PDGF-BB increases endothelial migration and cord movements during angiogenesis in vitro

Journal of Cellular Biochemistry

Volumn 64, Issue 3, 1997, Pages 403-413

  Thommen, Regula ^a   Humar, Rok ^a   Misevic, Gradimir ^a   Pepper, Michael S ^b   Hahn, Alfred W A ^a   John, Margret ^a   Battegay, Edouard J ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

angiogenesis; cell migration; endothelial cell; endothelium; in vitro; PDGF; PDGF receptor; urokinase type plasminogen activator

Indexed keywords

ACTIN; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TUBULIN; UROKINASE;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIUM CELL; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ADULT; ANIMALS; BLOTTING, NORTHERN; CATTLE; CELL CULTURE TECHNIQUES; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; FACTOR ANALYSIS, STATISTICAL; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA; BOVINAE;

EID: 0031018628     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19970301)64:3<403::AID-JCB7>3.0.CO;2-Z     Document Type: Article

References (41)

1. Bacharach E, Itin A, Keshet E (1992) In vivo patterns of expression of urokinase and its inhibitor PAI-1 suggest a concerted role in regulating physiological angiogenesis. Proc Natl Acad Sci USA 89:10686-10690.
2. Bar RS, Boes M, Booth BA, Dake BL, Henley S, Hart MN (1989) The effects of platelet-derived growth factor in cultured microvessel endothelial cells. Endocrinology 124: 1841-1848.
3. Battegay EJ (1995) Angiogenesis: Mechanistic insights, neovascular diseases, and therapeutic prospects. J Mol Med 73:333-346.
4. Battegay EJ, Rupp J, Iruela-Arispe L, Sage EH, Pech M (1994) PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF β-receptors. J Cell Biol 125:917-928.
5. Battegay EJ, Thommen R, Humar R (1996) Plateletderived growth factor and angiogenesis. TIGG 8:231-251.
6. Beitz JG, Kim IS, Calabresi P, Frackelton ARJ (1991) Human microvascular endothelial cells express receptors for platelet-derived growth factor. Proc Natl Acad Sci USA 88:2021-2025.
7. Brown DM, Hong SP, Farrell CL, Pierce GF, Khouri RK (1995) Platelet-derived growth factor BB induces functional vascular anastomoses in vivo. Proc Natl Acad Sci USA 92:5920-5924.
8. Chomczynski P, Sacchi N (1987) Single step method of RNA isolation by acid quanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
9. Christ G, Seiffert D, Hufnagl P, Gessl A, Wojta J, Binder BR (1993) Type 1 plasminogen activator inhibitor synthesis of endothelial cells is downregulated by smooth muscle cells. Blood 81:1277-1283.
10. Cotta-Perreira G, Sage H, Bornstein P, Ross R, Schwartz S (1980) Studies of morphologically atypical ("sprouting") cultures of bovine aortic endothelial cells. Growth characteristics and connective tissue protein synthesis. J Cell Physiol 102:183-191.
11. Ettenson DS, Gotlieb AI (1992) Centrosomes, microtubules, and microfilaments in the reendothelialization and remodeling of double-sided in vitro wounds. Lab Invest 66:722-733.
12. Ettenson DS, Gotlieb AI (1993) In vitro large-wound reendothelialization. Inhibition of centrosome redistribution by transient inhibition of transcription after wounding prevents rapid repair. Arterioscler Thromb 13:1270-1281.
13. Ferns GA, Sprugel KH, Seifert RA, Bowen-Pope DF, Kelly JD, Murray M, Raines EW, Ross R (1990) Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF. Growth Factors 3:315-324.
14. Folkman J, Shing Y (1992) Angiogenesis. J Biol Chem 267:10931-10934.
15. Forsberg K, Valyi-Nagy I, Heldin CH, Herlyn M, Wester-mark B (1993) Platelet-derived growth factor (PDGF) in oncogenesis: Development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB. Proc Natl Acad Sci USA 90:393-397.
16. Gottlieb AI, Langille BL, Wong MKK, Kim DW (1991) Biology of disease: Structure and function of the endothelial cytoskeleton. Lab Invest 65:123-137.
17. Herren B, Rooney B, Weyer KA, Iberg N, Schmid G, Pech M (1993) Dimerization of extracellular domains of platelet-derived growth factor receptors. A revised model of receptor-ligand interaction. J Biol Chem 268:15088-15095.
