Analysis of the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model using 1H-NMR-based metabonomics

Journal of Ethnopharmacology

Volumn 151, Issue 2, 2014, Pages 912-920

  Zheng, Xiao Fen ^a   Tian, Jun Sheng ^a   Liu, Peng ^b   Xing, Jie ^a   Qin, Xue Mei ^a  

^a SHANXI UNIVERSITY   (China)

^b Shanxi Education College   (China)

Author keywords

Bu zhong yi qi tang; Metabonomics; Nuclear magnetic resonance (NMR); Spleen qi deficiency; Traditional Chinese medicine

Indexed keywords

BU-ZHONG-YI-QI-TANG; METABONOMICS; NUCLEAR MAGNETIC RESONANCE (NMR); SPLEEN-QI DEFICIENCY; TRADITIONAL CHINESE MEDICINE;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEDICINE, CHINESE TRADITIONAL; METABOLOMICS; MOTOR ACTIVITY; ORGAN SIZE; QI; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN;

EID: 84895074857     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.12.001     Document Type: Article

References (46)

1. A. Bansal, A. Bradley, K. Bishop, S. Kiani-Alikhan, and B. Ford Chronic fatigue syndrome, the immune system and viral infection Brain, Behav. Immun. 26 2012 24 31
2. A. Buriani, M.L. Garcia-Bermejo, E. Bosisio, Q. Xu, H. Li, X. Dong, M.S. Simmonds, M. Carrara, N. Tejedor, and J. Lucio-Cazana Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future J. Ethnopharmacol. 140 2012 535 544
3. X.Y. Chen Method and thought on establishing primarily standardized animal model of the spleen qi deficiency syndrome China J. Basic Med. Tradit. Chin. Med. 1 2003 3 4
4. M. Coen, E. Holmes, J.C. Lindon, and J.K. Nicholson NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology Chem. Res. Toxicol 21 2008 9 27
5. Y.T. Dai, Z.Y. Li, L.M. Xue, C.H. Dou, Y.Z. Zhou, L.Z Zhang, and X.M. Qin Metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stress J. Ethnopharmacol. 128 2010 482 489
6. J.L. Griffin, L.A. Walker, S. Garrod, E. Holmes, R.F. Shore, and J.K. Nicholson NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat Comp. Biochem. Physiol. Part B: Biochem. Mol. Biol. 127 2000 357 367
7. J.J. Hamann, K.M. Kelley, and L.B. Gladden Effect of epinephrine on net lactate uptake by contracting skeletal muscle J. Appl. Physiol. 91 2001 2635 2641
8. Q.H. He, H.R. Tang, P.P. Ren, X.F. Kong, G.Y. Wu, Y.L. Yin, and Y.L. Wang Dietary supplementation with i-Arginine partially counteracts serum metabonome induced by weaning stress in piglets J. Proteome Res. 10 2011 5214 5221
9. X.R. He, Y. Tian, Z.C. Zheng, J. Qian, and L. Ma Analysis of inflammatory cytokines in patients with diarrhea-predominant irritable bowel syndrome J. Mod. Clin. Med. 2 2013 180 181
10. Y.H. Hu, and J. Zhang Experimental study of effects of relieving stagnation-syndrome and invigorating spleen method on serum gastrin, urine d-xylose in insufficiency of the spleen rats J. Pediatr. Tradit. Chin. Med. 6 2010 12 16
11. T.C. Jansen, J. van Bommel, and J. Bakker Blood lactate monitoring in critically ill patients: a systematic health technology assessment Crit. Care Med. 37 2009 2827 2839
12. J.S. Jeong, B.H. Ryu, J.S. Kim, J.W. Park, W.C. Choi, and S.W. Yoon Bojungikki-tang for cancer-related fatigue: a pilot randomized clinical trial Integr. Cancer Ther. 4 2010 331 338
13. M. Jiang, C. Lu, C. Zhang, J. Yang, Y. Tan, A. Lu, and K. Chan Syndrome differentiation in modern research of traditional Chinese medicine J. Ethnopharmacol. 140 2012 634 642
