-
1
-
-
84862603083
-
Kynurenines in the mammalian brain: when physiology meets pathology
-
Schwarcz R., Bruno J.P., Muchowski P.J., Wu H.Q. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012; 13: 465–77.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 465-477
-
-
Schwarcz, R.1
Bruno, J.P.2
Muchowski, P.J.3
Wu, H.Q.4
-
2
-
-
84869212634
-
The kynurenine pathway in brain tumor pathogenesis
-
Adams S., Braidy N., Bessede A. et al. The kynurenine pathway in brain tumor pathogenesis. Cancer Res. 2012; 72: 5649–57.
-
(2012)
Cancer Res
, vol.72
, pp. 5649-5657
-
-
Adams, S.1
Braidy, N.2
Bessede, A.3
-
4
-
-
1642296618
-
Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro
-
Alt A., Weiss B., Ogden A.M. et al. Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro. Neuropharmacology. 2004; 46: 793–806.
-
(2004)
Neuropharmacology
, vol.46
, pp. 793-806
-
-
Alt, A.1
Weiss, B.2
Ogden, A.M.3
-
5
-
-
0022657227
-
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus
-
Ganong A.H., Cotman C.W. Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus. J Pharmacol Exp Ther. 1986; 236: 293–9.
-
(1986)
J Pharmacol Exp Ther
, vol.236
, pp. 293-299
-
-
Ganong, A.H.1
Cotman, C.W.2
-
6
-
-
0011866822
-
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex
-
Kemp J.A., Foster A.C., Leeson P.D. et al. 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci USA. 1988; 85: 6547–50.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6547-6550
-
-
Kemp, J.A.1
Foster, A.C.2
Leeson, P.D.3
-
7
-
-
0024564076
-
A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists
-
Kessler M., Terramani T., Lynch G., Baudry M. A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists. J Neurochem. 1989; 52: 1319–28.
-
(1989)
J Neurochem
, vol.52
, pp. 1319-1328
-
-
Kessler, M.1
Terramani, T.2
Lynch, G.3
Baudry, M.4
-
8
-
-
67650681778
-
Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels
-
Mok M.H., Fricker A.C., Weil A., Kew J.N. Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels. Neuropharmacology. 2009; 57: 242–9.
-
(2009)
Neuropharmacology
, vol.57
, pp. 242-249
-
-
Mok, M.H.1
Fricker, A.C.2
Weil, A.3
Kew, J.N.4
-
9
-
-
0023940516
-
Identification and quantification of kynurenic acid in human brain tissue
-
Turski W.A., Nakamura M., Todd W.P., Carpenter B.K., Whetsell W.O. Jr, Schwarcz R. Identification and quantification of kynurenic acid in human brain tissue. Brain Res. 1988; 454: 164–9.
-
(1988)
Brain Res
, vol.454
, pp. 164-169
-
-
Turski, W.A.1
Nakamura, M.2
Todd, W.P.3
Carpenter, B.K.4
Whetsell, W.O.5
Schwarcz, R.6
-
10
-
-
0023883806
-
Presence of kynurenic acid in the mammalian brain
-
Moroni F., Russi P., Lombardi G., Beni M., Carla V. Presence of kynurenic acid in the mammalian brain. J Neurochem. 1988; 51: 177–80.
-
(1988)
J Neurochem
, vol.51
, pp. 177-180
-
-
Moroni, F.1
Russi, P.2
Lombardi, G.3
Beni, M.4
Carla, V.5
-
11
-
-
0035478066
-
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications
-
Hilmas C., Pereira E.F., Alkondon M., Rassoulpour A., Schwarcz R., Albuquerque E.X. The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. J Neurosci. 2001; 21: 7463–73.
-
(2001)
J Neurosci
, vol.21
, pp. 7463-7473
-
-
Hilmas, C.1
Pereira, E.F.2
Alkondon, M.3
Rassoulpour, A.4
Schwarcz, R.5
Albuquerque, E.X.6
-
12
-
-
33746823331
-
Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35
-
Wang J., Simonavicius N., Wu X. et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006; 281: 22021–8.
