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Volumn 107, Issue 6, 2003, Pages 412-418

Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis; Human; Kynurenic acid; Neurodegeneration

Indexed keywords

KYNURENIC ACID;

EID: 0037844896     PISSN: 00016314     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0404.2003.00076.x     Document Type: Article
Times cited : (61)

References (52)
  • 1
    • 0022626868 scopus 로고
    • Amyotrophic lateral sclerosis. Associated clinical disorders and immunological evaluations
    • APPEL SH, STOCKTON-APPEL V, STEWART SS, KERMAN RH. Amyotrophic lateral sclerosis. Associated clinical disorders and immunological evaluations. Arch Neurol 1986;43:234-8.
    • (1986) Arch Neurol , vol.43 , pp. 234-238
    • Appel, S.H.1    Stockton-Appel, V.2    Stewart, S.S.3    Kerman, R.H.4
  • 3
    • 0021869650 scopus 로고
    • Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders
    • SCHWARCZ R, MELDRUM B. Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders. Lancet 1985;2:140-3.
    • (1985) Lancet , vol.2 , pp. 140-143
    • Schwarcz, R.1    Meldrum, B.2
  • 4
    • 0034280120 scopus 로고    scopus 로고
    • Mechanism treatment of motoneuron degeneration in ALS: What have SOD 1 mutants told us?
    • XU Z. Mechanism and treatment of motoneuron degeneration in ALS: what have SOD 1 mutants told us? Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:225-34.
    • (2000) Amyotroph Lateral Scler Other Motor Neuron Disord , vol.1 , pp. 225-234
    • Xu, Z.1
  • 5
    • 0029732866 scopus 로고    scopus 로고
    • Excitotoxicity in ALS
    • LEIGH PN, MELDRUM BS. Excitotoxicity in ALS. Neurology 1996;47 (Suppl. 4):221-7.
    • (1996) Neurology , vol.47 , Issue.SUPPL. 4 , pp. 221-227
    • Leigh, P.N.1    Meldrum, B.S.2
  • 6
    • 0035800188 scopus 로고    scopus 로고
    • Differential expression of group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS
    • LASLO P, LIPSKI J, FUNK GD. Differential expression of group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS. Neuroreport 2001;12:1903-8.
    • (2001) Neuroreport , vol.12 , pp. 1903-1908
    • Laslo, P.1    Lipski, J.2    Funk, G.D.3
  • 7
    • 0034989861 scopus 로고    scopus 로고
    • GLUR2 AMPA receptor subunit expression in motoneurons at low and high risk for degeneration in amyotrophic lateral sclerosis
    • LASLO P, LIPSKI J, NICHOLSON LF, MILES GB, FUNK GD. GLUR2 AMPA receptor subunit expression in motoneurons at low and high risk for degeneration in amyotrophic lateral sclerosis. Exp Neurol 2001;169:461-71.
    • (2001) Exp Neurol , vol.169 , pp. 461-471
    • Laslo, P.1    Lipski, J.2    Nicholson, L.F.3    Miles, G.B.4    Funk, G.D.5
  • 8
    • 0035958752 scopus 로고    scopus 로고
    • Imunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: Upregulation in reactive astrocytes
    • ARONICA E, CATANIA MV, GEURTS J, YANKAYA B, TROOST D. Imunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes. Neuroscience 2001;105:509-20.
    • (2001) Neuroscience , vol.105 , pp. 509-520
    • Aronica, E.1    Catania, M.V.2    Geurts, J.3    Yankaya, B.4    Troost, D.5
  • 9
    • 0035924377 scopus 로고    scopus 로고
    • Differential cortico-motoneuron vulnerability after chronic mitochondrial inhibition in vitro and the role of glutamate receptors
    • VAN WESTERLAAK MG, JOOSTEN EA, GRIBNAU AA, COOLS AR, BAR PR. Differential cortico-motoneuron vulnerability after chronic mitochondrial inhibition in vitro and the role of glutamate receptors. Brain Res 2001;922:243-9.
