LIM-homeobox gene 2 promotes tumor growth and metastasis by inducing autocrine and paracrine PDGF-B signaling

Molecular Oncology

Volumn 8, Issue 2, 2014, Pages 401-416

  Kuzmanov, Aleksandar ^a   Hopfer, Ulrike ^a,b   Marti, Patricia ^a,b   Meyer Schaller, Nathalie ^a   Yilmaz, Mahmut ^a,b   Christofori, Gerhard ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b NONE

Author keywords

EMT; Lhx2; Metastasis; PDGF B; Tumor progression

Indexed keywords

IMATINIB; LECTIN; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; UVOMORULIN; VASCULOTROPIN A; VIMENTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LHX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOCRINE EFFECT; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CANCER INCIDENCE; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISTANT METASTASIS; DISTANT METASTASIS FREE SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOTYPE; IN VITRO STUDY; LIM HOMEOBOX GENE 2; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; OVERALL SURVIVAL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR GENE; TUMOR GROWTH; TUMOR INVASION; ANIMAL MODEL; CELL INVASION; INSULINOMA; PERICYTE; TUMOR CELL;

MUS MUSCULUS;

EMT; LHX2; METASTASIS; PDGF-B; TUMOR PROGRESSION;

ANIMALS; AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; LIM-HOMEODOMAIN PROTEINS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PARACRINE COMMUNICATION; PROTO-ONCOGENE PROTEINS C-SIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84894353590     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2013.12.009     Document Type: Article

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