-
(2006)
J Biol Chem
, vol.281
, pp. 22021-22028
-
-
Wang, J.1
Simonavicius, N.2
Wu, X.3
-
13
-
-
84875226029
-
Kynurenic acid as an antagonist of alpha7 nicotinic acetylcholine receptors in the brain: facts and challenges
-
Albuquerque E.X., Schwarcz R. Kynurenic acid as an antagonist of alpha7 nicotinic acetylcholine receptors in the brain: facts and challenges. Biochem Pharmacol. 2013; 85: 1027–32.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 1027-1032
-
-
Albuquerque, E.X.1
Schwarcz, R.2
-
14
-
-
84871920238
-
Manipulating kynurenic acid levels in the brain—on the edge between neuroprotection and cognitive dysfunction
-
Szalardy L., Zadori D., Toldi J., Fulop F., Klivenyi P., Vecsei L. Manipulating kynurenic acid levels in the brain—on the edge between neuroprotection and cognitive dysfunction. Curr Top Med Chem. 2012; 12: 1797–806.
-
(2012)
Curr Top Med Chem
, vol.12
, pp. 1797-1806
-
-
Szalardy, L.1
Zadori, D.2
Toldi, J.3
Fulop, F.4
Klivenyi, P.5
Vecsei, L.6
-
15
-
-
84857627249
-
Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery
-
Moroni F., Cozzi A., Sili M., Mannaioni G. Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery. J Neural Transm. 2012; 119: 133–9.
-
(2012)
J Neural Transm
, vol.119
, pp. 133-139
-
-
Moroni, F.1
Cozzi, A.2
Sili, M.3
Mannaioni, G.4
-
16
-
-
0033795994
-
Electrophysiological effects of exogenous and endogenous kynurenic acid in the rat brain: studies in vivo and in vitro
-
Scharfman H.E., Goodman J.H., Schwarcz R. Electrophysiological effects of exogenous and endogenous kynurenic acid in the rat brain: studies in vivo and in vitro. Amino Acids. 2000; 19: 283–97.
-
(2000)
Amino Acids
, vol.19
, pp. 283-297
-
-
Scharfman, H.E.1
Goodman, J.H.2
Schwarcz, R.3
-
17
-
-
77749242786
-
Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia
-
Wonodi I., Schwarcz R. Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia. Schizophr Bull. 2010; 36: 211–8.
-
(2010)
Schizophr Bull
, vol.36
, pp. 211-218
-
-
Wonodi, I.1
Schwarcz, R.2
-
18
-
-
67650178847
-
The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection
-
Vamos E., Pardutz A., Klivenyi P., Toldi J., Vecsei L. The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection. J Neurol Sci. 2009; 283: 21–7.
-
(2009)
J Neurol Sci
, vol.283
, pp. 21-27
-
-
Vamos, E.1
Pardutz, A.2
Klivenyi, P.3
Toldi, J.4
Vecsei, L.5
-
19
-
-
59149090373
-
Pharmacological manipulation of kynurenic Acid: potential in the treatment of psychiatric disorders
-
Erhardt S., Olsson S.K., Engberg G. Pharmacological manipulation of kynurenic Acid: potential in the treatment of psychiatric disorders. CNS Drugs. 2009; 23: 91–101.
-
(2009)
CNS Drugs
, vol.23
, pp. 91-101
-
-
Erhardt, S.1
Olsson, S.K.2
Engberg, G.3
-
21
-
-
80052389762
-
Simultaneous determination of urinary tryptophan, tryptophan-related metabolites and creatinine by high performance liquid chromatography with ultraviolet and fluorimetric detection
-
Zhao J., Chen H., Ni P. et al. Simultaneous determination of urinary tryptophan, tryptophan-related metabolites and creatinine by high performance liquid chromatography with ultraviolet and fluorimetric detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2011; 879: 2720–5.