14. J. Kang, S. Lee, S. Kang, H.N. Kwon, J.H. Park, S.W. Kwon, and S. Park NMR-based metabolomics approach for the differentiation of ginseng (Panax ginseng) roots from different origins Arch. Pharm. Res. 31 2008 330 336
15. B. Kubera, C. Hubold, S. Otte, A.S. Lindenberg, I. Zeiß, R. Krause, M. Steinkamp, J. Klement, S. Entringer, L. Pellerin, and A. Peters Rise in plasma lactate concentrations with psychosocial stress: a possible sign of cerebral energy demand Obes. Facts 5 2012 384 392
16. 1H-NMR metabolite fingerprinting and profiling analysis J. Agric. Food Chem. 57 2009 7513 7522
17. M.Y. Lee, I.S. Shin, W.Y. Jeon, C.S. Seo, H. Ha, J.I. Huh, and H.K. Shin Protective effect of bojungikki-tang, a traditional herbal formula, against alcohol-induced gastric injury in rats J. Ethnopharmacol. 142 2012 346 353
18. I. Les, E. Doval, R. García-Martínez, M. Planas, G. Cardenas, P. Gomez, M. Flavia, C. Jacas, B. Mínguez, M. Vergara, G. Soriano, C. Vila, R. Esteban, and J. Cordoba Effects of branched-chain amino acids supplementation in patients with cirrhosis and a previous episode of hepatic encephalopathy: a randomized study Am. J. Gastroenterol. 106 2011 1081 1088
19. P. Li, L.P. Yang, and Y.W. Gong Application of systems biology technology in research of traditional chinese medicine J. Tradit. Chin. Med. 29 2009 153 157
20. Y.Y. Li, M. Xie, Y. Chen, and H.H. Wang Study on TCM's syndrome model of GYPX established by a new compound method Chin. J. Basic Med. Tradit. Chinese Med. 12 2006 439 442
21. J. Liu, H.B. Chen, B.L. Guo, Z.Z. Zhao, Z.T. Liang, and T. Yi Study of the relationship between genetics and geography in determining the quality of astragali radix Biol. Pharm. Bull. 9 2011 1404 1412
22. C. Meyer, P. Saar, N. Soydan, M. Eckhard, R.G. Bretzel, J. Gerich, and T. Linn A potential important role of skeletal muscle in human counterregulation of hypoglycemia J. Clin. Endocrinol. Metab. 90 2005 6244 6250
23. Y. Muto, S. Sato, A. Watanabe, H. Moriwaki, K. Suzuki, A. Kato, M. Kato, T. Nakamura, K. Higuchi, S. Nishiguchi, and H. Kumada Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis Clin. Gastroenterol. Hepatol. 3 2005 705 713
24. J.K. Nicholson, and J.C. Lindon Systems biology: metabonomics Nature 455 2008 1054 1056
25. L. Pari, S. Srinivasan, and M. Saddiq Preventive effect of diosmin, a bioflavonoid, on glycoprotein changes in streptozotocin-nicotinamide-induced type 2 diabetic rats Int. J. Pharm. Sci. Res. 10 2010 89 95
26. S. Ren, H. Zhang, Y. Mu, Y.P. Mu, M.Y. Sun, and P. Liu Pharmacological effects of Astragaloside IV: a literature review J. Tradit. Chin. Med. 3 2013 413 416
27. K. Sairam, C.V. Rao, M.D. Babu, K.V. Kumar, V.K. Agrawal, and R.K. Goel Antiulcerogenic effect of methanolic extract of emblica officinalis: an experimental study J. Ethnopharmacol. 82 2002 1 9
28. J. Saric, J.V. Li, J.R. Swann, J. Utzinger, G. Calvert, J.K. Nicholson, S. Dirnhofer, M.J. Dallman, M. Bictash, and E. Holmes Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents J. Proteome Res. 9 2010 2255 2264
29. X.G. Shi, C.Y. Deng, L.X. Zhai, M.Y. Wang, and M.Y. Wu Pharmacological action of buzhong yiqi decoction and qi-strengthening and yang-elevating herbal compatibility on spleen-qi-deficiency rats J. Guangzhou Univ. Tradit. Chin. Med. 29 2012 271 274
30. 1H-NMR-based metabolomic approach for understanding the fermentation behaviors of wine yeast strains Anal. Chem. 81 2009 1137 1145
