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Volumn 5, Issue 3, 2014, Pages 386-396

Comparative mode-of-action analysis following manual and automated phenotype detection in Xenopus laevis

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; AUTOMATION; COMPARATIVE STUDY; COMPUTER MODEL; DECISION TREE; EMBRYO; EYE DEVELOPMENT; IMAGE ANALYSIS; MORPHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TADPOLE; XENOPUS LAEVIS;

EID: 84895169509     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c3md00313b     Document Type: Article
Times cited : (4)

References (73)
  • 1
    • 84876069345 scopus 로고    scopus 로고
    • Phenotypic screening, take two
    • J. Kotz Phenotypic screening, take two J. SciBX 2012 5 1 3
    • (2012) J. SciBX , vol.5 , pp. 1-3
    • Kotz, J.1
  • 2
    • 67650070045 scopus 로고    scopus 로고
    • Multi-parameter phenotypic profiling: Using cellular effects to characterize small-molecule compounds
    • Y. Feng T. J. Mitchison A. Bender D. W. Young J. A. Tallarico Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds Nat. Rev. Drug Discovery 2009 8 567 578
    • (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 567-578
    • Feng, Y.1    Mitchison, T.J.2    Bender, A.3    Young, D.W.4    Tallarico, J.A.5
  • 3
    • 33748742351 scopus 로고    scopus 로고
    • High-content screening moves to the front of the line
    • S. A. Haney P. LaPan J. Pan J. Zhang High-content screening moves to the front of the line Drug Discovery Today 2006 11 889 894
    • (2006) Drug Discovery Today , vol.11 , pp. 889-894
    • Haney, S.A.1    Lapan, P.2    Pan, J.3    Zhang, J.4
  • 4
    • 75549084662 scopus 로고    scopus 로고
    • Et al., EuroPhenome: A repository for high-throughput mouse phenotyping data
    • H. Morgan et al., EuroPhenome: a repository for high-throughput mouse phenotyping data Nucleic Acids Res. 2010 38 D577 D585
    • (2010) Nucleic Acids Res. , vol.38
    • Morgan, H.1
  • 5
    • 79956295350 scopus 로고    scopus 로고
    • Et al., Case definition and phenotype standardization in drug-induced liver injury
    • G. P. Aithal et al., Case definition and phenotype standardization in drug-induced liver injury Clin. Pharmacol. Ther. 2011 89 806 815
    • (2011) Clin. Pharmacol. Ther. , vol.89 , pp. 806-815
    • Aithal, G.P.1
  • 6
    • 84856095231 scopus 로고    scopus 로고
    • Et al., Chemical informatics and target identification in a zebrafish phenotypic screen
    • C. Laggner et al., Chemical informatics and target identification in a zebrafish phenotypic screen Nat. Chem. Biol. 2012 8 144 146
    • (2012) Nat. Chem. Biol. , vol.8 , pp. 144-146
    • Laggner, C.1
  • 7
    • 37249026328 scopus 로고    scopus 로고
    • Et al., Integrating high-content screening and ligand-target prediction to identify mechanism of action
    • D. W. Young et al., Integrating high-content screening and ligand-target prediction to identify mechanism of action Nat. Chem. Biol. 2008 4 59 68
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 59-68
    • Young, D.W.1
  • 8
    • 66349132028 scopus 로고    scopus 로고
    • An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis
    • R. E. Kälin N. E. Bänziger-Tobler M. Detmar A. W. Brändli An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis Blood 2009 114 1110 1122
    • (2009) Blood , vol.114 , pp. 1110-1122
