Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the e prostanoid 2 receptor on T cells

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 2, 2014, Pages

  Zasłona, Zbigniew ^a   Okunishi, Katsuhide ^a   Bourdonnay, Emilie ^a   Domingo Gonzalez, Racquel ^a   Moore, Bethany B ^a   Lukacs, Nicholas W ^a   Aronoff, David M ^a   Peters Golden, Marc ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

allergic sensitization; Asthma; CD4 T cells

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; INTERLEUKIN 13; MISOPROSTOL; OVALBUMIN; PROSTAGLANDIN E RECEPTOR 2; STAT6 PROTEIN;

ADOPTIVE TRANSFER; ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FLOW CYTOMETRY; GENOTYPE; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION; SENSITIZATION; SPLEEN CELL;

ALLERGIC SENSITIZATION; ASTHMA; BALF; BRONCHOALVEOLAR LAVAGE FLUID; CAMP; CD4 T CELLS; CYCLIC AMP; DC; DENDRITIC CELL; DIMETHYL SULFOXIDE; DMSO; E PROSTANOID; EP; EPAC; GUANINE NUCLEOTIDE EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP; NONSTEROIDAL ANTI-INFLAMMATORY DRUG; NSAID; OVA; OVALBUMIN; PG; PKA; PROSTAGLANDIN; PROSTAGLANDIN E(2); PROTEIN KINASE A; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; STAT; WILD-TYPE; WT;

ADOPTIVE TRANSFER; ALLERGENS; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; DINOPROSTONE; LYMPH NODES; MALE; MICE; MICE, KNOCKOUT; MISOPROSTOL; OVALBUMIN; PNEUMONIA; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SPLEEN;

EID: 84895060979     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.07.037     Document Type: Article

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