-
(2011)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.879
, pp. 2720-2725
-
-
Zhao, J.1
Chen, H.2
Ni, P.3
-
22
-
-
59649121396
-
Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry
-
Crow B., Bishop M., Paliakov E., Norton D., George J., Bralley J.A. Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry. Biomed Chromatogr. 2008; 22: 1346–53.
-
(2008)
Biomed Chromatogr
, vol.22
, pp. 1346-1353
-
-
Crow, B.1
Bishop, M.2
Paliakov, E.3
Norton, D.4
George, J.5
Bralley, J.A.6
-
23
-
-
0032241424
-
Kynurenic acid concentration in blood and urine during normal pregnancy
-
Milart P., Sikorski R. Kynurenic acid concentration in blood and urine during normal pregnancy. Ginekol Pol. 1998; 69: 968–73.
-
(1998)
Ginekol Pol
, vol.69
, pp. 968-973
-
-
Milart, P.1
Sikorski, R.2
-
24
-
-
0031738306
-
Set-up and validation of an adsorptive stripping voltammetric method for kynurenic acid determination in human urine
-
Furlanetto S., Tognini C., Carpenedo R., La P.E., Pinzauti S. Set-up and validation of an adsorptive stripping voltammetric method for kynurenic acid determination in human urine. J Pharm Biomed Anal. 1998; 18: 67–73.
-
(1998)
J Pharm Biomed Anal
, vol.18
, pp. 67-73
-
-
Furlanetto, S.1
Tognini, C.2
Carpenedo, R.3
La, P.E.4
Pinzauti, S.5
-
25
-
-
0025066259
-
Fluorometric determination of urinary kynurenic acid by flow injection analysis equipped with a “bypass line
-
Mawatari K., Iinuma F., Watanabe M. Fluorometric determination of urinary kynurenic acid by flow injection analysis equipped with a “bypass line”. Anal Biochem. 1990; 190: 88–91.
-
(1990)
Anal Biochem
, vol.190
, pp. 88-91
-
-
Mawatari, K.1
Iinuma, F.2
Watanabe, M.3
-
26
-
-
0015077064
-
Quantitative aspects of tryptophan metabolism in humans and other species: a review
-
Leklem J.E. Quantitative aspects of tryptophan metabolism in humans and other species: a review. Am J Clin Nutr. 1971; 24: 659–72.
-
(1971)
Am J Clin Nutr
, vol.24
, pp. 659-672
-
-
Leklem, J.E.1
-
27
-
-
33644630736
-
Kynurenic acid, an endogenous constituent of rheumatoid arthritis synovial fluid, inhibits proliferation of synoviocytes in vitro
-
Parada-Turska J., Rzeski W., Zgrajka W., Majdan M., Kandefer-Szerszen M., Turski W. Kynurenic acid, an endogenous constituent of rheumatoid arthritis synovial fluid, inhibits proliferation of synoviocytes in vitro. Rheumatol Int. 2006; 26: 422–6.
-
(2006)
Rheumatol Int
, vol.26
, pp. 422-426
-
-
Parada-Turska, J.1
Rzeski, W.2
Zgrajka, W.3
Majdan, M.4
Kandefer-Szerszen, M.5
Turski, W.6
-
28
-
-
0032767811
-
Intrapartum levels of endogenous glutamate antagonist—kynurenic acid in amniotic fluid, umbilical and maternal blood
-
Milart P., Urbanska E.M., Turski W.A., Paszkowski T., Sikorski R. Intrapartum levels of endogenous glutamate antagonist—kynurenic acid in amniotic fluid, umbilical and maternal blood. Neurosci Res Com. 1999; 24: 173–8.
