENZYME KINETICS; HORMONES; IMMUNOLOGY; NITROGEN; POLYPEPTIDES; PROTEINS;

CELL PROLIFERATION;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BROXURIDINE; CHELERYTHRINE; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; OSTEOCALCIN; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE INHIBITOR; RAS PROTEIN; SIALOPROTEIN; THYMIDINE; TRITIUM; WORTMANNIN; ALKALINE PHOSPHATASE; PARATHYROID HORMONE RELATED PROTEIN (1 34); PARATHYROID HORMONE-RELATED PROTEIN (1-34); PEPTIDE FRAGMENT; PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MINERALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; NONHUMAN; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL DIVISION; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; WISTAR RAT;

ANIMALIA;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MAP KINASE SIGNALING SYSTEM; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; PHENOTYPE; PROTEIN KINASE C; PROTEINS; RAS PROTEINS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0035943682     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101084200     Document Type: Article

References (56)

1. Reeve, J. (1996) J. Bone Miner. Res. 11, 440-445
2. Everhart-Caye, M., Inzucchi, S. E., Guinness-Henry, J., Mitnick, M. A., and Stewart, A. F. (1996) J. Clin. Endocrinol. & Metab. 81, 199-208
3. Fraher, L. J., Caveney, A. N., and McFadden, R. G. (1995) Am. J. Respir. Cell Mol. Biol. 12, 669-675
4. Henry, J. G., Mitnick, M., Dann, P. R., and Stewart, A. F. (1997) J. Clin. Endocrinol. & Metab. 82, 900-906
5. Hock, J. M., Fonseca, J., Gunness-Hey, M., Kemp, B. E., and Martin, T. J. (1989) Endocrinology 125, 2022-2027
6. Weir, E. C., Terwilliger, G., Sartori, L., and Insogna, K. L. (1992) Calcif. Tissue Int. 51, 30-34
7. Stewart, A. F. (1996) Bone 19, 303-306
8. Stewart, A. F., Cain, R. L., Burr, D. B., Jacob, D., Turner, C. H., and Hock, J. M. (2000) J. Bone Miner. Res. 15, 1517-1525
9. Plotkin, H., Gundberg, C., Mitnick, M., and Stewart, A. F. (1998) J. Clin. Endocrinol. & Metab. 83, 2786-2791
10. Vickery, B. H., Avnur, Z., Cheng, Y., Chiou, S. S., Leaffer, D., Caulfield, J. P., Kimmel, D. B., Ho, T., and Krstenansky, J. L. (1996) J. Bone Miner. Res. 11, 1943-1951
11. Leaffer, D., Sweeney, M., Kellerman, L. A., Avnur, Z., Krstenansky, J. L., Vickery, B. H., and Caulfield, J. P. (1995) Endocrinology 136, 3624-3631
12. Amizuka, N., Karaplis, A. C., Henderson, J. E., Warshawsky, H., Lipman, M. L., Matsuki, Y., Ejiri, S., Tanaka, M., Izumi, N., Ozawa, H., and Goltzman, D. (1996) Dev. Biol. 175, 166-176
13. Beresford, J. N. (1989) Clin. Orthop. 240, 270-280
14. Friedenstein, A. J., Chailakhyan, R. K., and Gerasimov, U. V. (1987) Cell Tissue Kinet. 20, 263-272
15. Malaval, L., Modrowski, D., Gupta, A. K., and Aubin, J. E. (1994) J. Cell. Physiol. 158, 555-572
16. Erben, R. G., Scutt, A. M., Miao, D., Kollenkirchen, U., and Haberey, M. (1997) Endocrinology 138, 4629-4635
17. Weinreb, M., Suponitzky, I., and Keila, S. (1997) Bone (NY) 20, 521-526
18. Nishida, S., Yamaguchi, A., Tanizawa, T., Endo, N., Mashiba, T., Uchiyama, Y., Suda, T., Yoshiki, S., and Takahashi, H. E. (1994) Bone (NY) 15, 717-723
19. Abou-Samra, A. B., Juppner, H., Force, T., Freeman, M. W., Kong, X. F., Schipani, E., Urena, P., Richards, J., Bonventre, J. V., Potts, J. T., Jr., Freeman, M., Kolakowski, L. F., Jr., Hock, J., and Kronenberg, H. M. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 2732-2736
20. Juppner, H., Abou-Samra, A. B., Freeman, M., Kong, X. F., Schipani, E., Richards, J., Kolakowski, L. F., Jr., Hock, J., Potts, J. T., Jr., Kronenberg, H. M., and Segre, G. V. (1991) Science 254, 1024-1026
