Acute exposure to lead acetate activates microglia and induces subsequent bystander neuronal death via caspase-3 activation

NeuroToxicology

Volumn 41, Issue , 2014, Pages 143-153

  Kumawat, Kanhaiya Lal ^a,b   Kaushik, Deepak Kumar ^a   Goswami, Praveen ^b,c   Basu, Anirban ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

^b DrKNModi University   (India)

^c Poddar Group of Institutions   (India)

Author keywords

Apoptosis; Central nervous system; COX 2; Lead; Microglia; NF B

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LEAD ACETATE; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

ACUTE TOXICITY; ANIMAL CELL; APOPTOSIS; ARTICLE; BYSTANDER EFFECT; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; LEAD POISONING; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

APOPTOSIS; CENTRAL NERVOUS SYSTEM; COX-2; LEAD; MICROGLIA; NF-ΚB;

ANALYSIS OF VARIANCE; ANIMALS; CASPASE 3; CELL DEATH; CELL LINE, TRANSFORMED; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; CYCLOOXYGENASE 2; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; MAP KINASE KINASE KINASE 5; MICE; MICROGLIA; MOLECULAR WEIGHT; NEURONS; ORGANOMETALLIC COMPOUNDS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84895140630     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.02.002     Document Type: Article

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