-
1
-
-
0033551811
-
Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1: A potential mechanism for vascular permeability in diabetic retinopathy and tumors
-
Antonetti DA, Barber AJ, Hollinger LA, Wolpert EB, Gardner TW (1999) Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occludens 1. A potential mechanism for vascular permeability in diabetic retino-pathy and tumors. J Biol Chem 274:23463-23467 (Pubitemid 129529185)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.33
, pp. 23463-23467
-
-
Antonetti, D.A.1
Barber, A.J.2
Hollinger, L.A.3
Wolpert, E.B.4
Gardner, T.W.5
-
2
-
-
0035903828
-
Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia
-
Asahi M, Sumii T, Fini ME, Itohara S, Lo EH (2001a) Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia. Neuroreport 12:3003-3007 (Pubitemid 32882025)
-
(2001)
NeuroReport
, vol.12
, Issue.13
, pp. 3003-3007
-
-
Asahi, M.1
Sumii, T.2
Fini, M.E.3
Itohara, S.4
Lo, E.H.5
-
3
-
-
0035478029
-
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
-
Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, Fini ME, Lo EH (2001b) Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 21:7724-7732 (Pubitemid 32904971)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.19
, pp. 7724-7732
-
-
Asahi, M.1
Wang, X.2
Mori, T.3
Sumii, T.4
Jung, J.-C.5
Moskowitz, M.A.6
Fini, M.E.7
Lo, E.H.8
-
4
-
-
2942580900
-
The specific fates of tight junction proteins in apoptopic epithelial cells
-
DOI 10.1242/jcs.01071
-
Bojarski C, Weiske J, Schöneberg T, Schröder W, Mankertz J, Schulzke J, Florian P, Fromm M, Tauber R, Huber O (2004) The specific fates of tight junction proteins in apoptotic epithelial cells. J Cell Sci 117:2097-2107 (Pubitemid 38745142)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.10
, pp. 2097-2107
-
-
Bojarski, C.1
Weiske, J.2
Schoneberg, T.3
Schroder, W.4
Mankertz, J.5
Schulzke, J.-D.6
Florian, P.7
Fromm, M.8
Tauber, R.9
Huber, O.10
-
5
-
-
12444249974
-
Hypoxia/aglycemia alters expression of occludin and actin in brain endothelial cells
-
DOI 10.1016/j.bbrc.2004.12.123, PII S0006291X04029249
-
Brown RC, Davis TP (2005) Hypoxia/aglycemia alters expression of occludin and actin in brain endothelial cells. Biochem Biophys Res Commun 327:1114-1123 (Pubitemid 40142636)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.327
, Issue.4
, pp. 1114-1123
-
-
Brown, R.C.1
Davis, T.P.2
-
6
-
-
0037442659
-
Protection against hypoxia-induced increase in blood-brain barrier permeability: Role of tight junction proteins and NFkappaB
-
Brown RC, Mark KS, Egleton RD, Huber JD, Burroughs AR, Davis TP (2003) Protection against hypoxia-induced increase in blood-brain barrier permeability: role of tight junction proteins and NFkappaB. J Cell Sci 116:693-700
-
(2003)
J Cell Sci
, vol.116
, pp. 693-700
-
-
Brown, R.C.1
Mark, K.S.2
Egleton, R.D.3
Huber, J.D.4
Burroughs, A.R.5
Davis, T.P.6
-
7
-
-
0348141854
-
Activation Systems for Latent Matrix Metalloproteinase-2 Are Upregulated Immediately after Focal Cerebral Ischemia
-
Chang D, Hosomi N, Lucero J, Heo J, Abumiya T, Mazar AP, del Zoppo GJ (2003) Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia. J Cereb Blood Flow Metab 23:1408-1419 (Pubitemid 38018259)
-
(2003)
Journal of Cerebral Blood Flow and Metabolism
, vol.23
, Issue.12
, pp. 1408-1419
-
-
Chang, D.-I.1
Hosomi, N.2
Lucero, J.3
Heo, J.-H.4
Abumiya, T.5
Mazar, A.P.6
Del Zoppo, G.J.7
-
8
-
-
20344373695
-
Multiple roles for MMPs and TIMPs in cerebral ischemia
-
DOI 10.1002/glia.20169
-
Cunningham LA, Wetzel M, Rosenberg GA (2005) Multiple roles for MMPs and TIMPs in cerebral ischemia. Glia 50:329-339 (Pubitemid 40780839)
-
(2005)
GLIA
, vol.50
, Issue.4
, pp. 329-339
-
-
Cunningham, L.A.1
Wetzel, M.2
Rosenberg, G.A.3
-
9
-
-
1242317092
-
Simultaneous Activation of Several Second Messengers in Hypoxia-Induced Hyperpermeability of Brain Derived Endothelial Cells