18. Holmgren L, Glaser A, Pfeifer-Ohlsson S, Ohlsson R (1991) Anigogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression. Development 113:749-754.
19. Iruela-Arispe ML, Hasselaar P, Sage H (1991) Differential expression of extracellular proteins is correlated with angiogenesis in vitro. Lab Invest 64:174-186.
20. Khouri RK, Hong SP, Deune EG, Tarpley JE, Song SZ, Serdar CM, Pierce GF (1994) De novo generation of permanent neovascularized soft tissue appendages by platelet-derived growth factor. J Clin Invest 94:1757-1763.
21. Klagsbrun M, Folkman J (1990) Angiogenesis. In: Sporn MB, Roberts AB (eds): "Peptide Growth Factors and Their Receptors, II." Berlin: Springer Verlag, pp 549-574.
22. Koyama N, Hart CE, Clowes AW (1994a) Different functions of the platelet-derived growth factor-α and -β receptors for the migration and proliferation of cultured baboon smooth muscle cells. Circ Res 75:682-691.
23. Koyama N, Watanabe S, Tezuka M, Morisaki N, Saito Y, Yoshida S (1994b) Migratory and proliferative effect of platelet-derived growth factor in rabbit retinal endothelial cells: Evidence of an autocrine pathway of platelet-derived growth factor. J Cell Physiol 158:1-6.
24. Marx M, Perimutter RA, Madri JA (1994) Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis. J Clin Invest 93:131-139.
25. Menashi S, Lu H, Soria C, Legrand Y (1993) Endothelial cell proteases: Physiological role and regulation. Baillieres Clin Haematol 6:559-576.
26. Pauly RR, Bilato C, Sollott SJ, Monticone R, Kelly PT, Lakatta EG, Crow MT (1995) Role of calcium/calmodulin-dependent protein kinase II in the regulation of vascular smooth muscle cell migration. Circulation 91:1107-1115.
27. Pepper MS, Sappino AP, Stocklin R, Montesano R, Orci L, Vassalli JD (1993) Upregulation of urokinase receptor expression on migrating endothelial cells. J Cell Biol 122:673-684.
28. Pepper MS, Mandriota S, Vassalli JD, Orci L, Montesano R (1996a) Angiogenesis regulating cytokines: Activities and interactions. Curr Top Microbiol Immunol 213:31-67.
29. Pepper MS, Montesano R, Orci L, Vassalli JD (1996b) Angiogenesis: A paradigm for balanced extracellular proteolysis during cell migration and morphogenesis. Enzyme Protein 49:138-162.
30. Pierce GF, Tarpley JE, Yanagihara D, Mustoe TA, Fox GM, Thomason A (1992) Platelet-derived growth factor (BB homodimer), transforming growth factor-β 1, and basic fibroblast growth factor in dermal wound healing. Neovessel and matrix formation and cessation of repair. Am J Pathol 140:1375-1388.
31. Plate KH, Breier G, Farrell CL, Risau W (1992) Platelet-derived growth factor receptor-β is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas. Lab Invest 67:529-534.
32. Reuterdahl C, Sundberg C, Rubin K, Funa K, Gerdin B (1993) Tissue localization of β receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans. J Clin Invest 91:2065-2075.
33. Risau W (1990) Angiogenic growth factors. Prog Growth Fact Res 2:71-79.
34. Risau W, Drexler H, Mironov V, Smits A, Siegbahn A, Funa K, Heldin C (1992) Platelet-derived growth factor is angiogenic in vivo. Growth Factors 7:261-266.
35. Ross R (1993) The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362:801-809.
36. Sato N, Beitz JG, Kato J, Yamamoto M, Clark JW, Calabresi P, Frackelton AR Jr (1993) Platelet-derived growth factor indirectly stimulates angiogenesis in vitro. Am J Pathol 142:1119-1130.
37. Siegbahn A, Hammacher A, Westermark B, Heldin CH (1990) Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes. J Clin Invest 85:916-920.
38. Smits A, Hermansson M, Nister M, Karnushina I, Heldin CH, Westermark B, Funa K (1989) Rat brain capillary endothelial cells express functional PDGF B-type receptors. Growth Factors 2:1-8.
39. Vernon RB, Sage EH (1995) Between molecules and morphology: Extracellular matrix and creation of vascular form. Am J Pathol 147:873-883.
40. Vernon RB, Angello JC, Iruela-Arispe ML, Lane TF, Sage EH (1992) Reorganization of basement membrane matrices by cellular traction promotes the formation of cellular networks in vitro. Lab Invest 66:536-547.
41. Westermark B, Siegbahn A, Heldin CH, Claesson-Welsh L (1990) B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase. Proc Natl Acad Sci USA 87:128-132.