Involvement of the epidermal growth factor receptor in Pb2+-induced activation of cPLA2/COX-2 genes and PGE2 production in vascular smooth muscle cells

Toxicology

Volumn 279, Issue 1-3, 2011, Pages 45-53

  Chang, Wei Chiao ^a,b   Chang, Chen Chia ^a   Wang, Yung Song ^a   Wang, Yu Shiuan ^a   Weng, Wei Teng ^a   Yoshioka, Tohru ^b   Juo, Suh Hang Hank ^a,b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

COX 2; CPLA2; EGFR; Lead; MAPKs; PGE2; SOC

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; EPIDERMAL GROWTH FACTOR RECEPTOR; LEAD; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROSTAGLANDIN E2; VASCULOTROPIN RECEPTOR;

ARTICLE; CARDIOVASCULAR DISEASE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; POLLUTANT; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

AORTA; CELL LINE; CELL MEMBRANE; CYCLOOXYGENASE 2; DINOPROSTONE; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LEAD; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; NITRATES; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 78649983461     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.09.004     Document Type: Article

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