-
1
-
-
0034695441
-
Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras
-
Abe J-i, Okuda M, Huang Q, Yoshizumi M, Berk BC (2000) Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. J Biol Chem 275:1739-48
-
(2000)
J Biol Chem
, vol.275
, pp. 1739-1748
-
-
Abe, J.-I.1
Okuda, M.2
Huang, Q.3
Yoshizumi, M.4
Berk, B.C.5
-
2
-
-
0036263338
-
Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia
-
Asai A, Tanahashi N, Qiu J-h, Saito N, Chi S, Kawahara N et al (2002) Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia. J Cereb Blood Flow Metab 22:705-10
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 705-710
-
-
Asai, A.1
Tanahashi, N.2
Qiu, J.-H.3
Saito, N.4
Chi, S.5
Kawahara, N.6
-
3
-
-
0030222080
-
Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor
-
Barger SW, Mattson MP (1996) Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor. Brain Res Mol Brain Res 40:116-26
-
(1996)
Brain Res Mol Brain Res
, vol.40
, pp. 116-126
-
-
Barger, S.W.1
Mattson, M.P.2
-
4
-
-
0033144253
-
Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity
-
Botchkina GI, Geimonen E, Bilof ML, Villarreal O, Tracey KJ (1999) Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity. Mol Med 5:372-81
-
(1999)
Mol Med
, vol.5
, pp. 372-381
-
-
Botchkina, G.I.1
Geimonen, E.2
Bilof, M.L.3
Villarreal, O.4
Tracey, K.J.5
-
5
-
-
0037108119
-
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke
-
Bowler RP, Sheng H, Enghild JJ, Pearlstein RD, Warner DS, Crapo JD (2002) A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. Free Radic Biol Med 33:1141-52
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1141-1152
-
-
Bowler, R.P.1
Sheng, H.2
Enghild, J.J.3
Pearlstein, R.D.4
Warner, D.S.5
Crapo, J.D.6
-
6
-
-
0008587780
-
Nuclear factor-κB activation during cerebral reperfusion: Effect of attenuation with N-acetylcysteine treatment
-
Carroll JE, Howard EF, Hess DC, Wakade CG., Chen Q, Cheng C (1998) Nuclear factor-κB activation during cerebral reperfusion: effect of attenuation with N-acetylcysteine treatment. Brain Res Mol Brain Res 56:186-91
-
(1998)
Brain Res Mol Brain Res
, vol.56
, pp. 186-191
-
-
Carroll, J.E.1
Howard, E.F.2
Hess, D.C.3
Wakade, C.G.4
Chen, Q.5
Cheng, C.6
-
7
-
-
1542571786
-
Signal-induced ubiquitination of IκB kinase-β
-
Carter RS, Pennington KN, Ungurait BJ, Arrate P, Ballard DW (2003) Signal-induced ubiquitination of IκB kinase-β. J Biol Chem 278:48903-6
-
(2003)
J Biol Chem
, vol.278
, pp. 48903-48906
-
-
Carter, R.S.1
Pennington, K.N.2
Ungurait, B.J.3
Arrate, P.4
Ballard, D.W.5
-
8
-
-
0029888311
-
Role of oxidants in ischemic brain damage
-
Chan PH (1996) Role of oxidants in ischemic brain damage. Stroke 27:1124-9
-
(1996)
Stroke
, vol.27
, pp. 1124-1129
-
-
Chan, P.H.1
-
9
-
-
0036805108
-
Signaling from toxic metals to NF-kappaB and beyond: Not just a matter of reactive oxygen species
-
Chen F, Shi X (2002) Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species. Environ Health Perspect 110(Suppl 5):807-11
-
(2002)
Environ Health Perspect
, vol.110
, Issue.5 SUPPL.
