메뉴 건너뛰기




Volumn 4, Issue FEB, 2013, Pages

Vaccination against lyme disease: Past, present, and future

Author keywords

Borrelia burgdorferi; Ixodes scapularis; Lyme disease; Reservoir; Tick; Vaccine; Vector

Indexed keywords

BACTERIN; BBK32; DECORIN BINDING PROTEIN A; LYME DISEASE VACCINE; NOVIBAC; OUTER SURFACE PROTEIN A; OUTER SURFACE PROTEIN B; OUTER SURFACE PROTEIN C; RECOMBITEK; SALIVA PROTEIN; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; LIPOPROTEIN; MEMBRANE ANTIGEN; OUTER MEMBRANE PROTEIN; VACCINE;

EID: 84894278784     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2013.00006     Document Type: Review
Times cited : (63)

References (178)
  • 1
    • 0024785684 scopus 로고
    • Molecular mimicry and Lyme borreliosis: a shared antigenic determinant between Borrelia burgdorferi and human tissue
    • Aberer, E., Brunner, C., Suchanek, G., Klade, H., Barbour, A., Stanek, G., et al. (1989). Molecular mimicry and Lyme borreliosis: a shared antigenic determinant between Borrelia burgdorferi and human tissue. Ann. Neurol. 26, 732-737.
    • (1989) Ann. Neurol. , vol.26 , pp. 732-737
    • Aberer, E.1    Brunner, C.2    Suchanek, G.3    Klade, H.4    Barbour, A.5    Stanek, G.6
  • 2
    • 84934440272 scopus 로고    scopus 로고
    • Paratransgenesis applied for control of tsetse transmitted sleeping sickness
    • Aksoy, S., Weiss, B., and Attardo, G. (2008). Paratransgenesis applied for control of tsetse transmitted sleeping sickness. Adv. Exp. Med. Biol. 627, 35-48.
    • (2008) Adv. Exp. Med. Biol. , vol.627 , pp. 35-48
    • Aksoy, S.1    Weiss, B.2    Attardo, G.3
  • 3
    • 0024674186 scopus 로고
    • Immunology of interactions between ticks and laboratory animals
    • Allen, J. R. (1989). Immunology of interactions between ticks and laboratory animals. Exp. Appl. Acarol. 7, 5-13.
    • (1989) Exp. Appl. Acarol. , vol.7 , pp. 5-13
    • Allen, J.R.1
  • 4
    • 0024722869 scopus 로고
    • Epizootiology of Borrelia in Ixodes tick vectors and reservoir hosts
    • Anderson, J. F. (1989). Epizootiology of Borrelia in Ixodes tick vectors and reservoir hosts. Rev. Infect. Dis. 11(Suppl. 6), S1451-S1459.
    • (1989) Rev. Infect. Dis. , vol.11 , Issue.SUPPL. 6
    • Anderson, J.F.1
  • 5
    • 0023269489 scopus 로고
    • Seasonal prevalence of Borrelia burgdorferi in natural populations of white-footed mice, Peromyscus leucopus
    • Anderson, J. F., Johnson, R. C., and Magnarelli, L. A. (1987). Seasonal prevalence of Borrelia burgdorferi in natural populations of white-footed mice, Peromyscus leucopus. J. Clin. Microbiol. 25, 1564-1566.
    • (1987) J. Clin. Microbiol. , vol.25 , pp. 1564-1566
    • Anderson, J.F.1    Johnson, R.C.2    Magnarelli, L.A.3
  • 7
    • 60849099047 scopus 로고    scopus 로고
    • Exploring the mialome of ticks: an annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae)
    • doi: 10.1186/1471-2164-9-552
    • Anderson, J. M., Sonenshine, D. E., and Valenzuela, J. G. (2008). Exploring the mialome of ticks: an annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae). BMC Genomics 9:552. doi: 10.1186/1471-2164-9-552
    • (2008) BMC Genomics , vol.9 , pp. 552
    • Anderson, J.M.1    Sonenshine, D.E.2    Valenzuela, J.G.3
  • 8
    • 18444406853 scopus 로고    scopus 로고
    • Salp15, an Ixodes scapularis salivary protein, inhibits CD4(+) T cell activation
    • Anguita, J., Ramamoorthi, N., Hovius, J. W., Das, S., Thomas, V., Persinski, R., et al. (2002). Salp15, an Ixodes scapularis salivary protein, inhibits CD4(+) T cell activation. Immunity 16, 849-859.