    • (2001) Brain Res , vol.922 , pp. 243-249
    • Van Westerlaak, M.G.1    Joosten, E.A.2    Gribnau, A.A.3    Cools, A.R.4    Bar, P.R.5
  • 10
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • STONE TW. Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 1993;45:309-79.
    • (1993) Pharmacol Rev , vol.45 , pp. 309-379
    • Stone, T.W.1
  • 12
    • 0033056044 scopus 로고    scopus 로고
    • Tryptophan metabolism and brain function: Focus on kynurenine and other indole metabolites
    • MORONI F. Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites. Eur J Pharmacol 1999;375:87-100.
    • (1999) Eur J Pharmacol , vol.375 , pp. 87-100
    • Moroni, F.1
  • 13
    • 0025777901 scopus 로고
    • Comparative behavioral and pharmacological studies with centrally administered kynurenine and kynurenic acid in rats
    • VECSEI L, BEAL MF. Comparative behavioral and pharmacological studies with centrally administered kynurenine and kynurenic acid in rats. Eur J Pharmacol 1991;196:239-46.
    • (1991) Eur J Pharmacol , vol.196 , pp. 239-246
    • Vecsei, L.1    Beal, M.F.2
  • 14
    • 0034720291 scopus 로고    scopus 로고
    • Neuroprotective potency of kynurenic acid against excitotoxicity
    • URENJAK J, OBRENOVITCH TP. Neuroprotective potency of kynurenic acid against excitotoxicity. Neuroreport 2000;11:1341-4.
    • (2000) Neuroreport , vol.11 , pp. 1341-1344
    • Urenjak, J.1    Obrenovitch, T.P.2
  • 15
    • 0025215998 scopus 로고
    • Excitatory amino acid antagonists protect mice against seizures induced by bicuculline
    • TURSKI WA, URBANSKA E, DZIKI M, PARADA-TURSKA J, IKONOMIDOU C. Excitatory amino acid antagonists protect mice against seizures induced by bicuculline. Brain Res 1990;514:131-4.
    • (1990) Brain Res , vol.514 , pp. 131-134
    • Turski, W.A.1    Urbanska, E.2    Dziki, M.3    Parada-Turska, J.4    Ikonomidou, C.5
  • 16
    • 0025780993 scopus 로고
    • Systemic kainic acid administration in rats: Effects on kynurenic acid production in vitro and in vivo
    • WU HQ, TURSKI WA, UNGERSTEDT U, SCHWARCZ R. Systemic kainic acid administration in rats: effects on kynurenic acid production in vitro and in vivo. Exp Neurol 1991;113:47-52.
    • (1991) Exp Neurol , vol.113 , pp. 47-52
    • Wu, H.Q.1    Turski, W.A.2    Ungerstedt, U.3    Schwarcz, R.4
  • 18
    • 0028142392 scopus 로고
    • El Escorial Word Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis
    • BROOKS BR. El Escorial Word Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 1994;124(Suppl.):96-107.
    • (1994) J Neurol Sci , vol.124 , Issue.SUPPL. , pp. 96-107
    • Brooks, B.R.1
  • 19
    • 0031944832 scopus 로고    scopus 로고
    • An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole
    • RIVIERE M, MEININGER V, ZEISSER P, MUNSAT T. An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole. Arch Neurol 1998;55:526-8.
    • (1998) Arch Neurol , vol.55 , pp. 526-528
    • Riviere, M.1    Meininger, V.2    Zeisser, P.3    Munsat, T.4
  • 20
    • 0023810583 scopus 로고
    • Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography
    • SHIBATA K. Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography. J Chromatogr 1988;430:376-80.
    • (1988) J Chromatogr , vol.430 , pp. 376-380
    • Shibata, K.1
  • 21
    • 0026770032 scopus 로고
    • Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus
    • DU F, SCHMIDT W, OKUNO E, KIDO R, KOHLER C, SCHWARCZ R. Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus. J Comp Neurol 1992;321:477-87.
