Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcription

Diabetologia

Volumn 57, Issue 3, 2014, Pages 592-602

  Bi, Yan ^a,b   Wu, Wenjun ^b   Shi, Junfeng ^b   Liang, Hua ^c   Yin, Wenwen ^b   Chen, Yingying ^a   Tang, Sunyinyan ^a   Cao, Shu ^b   Cai, Mengyin ^c   Shen, Shanmei ^a   Gao, Qian ^a   Weng, Jianping ^c,d   Zhu, Dalong ^a,b  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d Key Laboratory of Food Safety of Guangdong Province   (China)

Author keywords

Insulin resistance; IRS 1; Skeletal muscle; SREBP 1c

Indexed keywords

ANTIDIABETIC AGENT; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; METFORMIN; SIGNAL PEPTIDE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADENOVIRIDAE; ANIMAL; CELL CULTURE; DRUG EFFECTS; INSULIN RESISTANCE; LIPID DIET; METABOLISM; PROMOTER REGION; RAT; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DIET, HIGH-FAT; HYPOGLYCEMIC AGENTS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; METFORMIN; MUSCLE, SKELETAL; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTIONAL ACTIVATION;

EID: 84894592727     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3136-1     Document Type: Article

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