메뉴 건너뛰기




Volumn 23, Issue 6, 2014, Pages 1492-1505

Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of duchenne muscular dystrophy

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; AUTOPHAGY; CELL PROLIFERATION; CYTOKINES; DISEASE PROGRESSION; GENE EXPRESSION REGULATION; MICE; MICE, INBRED MDX; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NF-KAPPA B; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84894371580     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt536     Document Type: Article
Times cited : (28)

References (66)
  • 1
    • 0023614271 scopus 로고
    • Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals
    • Koenig, M., Hoffman, E.P., Bertelson, C.J., Monaco, A.P., Feener, C. and Kunkel, L.M. (1987) Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell, 50, 509-517.
    • (1987) Cell , vol.50 , pp. 509-517
    • Koenig, M.1    Hoffman, E.P.2    Bertelson, C.J.3    Monaco, A.P.4    Feener, C.5    Kunkel, L.M.6
  • 2
    • 0023614188 scopus 로고
    • Dystrophin: the protein product of the Duchenne muscular dystrophy locus
    • Hoffman, E.P., Brown, R.H. Jr and Kunkel, L.M. (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell, 51, 919-928.
    • (1987) Cell , vol.51 , pp. 919-928
    • Hoffman, E.P.1    Brown Jr., R.H.2    Kunkel, L.M.3
  • 3
    • 0035190381 scopus 로고    scopus 로고
    • The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies
    • Rando, T.A. (2001) The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies. Muscle Nerve, 24, 1575-1594.
    • (2001) Muscle Nerve , vol.24 , pp. 1575-1594
    • Rando, T.A.1
  • 5
    • 0042916443 scopus 로고    scopus 로고
    • The newfrontier in muscular dystrophy research: booster genes
    • Engvall, E. and Wewer, U.M. (2003) The newfrontier in muscular dystrophy research: booster genes. FASEB J., 17, 1579-1584.
    • (2003) FASEB J. , vol.17 , pp. 1579-1584
    • Engvall, E.1    Wewer, U.M.2
  • 6
    • 0038725634 scopus 로고    scopus 로고
    • Pharmacological strategies for muscular dystrophy
    • Khurana, T.S. and Davies, K.E. (2003) Pharmacological strategies for muscular dystrophy. Nat. Rev. Drug. Discov., 2, 379-390.
    • (2003) Nat. Rev. Drug. Discov. , vol.2 , pp. 379-390
    • Khurana, T.S.1    Davies, K.E.2
  • 7
    • 20444475788 scopus 로고    scopus 로고
    • Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies
    • Chakkalakal, J.V., Thompson, J., Parks, R.J. and Jasmin, B.J. (2005) Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies. FASEB J., 19, 880-891.
    • (2005) FASEB J. , vol.19 , pp. 880-891
    • Chakkalakal, J.V.1    Thompson, J.2    Parks, R.J.3    Jasmin, B.J.4
  • 8
    • 0034883653 scopus 로고    scopus 로고
    • Do immune cells promote the pathology of dystrophin-deficient myopathies?
    • Spencer, M.J. and Tidball, J.G. (2001) Do immune cells promote the pathology of dystrophin-deficient myopathies? Neuromuscul. Disord., 11, 556-564.
    • (2001) Neuromuscul. Disord. , vol.11 , pp. 556-564
    • Spencer, M.J.1    Tidball, J.G.2
  • 10
    • 77951205104 scopus 로고    scopus 로고
    • Therapeutic targeting of signaling pathways in muscular dystrophy
    • Bhatnagar, S. and Kumar, A. (2010) Therapeutic targeting of signaling pathways in muscular dystrophy. J. Mol. Med., 88, 155-166.
    • (2010) J. Mol. Med. , vol.88 , pp. 155-166
    • Bhatnagar, S.1    Kumar, A.2
  • 11
    • 33746579821 scopus 로고    scopus 로고
    • Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch
    • Dogra, C., Changotra, H., Wergedal, J.E. and Kumar, A. (2006) Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch. J. Cell Physiol., 208, 575-585.
    • (2006) J. Cell Physiol. , vol.208 , pp. 575-585
    • Dogra, C.1    Changotra, H.2    Wergedal, J.E.3    Kumar, A.4
  • 12
    • 42149174841 scopus 로고    scopus 로고
    • Protein-DNAarray-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice
    • Dogra, C., Srivastava, D.S. and Kumar, A. (2008) Protein-DNAarray-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice. Mol. Cell Biochem., 312, 17-24.