    • (2002) Immunity , vol.16 , pp. 849-859
    • Anguita, J.1    Ramamoorthi, N.2    Hovius, J.W.3    Das, S.4    Thomas, V.5    Persinski, R.6
  • 9
    • 65249091957 scopus 로고    scopus 로고
    • HLA type and immune response to Borrelia burgdorferi outer surface protein a in people in whom arthritis developed after Lyme disease vaccination
    • Ball, R., Shadomy, S. V., Meyer, A., Huber, B. T., Leffell, M. S., Zachary, A., et al. (2009). HLA type and immune response to Borrelia burgdorferi outer surface protein a in people in whom arthritis developed after Lyme disease vaccination. Arthritis Rheum. 60, 1179-1186.
    • (2009) Arthritis Rheum , vol.60 , pp. 1179-1186
    • Ball, R.1    Shadomy, S.V.2    Meyer, A.3    Huber, B.T.4    Leffell, M.S.5    Zachary, A.6
  • 10
    • 0027170272 scopus 로고
    • The biological and social phenomenon of Lyme disease
    • Barbour, A. G., and Fish, D. (1993). The biological and social phenomenon of Lyme disease. Science 260, 1610-1616.
    • (1993) Science , vol.260 , pp. 1610-1616
    • Barbour, A.G.1    Fish, D.2
  • 11
    • 0030741615 scopus 로고    scopus 로고
    • Protective and arthritis-resolving activity in sera of mice infected with Borrelia burgdorferi
    • Barthold, S. W., Feng, S., Bockenstedt, L. K., Fikrig, E., and Feen, K. (1997). Protective and arthritis-resolving activity in sera of mice infected with Borrelia burgdorferi. Clin. Infect. Dis. 25, S9-S17.
    • (1997) Clin. Infect. Dis. , vol.25
    • Barthold, S.W.1    Feng, S.2    Bockenstedt, L.K.3    Fikrig, E.4    Feen, K.5
  • 12
    • 84865540659 scopus 로고    scopus 로고
    • Oral vaccination with vaccinia virus expressing the tick antigen subolesin inhibits tick feeding and transmission of Borrelia burgdorferi
    • Bensaci, M., Bhattacharya, D., Clark, R., and Hu, L. T. (2012). Oral vaccination with vaccinia virus expressing the tick antigen subolesin inhibits tick feeding and transmission of Borrelia burgdorferi. Vaccine 30, 6040-6046.
    • (2012) Vaccine , vol.30 , pp. 6040-6046
    • Bensaci, M.1    Bhattacharya, D.2    Clark, R.3    Hu, L.T.4
  • 13
    • 80053611083 scopus 로고    scopus 로고
    • Development of a baited oral vaccine for use in reservoir-targeted strategies against Lyme disease
    • Bhattacharya, D., Bensaci, M., Luker, K. E., Luker, G., Wisdom, S., Telford, S. R., et al. (2011). Development of a baited oral vaccine for use in reservoir-targeted strategies against Lyme disease. Vaccine 29, 7818-7825.
    • (2011) Vaccine , vol.29 , pp. 7818-7825
    • Bhattacharya, D.1    Bensaci, M.2    Luker, K.E.3    Luker, G.4    Wisdom, S.5    Telford, S.R.6
  • 14
    • 78249243856 scopus 로고    scopus 로고
    • Development of a vaccinia virus based reservoir-targeted vaccine against Yersinia pestis
    • Bhattacharya, D., Mecsas, J., and Hu, L. T. (2010). Development of a vaccinia virus based reservoir-targeted vaccine against Yersinia pestis. Vaccine 28, 7683-7689.