-
(1999)
Neurosci Res Com
, vol.24
, pp. 173-178
-
-
Milart, P.1
Urbanska, E.M.2
Turski, W.A.3
Paszkowski, T.4
Sikorski, R.5
-
29
-
-
49749111172
-
Micromolar concentration of kynurenic acid in rat small intestine
-
Kuc D., Zgrajka W., Parada-Turska J., Urbanik-Sypniewska T., Turski W.A. Micromolar concentration of kynurenic acid in rat small intestine. Amino Acids. 2008; 35: 503–5.
-
(2008)
Amino Acids
, vol.35
, pp. 503-505
-
-
Kuc, D.1
Zgrajka, W.2
Parada-Turska, J.3
Urbanik-Sypniewska, T.4
Turski, W.A.5
-
30
-
-
0037789537
-
Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in renal failure
-
Pawlak D., Tankiewicz A., Matys T., Buczko W. Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in renal failure. J Physiol Pharmacol. 2003; 54: 175–89.
-
(2003)
J Physiol Pharmacol
, vol.54
, pp. 175-189
-
-
Pawlak, D.1
Tankiewicz, A.2
Matys, T.3
Buczko, W.4
-
31
-
-
58149269608
-
Presence of kynurenic acid in food and honeybee products
-
Turski M.P., Turska M., Zgrajka W., Kuc D., Turski W.A. Presence of kynurenic acid in food and honeybee products. Amino Acids. 2009; 36: 75–80.
-
(2009)
Amino Acids
, vol.36
, pp. 75-80
-
-
Turski, M.P.1
Turska, M.2
Zgrajka, W.3
Kuc, D.4
Turski, W.A.5
-
32
-
-
84858299184
-
Potato- an important source of nutritional kynurenic acid
-
Turski M.P., Kaminski P., Zgrajka W., Turska M., Turski W.A. Potato- an important source of nutritional kynurenic acid. Plant Foods Hum Nutr. 2012; 67: 17–23.
-
(2012)
Plant Foods Hum Nutr
, vol.67
, pp. 17-23
-
-
Turski, M.P.1
Kaminski, P.2
Zgrajka, W.3
Turska, M.4
Turski, W.A.5
-
33
-
-
0024403993
-
Kynurenic acid protects against gastroduodenal ulceration in mice injected with extracts from poisonous Atlantic shellfish
-
Glavin G.B., Bose R., Pinsky C. Kynurenic acid protects against gastroduodenal ulceration in mice injected with extracts from poisonous Atlantic shellfish. Prog Neuropsychopharmacol Biol Psychiatry. 1989; 13: 569–72.
-
(1989)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.13
, pp. 569-572
-
-
Glavin, G.B.1
Bose, R.2
Pinsky, C.3
-
34
-
-
0024524160
-
Kynurenic acid attenuates experimental ulcer formation and basal gastric acid secretion in rats
-
Glavin G.B., Pinsky C. Kynurenic acid attenuates experimental ulcer formation and basal gastric acid secretion in rats. Res Commun Chem Pathol Pharmacol. 1989; 64: 111–9.
-
(1989)
Res Commun Chem Pathol Pharmacol
, vol.64
, pp. 111-119
-
-
Glavin, G.B.1
Pinsky, C.2
-
35
-
-
37249019115
-
Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs
-
Kaszaki J., Palasthy Z., Erczes D. et al. Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs. Neurogastroenterol Motil. 2008; 21: 53–62.
-
(2008)
Neurogastroenterol Motil
, vol.21
, pp. 53-62
-
-
Kaszaki, J.1
Palasthy, Z.2
Erczes, D.3
-
36
-
-
74549184438
-
N-Methyl-d-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat
-
Varga G., Erces D., Fazekas B. et al. N-Methyl-d-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat. Neurogastroenterol Motil. 2010; 22: 217–25.
-
(2010)
Neurogastroenterol Motil
, vol.22
, pp. 217-225
-
-
Varga, G.1
Erces, D.2
Fazekas, B.3
-
37
-
-
1042268012
-
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease
-
Forrest C.M., Gould S.R., Darlington L.G., Stone T.W. Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. Adv Exp Med Biol. 2003; 527: 395–400.