    • Kälin, R.E.1    Bänziger-Tobler, N.E.2    Detmar, M.3    Brändli, A.W.4
  • 9
    • 66349117984 scopus 로고    scopus 로고
    • Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish and Xenopus
    • G. N. Wheeler A. W. Brändli Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus Dev. Dyn. 2009 238 1287 1308
    • (2009) Dev. Dyn. , vol.238 , pp. 1287-1308
    • Wheeler, G.N.1    Brändli, A.W.2
  • 11
    • 62949098600 scopus 로고    scopus 로고
    • Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development
    • M. L. Tomlinson M. Rejzek M. Fidock R. Field G. N. Wheeler Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development Mol. BioSyst. 2009 5 376 384
    • (2009) Mol. BioSyst. , vol.5 , pp. 376-384
    • Tomlinson, M.L.1    Rejzek, M.2    Fidock, M.3    Field, R.4    Wheeler, G.N.5
  • 12
    • 0346158531 scopus 로고    scopus 로고
    • High content screening applied to large-scale cell biology
    • V. C. Abraham D. L. Taylor J. R. Haskins High content screening applied to large-scale cell biology Trends Biotechnol. 2004 22 15 22
    • (2004) Trends Biotechnol. , vol.22 , pp. 15-22
    • Abraham, V.C.1    Taylor, D.L.2    Haskins, J.R.3
  • 13
    • 33845792555 scopus 로고    scopus 로고
    • Et al., CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
    • A. E. Carpenter et al., CellProfiler: image analysis software for identifying and quantifying cell phenotypes Genome Biol. 2006 7 R100
    • (2006) Genome Biol. , vol.7 , pp. 100
    • Carpenter, A.E.1
  • 14
    • 21844444534 scopus 로고    scopus 로고
    • Feature extraction for cellular shape analysis in high-content screening (HCS) applications
    • B. Bayraktar B. Rajwa J. P. Robinson Feature extraction for cellular shape analysis in high-content screening (HCS) applications Proc. SPIE 2005 5699 342 353
    • (2005) Proc. SPIE , vol.5699 , pp. 342-353
    • Bayraktar, B.1    Rajwa, B.2    Robinson, J.P.3
  • 15
    • 80155177215 scopus 로고    scopus 로고
    • High-content analysis in monastrol suppressor screens. A neural network-based classification approach
    • Z. Zhang Y. Ge D. Zhang X. Zhou High-content analysis in monastrol suppressor screens. A neural network-based classification approach Methods Inf. Med. 2011 50 265 272
    • (2011) Methods Inf. Med. , vol.50 , pp. 265-272
    • Zhang, Z.1    Ge, Y.2    Zhang, D.3    Zhou, X.4
  • 16
    • 33947395259 scopus 로고    scopus 로고
    • High-content siRNA screening
    • E. Krausz High-content siRNA screening Mol. BioSyst. 2007 3 232 240
    • (2007) Mol. BioSyst. , vol.3 , pp. 232-240
    • Krausz, E.1
  • 17
    • 33646057010 scopus 로고    scopus 로고
    • Et al., High-throughput RNAi screening by time-lapse imaging of live human cells
    • B. Neumann et al., High-throughput RNAi screening by time-lapse imaging of live human cells Nat. Methods 2006 3 385 390
    • (2006) Nat. Methods , vol.3 , pp. 385-390
    • Neumann, B.1
  • 18
    • 77956278335 scopus 로고    scopus 로고
    • High-magnification in vivo imaging of Xenopus embryos for cell and developmental biology
    • 10.1101/pdb.prot5427
    • E. K. Kieserman C. Lee R. S. Gray T. J. Park J. B. Wallingford High-magnification in vivo imaging of Xenopus embryos for cell and developmental biology Cold Spring Harb. Protoc. 2010 10.1101/pdb.prot5427
    • (2010) Cold Spring Harb. Protoc.