    • (2010) Vaccine , vol.28 , pp. 7683-7689
    • Bhattacharya, D.1    Mecsas, J.2    Hu, L.T.3
  • 15
    • 84972102698 scopus 로고
    • Ixodes ricinus L.: mast cells, basophils and eosinophils in the sequence of cellular events in the skin of infested or re-infested rabbits
    • Brossard, M., and Fivaz, V. (1982). Ixodes ricinus L.: mast cells, basophils and eosinophils in the sequence of cellular events in the skin of infested or re-infested rabbits. Parasitology 85, 583-592.
    • (1982) Parasitology , vol.85 , pp. 583-592
    • Brossard, M.1    Fivaz, V.2
  • 16
    • 18844363955 scopus 로고    scopus 로고
    • Multicomponent Lyme vaccine: three is not a crowd
    • Brown, E. L., Kim, J. H., Reisenbichler, E. S., and Höök, M. (2005). Multicomponent Lyme vaccine: three is not a crowd. Vaccine 23, 3687-3696.
    • (2005) Vaccine , vol.23 , pp. 3687-3696
    • Brown, E.L.1    Kim, J.H.2    Reisenbichler, E.S.3    Höök, M.4
  • 17
    • 0020410072 scopus 로고
    • Antibody- and cell-mediated immune resistance by guinea pigs to adult Amblyomma americanum ticks
    • Brown, S. J. (1982). Antibody- and cell-mediated immune resistance by guinea pigs to adult Amblyomma americanum ticks. Am. J. Trop. Med. Hyg. 31, 1285-1290.
    • (1982) Am. J. Trop. Med. Hyg. , vol.31 , pp. 1285-1290
    • Brown, S.J.1
  • 18
    • 0020518537 scopus 로고
    • Immune rejection of ectoparasites (ticks) by T cell and IgG1 antibody recruitment of basophils and eosinophils
    • Brown, S. J., and Askenase, P. W. (1983). Immune rejection of ectoparasites (ticks) by T cell and IgG1 antibody recruitment of basophils and eosinophils. Fed. Proc. 42, 1744-1749.
    • (1983) Fed. Proc. , vol.42 , pp. 1744-1749
    • Brown, S.J.1    Askenase, P.W.2
  • 19
    • 0021949504 scopus 로고
    • Rejection of ticks from guinea pigs by anti-hapten-antibody-mediated degranulation of basophils at cutaneous basophil hypersensitivity sites: role of mediators other than histamine
    • Brown, S. J., and Askenase, P. W. (1985). Rejection of ticks from guinea pigs by anti-hapten-antibody-mediated degranulation of basophils at cutaneous basophil hypersensitivity sites: role of mediators other than histamine. J. Immunol. 134, 1160-1165.
    • (1985) J. Immunol. , vol.134 , pp. 1160-1165
    • Brown, S.J.1    Askenase, P.W.2
  • 20
    • 79960492096 scopus 로고    scopus 로고
    • Molting success of Ixodes scapularis varies among individual blood meal hosts and species
    • Brunner, J. L., Cheney, L., Keesing, F., Killilea, M., Logiudice, K., Previtali, A., et al. (2011). Molting success of Ixodes scapularis varies among individual blood meal hosts and species. J. Med. Entomol. 48, 860-866.
    • (2011) J. Med. Entomol. , vol.48 , pp. 860-866
    • Brunner, J.L.1    Cheney, L.2    Keesing, F.3    Killilea, M.4    Logiudice, K.5    Previtali, A.6
  • 21
    • 67649592222 scopus 로고    scopus 로고
    • Conservation and immunogenicity of the mosquito ortholog of the tick-protective antigen, subolesin
    • Canales, M., Naranjo, V., Almazan, C., Molina, R., Tsuruta, S. A., Szabo, M. P., et al. (2009). Conservation and immunogenicity of the mosquito ortholog of the tick-protective antigen, subolesin. Parasitol. Res. 105, 97-111.