21. Mannstadt, M., Juppner, H., and Gardella, T. J. (1999) Am. J. Physiol. 277, F665-F675
22. Morley, P., Whitfield, J. F., and Willick, G. E. (1999) Curr. Med. Chem. 6, 1095-1106
23. Goltzman, D. (1999) J. Bone Miner. Res. 14, 173-177
24. Verheijen, M. H., and Defize, L. H. (1997) J. Biol. Chem. 272, 3423-3429
25. Swarthout, J. T., Doggett, T. A., Lemker, J. L., and Partridge, N. C. (2001) J. Biol. Chem. 276, 7586-7592
26. Gutkind, J. S. (1998) J. Biol. Chem. 273, 1839-1842
27. Sugden, P. H., and Clerk, A. (1997) Cell. Signal. 9, 337-351
28. Boarder, M. R., and Hourani, S. M. (1998) Trends Pharmacol. Sci. 19, 99-107
29. Moolenaar, W. H., Kranenburg, O., Postma, F. R., and Zondag, G. C. (1997) Curr. Opin. Cell Biol. 9, 168-173
30. van Biesen, T., Luttrell, L. M., Hawes, B. E., and Lefkowitz, R. J. (1996) Endocr. Rev. 17, 698-714
31. Lefkowitz, R. J. (1998) J. Biol. Chem. 273, 18677-18680
32. Lopez-Ilasaca, M., Crespo, P., Pellici, P. G., Gutkind, J. S., and Wetzker, R. (1997) Science 275, 394-397
33. Della Rocca, G. J., van Biesen, T., Daaka, Y., Luttrell, D. K., Luttrell, L. M., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 19125-19132
34. Bianco, P., Fisher, L. W., Young, M. F., Termine, J. D., and Robey, P. G. (1991) Calcif. Tissue Int. 49, 421-426
35. Conget, P. A., and Minguell, J. J. (1999) J. Cell. Physiol. 181, 67-73
36. Miao, D., Bai, X., Panda, D., McKee, M. D., Karaplis, A. C., and Goltzman, D. (2001) Endocrinology 142, 926-939
37. Tong, X. K., Hussain, N. K., Adams, A. G., O'Bryan, J. P., and McPherson, P. S. (2000) J. Biol. Chem. 275, 29894-29899
38. Huang, H. M., Huang, C. J., and Yen, J. J. (2000) Blood 96, 1764-1771
39. de Rooij, J., and Bos, J. L. (1997) Oncogene 14, 623-625
40. Marais, R., Light, Y., Mason, C., Paterson, H., Olson, M. F., and Marshall, C. J. (1998) Science 280, 109-112
41. Tong, X. K., Hussain, N. K., de Heuvel, E., Kurakin, A., Abi-Jaoude, E., Quinn, C. C., Olson, M. F., Marais, R., Baranes, D., Kay, B. K., and McPherson, P. S. (2000) EMBO J. 19, 1263-1271
42. Altmannsberger, M., Osborn, M., Schauer, A., and Weber, K. (1981) Lab. Invest. 45, 427-434
43. Gown, A. M., and Vogel, A. M. (1982) J. Cell Biol. 95, 414-424
44. Eguchi, S., Matsumoto, T., Motley, E. D., Utsunomiya, H., and Inagami, T. (1996) J. Biol. Chem. 271, 14169-14175
45. Cherniack, A. D., Klarlund, J. K., Conway, B. R., and Czech, M. P. (1995) J. Biol. Chem. 270, 1485-1488
46. Waters, S. B., Chen, D., Kao, A. W., Okada, S., Holt, K. H., and Pessin, J. E. (1996) J. Biol. Chem. 271, 18224-18230
47. Aubin, J. E., Liu, F., Malaval, L., and Gupta, A. K. (1995) Bone (Suppl. 2) 17, 77-83
48. Stein, G. S., and Lian, J. B. (1993) Endocr. Rev. 14, 424-442
49. Jilka, R. L., Weinstein, R. S., Bellido, T., Roberson, P., Parfitt, A. M., and Manolagas, S. C. (1999) J. Clin. Invest. 104, 439-446
50. Stewart, A. F., Vignery, A., Silverglate, A., Ravin, N. D., LiVolsi, V., Broadus, A. E., and Baron, R. (1982) J. Clin. Endocrinol. & Metab. 55, 219-227
51. Cole, J. A. (1999) Endocrinology 140, 5771-5779
52. Daaka, Y., Luttrell, L. M., Ahn, S., Della Rocca, G. J., Ferguson, S. S., Caron, M. G., and Letkowitz, R. J. (1998) J. Biol. Chem. 273, 685-688
53. Gutkind, J. S. (1998) Oncogene 17, 1331-1342
54. Karaplis, A. C., and Goltzman, D. (1999) in PTHrP: Of Molecules, Mice, and Men (Seibel, J. M., Robins, S. P., and Bilezikian, J. P., eds) pp. 397-428, Academic Press, San Diego
55. Kolch, W., Heidecker, G., Kochs, G., Hummel, R., Vahidi, H., Mischak, H., Finkenzeller, G., Marme, D., and Rapp, U. R. (1993) Nature 364, 249-252
56. Sato, H., Ogata, H., and De Luca, L. M. (2000) Oncogene 19, 2904-2912