-
(2003)
Adv Exp Med Biol
, vol.527
, pp. 395-400
-
-
Forrest, C.M.1
Gould, S.R.2
Darlington, L.G.3
Stone, T.W.4
-
38
-
-
61849182122
-
Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort
-
Clarke G., Fitzgerald P., Cryan J.F., Cassidy E.M., Quigley E.M., Dinan T.G. Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol. 2009; 9: 6.
-
(2009)
BMC Gastroenterol
, vol.9
, pp. 6
-
-
Clarke, G.1
Fitzgerald, P.2
Cryan, J.F.3
Cassidy, E.M.4
Quigley, E.M.5
Dinan, T.G.6
-
39
-
-
78149241395
-
Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome
-
Christmas D.M., Badawy A.A., Hince D. et al. Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome. Nutr Res. 2010; 30: 678–88.
-
(2010)
Nutr Res
, vol.30
, pp. 678-688
-
-
Christmas, D.M.1
Badawy, A.A.2
Hince, D.3
-
40
-
-
79960278867
-
Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells
-
Walczak K., Browski D., Langner E. et al. Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells. Scand J Gastroenterol. 2011; 46: 903–12.
-
(2011)
Scand J Gastroenterol
, vol.46
, pp. 903-912
-
-
Walczak, K.1
Browski, D.2
Langner, E.3
-
41
-
-
84866079666
-
Kynurenic acid enhances expression of p21 Waf1/Cip1 in colon cancer HT-29 cells
-
Walczak K., Turski W.A., Rzeski W. Kynurenic acid enhances expression of p21 Waf1/Cip1 in colon cancer HT-29 cells. Pharmacol Rep. 2012; 64: 745–50.
-
(2012)
Pharmacol Rep
, vol.64
, pp. 745-750
-
-
Walczak, K.1
Turski, W.A.2
Rzeski, W.3
-
42
-
-
0035893780
-
Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase
-
Han Q., Fang J., Li J. Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. Biochem J. 2001; 360: 617–23.
-
(2001)
Biochem J
, vol.360
, pp. 617-623
-
-
Han, Q.1
Fang, J.2
Li, J.3
-
44
-
-
33746329013
-
Kynurenic acid in human saliva—does it influence oral microflora?
-
Kuc D., Rahnama M., Tomaszewski T. et al. Kynurenic acid in human saliva—does it influence oral microflora? Pharmacol Rep. 2006; 58: 393–8.
-
(2006)
Pharmacol Rep
, vol.58
, pp. 393-398
-
-
Kuc, D.1
Rahnama, M.2
Tomaszewski, T.3
-
45
-
-
67349089608
-
-
Report of a Joint WHO/FAO/UNU Expert Consultation
-
WHO. Protein and amino acid requirements in human nutrition. Report of a Joint WHO/FAO/UNU Expert Consultation. 2007; http://whqlibdoc.who.int/trs/who_trs_935_eng.pdf.
-
(2007)
Protein and amino acid requirements in human nutrition
-
-
-
46
-
-
0013620048
-
The conversion of kynurenic acid to quinaldic acid by humans and rats
-
Kaihara M., Price J.M., Takahashi H. The conversion of kynurenic acid to quinaldic acid by humans and rats. J Biol Chem. 1956; 223: 705–8.
-
(1956)
J Biol Chem
, vol.223
, pp. 705-708
-
-
Kaihara, M.1
Price, J.M.2
Takahashi, H.3
-
47
-
-
79957491683
-
Distribution, synthesis, and absorption of kynurenic acid in plants
-
Turski M.P., Turska M., Zgrajka W., Bartnik M., Kocki T., Turski W.A. Distribution, synthesis, and absorption of kynurenic acid in plants. Planta Med. 2011; 77: 858–64.