31. X.X. Sui, J.D. Yang, and B. Zhang Changes of hypoxia tolerance, exercise tolerance and pulmonary function of mice under the condition of hypoxic preconditioning Chin. J. Clin. Rehabil. 9 2005 61 63
32. H.R. Tang, and Y.L. Wang Metabonomics: a revolution in progress Prog. Biochem. Biophys. 33 2006 401 417
33. C.H.P. Van-Den-Akker, H. Schierbeek, G. Minderman, A. Vermes, E.M. Schoonderwaldt, J.J. Duvekot, A.P. Steegers Eric, and J.B. Van-Goudoever Amino acid metabolism in the human fetus at term: leucine, valine, and methionine kinetics Pediatr. Res. 70 2011 566 571
34. R.N. Vuille-Dit-Bille, R. Ha-Huy, and J.F. Stover Changes in plasma phenylalanine, isoleucine, leucine, and valine are associated with significant changes in intracranial pressure and jugular venous oxygen saturation in patients with severe traumatic brain injury Amino Acids 43 2012 1287 1296
35. X. Wang, H. Sun, A. Zhang, W. Sun, P. Wang, and Z. Wang Potential role of metabolomics apporoaches in the area of traditional chinese medicine: as pillars of the bridge between chinese and western medicine J. Pharm. Biomed. Anal. 55 2011 859 868
36. X.N. Wu Current concept of spleen-stomach theory and Spleen deficiency syndrome in TCM World J. Gastroenterol. 4 1998 2 6
37. B. Xiong, and H.N. Qian Effects of Sijunzi decoction and Yupingfeng powder on expression of janus kinase-signal transducer and activator of transcription signal pathway in the brain of spleen-deficiency model rats J. Tradit. Chin. Med. 33 2013 78 84
38. W. Xu, J. Wu, Y. An, C. Xiao, F. Hao, H. Liu, and H. Tang Streptozotocin-induced dynamic metabonomic changes in rat biofluids J. Proteome Res. 11 2012 3423 3435
39. Q. Xu, J.H. Wang, R.J. Wang, X.Q. Liu, Z.X. Chen, and Y.L. Wu Effect of buzhong yiqi decoction on gastrin receptor combination and its protective mechanism for gastric mucosa damage in spleen-deficiency rats J. Guangzhou Univ. Tradit. Chin. Med. 7 2003 393 395
40. H.T. Yao, Y.W. Chang, N. Uramaru, Y. Watanabe, S. Kitamura, Y.H. Kuo, and T.K. Yeh Effects of Bu-zhong-yi-qi-tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats J. Ethnopharmacol. 142 2012 121 128
41. Y. Yamaoka, T. Kawakita, and K. Nomoto Protective effect of a traditional Japanese medicine Hochu-ekki-to (Chinese name: Bu-zhong-yi-qi-tang) on the susceptibility against listeria monocytogenes in infant mice Int. Immunopharmacol. 9 2001 1669 1677
42. W. Yuan, J.X. Zhang, S.W. Li, and J.L. Edwards Amine metabolomics of hyperglycemia endothelial cells using capillary LC-MS with isobaric tagging J. Proteome Res. 10 2011 5242 5250
43. N. Zhao, W.D. Zhang, Y.M. Guo, H.W. Jia, Q.L. Zha, Z.L. Liu, S.J. Xu, and A.P. Lu Effects on neuroendocrinoimmune network of Lizhong Pill in the reserpine induced rats with spleen deficiency in traditional Chinese medicine J. Ethnopharmacol. 133 2011 454 459
44. 1H-NMR and UPLC-MS-based plasma metabonomic study to investigate the biochemical changes in chronic unpredictable mild stress model of depression Metabolomics 7 2011 413 423
45. X.W. Zheng, Y. Wang, and H. Song Experimental study on effect of buzhong yiqi decoction on serum gastrin in spleen-qi deficiency rats China J. Tradit. Chin. Med. Pharm. 7 2006 393 395
46. Z.J. Zou, X.G. Shi, M.J. Gong, S.M. Wang, and S.W. Liang Metabonomic study of rats with reserpine-induced spleen deficiency Tradit. Chin. Drug Res. Clin. Pharmacol. 23 2012 291 294