Molecular modeling evidence for His438 flip in the mechanism of butyrylcholinesterase hysteretic behavior

Journal of Molecular Neuroscience

Volumn 52, Issue 3, 2014, Pages 434-445

  Lushchekina, Sofya V ^a   Nemukhin, Alexander V ^a,b   Varfolomeev, Sergei D ^a,b   Masson, Patrick ^c,d  

^a EMANUEL INSTITUTE OF BIOCHEMICAL PHYSICS   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Cholinesterases; His438 flip; Hysteresis; Hysteretic behavior; Molecular dynamics

Indexed keywords

AMINO ACID SEQUENCE; BUTYRYLCHOLINESTERASE; CATALYTIC DOMAIN; GLYCEROL; HISTIDINE; HUMANS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SOLVENTS; WATER;

EID: 84894384168     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0178-2     Document Type: Article

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