-
(2011)
Planta Med
, vol.77
, pp. 858-864
-
-
Turski, M.P.1
Turska, M.2
Zgrajka, W.3
Bartnik, M.4
Kocki, T.5
Turski, W.A.6
-
48
-
-
36849072696
-
N-methyl-D-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus
-
Luccini E., Musante V., Neri E., Raiteri M., Pittaluga A. N-methyl-D-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus. J Neurosci Res. 2007; 85: 3657–65.
-
(2007)
J Neurosci Res
, vol.85
, pp. 3657-3665
-
-
Luccini, E.1
Musante, V.2
Neri, E.3
Raiteri, M.4
Pittaluga, A.5
-
49
-
-
70249095602
-
Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases
-
Senggunprai L., Yoshinari K., Yamazoe Y. Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases. Biochem J. 2009; 422: 455–62.
-
(2009)
Biochem J
, vol.422
, pp. 455-462
-
-
Senggunprai, L.1
Yoshinari, K.2
Yamazoe, Y.3
-
50
-
-
79551688725
-
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling
-
DiNatale B.C., Murray I.A., Schroeder J.C. et al. Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicol Sci. 2010; 115: 89–97.
-
(2010)
Toxicol Sci
, vol.115
, pp. 89-97
-
-
DiNatale, B.C.1
Murray, I.A.2
Schroeder, J.C.3
-
51
-
-
77953541313
-
Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension
-
Badolo L., Rasmussen L.M., Hansen H.R., Sveigaard C. Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension. Eur J Pharm Sci. 2010; 40: 282–8.
-
(2010)
Eur J Pharm Sci
, vol.40
, pp. 282-288
-
-
Badolo, L.1
Rasmussen, L.M.2
Hansen, H.R.3
Sveigaard, C.4
-
52
-
-
0026601666
-
Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase
-
Banasik M., Komura H., Shimoyama M., Ueda K. Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase. J Biol Chem. 1992; 267: 1569–75.
-
(1992)
J Biol Chem
, vol.267
, pp. 1569-1575
-
-
Banasik, M.1
Komura, H.2
Shimoyama, M.3
Ueda, K.4
-
53
-
-
34249785650
-
Kynurenic acid as an additional endogenous anti-aggregatory factor
-
ElTahir K.E.H., Bakheet B.M. Kynurenic acid as an additional endogenous anti-aggregatory factor. Saudi Pharmaceut J. 2007; 15: 135–9.
-
(2007)
Saudi Pharmaceut J
, vol.15
, pp. 135-139
-
-
ElTahir, K.E.H.1
Bakheet, B.M.2
-
54
-
-
0028882054
-
Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor
-
Jaen J.C., Laborde E., Bucsh R.A. et al. Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor. J Med Chem. 1995; 38: 4439–45.
-
(1995)
J Med Chem
, vol.38
, pp. 4439-4445
-
-
Jaen, J.C.1
Laborde, E.2
Bucsh, R.A.3
-
55
-
-
0028903541
-
Dysfunction of brain kynurenic acid metabolism in Huntington's disease: focus on kynurenine aminotransferases
-
Jauch D., Urbanska E.M., Guidetti P. et al. Dysfunction of brain kynurenic acid metabolism in Huntington's disease: focus on kynurenine aminotransferases. J Neurol Sci. 1995; 130: 39–47.
-
(1995)
J Neurol Sci
, vol.130
, pp. 39-47
-
-
Jauch, D.1
Urbanska, E.M.2
Guidetti, P.3
-
56
-
-
0029946164
-
Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome
-
Baran H., Cairns N., Lubec B., Lubec G. Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome. Life Sci. 1996; 58: 1891–9.
-
(1996)
Life Sci
, vol.58
, pp. 1891-1899
-
-
Baran, H.1
Cairns, N.2
Lubec, B.3
Lubec, G.4
-
57
-
-
0030956088
-
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid
-
Miranda A.F., Boegman R.J., Beninger R.J., Jhamandas K. Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid. Neuroscience. 1997; 78: 967–75.