    • (1992) J Comp Neurol , vol.321 , pp. 477-487
    • Du, F.1    Schmidt, W.2    Okuno, E.3    Kido, R.4    Kohler, C.5    Schwarcz, R.6
  • 22
    • 0029812020 scopus 로고    scopus 로고
    • Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
    • SCHIFFER D, CORDERA S, CAVALLA P, MIGHELI A. Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis. J Neurol Sci 1996;139(Suppl.): 27-33.
    • (1996) J Neurol Sci , vol.139 , Issue.SUPPL. , pp. 27-33
    • Schiffer, D.1    Cordera, S.2    Cavalla, P.3    Migheli, A.4
  • 23
    • 0034773568 scopus 로고    scopus 로고
    • Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis
    • FEENEY SJ, MCKELVIE PA, AUSTIN L et al. Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis. Muscle Nerve 2001;24:1510-9.
    • (2001) Muscle Nerve , vol.24 , pp. 1510-1519
    • Feeney, S.J.1    McKelvie, P.A.2    Austin, L.3
  • 24
    • 0035189072 scopus 로고    scopus 로고
    • Transgenic SOD 1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels
    • BENDOTTI C, TORTAROLO M, SUCHAK SK et al. Transgenic SOD 1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels. J Neurochem 2001;79:737-46.
    • (2001) J Neurochem , vol.79 , pp. 737-746
    • Bendotti, C.1    Tortarolo, M.2    Suchak, S.K.3
  • 25
    • 0033058001 scopus 로고    scopus 로고
    • Kynurenine metabolism in Alzheimer's disease
    • BARAN H. JELLINGER K, DEECKE L. Kynurenine metabolism in Alzheimer's disease. J Neural Transm 1999;106:165-81.
    • (1999) J Neural Transm , vol.106 , pp. 165-181
    • Baran, H.1    Jellinger, K.2    Deecke, L.3
  • 26
    • 0029946164 scopus 로고    scopus 로고
    • Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome
    • BARAN H, CAIRNS N, LUBEC B, LUBEC G. Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome. Life Sci 1996;58:1891-9.
    • (1996) Life Sci , vol.58 , pp. 1891-1899
    • Baran, H.1    Cairns, N.2    Lubec, B.3    Lubec, G.4
  • 27
    • 0026671306 scopus 로고
    • Kynurenine pathway abnormalities in Parkinson's disease
    • OGAWA T, MATSON WR, BEAL MF et al. Kynurenine pathway abnormalities in Parkinson's disease. Neurology 1992;42:1702-6.
    • (1992) Neurology , vol.42 , pp. 1702-1706
    • Ogawa, T.1    Matson, W.R.2    Beal, M.F.3
  • 28
    • 0026554440 scopus 로고
    • Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex
    • BEAL MF, MATSON WR, STOREY E et al. Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex. J Neurol Sci 1992;108:80-7.
    • (1992) J Neurol Sci , vol.108 , pp. 80-87
    • Beal, M.F.1    Matson, W.R.2    Storey, E.3
  • 29
    • 0025161567 scopus 로고
    • Kynurenine pathway measurements in Huntington's disease striatum: Evidence for reduced formation of kynurenic acid
    • BEAL MF, MATSON WR, SWARTZ KJ, GAMACHE PH, BIRD ED. Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid. J Neurochem 1990;55:1327-39.
    • (1990) J Neurochem , vol.55 , pp. 1327-1339
    • Beal, M.F.1    Matson, W.R.2    Swartz, K.J.3    Gamache, P.H.4    Bird, E.D.5
  • 30
    • 0024538348 scopus 로고
    • Increase in kynurenic acid in Huntington's disease motor cortex
    • CONNICK JH, CARLA V, MORONI F, STONE TW. Increase in kynurenic acid in Huntington's disease motor cortex. J Neurochem 1989;52:985-7.
    • (1989) J Neurochem , vol.52 , pp. 985-987
    • Connick, J.H.1    Carla, V.2    Moroni, F.3    Stone, T.W.4
  • 31
    • 0025299819 scopus 로고
    • Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
    • ROTHSTEIN JD, TSAI G, KUNCL RW et al. Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Ann Neurol 1990;28:18-25.