, pp. 807-811
-
-
Chen, F.1
Shi, X.2
-
10
-
-
0029146930
-
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway
-
Chen Z, Hagler J, Palombella VJ, Melandri F, Scherer D, Ballard D et al (1995) Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway. Genes Dev 9:1586-97
-
(1995)
Genes Dev
, vol.9
, pp. 1586-1597
-
-
Chen, Z.1
Hagler, J.2
Palombella, V.J.3
Melandri, F.4
Scherer, D.5
Ballard, D.6
-
11
-
-
0030004897
-
Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity
-
Chen ZJ, Parent L, Maniatis T (1996) Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity. Cell 84:853-62
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
12
-
-
0034656846
-
Cerebral ischemia: Gene activation, neuronal injury, and the protective role of antioxidants
-
Clemens JA (2000) Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants. Free Radic Biol Med 28:1526-31
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1526-1531
-
-
Clemens, J.A.1
-
13
-
-
0030766036
-
Global cerebral ischemia activates nuclear factor-κB prior toevidence of DNA fragmentation
-
Clemens JA, Stephenson DT, Dixon EP, Smalstig EB, Mincy RE, Rash KS et al (1997) Global cerebral ischemia activates nuclear factor-κB prior toevidence of DNA fragmentation. Brain Res Mol Brain Res 48:187-196
-
(1997)
Brain Res Mol Brain Res
, vol.48
, pp. 187-196
-
-
Clemens, J.A.1
Stephenson, D.T.2
Dixon, E.P.3
Smalstig, E.B.4
Mincy, R.E.5
Rash, K.S.6
-
15
-
-
0033537719
-
Positive and negativeregulation of IκB kinase activity through IKKβsubunit phosphorylation
-
Delhase M, Hayakawa M, Chen Y, Karin M (1999) Positive and negativeregulation of IκB kinase activity through IKKβsubunit phosphorylation. Science 284:309-13
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
16
-
-
0033624450
-
NF-κB transcription factors: Critical regulators of hematopoiesis and neuronal survival
-
Denk A, Wirth T, Baumann B (2000) NF-κB transcription factors: critical regulators of hematopoiesis and neuronal survival. Cytokine Growth Factor Rev 11:303-20
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 303-320
-
-
Denk, A.1
Wirth, T.2
Baumann, B.3
-
17
-
-
0023444192
-
Transgenic mice with increased Cu/Zn-superoxide dismutase activity: Animal model of dosageeffects in Down syndrome
-
Epstein CJ, Avraham KB, Lovett M, Smith S, Elroy-Stein O, Rotman G et al (1987) Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosageeffects in Down syndrome. Proc Natl Acad Sci USA 84:8044-8
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 8044-8048
-
-
Epstein, C.J.1
Avraham, K.B.2
Lovett, M.3
Smith, S.4
Elroy-Stein, O.5
Rotman, G.6
-
18
-
-
0033502803
-
Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice
-
Fujimura M, Morita-Fujimura Y, Kawase M, Chan PH (1999) Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 19:495-501
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 495-501
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Kawase, M.3
Chan, P.H.4
-
20
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82:373-428
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
21
-
-
0023719854
-
The 19 S multicatalytic 'prosome' proteinase is a constitutive enzyme in HeLa cells
-
Hendil KB (1988) The 19 S multicatalytic 'prosome' proteinase is a constitutive enzyme in HeLa cells. Biochem Int 17:471-7
-
(1988)
Biochem Int
, vol.17
, pp. 471-477
-
-
Hendil, K.B.1
-
22
-
-
0042707578
-
Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-κB activation
-
Henkler F, Baumann B, Fotin-Mleczek M, Weingartner M, Schwenzer R, Peters N et al (2003) Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-κB activation. J Biol Chem 278:29216-29230
-
(2003)
J Biol Chem
, vol.278
, pp. 29216-29230
-
-
Henkler, F.1
Baumann, B.2
Fotin-Mleczek, M.3
Weingartner, M.4
Schwenzer, R.5
Peters, N.6
-
23
-
-
0035122043
-
SOD1 down-regulates NF-κB and c-myc expression in mice after transient focal cerebral ischemia
-
Huang C-Y, Fujimura M, Noshita N, Chang Y-Y, Chan PH (2001) SOD1 down-regulates NF-κB and c-myc expression in mice after transient focal cerebral ischemia. J Cereb Blood Flow Metab 21:163-73