-
(1997)
Neuroscience
, vol.78
, pp. 967-975
-
-
Miranda, A.F.1
Boegman, R.J.2
Beninger, R.J.3
Jhamandas, K.4
-
58
-
-
0034884986
-
Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development
-
Cannazza G., Chiarugi A., Parenti C., Zanoli P., Baraldi M. Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development. Neurochem Res. 2001; 26: 511–4.
-
(2001)
Neurochem Res
, vol.26
, pp. 511-514
-
-
Cannazza, G.1
Chiarugi, A.2
Parenti, C.3
Zanoli, P.4
Baraldi, M.5
-
59
-
-
0035161802
-
Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons
-
Erhardt S., Oberg H., Engberg G. Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons. Naunyn Schmiedebergs Arch Pharmacol. 2001; 363: 21–7.
-
(2001)
Naunyn Schmiedebergs Arch Pharmacol
, vol.363
, pp. 21-27
-
-
Erhardt, S.1
Oberg, H.2
Engberg, G.3
-
60
-
-
0342592252
-
Increased levels of kynurenic acid in brains of genetically dystonic hamsters
-
Richter A., Loscher W., Baran H., Gramer M. Increased levels of kynurenic acid in brains of genetically dystonic hamsters. Brain Res Dev Brain Res. 1996; 92: 111–6.
-
(1996)
Brain Res Dev Brain Res
, vol.92
, pp. 111-116
-
-
Richter, A.1
Loscher, W.2
Baran, H.3
Gramer, M.4
-
61
-
-
0033136456
-
Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia
-
Salvati P., Ukmar G., Dho L. et al. Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia. Prog Neuropsychopharmacol Biol Psychiatry. 1999; 23: 741–52.
-
(1999)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.23
, pp. 741-752
-
-
Salvati, P.1
Ukmar, G.2
Dho, L.3
-
62
-
-
0037175422
-
Quantitation of tryptophan, kynurenine and kynurenic acid in human plasma by capillary liquid chromatography-electrospray ionization tandem mass spectrometry
-
Amirkhani A., Heldin E., Markides K.E., Bergquist J. Quantitation of tryptophan, kynurenine and kynurenic acid in human plasma by capillary liquid chromatography-electrospray ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002; 780: 381–7.
-
(2002)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.780
, pp. 381-387
-
-
Amirkhani, A.1
Heldin, E.2
Markides, K.E.3
Bergquist, J.4
-
63
-
-
0037844896
-
Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis
-
Ilzecka J., Kocki T., Stelmasiak Z., Turski W.A. Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis. Acta Neurol Scand. 2003; 107: 412–8.
-
(2003)
Acta Neurol Scand
, vol.107
, pp. 412-418
-
-
Ilzecka, J.1
Kocki, T.2
Stelmasiak, Z.3
Turski, W.A.4
-
64
-
-
23844467167
-
Age-related increase of kynurenic acid in human cerebrospinal fluid—IgG and beta2-microglobulin changes
-
Kepplinger B., Baran H., Kainz A., Ferraz-Leite H., Newcombe J., Kalina P. Age-related increase of kynurenic acid in human cerebrospinal fluid—IgG and beta2-microglobulin changes. Neurosignals. 2005; 14: 126–35.
-
(2005)
Neurosignals
, vol.14
, pp. 126-135
-
-
Kepplinger, B.1
Baran, H.2
Kainz, A.3
Ferraz-Leite, H.4
Newcombe, J.5
Kalina, P.6
-
65
-
-
27744509130
-
Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease
-
Hartai Z., Klivenyi P., Janaky T., Penke B., Dux L., Vecsei L. Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease. J Neurol Sci. 2005; 239: 31–5.
