Transcriptional activation of SHP by PPAR-γ in liver

Biochemical and Biophysical Research Communications

Volumn 360, Issue 2, 2007, Pages 301-306

  Kim, Ha il ^a   Koh, Yoo Kyung ^a   Kim, Tae Hyun ^a   Kwon, Sool Ki ^a   Im, Seung Soon ^a   Choi, Hueng Sik ^b   Kim, Kyung Sup ^a   Ahn, Yong Ho ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Gluconeogenesis; PPAR ; SHP

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE FUNCTION; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; RAT;

ANIMALS; CELLS, CULTURED; HEPATOCYTES; LIVER; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; SHP1 PROTEIN TYROSINE PHOSPHATASE; TRANS-ACTIVATION (GENETICS);

RATTUS;

EID: 34447105982     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.171     Document Type: Article

References (34)

1. Hall R.K., Yamasaki T., Kucera T., Waltner-Law M., O'Brien R., and Granner D.K. Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins. J. Biol. Chem. 275 (2000) 30169-30175
2. Schmoll D., Walker K.S., Alessi D.R., Grempler R., Burchell A., Guo S., Walther R., and Unterman T.G. Regulation of glucose-6-phosphatase gene expression by protein kinase B alpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity. J. Biol. Chem. 275 (2000) 36324-36333
3. Argaud D., Zhang Q., Pan W., Maitra S., Pilkis S.J., and Lange A.J. Regulation of rat liver glucose-6-phosphatase gene expression in different nutritional and hormonal states: gene structure and 5′-flanking sequence. Diabetes 45 (1996) 1563-1571
4. Yoon J.C., Puigserver P., Chen G., Donovan J., Wu Z., Rhee J., Adelmant G., Stafford J., Kahn C.R., Granner D.K., Newgard C.B., and Spiegelman B.M. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413 (2001) 131-138
5. Rhee J., Inoue Y., Yoon J.C., Puigserver P., Fan M., Gonzalez F.J., and Spiegelman B.M. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc. Natl. Acad. Sci. USA 100 (2003) 4012-4017
6. Puigserver P., Rhee J., Donovan J., Walkey C.J., Yoon J.C., Oriente F., Kitamura Y., Altomonte J., Dong H., Accili D., and Spiegelman B.M. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423 (2003) 550-555
7. Nakae J., Biggs III W.H., Kitamura T., Cavenee W.K., Wright C.V., Arden K.C., and Accili D. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat. Genet. 32 (2002) 245-253
8. Willson T.M., Lambert M.H., and Kliewer S.A. Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu. Rev. Biochem. 70 (2001) 341-367
9. Auboeuf D., Rieusset J., Fajas L., Vallier P., Frering V., Riou J.P., Staels B., Auwerx J., Laville M., and Vidal H. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46 (1997) 1319-1327
10. Kim S.Y., Kim H.I., Park S.K., Im S.S., Li T., Cheon H.G., and Ahn Y.H. Liver glucokinase can be activated by peroxisome proliferator-activated receptor-gamma. Diabetes 53 Suppl. 1 (2004) S66-S70
11. Way J.M., Harrington W.W., Brown K.K., Gottschalk W.K., Sundseth S.S., Mansfield T.A., Ramachandran R.K., Willson T.M., and Kliewer S.A. Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues. Endocrinology 142 (2001) 1269-1277
12. Seol W., Choi H.S., and Moore D.D. An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science 272 (1996) 1336-1339
13. Goodwin B., Jones S.A., Price R.R., Watson M.A., McKee D.D., Moore L.B., Galardi C., Wilson J.G., Lewis M.C., Roth M.E., Maloney P.R., Willson T.M., and Kliewer S.A. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol. Cell 6 (2000) 517-526
14. Lu T.T., Makishima M., Repa J.J., Schoonjans K., Kerr T.A., Auwerx J., and Mangelsdorf D.J. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol. Cell 6 (2000) 507-515
