Irinotecan disrupts tight junction proteins within the gut: Implications for chemotherapy-induced gut toxicity

Cancer Biology and Therapy

Volumn 15, Issue 2, 2014, Pages 236-244

  Wardill, Hannah R ^a   Bowen, Joanne M ^a   Al Dasooqi, Noor ^a   Sultani, Masooma ^a   Bateman, Emma ^a   Stansborough, Romany ^a   Shirren, Joseph ^a   Gibson, Rachel J ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Chemotherapy; Claudin 1; Gut toxicity; Mucositis; Occludin; Pro inflammatory Cytokines; Tight junctions; Zonular occludens 1

Indexed keywords

CHEMOTHERAPY; CLAUDIN-1; GUT TOXICITY; MUCOSITIS; OCCLUDIN; PRO-INFLAMMATORY CYTOKINES; TIGHT JUNCTIONS; ZONULAR-OCCLUDENS-1;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CLAUDIN-1; DIARRHEA; FEMALE; INTESTINAL MUCOSA; INTESTINE, LARGE; INTESTINE, SMALL; OCCLUDIN; RATS; TIGHT JUNCTIONS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84894548556     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.27222     Document Type: Article

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