-
(2005)
J Neurol Sci
, vol.239
, pp. 31-35
-
-
Hartai, Z.1
Klivenyi, P.2
Janaky, T.3
Penke, B.4
Dux, L.5
Vecsei, L.6
-
66
-
-
33748647647
-
Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients
-
Urbanska E.M., Luchowski P., Luchowska E. et al. Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients. Pharmacol Rep. 2006; 58: 507–11.
-
(2006)
Pharmacol Rep
, vol.58
, pp. 507-511
-
-
Urbanska, E.M.1
Luchowski, P.2
Luchowska, E.3
-
67
-
-
0027233551
-
Intravenous administration of L-kynurenine to rhesus monkeys: effect on quinolinate and kynurenate levels in serum and cerebrospinal fluid
-
Jauch D.A., Sethy V.H., Weick B.G., Chase T.N., Schwarcz R. Intravenous administration of L-kynurenine to rhesus monkeys: effect on quinolinate and kynurenate levels in serum and cerebrospinal fluid. Neuropharmacology. 1993; 32: 467–72.
-
(1993)
Neuropharmacology
, vol.32
, pp. 467-472
-
-
Jauch, D.A.1
Sethy, V.H.2
Weick, B.G.3
Chase, T.N.4
Schwarcz, R.5
-
68
-
-
0023791093
-
Kynurenic acid is present in the rat brain and its content increases during development and aging processes
-
Moroni F., Russi P., Carla V., Lombardi G. Kynurenic acid is present in the rat brain and its content increases during development and aging processes. Neurosci Lett. 1988; 94: 145–50.
-
(1988)
Neurosci Lett
, vol.94
, pp. 145-150
-
-
Moroni, F.1
Russi, P.2
Carla, V.3
Lombardi, G.4
-
69
-
-
0025236518
-
Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection
-
Swartz K.J., Matson W.R., MacGarvey U., Ryan E.A., Beal M.F. Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection. Anal Biochem. 1990; 185: 363–76.
-
(1990)
Anal Biochem
, vol.185
, pp. 363-376
-
-
Swartz, K.J.1
Matson, W.R.2
MacGarvey, U.3
Ryan, E.A.4
Beal, M.F.5
-
70
-
-
0037020506
-
Decreased level of kynurenic acid in cerebrospinal fluid of relapsing-onset multiple sclerosis patients
-
Rejdak K., Bartosik-Psujek H., Dobosz B. et al. Decreased level of kynurenic acid in cerebrospinal fluid of relapsing-onset multiple sclerosis patients. Neurosci Lett. 2002; 331: 63–5.
-
(2002)
Neurosci Lett
, vol.331
, pp. 63-65
-
-
Rejdak, K.1
Bartosik-Psujek, H.2
Dobosz, B.3
-
72
-
-
28244440276
-
Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia
-
Nilsson L.K., Linderholm K.R., Engberg G. et al. Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia. Schizophr Res. 2005; 80: 315–22.
-
(2005)
Schizophr Res
, vol.80
, pp. 315-322
-
-
Nilsson, L.K.1
Linderholm, K.R.2
Engberg, G.3
-
73
-
-
0028783959
-
Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children
-
Yamamoto H., Murakami H., Horiguchi K., Egawa B. Studies on cerebrospinal fluid kynurenic acid concentrations in epileptic children. Brain Dev. 1995; 17: 327–9.
-
(1995)
Brain Dev
, vol.17
, pp. 327-329
-
-
Yamamoto, H.1
Murakami, H.2
Horiguchi, K.3
Egawa, B.4
-
74
-
-
70349602540
-
High concentration of kynurenic acid in bile and pancreatic juice
-
Paluszkiewicz P., Zgrajka W., Saran T. et al. High concentration of kynurenic acid in bile and pancreatic juice. Amino Acids. 2009; 37: 637–41.
-
(2009)
Amino Acids
, vol.37
, pp. 637-641
-
-
Paluszkiewicz, P.1
Zgrajka, W.2
Saran, T.3
|