    • (1990) Ann Neurol , vol.28 , pp. 18-25
    • Rothstein, J.D.1    Tsai, G.2    Kuncl, R.W.3
  • 32
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • ROTHSTEIN JD, MARTIN LJ, KUNCL RW. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 1992;326:1464-8.
    • (1992) N Engl J Med , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 33
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • ROTHSTEIN JD, VAN KAMMEN M, LEVEY AI, MARTIN LJ, KUNCL RW. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 1995;38:73-84.
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 34
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
    • LIN CL, BRISTOL LA, JIN L et al. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron 1998;20:589-602.
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.L.1    Bristol, L.A.2    Jin, L.3
  • 35
    • 0342409296 scopus 로고    scopus 로고
    • Formation of endogenous glutamatergic receptors antagonist kynurenic acid - Differences between cortical and spinal cord slices
    • URBANSKA EM, CHMIELEWSKI M, KOCKI T, TURSKI WA. Formation of endogenous glutamatergic receptors antagonist kynurenic acid - differences between cortical and spinal cord slices. Brain Res 2000;878:210-2
    • (2000) Brain Res , vol.878 , pp. 210-212
    • Urbanska, E.M.1    Chmielewski, M.2    Kocki, T.3    Turski, W.A.4
  • 36
    • 0033789838 scopus 로고    scopus 로고
    • Some metabotropic glutamate receptor ligands reduce kynurenate synthesis in rats by intracellular inhibition of kynurenine aminotransferase II
    • BATTAGLIA G, RASSOULPOUR A, WU HQ et al. Some metabotropic glutamate receptor ligands reduce kynurenate synthesis in rats by intracellular inhibition of kynurenine aminotransferase II. J Neurochem 2000;75:2051-60.
    • (2000) J Neurochem , vol.75 , pp. 2051-2060
    • Battaglia, G.1    Rassoulpour, A.2    Wu, H.Q.3
  • 37
    • 0025330797 scopus 로고
    • Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia
    • HEYES MP, LACKNER A. Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia. J Neurochem 1990;55:338-41.
    • (1990) J Neurochem , vol.55 , pp. 338-341
    • Heyes, M.P.1    Lackner, A.2
  • 38
    • 0026539659 scopus 로고
    • Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease
    • HEYES MP, SAITO K, CROWLEY JS et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain 1992;115:1249-73.
    • (1992) Brain , vol.115 , pp. 1249-1273
    • Heyes, M.P.1    Saito, K.2    Crowley, J.S.3
  • 39
    • 0026655828 scopus 로고
    • Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients
    • HEYES MP, BREW BJ, SAITO K et al. Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients. J Neuroimmunol 1992;40:71-80.
    • (1992) J Neuroimmunol , vol.40 , pp. 71-80
    • Heyes, M.P.1    Brew, B.J.2    Saito, K.3
  • 40
    • 0024994099 scopus 로고
    • IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis
    • ENGELHARDT JI, APPEL SH. IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch Neurol 1990:47:1210-6.
    • (1990) Arch Neurol , vol.47 , pp. 1210-1216
    • Engelhardt, J.I.1    Appel, S.H.2
  • 41
    • 0026473192 scopus 로고
    • Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis
    • SMITH RG, HAMILTON S, HOFMANN F et al. Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med 1992;327:1721-8.
    • (1992) N Engl J Med , vol.327 , pp. 1721-1728
    • Smith, R.G.1    Hamilton, S.2    Hofmann, F.3
  • 42
    • 0028194834 scopus 로고
    • Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line
    • SMITH RG, ALEXIANU ME, CRAWFORD G, NYORMOI O, STEFANI E, APPEL SH. Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line. Proc Natl Acad Sci USA 1994;91:3393-7.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3393-3397
    • Smith, R.G.1    Alexianu, M.E.2    Crawford, G.3    Nyormoi, O.4    Stefani, E.5    Appel, S.H.6
  • 44
    • 0032539876 scopus 로고    scopus 로고
    • Plasma levels of neuroexcitatory amino acids in patients with migraine or tension headache
    • ALAM Z, COOMBES N, WARING RH, WILLIAMS AC, STEVENTON GB. Plasma levels of neuroexcitatory amino acids in patients with migraine or tension headache. J Neurol Sci 1998;156:102-6.