    • Kieserman, E.K.1    Lee, C.2    Gray, R.S.3    Park, T.J.4    Wallingford, J.B.5
  • 19
    • 84875884160 scopus 로고    scopus 로고
    • Investigating morphogenesis in Xenopus embryos: Imaging strategies, processing, and analysis
    • H. Y. Kim L. A. Davidson Investigating morphogenesis in Xenopus embryos: imaging strategies, processing, and analysis Cold Spring Harb. Protoc. 2013 2013 298 304
    • (2013) Cold Spring Harb. Protoc. , vol.2013 , pp. 298-304
    • Kim, H.Y.1    Davidson, L.A.2
  • 20
    • 37549033073 scopus 로고    scopus 로고
    • Et al., Multimodality optical imaging of embryonic heart microstructure
    • R. Yelin et al., Multimodality optical imaging of embryonic heart microstructure J. Biomed. Opt. 2007 12 1 28
    • (2007) J. Biomed. Opt. , vol.12 , pp. 1-28
    • Yelin, R.1
  • 21
    • 33745698558 scopus 로고    scopus 로고
    • Et al., Genetic screens for mutations affecting development of Xenopus tropicalis
    • T. Goda et al., Genetic screens for mutations affecting development of Xenopus tropicalis PLoS Genet. 2006 2 e91
    • (2006) PLoS Genet. , vol.2 , pp. 91
    • Goda, T.1
  • 22
    • 33751359804 scopus 로고    scopus 로고
    • Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides
    • A. A. Rana C. Collart M. J. Gilchrist J. C. Smith Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides PLoS Genet. 2006 2 e193
    • (2006) PLoS Genet. , vol.2 , pp. 193
    • Rana, A.A.1    Collart, C.2    Gilchrist, M.J.3    Smith, J.C.4
  • 23
    • 0034068307 scopus 로고    scopus 로고
    • Zebrafish: A model system for the study of human disease
    • K. Dooley L. I. Zon Zebrafish: a model system for the study of human disease Curr. Opin. Genet. Dev. 2000 10 252 256
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 252-256
    • Dooley, K.1    Zon, L.I.2
  • 24
    • 61649105020 scopus 로고    scopus 로고
    • Et al., Automated image-based phenotypic analysis in zebrafish embryos
    • A. Vogt et al., Automated image-based phenotypic analysis in zebrafish embryos Dev. Dyn. 2009 238 656 663
    • (2009) Dev. Dyn. , vol.238 , pp. 656-663
    • Vogt, A.1
  • 25
    • 84886817483 scopus 로고    scopus 로고
    • Et al., ZebIAT, an image analysis tool for registering zebrafish embryos and quantifying cancer metastasis
    • T. Annila et al., ZebIAT, an image analysis tool for registering zebrafish embryos and quantifying cancer metastasis BMC Bioinf. 2013 14 S5
    • (2013) BMC Bioinf. , vol.14 , pp. 5
    • Annila, T.1
  • 26
    • 84871775140 scopus 로고    scopus 로고
    • Computational techniques in zebrafish image processing and analysis
    • S. Xia Y. Zhu X. Xu W. Xia Computational techniques in zebrafish image processing and analysis J. Neurosci. Methods 2013 213 6 13
    • (2013) J. Neurosci. Methods , vol.213 , pp. 6-13
    • Xia, S.1    Zhu, Y.2    Xu, X.3    Xia, W.4
  • 27
    • 84883394740 scopus 로고    scopus 로고
    • Et al., Automated processing of zebrafish imaging data: A survey
    • R. Mikut et al., Automated processing of zebrafish imaging data: a survey Zebrafish 2013 10 401 421
    • (2013) Zebrafish , vol.10 , pp. 401-421
    • Mikut, R.1
  • 28
    • 84869744217 scopus 로고    scopus 로고
    • Et al., Inside the mind of a medicinal chemist: The role of human bias in compound prioritization during drug discovery
    • P. S. Kutchukian et al., Inside the mind of a medicinal chemist: the role of human bias in compound prioritization during drug discovery PLoS One 2012 7 e48476
    • (2012) PLoS One , vol.7 , pp. 48476
    • Kutchukian, P.S.1
  • 29
    • 4544338170 scopus 로고    scopus 로고
    • Assessment of the consistency of medicinal chemists in reviewing sets of compounds
    • M. S. Lajiness G. M. Maggiora V. Shanmugasundaram Assessment of the consistency of medicinal chemists in reviewing sets of compounds J. Med. Chem. 2004 47 4891 4896
    • (2004) J. Med. Chem. , vol.47 , pp. 4891-4896
    • Lajiness, M.S.1    Maggiora, G.M.2    Shanmugasundaram, V.3
  • 30
    • 84856292873 scopus 로고    scopus 로고