    • (2009) Parasitol. Res. , vol.105 , pp. 97-111
    • Canales, M.1    Naranjo, V.2    Almazan, C.3    Molina, R.4    Tsuruta, S.A.5    Szabo, M.P.6
  • 23
    • 70350776545 scopus 로고    scopus 로고
    • Human vaccinia infection after contact with a raccoon rabies vaccine bait - Pennsylvania, 2009
    • CDC. (Atlanta, GA: The Centers for Disease Control and Prevention)
    • CDC. (2009). "Human vaccinia infection after contact with a raccoon rabies vaccine bait - Pennsylvania, 2009," in MMWR (Atlanta, GA: The Centers for Disease Control and Prevention).
    • (2009) MMWR
  • 24
    • 78751512204 scopus 로고    scopus 로고
    • A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
    • Chmelar, J., Oliveira, C. J., Rezacova, P., Francischetti, I. M., Kovarova, Z., Pejler, G., et al. (2011). A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood 117, 736-744.
    • (2011) Blood , vol.117 , pp. 736-744
    • Chmelar, J.1    Oliveira, C.J.2    Rezacova, P.3    Francischetti, I.M.4    Kovarova, Z.5    Pejler, G.6
  • 26
    • 0028115738 scopus 로고
    • Variations in the ospB gene of Borrelia burgdorferi result in differences in monoclonal antibody reactivity and in production of escape variants
    • Coleman, J. L., Rogers, R. C., Rosa, P. A., and Benach, J. L. (1994). Variations in the ospB gene of Borrelia burgdorferi result in differences in monoclonal antibody reactivity and in production of escape variants. Infect. Immun. 62, 303-307.
    • (1994) Infect. Immun. , vol.62 , pp. 303-307
    • Coleman, J.L.1    Rogers, R.C.2    Rosa, P.A.3    Benach, J.L.4
  • 27
    • 0002477697 scopus 로고    scopus 로고
    • Efficacy of a nonadjuvanted, outer surface protein A, recombinant vaccine in dogs after challenge by ticks naturally infected with Borrelia burgdorferi
    • Conlon, J. A., Mather, T. N., Tanner, P., Gallo, G., and Jacobson, R. H. (2000). Efficacy of a nonadjuvanted, outer surface protein A, recombinant vaccine in dogs after challenge by ticks naturally infected with Borrelia burgdorferi. Vet. Ther. 1, 96-107.
    • (2000) Vet. Ther. , vol.1 , pp. 96-107
    • Conlon, J.A.1    Mather, T.N.2    Tanner, P.3    Gallo, G.4    Jacobson, R.H.5
  • 28
    • 79251473364 scopus 로고    scopus 로고
    • Tick histamine release factor is critical for Ixodes scapularis engorgement and transmission of the lyme disease agent
    • doi: 10.1371/journal.ppat.1001205
    • Dai, J., Narasimhan, S., Zhang, L., Liu, L., Wang, P., and Fikrig, E. (2010). Tick histamine release factor is critical for Ixodes scapularis engorgement and transmission of the lyme disease agent. PLoS Pathog. 6:e1001205. doi: 10.1371/journal.ppat.1001205
    • (2010) PLoS Pathog , vol.6
    • Dai, J.1    Narasimhan, S.2    Zhang, L.3    Liu, L.4    Wang, P.5    Fikrig, E.6
  • 29
    • 71749104437 scopus 로고    scopus 로고
    • Antibodies against a tick protein, Salp15, protect mice from the Lyme disease agent
    • Dai, J., Wang, P., Adusumilli, S., Booth, C. J., Narasimhan, S., Anguita, J., et al. (2009). Antibodies against a tick protein, Salp15, protect mice from the Lyme disease agent. Cell Host Microbe 6, 482-492.