    • (1998) J Neurol Sci , vol.156 , pp. 102-106
    • Alam, Z.1    Coombes, N.2    Waring, R.H.3    Williams, A.C.4    Steventon, G.B.5
  • 45
    • 0031690051 scopus 로고    scopus 로고
    • Nutritional management in amyotrophic lateral sclerosis: A worldwide perspective
    • SILANI V, KASARSKIS EJ, YANAGISAWA N. Nutritional management in amyotrophic lateral sclerosis: a worldwide perspective. J Neurol 1998;245(Suppl. 2):13-9.
    • (1998) J Neurol , vol.245 , Issue.SUPPL. 2 , pp. 13-19
    • Silani, V.1    Kasarskis, E.J.2    Yanagisawa, N.3
  • 46
    • 0028900544 scopus 로고
    • Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: Relation to clinical and biochemical variable
    • DEMITRACK MA, HEYES MP, ALTEMUS M, PIGOTT TA, GOLD PW. Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: relation to clinical and biochemical variable. Biol Psychiatry 1995;37:512-20.
    • (1995) Biol Psychiatry , vol.37 , pp. 512-520
    • Demitrack, M.A.1    Heyes, M.P.2    Altemus, M.3    Pigott, T.A.4    Gold, P.W.5
  • 47
    • 0028832802 scopus 로고
    • Cloning functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney
    • BUCHLI R, ALBERATI-GIANI D, MALHERBE P, KOHLER C, BROGER C, CESURA AM. Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney. J Biol Chem 1995;270:29330-5.
    • (1995) J Biol Chem , vol.270 , pp. 29330-29335
    • Buchli, R.1    Alberati-Giani, D.2    Malherbe, P.3    Kohler, C.4    Broger, C.5    Cesura, A.M.6
  • 48
    • 0030696296 scopus 로고    scopus 로고
    • Characterization of rat brain kynurenine aminotransferases I and II
    • GUIDETTI P, OKUNO E, SCHWARCZ R. Characterization of rat brain kynurenine aminotransferases I and II. J Neurosci Res 1997;50:457-65.
    • (1997) J Neurosci Res , vol.50 , pp. 457-465
    • Guidetti, P.1    Okuno, E.2    Schwarcz, R.3
  • 50
    • 0033928598 scopus 로고    scopus 로고
    • Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis
    • GUILLEMIN GJ, SMITH DG, KERR SJ et al. Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis. Redox Rep 2000;5:108-11.
    • (2000) Redox Rep , vol.5 , pp. 108-111
    • Guillemin, G.J.1    Smith, D.G.2    Kerr, S.J.3
  • 51
    • 0033502043 scopus 로고    scopus 로고
    • Kynurenine hydroxylase inhibitors reduce ischemic brain damage: Studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[N-4-(nitrophenyl) thiazol-2-yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia
    • COZZI A, CARPENEDO R, MORONI F. Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[N-4-(nitrophenyl) thiazol-2-yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia. J Cereb Blood Flow Metab 1999;19:771-7.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 771-777
    • Cozzi, A.1    Carpenedo, R.2    Moroni, F.3
  • 52
    • 0033136456 scopus 로고    scopus 로고
    • Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia
    • SALVATI P, UKMAR G, DHO L et al. Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia. Prog Neuropsychopharmacol Biol Psychiatry 1999;23:741-52.
    • (1999) Prog Neuropsychopharmacol Biol Psychiatry , vol.23 , pp. 741-752
    • Salvati, P.1    Ukmar, G.2    Dho, L.3


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