    • (2008) Mol. Cell Biochem. , vol.312 , pp. 17-24
    • Dogra, C.1    Srivastava, D.S.2    Kumar, A.3
  • 13
    • 0037336186 scopus 로고    scopus 로고
    • Mechanical stress activates the nuclear factor-kappaBpathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy
    • Kumar, A. and Boriek, A.M. (2003) Mechanical stress activates the nuclear factor-kappaBpathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEB J., 17, 386-396.
    • (2003) FASEB J. , vol.17 , pp. 386-396
    • Kumar, A.1    Boriek, A.M.2
  • 14
    • 0347915657 scopus 로고    scopus 로고
    • Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers
    • Kumar, A., Khandelwal, N., Malya, R., Reid, M.B. and Boriek, A.M. (2004) Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers. FASEB J., 18, 102-113.
    • (2004) FASEB J. , vol.18 , pp. 102-113
    • Kumar, A.1    Khandelwal, N.2    Malya, R.3    Reid, M.B.4    Boriek, A.M.5
  • 15
    • 0037084504 scopus 로고    scopus 로고
    • AllTRAFsare not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction
    • Chung, J.Y., Park, Y.C., Ye, H. andWu, H. (2002) AllTRAFsare not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J. Cell Sci., 115, 679-688.
    • (2002) J. Cell Sci. , vol.115 , pp. 679-688
    • Chung, J.Y.1    Park, Y.C.2    Ye, H.3    Wu, H.4
  • 16
    • 84934436115 scopus 로고    scopus 로고
    • Targeting TRAfs for therapeutic intervention
    • Zapata, J.M., Lefebvre, S. and Reed, J.C. (2007) Targeting TRAfs for therapeutic intervention. Adv. Exp. Med. Biol., 597, 188-201.
    • (2007) Adv. Exp. Med. Biol. , vol.597 , pp. 188-201
    • Zapata, J.M.1    Lefebvre, S.2    Reed, J.C.3
  • 17
    • 0035475338 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factors (TRAFs)
    • Bradley, J.R. and Pober, J.S. (2001) Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene, 20, 6482-6491.
    • (2001) Oncogene , vol.20 , pp. 6482-6491
    • Bradley, J.R.1    Pober, J.S.2
  • 18
    • 84934435747 scopus 로고    scopus 로고
    • Molecular basis for the unique specificity of TRAF6
    • Chung, J.Y., Lu, M., Yin, Q., Lin, S.C. andWu, H. (2007) Molecular basis for the unique specificity of TRAF6. Adv. Exp. Med. Biol., 597, 122-130.
    • (2007) Adv. Exp. Med. Biol. , vol.597 , pp. 122-130
    • Chung, J.Y.1    Lu, M.2    Yin, Q.3    Lin, S.C.4    Wu, H.5
  • 19
    • 33846692198 scopus 로고    scopus 로고
    • Signal integration and diversification through the p62 scaffold protein
    • Moscat, J., Diaz-Meco, M.T. and Wooten, M.W. (2007) Signal integration and diversification through the p62 scaffold protein. Trends Biochem. Sci., 32, 95-100.
    • (2007) Trends Biochem. Sci. , vol.32 , pp. 95-100
    • Moscat, J.1    Diaz-Meco, M.T.2    Wooten, M.W.3
  • 20
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen, Z.J. (2005) Ubiquitin signalling in the NF-kappaB pathway. Nat. Cell Biol., 7, 758-765.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 21
    • 67650744586 scopus 로고    scopus 로고
    • The role of ubiquitin in NF-kappaB regulatory pathways
    • Skaug, B., Jiang, X. and Chen, Z.J. (2009) The role of ubiquitin in NF-kappaB regulatory pathways. Annu. Rev. Biochem., 78, 769-796.
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 769-796
    • Skaug, B.1    Jiang, X.2    Chen, Z.J.3
  • 23
    • 76249090326 scopus 로고    scopus 로고
    • PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation
    • Nakamura, K., Kimple, A.J., Siderovski, D.P. and Johnson, G.L. (2010) PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation. J. Biol. Chem., 285, 2077-2089.