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 163-173
-
-
Huang, C.-Y.1
Fujimura, M.2
Noshita, N.3
Chang, Y.-Y.4
Chan, P.H.5
-
24
-
-
0033502802
-
Ubiquitin stress response in postischemic hippocampal neurons under nontolerant and tolerant conditions
-
Ide T, Takada K, Qiu JH, Saito N, Kawahara N, Asai A et al (1999) Ubiquitin stress response in postischemic hippocampal neurons under nontolerant and tolerant conditions. J Cereb Blood Flow Metab 19:750-6
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 750-756
-
-
Ide, T.1
Takada, K.2
Qiu, J.H.3
Saito, N.4
Kawahara, N.5
Asai, A.6
-
25
-
-
0034617341
-
Decreased nuclear factor-κB DNA binding activity following permanent focal cerebral ischaemia in the rat
-
Irving EA, Hadingham SJ, Roberts J, Gibbons M, Chabot-Fletcher M, Roshak A et al (2000) Decreased nuclear factor-κB DNA binding activity following permanent focal cerebral ischaemia in the rat. Neurosci Lett 288:45-8
-
(2000)
Neurosci Lett
, vol.288
, pp. 45-48
-
-
Irving, E.A.1
Hadingham, S.J.2
Roberts, J.3
Gibbons, M.4
Chabot-Fletcher, M.5
Roshak, A.6
-
26
-
-
0033140347
-
Activation of NF-kappa B by reactive oxygen intermediates in the nervous system
-
Kaltschmidt B, Sparna T, Kaltschmidt C (1999) Activation of NF-kappa B by reactive oxygen intermediates in the nervous system. Antioxid Redox Signal 1:129-44
-
(1999)
Antioxid Redox Signal
, vol.1
, pp. 129-144
-
-
Kaltschmidt, B.1
Sparna, T.2
Kaltschmidt, C.3
-
27
-
-
0034680928
-
Inhibition of NF-κB activation by arsenite through reaction with a critical cysteine in the activation loop of IκB kinase
-
Kapahi P, Takahashi T, Natoli G, Adams SR, Chen Y, Tsien RY et al (2000) Inhibition of NF-κB activation by arsenite through reaction with a critical cysteine in the activation loop of IκB kinase. J Biol Chem 275:36062-6
-
(2000)
J Biol Chem
, vol.275
, pp. 36062-36066
-
-
Kapahi, P.1
Takahashi, T.2
Natoli, G.3
Adams, S.R.4
Chen, Y.5
Tsien, R.Y.6
-
28
-
-
0033600604
-
The beginning of the end: IκB kinase (IKK) and NF-κB activation
-
Karin M (1999) The beginning of the end: IκB kinase (IKK) and NF-κB activation. J Biol Chem 274:27339-42
-
(1999)
J Biol Chem
, vol.274
, pp. 27339-27342
-
-
Karin, M.1
-
29
-
-
0036009115
-
NF-κB at the crossroads of life and death
-
Karin M, Lin A (2002) NF-κB at the crossroads of life and death. Nat Immunol 3:221-7
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
30
-
-
0026345023
-
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase
-
Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH (1991) Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc Natl Acad Sci USA 88:11158-62
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11158-11162
-
-
Kinouchi, H.1
Epstein, C.J.2
Mizui, T.3
Carlson, E.4
Chen, S.F.5
Chan, P.H.6
-
31
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li Q, Verma IM (2002) NF-κB regulation in the immune system. Nat Rev Immunol 2:725-34
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
32
-
-
0035194849
-
Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice
-
Noshita N, Lewén A, Sugawara T, Chan PH (2001) Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 21:1442-50
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1442-1450
-
-
Noshita, N.1
Lewén, A.2
Sugawara, T.3
Chan, P.H.4
-
33
-
-
0034724653
-
N-acetylcysteine suppresses TNF-induced NF-κB activation through inhibition of IκB kinases
-
Oka S-i, Kamata H, Kamata K, Yagisawa H, Hirata H (2000) N-acetylcysteine suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. FEBS Lett 472:196-202
-
(2000)
FEBS Lett
, vol.472
, pp. 196-202
-
-
Oka, S.-I.1
Kamata, H.2
Kamata, K.3
Yagisawa, H.4
Hirata, H.5
-
34
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
-
Palombella VJ, Rando OJ, Goldberg AL, Maniatis T (1994) The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78:773-85
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
35
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
-
Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M et al (2000) Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase. [Letter]. Nature 403:103-8