    • Workflow and metrics for image quality control in large-scale high-content screens
    • M. A. Bray A. N. Fraser T. P. Hasaka A. E. Carpenter Workflow and metrics for image quality control in large-scale high-content screens J Biomol Screen 2012 17 266 274
    • (2012) J Biomol Screen , vol.17 , pp. 266-274
    • Bray, M.A.1    Fraser, A.N.2    Hasaka, T.P.3    Carpenter, A.E.4
  • 31
    • 84894539238 scopus 로고    scopus 로고
    • Et al., Extensions to in Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts
    • S. Liggi et al., Extensions to In Silico Bioactivity Predictions Using Pathway Annotations and Differential Pharmacology Analysis: Application to Xenopus laevis Phenotypic Readouts Mol. Inf. 2013 32 11-12 1009 1024
    • (2013) Mol. Inf. , vol.32 , Issue.1112 , pp. 1009-1024
    • Liggi, S.1
  • 32
    • 84871756440 scopus 로고    scopus 로고
    • Et al., Experimental validation of in silico target predictions on synergistic protein targets
    • I. Cortes-Ciriano et al., Experimental validation of in silico target predictions on synergistic protein targets MedChemComm 2013 4 278
    • (2013) MedChemComm , vol.4 , pp. 278
    • Cortes-Ciriano, I.1
  • 33
    • 27344435774 scopus 로고    scopus 로고
    • Et al., Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide
    • A. Subramanian et al., Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide Proc. Natl. Acad. Sci. U. S. A. 2005 102 15545 15550
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 34
    • 81055140589 scopus 로고    scopus 로고
    • Et al., from in silico target prediction to multi-target drug design: Current databases, methods and applications
    • A. Koutsoukas et al., From in silico target prediction to multi-target drug design: Current databases, methods and applications J. Proteomics 2011 74 2554 2574
    • (2011) J. Proteomics , vol.74 , pp. 2554-2574
    • Koutsoukas, A.1
  • 35
    • 33846876695 scopus 로고    scopus 로고
    • Et al., Relating protein pharmacology by ligand chemistry
    • M. J. Keiser et al., Relating protein pharmacology by ligand chemistry Nat. Biotechnol. 2007 25 197 206
    • (2007) Nat. Biotechnol. , vol.25 , pp. 197-206
    • Keiser, M.J.1
  • 36
    • 70449634957 scopus 로고    scopus 로고
    • Et al., Predicting new molecular targets for known drugs
    • M. J. Keiser et al., Predicting new molecular targets for known drugs Nature 2009 462 175 181
    • (2009) Nature , vol.462 , pp. 175-181
    • Keiser, M.J.1
  • 37
    • 33750339874 scopus 로고    scopus 로고
    • Parallel screening: A novel concept in pharmacophore modeling and virtual screening
    • T. M. Steindl D. Schuster C. Laggner T. Langer Parallel screening: a novel concept in pharmacophore modeling and virtual screening J. Chem. Inf. Model. 2006 46 2146 2157
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 2146-2157
    • Steindl, T.M.1    Schuster, D.2    Laggner, C.3    Langer, T.4
  • 38
    • 33645822986 scopus 로고    scopus 로고
    • Development and validation of an in silico P450 profiler based on pharmacophore models
    • D. Schuster C. Laggner T. M. Steindl T. Langer Development and validation of an in silico P450 profiler based on pharmacophore models Curr. Drug Discovery Technol. 2006 3 1 48
    • (2006) Curr. Drug Discovery Technol. , vol.3 , pp. 1-48
    • Schuster, D.1    Laggner, C.2    Steindl, T.M.3    Langer, T.4
  • 39
    • 33244482848 scopus 로고    scopus 로고
    • Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and Laplacian-modified naive bayesian classifiers
    • M. Glick J. L. Jenkins J. H. Nettles H. Hitchings J. W. Davies Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and Laplacian-modified naive bayesian classifiers J. Chem. Inf. Model. 2006 46 193 200
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 193-200
    • Glick, M.1    Jenkins, J.L.2    Nettles, J.H.3    Hitchings, H.4    Davies, J.W.5
  • 40
    • 84883239935 scopus 로고    scopus 로고
    • Et al., in silico target predictions: Comparing multiclass Naïve Bayes and Parzen-Rosenblatt Window and the definition of a benchmarking dataset for target prediction