    • (2009) Cell Host Microbe , vol.6 , pp. 482-492
    • Dai, J.1    Wang, P.2    Adusumilli, S.3    Booth, C.J.4    Narasimhan, S.5    Anguita, J.6
  • 30
    • 33847755175 scopus 로고    scopus 로고
    • Ixodes ticks belonging to the Ixodes ricinus complex encode a family of anticomplement proteins
    • Daix, V., Schroeder, H., Praet, N., Georgin, J. P., Chiappino, I., Gillet, L., et al. (2007). Ixodes ticks belonging to the Ixodes ricinus complex encode a family of anticomplement proteins. Insect Mol. Biol. 16, 155-166.
    • (2007) Insect Mol. Biol. , vol.16 , pp. 155-166
    • Daix, V.1    Schroeder, H.2    Praet, N.3    Georgin, J.P.4    Chiappino, I.5    Gillet, L.6
  • 31
    • 0035887953 scopus 로고    scopus 로고
    • Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands
    • Das, S., Banerjee, G., Deponte, K., Marcantonio, N., Kantor, F. S., and Fikrig, E. (2001). Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands. J. Infect. Dis. 184, 1056-1064.
    • (2001) J. Infect. Dis. , vol.184 , pp. 1056-1064
    • Das, S.1    Banerjee, G.2    Deponte, K.3    Marcantonio, N.4    Kantor, F.S.5    Fikrig, E.6
  • 32
    • 20944445785 scopus 로고    scopus 로고
    • RNA interference screening in ticks for identification of protective antigens
    • De La Fuente, J., Almazan, C., Blouin, E. F., Naranjo, V., and Kocan, K. M. (2005). RNA interference screening in ticks for identification of protective antigens. Parasitol. Res. 96, 137-141.
    • (2005) Parasitol. Res. , vol.96 , pp. 137-141
    • De La Fuente, J.1    Almazan, C.2    Blouin, E.F.3    Naranjo, V.4    Kocan, K.M.5
  • 33
    • 33751210658 scopus 로고    scopus 로고
    • Reduction of tick infections with Anaplasma marginale and A. phagocytophilum by targeting the tick protective antigen subolesin
    • De La Fuente, J., Almazan, C., Blouin, E. F., Naranjo, V., and Kocan, K. M. (2006). Reduction of tick infections with Anaplasma marginale and A. phagocytophilum by targeting the tick protective antigen subolesin. Parasitol. Res. 100, 85-91.
    • (2006) Parasitol. Res. , vol.100 , pp. 85-91
    • De La Fuente, J.1    Almazan, C.2    Blouin, E.F.3    Naranjo, V.4    Kocan, K.M.5
  • 34
    • 84860389760 scopus 로고    scopus 로고
    • Targeting arthropod subolesin/akirin for the development of a universal vaccine for control of vector infestations and pathogen transmission
    • De La Fuente, J., Moreno-Cid, J. A., Canales, M., Villar, M., De La Lastra, J. M., Kocan, K. M., et al. (2011). Targeting arthropod subolesin/akirin for the development of a universal vaccine for control of vector infestations and pathogen transmission. Vet. Parasitol. 181, 17-22.
    • (2011) Vet. Parasitol. , vol.181 , pp. 17-22
    • De La Fuente, J.1    Moreno-Cid, J.A.2    Canales, M.3    Villar, M.4    De La Lastra, J.M.5    Kocan, K.M.6
  • 35
    • 0030025949 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine
    • De Silva, A. M., Telford, S. R. 3rd., Brunet, L. R., Barthold, S. W., and Fikrig, E. (1996). Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. Med. 183, 271-275.
    • (1996) J. Exp. Med. , vol.183 , pp. 271-275
    • De Silva, A.M.1    Telford III, S.R.2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 36
    • 0032950531 scopus 로고    scopus 로고
    • Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks
    • De Silva, A. M., Zeidner, N. S., Zhang, Y., Dolan, M. C., Piesman, J., and Fikrig, E. (1999). Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks. Infect. Immun. 67, 30-35.