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
-
36
-
-
0033607313
-
The NF-kappa B activation pathway: A paradigm in information transfer from membrane to nucleus
-
Rothwarf DM, Karin M (1999) The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus. Sci STKE 1999:RE1
-
(1999)
Sci STKE
, vol.1999
-
-
Rothwarf, D.M.1
Karin, M.2
-
37
-
-
0037335444
-
Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway
-
Saito A, Hayashi T, Okuno S, Ferrand-Drake M, Chan PH (2003) Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway. J Neurosci 23:1710-8
-
(2003)
J Neurosci
, vol.23
, pp. 1710-1718
-
-
Saito, A.1
Hayashi, T.2
Okuno, S.3
Ferrand-Drake, M.4
Chan, P.H.5
-
38
-
-
0029119638
-
Alteration of transcription factor binding activities in the ischemic rat-brain
-
Salminen A, Liu PK, Hsu CY (1995) Alteration of transcription factor binding activities in the ischemic rat-brain. Biochem Biophys Res Commun 212:939-44
-
(1995)
Biochem Biophys Res Commun
, vol.212
, pp. 939-944
-
-
Salminen, A.1
Liu, P.K.2
Hsu, C.Y.3
-
39
-
-
0032541652
-
Signal transduction: Docking IκB kinases
-
Scheidereit C (1998) Signal transduction: docking IκB kinases. Nature 395:225-6
-
(1998)
Nature
, vol.395
, pp. 225-226
-
-
Scheidereit, C.1
-
40
-
-
0032587072
-
NF-κB is activated and promotes cell death in focal cerebral ischemia
-
Schneider A, Martin-Villalba A, Weih F, Vogel J, Wirth T, Schwaninger M (1999) NF-κB is activated and promotes cell death in focal cerebral ischemia. Nat Med 5:554-9
-
(1999)
Nat Med
, vol.5
, pp. 554-559
-
-
Schneider, A.1
Martin-Villalba, A.2
Weih, F.3
Vogel, J.4
Wirth, T.5
Schwaninger, M.6
-
41
-
-
0034668171
-
Oxidative stress interference with the nuclear factor-κB activation pathways
-
Schoonbroodt S, Piette J (2000) Oxidative stress interference with the nuclear factor-κB activation pathways. Biochem Pharmacol 60:1075-83
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1075-1083
-
-
Schoonbroodt, S.1
Piette, J.2
-
42
-
-
0034061930
-
Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia
-
Stephenson D, Yin T, Smalstig EB, Hsu MA, Panetta J, Little S, Clemens J (2000) Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia. J Cereb Blood Flow Metab 20:592-603
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 592-603
-
-
Stephenson, D.1
Yin, T.2
Smalstig, E.B.3
Hsu, M.A.4
Panetta, J.5
Little, S.6
Clemens, J.7
-
43
-
-
0035930326
-
Blocking caspase-3-mediated proteolysis of IKKβ suppresses TNF-α-induced apoptosis
-
Tang G, Yang J, Minemoto Y, Lin A (2001) Blocking caspase-3-mediated proteolysis of IKKβ suppresses TNF-α-induced apoptosis. Mol Cell 8:1005-16
-
(2001)
Mol Cell
, vol.8
, pp. 1005-1016
-
-
Tang, G.1
Yang, J.2
Minemoto, Y.3
Lin, A.4
-
44
-
-
0031126395
-
IκB proteins: Structure, function and regulation
-
Whiteside ST, Israël A (1997) IκB proteins: structure, function and regulation. Semin Cancer Biol 8:75-82
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 75-82
-
-
Whiteside, S.T.1
Israël, A.2
-
46
-
-
0028040278
-
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
-
Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P et al (1994) Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke 25:165-70
-
(1994)
Stroke
, vol.25
, pp. 165-170
-
-
Yang, G.1
Chan, P.H.2
Chen, J.3
Carlson, E.4
Chen, S.F.5
Weinstein, P.6
-
47
-
-
0033570299
-
Lack of the p50 subunit of nuclear factor-κB increases the vulnerability of hippocampal neurons to excitotoxic injury
-
Yu Z, Zhou D, Bruce-Keller AJ, Kindy MS, Mattson MP (1999) Lack of the p50 subunit of nuclear factor-κB increases the vulnerability of hippocampal neurons to excitotoxic injury. J Neurosci 19:8856-65
-
(1999)
J Neurosci
, vol.19
, pp. 8856-8865
-
-
Yu, Z.1
Zhou, D.2
Bruce-Keller, A.J.3
Kindy, M.S.4
Mattson, M.P.5
-
48
-
-
0034486561
-
Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease
-
Yu Z, Zhou D, Cheng G, Mattson MP (2000) Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease. J Mol Neurosci 15:31-44
-
(2000)
J Mol Neurosci
, vol.15
, pp. 31-44
-
-
Yu, Z.1
Zhou, D.2
Cheng, G.3
Mattson, M.P.4
|