    • A. Koutsoukas et al., In silico target predictions: comparing multiclass Naïve Bayes and Parzen-Rosenblatt Window and the definition of a benchmarking dataset for target prediction J. Chem. Inf. Model. 2013 53 1957 1966
    • (2013) J. Chem. Inf. Model. , vol.53 , pp. 1957-1966
    • Koutsoukas, A.1
  • 41
    • 33745391215 scopus 로고    scopus 로고
    • Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases
    • Nidhi M. Glick J. W. Davies J. L. Jenkins Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases J. Chem. Inf. Model. 2006 46 1124 1133
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 1124-1133
    • Nidhi1    Glick, M.2    Davies, J.W.3    Jenkins, J.L.4
  • 42
    • 58149116805 scopus 로고    scopus 로고
    • Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics
    • F. Nigsch A. Bender J. L. Jenkins J. B. O. Mitchell Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics J. Chem. Inf. Model. 2008 48 2313 2325
    • (2008) J. Chem. Inf. Model. , vol.48 , pp. 2313-2325
    • Nigsch, F.1    Bender, A.2    Jenkins, J.L.3    Mitchell, J.B.O.4
  • 44
    • 77956837481 scopus 로고    scopus 로고
    • In Silico Receptorome Screening of Antipsychotic Drugs
    • D. Vidal J. Mestres In Silico Receptorome Screening of Antipsychotic Drugs Mol. Inf. 2010 29 543 551
    • (2010) Mol. Inf. , vol.29 , pp. 543-551
    • Vidal, D.1    Mestres, J.2
  • 45
    • 84895118941 scopus 로고    scopus 로고
    • NCI Repositories, Diversity Set Information, accessed 30 May 2013
    • NCI Repositories, Diversity Set Information, http://dtp.nci.nih.gov/ branches/dscb/div2-explanation.html, accessed 30 May 2013
  • 46
    • 84895182619 scopus 로고    scopus 로고
    • Open Source Computer Vision, OpenCV
    • Open Source Computer Vision, OpenCV, 2013, http://opencv.org
    • (2013)
  • 49
    • 0022267462 scopus 로고
    • Topological Structural Analysis of Digitized Binary Images by Border Following
    • S. Suzuki K. Abe Topological Structural Analysis of Digitized Binary Images by Border Following Comput Vision Graph 1985 46 32 46
    • (1985) Comput Vision Graph , vol.46 , pp. 32-46
    • Suzuki, S.1    Abe, K.2
  • 52
    • 0015285440 scopus 로고
    • Use of the Hough Transformation to Detect Lines and Curves in Pictures
    • R. O. Duda P. E. Hart Use of the Hough Transformation to Detect Lines and Curves in Pictures Commun. ACM 1972 15 11 15
    • (1972) Commun. ACM , vol.15 , pp. 11-15
    • Duda, R.O.1    Hart, P.E.2
  • 55
    • 84856370732 scopus 로고    scopus 로고
    • Et al., ChEMBL: A large-scale bioactivity database for drug discovery
    • A. Gaulton et al., ChEMBL: a large-scale bioactivity database for drug discovery Nucleic Acids Res. 2011 44 1 8
    • (2011) Nucleic Acids Res. , vol.44 , pp. 1-8
    • Gaulton, A.1
  • 58
    • 0036501591 scopus 로고    scopus 로고
    • Et al., Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa
    • S. J. Bowne et al., Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa Hum. Mol. Genet. 2002 11 559 568
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 559-568
    • Bowne, S.J.1
  • 60
    • 79953138420 scopus 로고    scopus 로고
    • Et al., Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion
    • H. J. Shin et al., Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion J. Cell Sci. 2011 124 1077 1087
    • (2011) J. Cell Sci. , vol.124 , pp. 1077-1087
    • Shin, H.J.1
  • 61
    • 84895191845 scopus 로고    scopus 로고
    • Et al., Melatonin, the hormone of darkness: A ray of Hope for Many Diseases
    • P. R. Shankar et al., Melatonin, the hormone of darkness: A ray of Hope for Many Diseases Pharmacologyonline 2006 2 274 289
    • (2006) Pharmacologyonline , vol.2 , pp. 274-289
    • Shankar, P.R.1
  • 62
    • 0021858058 scopus 로고
    • Differential in vivo Sensitivity of Melanophores and Xanthophores to Catecholamines in Winter Flounder (Pseudopleuronectes americanus Walbaum) Integumentary Patterns