15. Watanabe M., Houten S.M., Wang L., Moschetta A., Mangelsdorf D.J., Heyman R.A., Moore D.D., and Auwerx J. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J. Clin. Invest. 113 (2004) 1408-1418
16. Lee Y.K., Parker K.L., Choi H.S., and Moore D.D. Activation of the promoter of the orphan receptor SHP by orphan receptors that bind DNA as monomers. J. Biol. Chem. 274 (1999) 20869-20873
17. Shih D.Q., Screenan S., Munoz K.N., Philipson L., Pontoglio M., Yaniv M., Polonsky K.S., and Stoffel M. Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes 50 (2001) 2472-2480
18. Sanyal S., Kim J.Y., Kim H.J., Takeda J., Lee Y.K., Moore D.D., and Choi H.S. Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. J. Biol. Chem. 277 (2002) 1739-1748
19. Zhang Y., and Dufau M.L. Gene silencing by nuclear orphan receptors. Vitam. Horm. 68 (2004) 1-48
20. Lee H.K., Lee Y.K., Park S.H., Kim Y.S., Lee J.W., Kwon H.B., Soh J., Moore D.D., and Choi H.S. Structure and expression of the orphan nuclear receptor SHP gene. J. Biol. Chem. 273 (1998) 14398-14402
21. Sinal C.J., Tohkin M., Miyata M., Ward J.M., Lambert G., and Gonzalez F.J. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102 (2000) 731-744
22. Kim H.I., Kim J.W., Kim S.H., Cha J.Y., Kim K.S., and Ahn Y.H. Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter. Diabetes 49 (2000) 1517-1524
23. Kim S.Y., Kim H.I., Kim T.H., Im S.S., Park S.K., Lee I.K., Kim K.S., and Ahn Y.H. SREBP-1c mediates the insulin-dependent hepatic glucokinase expression. J. Biol. Chem. 279 (2004) 30823-30829
24. Kim H.I., Cha J.Y., Kim S.Y., Kim J.W., Roh K.J., Seong J.K., Lee N.T., Choi K.Y., Kim K.S., and Ahn Y.H. Peroxisomal proliferator-activated receptor-gamma upregulates glucokinase gene expression in beta-cells. Diabetes 51 (2002) 676-685
25. Goodwin B., Watson M.A., Kim H., Miao J., Kemper J.K., and Kliewer S.A. Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha. Mol. Endocrinol. 17 (2003) 386-394
26. Suter S.L., Nolan J.J., Wallace P., Gumbiner B., and Olefsky J.M. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care 15 (1992) 193-203
27. Fujiwara T., Yoshioka S., Yoshioka T., Ushiyama I., and Horikoshi H. Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes 37 (1988) 1549-1558
28. Tontonoz P., Hu E., Devine J., Beale E.G., and Spiegelman B.M. PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 15 (1995) 351-357
29. Davies G.F., Khandelwal R.L., and Roesler W.J. Troglitazone inhibits expression of the phosphoenolpyruvate carboxykinase gene by an insulin-independent mechanism. Biochim. Biophys. Acta 1451 (1999) 122-131
30. Glorian M., Duplus E., Beale E.G., Scott D.K., Granner D.K., and Forest C. A single element in the phosphoenolpyruvate carboxykinase gene mediates thiazolidinedione action specifically in adipocytes. Biochimie 83 (2001) 933-943
31. Lee Y.K., Dell H., Dowhan D.H., Hadzopoulou-Cladaras M., and Moore D.D. The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression. Mol. Cell. Biol. 20 (2000) 187-195
32. Borgius L.J., Steffensen K.R., Gustafsson J.A., and Treuter E. Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP. J. Biol. Chem. 277 (2002) 49761-49766
33. Wang L., Liu J., Saha P., Huang J., Chan L., Spiegelman B., and Moore D.D. The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes. Cell Metab. 2 (2005) 227-238
34. Yamagata K., Daitoku H., Shimamoto Y., Matsuzaki H., Hirota K., Ishida J., and Fukamizu A. Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1. J. Biol. Chem. 279 (2004) 23158-23165