    • (1999) Infect. Immun. , vol.67 , pp. 30-35
    • De Silva, A.M.1    Zeidner, N.S.2    Zhang, Y.3    Dolan, M.C.4    Piesman, J.5    Fikrig, E.6
  • 37
    • 72849134856 scopus 로고    scopus 로고
    • Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks
    • Dunham-Ems, S. M., Caimano, M. J., Pal, U., Wolgemuth, C. W., Eggers, C. H., Balic, A., et al. (2009). Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks. J. Clin. Invest. 119, 3652-3665.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3652-3665
    • Dunham-Ems, S.M.1    Caimano, M.J.2    Pal, U.3    Wolgemuth, C.W.4    Eggers, C.H.5    Balic, A.6
  • 38
    • 34047168361 scopus 로고    scopus 로고
    • Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens
    • Earnhart, C. G., and Marconi, R. T. (2007a). Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens. Vaccine 25, 3419-3427.
    • (2007) Vaccine , vol.25 , pp. 3419-3427
    • Earnhart, C.G.1    Marconi, R.T.2
  • 39
    • 37649013925 scopus 로고    scopus 로고
    • An octavalent lyme disease vaccine induces antibodies that recognize all incorporated OspC type-specific sequences
    • Earnhart, C. G., and Marconi, R. T. (2007b). An octavalent lyme disease vaccine induces antibodies that recognize all incorporated OspC type-specific sequences. Hum. Vaccin. 3, 281-289.
    • (2007) Hum. Vaccin. , vol.3 , pp. 281-289
    • Earnhart, C.G.1    Marconi, R.T.2
  • 40
    • 79958011550 scopus 로고    scopus 로고
    • Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate
    • Earnhart, C. G., Rhodes, D. V. L., and Marconi, R. T. (2011). Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate. Clin. Vaccine Immunol. 18, 901-906.
    • (2011) Clin. Vaccine Immunol. , vol.18 , pp. 901-906
    • Earnhart, C.G.1    Rhodes, D.V.L.2    Marconi, R.T.3
  • 41
    • 0016803762 scopus 로고
    • Reinfection of vervet monkeys (Cercopithecus aethiops) with Borrelia hermsii
    • Felsenfeld, O., and Wolf, R. H. (1975). Reinfection of vervet monkeys (Cercopithecus aethiops) with Borrelia hermsii. Res. Commun. Chem. Pathol. Pharmacol. 11, 147-150.
    • (1975) Res. Commun. Chem. Pathol. Pharmacol. , vol.11 , pp. 147-150
    • Felsenfeld, O.1    Wolf, R.H.2
  • 42
    • 0031303476 scopus 로고    scopus 로고
    • Protective antibodies develop, and murine Lyme arthritis regresses, in the absence of MHC class II and CD4+ T cells
    • Fikrig, E., Barthold, S. W., Chen, M., Chang, C. H., and Flavell, R. A. (1997). Protective antibodies develop, and murine Lyme arthritis regresses, in the absence of MHC class II and CD4+ T cells. J. Immunol. 159, 5682-5686.
    • (1997) J. Immunol. , vol.159 , pp. 5682-5686
    • Fikrig, E.1    Barthold, S.W.2    Chen, M.3    Chang, C.H.4    Flavell, R.A.5
  • 43
    • 0025202254 scopus 로고
    • Protection of mice against the Lyme disease agent by immunizing with recombinant OspA
    • Fikrig, E., Barthold, S. W., Kantor, F. S., and Flavell, R. A. (1990). Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science 250, 553-556.
    • (1990) Science , vol.250 , pp. 553-556
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 44
    • 0026507230 scopus 로고
    • Long-term protection of mice from Lyme disease by vaccination with OspA
    • Fikrig, E., Barthold, S. W., Kantor, F. S., and Flavell, R. A. (1992a). Long-term protection of mice from Lyme disease by vaccination with OspA. Infect. Immun. 60, 773-777.