    • D. Burton Differential in vivo Sensitivity of Melanophores and Xanthophores to Catecholamines in Winter Flounder (Pseudopleuronectes americanus Walbaum) Integumentary Patterns J. Exp. Biol. 1985 114 649 659
    • (1985) J. Exp. Biol. , vol.114 , pp. 649-659
    • Burton, D.1
  • 63
    • 0026510268 scopus 로고
    • Demonstration of Coexisting Catecholamine (Dopamine), Amino Acid (GABA), and Peptide (NPY) Involved in Inhibition of Melanotrope Cell Activity in Xenopus Levis: A Quantitative Ultrastructural, lmmunocytochemical Study
    • E. P. C. T. De Rijk F. J. C. van Strien E. W. Roubos Demonstration of Coexisting Catecholamine (Dopamine), Amino Acid (GABA), and Peptide (NPY) Involved in Inhibition of Melanotrope Cell Activity in Xenopus Levis: A Quantitative Ultrastructural, lmmunocytochemical Study J. Neurosci. 1992 12 864 871
    • (1992) J. Neurosci. , vol.12 , pp. 864-871
    • De Rijk, E.P.C.T.1    Van Strien, F.J.C.2    Roubos, E.W.3
  • 64
    • 0022980820 scopus 로고
    • Pigment Granule Migration in Isolated Cells of the Teleost Retinal Pigment Epithelium
    • U. Druenner B. Burnside Pigment Granule Migration in Isolated Cells of the Teleost Retinal Pigment Epithelium Invest. Ophthalmol. Visual Sci. 1986 27 1634 1643
    • (1986) Invest. Ophthalmol. Visual Sci. , vol.27 , pp. 1634-1643
    • Druenner, U.1    Burnside, B.2
  • 66
    • 77954649705 scopus 로고    scopus 로고
    • Transcription physiology of pigment formation in melanocytes: Central role of MITF
    • J. Vachtenheim J. Borovanský "Transcription physiology" of pigment formation in melanocytes: central role of MITF Exp. Dermatol. 2010 19 617 627
    • (2010) Exp. Dermatol. , vol.19 , pp. 617-627
    • Vachtenheim, J.1    Borovanský, J.2
  • 68
    • 0029832438 scopus 로고    scopus 로고
    • Et al., Lipocalin-Type Prostaglandin D Synthase (beta-Trace) Is Located in Pigment Epithelial Cells of Rat Retina and Accumulates within Interphotoreceptor Matrix
    • C. T. Beuckmann et al., Lipocalin-Type Prostaglandin D Synthase (beta-Trace) Is Located in Pigment Epithelial Cells of Rat Retina and Accumulates within Interphotoreceptor Matrix J. Neurosci. 1996 16 6119 6124
    • (1996) J. Neurosci. , vol.16 , pp. 6119-6124
    • Beuckmann, C.T.1
  • 69
    • 34548834687 scopus 로고    scopus 로고
    • Et al., Regulation of arterial lesions in mice depends on differential smooth muscle cell migration: A role for sphingosine-1-phosphate receptors
    • S. Inoue et al., Regulation of arterial lesions in mice depends on differential smooth muscle cell migration: a role for sphingosine-1-phosphate receptors Vasc. Surg. 2007 46 756 763
    • (2007) Vasc. Surg. , vol.46 , pp. 756-763
    • Inoue, S.1
  • 70
    • 33646023697 scopus 로고    scopus 로고
    • Et al., Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts
    • L. Becciolini et al., Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts Biochim. Biophys. Acta 2006 1761 43 51
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 43-51
    • Becciolini, L.1
  • 71
    • 77953289068 scopus 로고    scopus 로고
    • S1P metabolism in cancer and other pathological conditions
    • W. I. Leong J. D. Saba S1P metabolism in cancer and other pathological conditions Biochimie 2010 92 716 723
    • (2010) Biochimie , vol.92 , pp. 716-723
    • Leong, W.I.1    Saba, J.D.2
  • 72
    • 84895160791 scopus 로고    scopus 로고
    • in Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues-From Molecules to Humans, InTech, 10.5772/48256
    • S. Salim and S. A. Ali, Melanophores: Smooth Muscle Cells in Disguise, in Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues-From Molecules to Humans, InTech, 2012, 10.5772/48256
    • (2012) Melanophores: Smooth Muscle Cells in Disguise
    • Salim, S.1    Ali, S.A.2
  • 73
    • 0038025417 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation
    • D. S. Kim Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation J. Cell Sci. 2003 116 1699 1706
    • (2003) J. Cell Sci. , vol.116 , pp. 1699-1706
    • Kim, D.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.