-
DOI 10.1002/jcp.10417
-
Fischer S, Wiesnet M, Marti HH, Renz D, Schaper W (2004) Simultaneous activation of several second messengers in hypoxia-induced hyperpermeability of brain derived endothelial cells. J Cell Physiol 198:359-369 (Pubitemid 38235031)
-
(2004)
Journal of Cellular Physiology
, vol.198
, Issue.3
, pp. 359-369
-
-
Fischer, S.1
Wiesnet, M.2
Marti, H.H.3
Renz, D.4
Schaper, W.5
-
10
-
-
0033696031
-
Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells
-
Fischer S, Wobben M, Kleinstück J, Renz D, Schaper W (2000) Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells. Am J Physiol Cell Physiol 279:C935-44
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Fischer, S.1
Wobben, M.2
Kleinstück, J.3
Renz, D.4
Schaper, W.5
-
11
-
-
0036354737
-
Hypoxia-induced hyperpermeability in brain microvessel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1
-
DOI 10.1006/mvre.2001.2367
-
Fischer S, Wobben M, Marti HH, Renz D, Schaper W (2002) Hypoxia-induced hyperpermeability in brain microves-sel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1. Microvasc Res 63:70-80 (Pubitemid 34971510)
-
(2002)
Microvascular Research
, vol.63
, Issue.1
, pp. 70-80
-
-
Fischer, S.1
Wobben, M.2
Marti, H.H.3
Renz, D.4
Schaper, W.5
-
12
-
-
0035194622
-
Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia
-
Gasche Y, Copin JC, Sugawara T, Fujimura M, Chan PH (2001) Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. J Cereb Blood Flow Metab 21:1393-1400 (Pubitemid 33120943)
-
(2001)
Journal of Cerebral Blood Flow and Metabolism
, vol.21
, Issue.12
, pp. 1393-1400
-
-
Gasche, Y.1
Copin, J.-C.2
Sugawara, T.3
Fujimura, M.4
Chan, P.H.5
-
13
-
-
18744362465
-
Matrix metalloproteinases in early diabetic retinopathy and their role in alternation of the blood-retinal barrier
-
DOI 10.1038/labinvest.3700251
-
Giebel SJ, Menicucci G, McGuire PG, Das A (2005) Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier. Lab Invest 85:597-607 (Pubitemid 40675441)
-
(2005)
Laboratory Investigation
, vol.85
, Issue.5
, pp. 597-607
-
-
Giebel, S.J.1
Menicucci, G.2
McGuire, P.G.3
Das, A.4
-
14
-
-
30744477950
-
From angiogenesis to neuro-pathology
-
Greenberg DA, Jin K (2005) From angiogenesis to neuro-pathology. Nature 438:954-959
-
(2005)
Nature
, vol.438
, pp. 954-959
-
-
Greenberg, D.A.1
Jin, K.2
-
16
-
-
0028792449
-
Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion
-
Hamann GF, Okada Y, Fitridge R, del Zoppo GJ (1995) Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke 26:2120-2126
-
(1995)
Stroke
, vol.26
, pp. 2120-2126
-
-
Hamann, G.F.1
Okada, Y.2
Fitridge, R.3
Del Zoppo, G.J.4
-
17
-
-
22944483792
-
The blood-brain barrier/ neurovascular unit in health and disease
-
Hawkins BT, Davis TP (2005) The blood-brain barrier/ neurovascular unit in health and disease. Pharmacol Rev 57:173-185
-
(2005)
Pharmacol Rev
, vol.57
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
18
-
-
35148897176
-
Positive feedback regulation between MMP-9 and VEGF in human RPE cells
-
DOI 10.1167/iovs.06-1234
-
Hollborn M, Stathopoulos C, Steffen A, Wiedemann P, Kohen L, Bringmann A (2007) Positive feedback regulation between MMP-9 and VEGF in human RPE cells. Invest Ophthalmol Vis Sci 48:4360-4367 (Pubitemid 351261070)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.9
, pp. 4360-4367
-
-
Hollborn, M.1
Stathopoulos, C.2
Steffen, A.3
Wiedemann, P.4
Kohen, L.5
Bringmann, A.6
-
19
-
-
0037313641
-
P38 MAP kinase\a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability
-
Issbrücker K, Marti HH, Hippenstiel S, Springmann G, Voswinckel R, Gaumann A, Breier G, Drexler HCA, Suttorp N, Clauss M (2003) p38 MAP kinase\a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J 17:262-264
-
(2003)
FASEB J
, vol.17
, pp. 262-264
-
-
Issbrücker, K.1
Marti, H.H.2