    • (2010) J. Biol. Chem. , vol.285 , pp. 2077-2089
    • Nakamura, K.1    Kimple, A.J.2    Siderovski, D.P.3    Johnson, G.L.4
  • 24
    • 4444220680 scopus 로고    scopus 로고
    • Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
    • Seibenhener, M.L., Babu, J.R., Geetha, T., Wong, H.C., Krishna, N.R. and Wooten, M.W. (2004) Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol. Cell Biol., 24, 8055-8068.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 8055-8068
    • Seibenhener, M.L.1    Babu, J.R.2    Geetha, T.3    Wong, H.C.4    Krishna, N.R.5    Wooten, M.W.6
  • 25
    • 27444433045 scopus 로고    scopus 로고
    • The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination
    • Wooten, M.W., Geetha, T., Seibenhener, M.L., Babu, J.R., Diaz-Meco, M.T. and Moscat, J. (2005) The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination. J. Biol. Chem., 280, 35625-35629.
    • (2005) J. Biol. Chem. , vol.280 , pp. 35625-35629
    • Wooten, M.W.1    Geetha, T.2    Seibenhener, M.L.3    Babu, J.R.4    Diaz-Meco, M.T.5    Moscat, J.6
  • 26
    • 77953858790 scopus 로고    scopus 로고
    • TRAF6 And A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
    • Shi, C.S. and Kehrl, J.H. (2010) TRAF6 And A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci. Signal, 3, ra42.
    • (2010) Sci. Signal , vol.3
    • Shi, C.S.1    Kehrl, J.H.2
  • 27
    • 84871856349 scopus 로고    scopus 로고
    • Reciprocal interaction between TRAF6 and notch signaling regulates adult myofiber regeneration upon injury
    • Hindi, S.M., Paul, P.K., Dahiya, S., Mishra, V., Bhatnagar, S., Kuang, S., Choi, Y. and Kumar, A. (2012) Reciprocal interaction between TRAF6 and notch signaling regulates adult myofiber regeneration upon injury. Mol. Cell Biol., 32, 4833-4845.
    • (2012) Mol. Cell Biol. , vol.32 , pp. 4833-4845
    • Hindi, S.M.1    Paul, P.K.2    Dahiya, S.3    Mishra, V.4    Bhatnagar, S.5    Kuang, S.6    Choi, Y.7    Kumar, A.8
  • 28
    • 84859951800 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms
    • Paul, P.K., Bhatnagar, S., Mishra, V., Srivastava, S., Darnay, B.G., Choi, Y. and Kumar, A. (2012) The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms. Mol. Cell Biol., 32, 1248-1259.
    • (2012) Mol. Cell Biol. , vol.32 , pp. 1248-1259
    • Paul, P.K.1    Bhatnagar, S.2    Mishra, V.3    Srivastava, S.4    Darnay, B.G.5    Choi, Y.6    Kumar, A.7
  • 30
    • 77950479450 scopus 로고    scopus 로고
    • Autophagyinskeletal muscle
    • Sandri, M. (2010)Autophagyinskeletalmuscle. FEBSLett., 584, 1411-1416.
    • (2010) FEBS Lett. , vol.584 , pp. 1411-1416
    • Sandri, M.1
  • 34
    • 36448968532 scopus 로고    scopus 로고
    • Foxo3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
    • Zhao, J., Brault, J.J., Schild, A., Cao, P., Sandri, M., Schiaffino, S., Lecker, S.H. and Goldberg, A.L. (2007) Foxo3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab., 6, 472-483.
    • (2007) Cell Metab. , vol.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6    Lecker, S.H.7    Goldberg, A.L.8
  • 38
    • 0021713536 scopus 로고
    • Muscle development inmdxmutant mice
    • Dangain, J. and Vrbova, G. (1984) Muscle development inmdxmutant mice. Muscle Nerve, 7, 700-704.
    • (1984) Muscle Nerve , vol.7 , pp. 700-704
    • Dangain, J.1    Vrbova, G.2
  • 39
    • 0026038987 scopus 로고
    • Fiber regeneration is not persistent in dystrophic (MDX) mouse skeletal muscle
    • Dimario, J.X., Uzman, A. and Strohman, R.C. (1991) Fiber regeneration is not persistent in dystrophic (MDX) mouse skeletal muscle. Dev. Biol., 148, 314-321.
    • (1991) Dev. Biol. , vol.148 , pp. 314-321
    • Dimario, J.X.1    Uzman, A.2    Strohman, R.C.3
  • 40
    • 33947506493 scopus 로고    scopus 로고
    • Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
    • Lamothe, B., Besse, A., Campos, A.D., Webster, W.K., Wu, H. and Darnay, B.G. (2007) Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J. Biol. Chem., 282, 4102-4112.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4102-4112
    • Lamothe, B.1    Besse, A.2    Campos, A.D.3    Webster, W.K.4    Wu, H.5    Darnay, B.G.6
  • 42
    • 27544457274 scopus 로고    scopus 로고
    • Damage and inflammation in muscular dystrophy: potential implications and relationships with autoimmune myositis
    • Tidball, J.G. and Wehling-Henricks, M.(2005)Damageandinflammation in muscular dystrophy: potential implications and relationships with autoimmune myositis. Curr. Opin. Rheumatol., 17, 707-713.