Hippenstiel, S.3
Springmann, G.4
Voswinckel, R.5
Gaumann, A.6
Breier, G.7
Drexler, H.C.A.8
Suttorp, N.9
Clauss, M.10
-
20
-
-
34247522718
-
Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness
-
DOI 10.1038/sj.jcbfm.9600404, PII 9600404
-
Kallenberg K, Bailey DM, Christ S, Mohr A, Roukens R, Menold E, Steiner T, Bärtsch P, Knauth M (2007) Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness. J Cereb Blood Flow Metab 27:1064-1071 (Pubitemid 46659029)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.5
, pp. 1064-1071
-
-
Kallenberg, K.1
Bailey, D.M.2
Christ, S.3
Mohr, A.4
Roukens, R.5
Menold, E.6
Steiner, T.7
Bartsch, P.8
Knauth, M.9
-
21
-
-
33845666847
-
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia
-
DOI 10.1096/fj.05-4829fje
-
Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM (2006) The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J 20:1185-1187 (Pubitemid 44943866)
-
(2006)
FASEB Journal
, vol.20
, Issue.8
-
-
Kilic, E.1
Kilic, U.2
Wang, Y.3
Bassetti, C.L.4
Marti, H.H.5
Hermann, D.M.6
-
22
-
-
0028345645
-
Quantitative zymography: Detection of picogram quantities of gelatinases
-
DOI 10.1006/abio.1994.1186
-
Kleiner DE, Stetler-Stevenson WG (1994) Quantitative zymography: detection of picogram quantities of gelati-nases. Anal Biochem 218:325-329 (Pubitemid 24141631)
-
(1994)
Analytical Biochemistry
, vol.218
, Issue.2
, pp. 325-329
-
-
Kleiner, D.E.1
Stetlerstevenson, W.G.2
-
23
-
-
34247842900
-
Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells
-
DOI 10.2353/ajpath.2007.060693
-
Koto T, Takubo K, Ishida S, Shinoda H, Inoue M, Tsubota K, Okada Y, Ikeda E (2007) Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells. Am J Pathol 170:1389-1397 (Pubitemid 47339345)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.4
, pp. 1389-1397
-
-
Koto, T.1
Takubo, K.2
Ishida, S.3
Shinoda, H.4
Inoue, M.5
Tsubota, K.6
Okada, Y.7
Ikeda, E.8
-
24
-
-
34548204870
-
Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracerebral hemorrhage
-
DOI 10.1161/STROKEAHA.106.481515, PII 0000767020070900000029
-
Lee CZ, Xue Z, Zhu Y, Yang G, Young WL (2007) Matrix metalloproteinase-9 inhibition attenuates vascular en-dothelial growth factor-induced intracerebral hemorrhage. Stroke 38:2563-2568 (Pubitemid 47329638)
-
(2007)
Stroke
, vol.38
, Issue.9
, pp. 2563-2568
-
-
Lee, C.Z.1
Xue, Z.2
Zhu, Y.3
Yang, G.-Y.4
Young, W.L.5
-
25
-
-
58149326864
-
Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia
-
Liu W, Hendren J, Qin X, Shen J, Liu KJ (2009) Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia. J Neurochem 108:811-820
-
(2009)
J Neurochem
, vol.108
, pp. 811-820
-
-
Liu, W.1
Hendren, J.2
Qin, X.3
Shen, J.4
Liu, K.J.5
-
26
-
-
0036084919
-
Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation
-
Mark KS, Davis TP (2002) Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation. Am J Physiol Heart Circ Physiol 282:H1485-94
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Mark, K.S.1
Davis, T.P.2
-
28
-
-
67449128444
-
Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress
-
McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP (2009) Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. J Neurochem 110:58-71
-
(2009)
J Neurochem
, vol.110
, pp. 58-71
-
-
McCaffrey, G.1
Willis, C.L.2
Staatz, W.D.3
Nametz, N.4
Quigley, C.A.5
Hom, S.6
Lochhead, J.J.7
Davis, T.P.8
-
29
-
-
58249126857
-
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
-
Rosenberg GA (2009) Matrix metalloproteinases and their multiple roles in neurodegenerative diseases. Lancet Neurol 8:205-216
-
(2009)
Lancet Neurol
, vol.8
, pp. 205-216
-
-
Rosenberg, G.A.1
-
30
-
-
53749096762
-
Blood-brain barrier tight junction permeability and ischemic stroke
-
Sandoval KE, Witt KA (2008) Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiol Dis 32:200-219
-
(2008)
Neurobiol Dis
, vol.32
, pp. 200-219
-
-
Sandoval, K.E.1
Witt, K.A.2
-
31
-
-
0036846795
-
Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain
-
Schoch HJ, Fischer S, Marti HH (2002) Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain. Brain 125:2549-2557 (Pubitemid 35303512)
-
(2002)
Brain
, vol.125
, Issue.11
, pp. 2549-2557
-
-
Schoch, H.J.1
Fischer, S.2
Marti, H.H.3
-
32
-
-
27544451238
-
VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: Both effects decreased by Ang-1
-
DOI 10.1038/sj.jcbfm.9600148, PII 9600148
-
Valable S, Montaner J, Bellail A, Berezowski V, Brillault J, Cecchelli R, Divoux D, Mackenzie ET, Bernaudin M, Roussel S, Petit E (2005) VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1. J Cereb Blood Flow Metab 25:1491-1504 (Pubitemid 41541959)
-
(2005)
Journal of Cerebral Blood Flow and Metabolism
, vol.25
, Issue.11
, pp. 1491-1504
-
-
Valable, S.1
Montaner, J.2
Bellail, A.3
Berezowski, V.4
Brillault, J.5
Cecchelli, R.6
Divoux, D.7
MacKenzie, E.T.8
Bernaudin, M.9
Roussel, S.10
Petit, E.11
-
33
-
-
34249865081
-
Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway
-
DOI 10.1002/jcp.21022
-
Vogel C, Bauer A, Wiesnet M, Preissner KT, Schaper W, Marti HH, Fischer S (2007) Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway. J Cell Physiol 212:236-243 (Pubitemid 46867606)
-
(2007)
Journal of Cellular Physiology
, vol.212
, Issue.1
, pp. 236-243
-
-
Vogel, C.1
Bauer, A.2
Wiesnet, M.3
Preissner, K.T.4
Schaper, W.5
Marti, H.H.6
Fischer, S.7
-
34
-
-
0033491912
-
Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition
-
Wachtel M, Frei K, Ehler E, Fontana A, Winterhalter K, Gloor SM (1999) Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci 112(Pt 23):4347-4356 (Pubitemid 30122026)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.23
, pp. 4347-4356
-
-
Wachtel, M.1
Frei, K.2
Ehler, E.3
Fontana, A.4
Winterhalter, K.5
Gloor, S.M.6
-
35
-
-
0035021651
-
VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly
-
Wang W, Dentler WL, Borchardt RT (2001) VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly. Am J Physiol Heart Circ Physiol 280:H434-40
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Wang, W.1
Dentler, W.L.2
Borchardt, R.T.3
-
36
-
-
11244276997
-
VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
-
DOI 10.1093/brain/awh325
-
Wang Y, Kilic E, Kilic U, Weber B, Bassetti CL, Marti HH, Hermann DM (2005) VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemo-dynamic steal phenomena. Brain 128:52-63 (Pubitemid 40070520)
-
(2005)
Brain
, vol.128
, Issue.1
, pp. 52-63
-
-
Wang, Y.1
Kilic, E.2
Kilic, U.3
Weber, B.4
Bassetti, C.L.5
Marti, H.H.6
Hermann, D.M.7
-
37
-
-
0344009459
-
Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression
-
Witt KA, Mark KS, Hom S, Davis TP (2003) Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression. Am J Physiol Heart Circ Physiol 285:H2820-31
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Witt, K.A.1
Mark, K.S.2
Hom, S.3
Davis, T.P.4
-
38
-
-
33947493391
-
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
-
DOI 10.1038/sj.jcbfm.9600375, PII 9600375
-
Yang Y, Estrada EY, Thompson JF, Liu W, Rosenberg GA (2007) Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J Cereb Blood Flow Metab 27:697-709 (Pubitemid 46474608)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.4
, pp. 697-709
-
-
Yang, Y.1
Estrada, E.Y.2
Thompson, J.F.3
Liu, W.4
Rosenberg, G.A.5
-
39
-
-
34547180418
-
Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1α accumulation and VEGF expression
-
DOI 10.1124/mol.107.036418
-
Yeh W, Lu D, Lin C, Liou H, Fu W (2007) Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression. Mol Pharmacol 72:440-449 (Pubitemid 47124124)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.2
, pp. 440-449
-
-
Yeh, W.-L.1
Lu, D.-Y.2
Lin, C.-J.3
Liou, H.-C.4
Fu, W.-M.5
|