    • (2005) Curr. Opin. Rheumatol. , vol.17 , pp. 707-713
    • Tidball, J.G.1    Wehling-Henricks, M.2
  • 43
    • 3843052483 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: its role in health and disease
    • Kumar, A., Takada, Y., Boriek, A.M. and Aggarwal, B.B. (2004) Nuclear factor-kappaB: its role in health and disease. J. Mol. Med., 82, 434-448.
    • (2004) J. Mol. Med. , vol.82 , pp. 434-448
    • Kumar, A.1    Takada, Y.2    Boriek, A.M.3    Aggarwal, B.B.4
  • 44
    • 52549133171 scopus 로고    scopus 로고
    • Nuclear factor-kappa B signaling in skeletal muscle atrophy
    • Li, H., Malhotra, S. and Kumar, A. (2008) Nuclear factor-kappa B signaling in skeletal muscle atrophy. J. Mol. Med., 86, 1113-1126.
    • (2008) J. Mol. Med. , vol.86 , pp. 1113-1126
    • Li, H.1    Malhotra, S.2    Kumar, A.3
  • 45
    • 79957511355 scopus 로고    scopus 로고
    • NF-kappaB signaling in skeletal muscle health and disease
    • Peterson, J.M., Bakkar, N. and Guttridge, D.C. (2011) NF-kappaB signaling in skeletal muscle health and disease. Curr. Top. Dev. Biol., 96, 85-119.
    • (2011) Curr. Top. Dev. Biol. , vol.96 , pp. 85-119
    • Peterson, J.M.1    Bakkar, N.2    Guttridge, D.C.3
  • 47
    • 29944440269 scopus 로고    scopus 로고
    • Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis
    • Kuang, S., Charge, S.B., Seale, P., Huh, M. and Rudnicki, M.A. (2006) Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis. J. Cell Biol., 172, 103-113.
    • (2006) J. Cell Biol. , vol.172 , pp. 103-113
    • Kuang, S.1    Charge, S.B.2    Seale, P.3    Huh, M.4    Rudnicki, M.A.5
  • 48
    • 37548999686 scopus 로고    scopus 로고
    • Niche regulation of muscle satellite cell self-renewal and differentiation
    • Kuang, S., Gillespie, M.A. and Rudnicki, M.A. (2008) Niche regulation of muscle satellite cell self-renewal and differentiation. Cell Stem Cell, 2, 22-31.
    • (2008) Cell Stem Cell , vol.2 , pp. 22-31
    • Kuang, S.1    Gillespie, M.A.2    Rudnicki, M.A.3
  • 49
    • 34249108083 scopus 로고    scopus 로고
    • A symmetric self-renewal and commitment of satellite stem cells in muscle
    • Kuang, S., Kuroda, K., Le Grand, F. and Rudnicki, M.A. (2007)Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell, 129, 999-1010.
    • (2007) Cell , vol.129 , pp. 999-1010
    • Kuang, S.1    Kuroda, K.2    Le Grand, F.3    Rudnicki, M.A.4
  • 51
    • 0029153067 scopus 로고
    • Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine
    • Bernasconi, P., Torchiana, E., Confalonieri, P., Brugnoni, R., Barresi, R., Mora, M., Cornelio, F., Morandi, L. and Mantegazza, R. (1995) Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine. J. Clin. Invest., 96, 1137-1144.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1137-1144
    • Bernasconi, P.1    Torchiana, E.2    Confalonieri, P.3    Brugnoni, R.4    Barresi, R.5    Mora, M.6    Cornelio, F.7    Morandi, L.8    Mantegazza, R.9
  • 52
    • 33745856252 scopus 로고    scopus 로고
    • Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway
    • Peter, A.K. and Crosbie, R.H. (2006) Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway. Exp. Cell Res., 312, 2580-2591.
    • (2006) Exp. Cell Res. , vol.312 , pp. 2580-2591
    • Peter, A.K.1    Crosbie, R.H.2
  • 54
    • 0347989458 scopus 로고    scopus 로고
    • Cellular and molecular regulation of muscle regeneration
    • Charge, S.B. and Rudnicki, M.A. (2004) Cellular and molecular regulation of muscle regeneration. Physiol. Rev., 84, 209-238.
    • (2004) Physiol. Rev. , vol.84 , pp. 209-238
    • Charge, S.B.1    Rudnicki, M.A.2
  • 55
    • 37549054341 scopus 로고    scopus 로고
    • The emerging biology of satellite cells and their therapeutic potential
    • Kuang, S. and Rudnicki, M.A. (2008) The emerging biology of satellite cells and their therapeutic potential. Trends Mol. Med., 14, 82-91.
    • (2008) Trends Mol. Med. , vol.14 , pp. 82-91
    • Kuang, S.1    Rudnicki, M.A.2
  • 56
    • 0035020963 scopus 로고    scopus 로고
    • Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB
    • Langen, R.C., Schols, A.M., Kelders, M.C., Wouters, E.F. and Janssen-Heininger, Y.M. (2001) Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB. FASEB J., 15, 1169-1180.
    • (2001) FASEB J. , vol.15 , pp. 1169-1180
    • Langen, R.C.1    Schols, A.M.2    Kelders, M.C.3    Wouters, E.F.4    Janssen-Heininger, Y.M.5
  • 58
    • 0034730251 scopus 로고    scopus 로고
    • NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia
    • Guttridge, D.C., Mayo, M.W., Madrid, L.V., Wang, C.Y. and Baldwin, A.S. Jr (2000) NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. Science, 289, 2363-2366.
    • (2000) Science , vol.289 , pp. 2363-2366
    • Guttridge, D.C.1    Mayo, M.W.2    Madrid, L.V.3    Wang, C.Y.4    Baldwin Jr., A.S.5
  • 59
    • 53949103308 scopus 로고    scopus 로고
    • Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention
    • Peterson, J.M. and Guttridge, D.C. (2008) Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention. Int. Rev. Immunol., 27, 375-387.
    • (2008) Int. Rev. Immunol. , vol.27 , pp. 375-387
    • Peterson, J.M.1    Guttridge, D.C.2
  • 60
    • 33744542153 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein
    • Dogra, C., Changotra, H., Mohan, S. and Kumar, A. (2006) Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein. J. Biol. Chem., 281, 10327-10336.
    • (2006) J. Biol. Chem. , vol.281 , pp. 10327-10336
    • Dogra, C.1    Changotra, H.2    Mohan, S.3    Kumar, A.4
  • 61
    • 84872094183 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of muscle atrophy
    • Bonaldo, P. and Sandri, M. (2013) Cellular and molecular mechanisms of muscle atrophy. Dis. Model Mech., 6, 25-39.
    • (2013) Dis. Model Mech. , vol.6 , pp. 25-39
    • Bonaldo, P.1    Sandri, M.2
  • 63
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning, B.D. and Cantley, L.C. (2007) AKT/PKB signaling: navigating downstream. Cell, 129, 1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 64
    • 79952603226 scopus 로고    scopus 로고
    • Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice
    • Kim, M.H., Kay, D.I., Rudra, R.T., Chen, B.M., Hsu, N., Izumiya, Y., Martinez, L., Spencer, M.J., Walsh, K., Grinnell, A.D. et al. (2011) Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice. Hum. Mol. Genet., 20, 1324-1338.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1324-1338
    • Kim, M.H.1    Kay, D.I.2    Rudra, R.T.3    Chen, B.M.4    Hsu, N.5    Izumiya, Y.6    Martinez, L.7    Spencer, M.J.8    Walsh, K.9    Grinnell, A.D.10
  • 65
    • 84885769731 scopus 로고    scopus 로고
    • Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A
    • Yamauchi, J., Kumar, A., Duarte, L., Mehuron, T. and Girgenrath, M.(2013) Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A. Hum. Mol. Genet., 22, 4306-4317.
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 4306-4317
    • Yamauchi, J.1    Kumar, A.2    Duarte, L.3    Mehuron, T.4    Girgenrath, M.5
  • 66
    • 36849092777 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway
    • Srivastava, A.K., Qin, X., Wedhas, N., Arnush, M., Linkhart, T.A., Chadwick, R.B. and Kumar, A. (2007) Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway. J. Biol. Chem., 282, 35113-35124.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35113-35124
    • Srivastava, A.K.1    Qin, X.2    Wedhas, N.3    Arnush, M.4    Linkhart, T.A.5    Chadwick, R.B.6    Kumar, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.