    • (1992) Infect. Immun. , vol.60 , pp. 773-777
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 46
    • 0028008686 scopus 로고
    • Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis
    • Fikrig, E., Bockenstedt, L. K., Barthold, S. W., Chen, M., Tao, H., Salaam, P. A., et al. (1994). Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis. J. Infect. Dis. 169, 568-574.
    • (1994) J. Infect. Dis. , vol.169 , pp. 568-574
    • Fikrig, E.1    Bockenstedt, L.K.2    Barthold, S.W.3    Chen, M.4    Tao, H.5    Salaam, P.A.6
  • 47
    • 0034657179 scopus 로고    scopus 로고
    • Arthropod- and host-specific Borrelia burgdorferi bbk32 expression and the inhibition of spirochete transmission
    • Fikrig, E., Feng, W., Barthold, S. W., Telford, S. R. 3rd., and Flavell, R. A. (2000). Arthropod- and host-specific Borrelia burgdorferi bbk32 expression and the inhibition of spirochete transmission. J. Immunol. 164, 5344-5351.
    • (2000) J. Immunol. , vol.164 , pp. 5344-5351
    • Fikrig, E.1    Feng, W.2    Barthold, S.W.3    Telford III, S.R.4    Flavell, R.A.5
  • 48
    • 0027238219 scopus 로고
    • Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B
    • Fikrig, E., Tao, H., Kantor, F. S., Barthold, S. W., and Flavell, R. A. (1993). Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B. Proc. Natl. Acad. Sci. U.S.A. 90, 4092-4096.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 4092-4096
    • Fikrig, E.1    Tao, H.2    Kantor, F.S.3    Barthold, S.W.4    Flavell, R.A.5
  • 49
    • 0037904919 scopus 로고    scopus 로고
    • Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis
    • Francischetti, I. M., Mather, T. N., and Ribeiro, J. M. (2003). Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis. Biochem. Biophys. Res. Commun. 305, 869-875.
    • (2003) Biochem. Biophys. Res. Commun. , vol.305 , pp. 869-875
    • Francischetti, I.M.1    Mather, T.N.2    Ribeiro, J.M.3
  • 50
    • 2442483514 scopus 로고    scopus 로고
    • Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease
    • Francischetti, I. M., Mather, T. N., and Ribeiro, J. M. (2004). Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease, Ixodes scapularis. Thromb. Haemost. 91, 886-898.
    • (2004) Ixodes scapularis. Thromb. Haemost. , vol.91 , pp. 886-898
    • Francischetti, I.M.1    Mather, T.N.2    Ribeiro, J.M.3
  • 51
    • 23444459542 scopus 로고    scopus 로고
    • The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae)
    • Francischetti, I. M., My Pham, V., Mans, B. J., Andersen, J. F., Mather, T. N., Lane, R. S., et al. (2005). The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae). Insect Biochem. Mol. Biol. 35, 1142-1161.
    • (2005) Insect Biochem. Mol. Biol. , vol.35 , pp. 1142-1161
    • Francischetti, I.M.1    My Pham, V.2    Mans, B.J.3    Andersen, J.F.4    Mather, T.N.5    Lane, R.S.6
  • 52
    • 0037093065 scopus 로고    scopus 로고
    • Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex
    • Francischetti, I. M., Valenzuela, J. G., Andersen, J. F., Mather, T. N., and Ribeiro, J. M. (2002). Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex. Blood 99, 3602-3612.
    • (2002) Blood , vol.99 , pp. 3602-3612
    • Francischetti, I.M.1    Valenzuela, J.G.2    Andersen, J.F.3    Mather, T.N.4    Ribeiro, J.M.5
  • 53
    • 56649094523 scopus 로고    scopus 로고
    • Epidemiological situation of Lyme borreliosis in Germany: surveillance data from six Eastern German States, 2002 to 2006
    • Fülöp, B., and Poggensee, G. (2008). Epidemiological situation of Lyme borreliosis in Germany: surveillance data from six Eastern German States, 2002 to 2006. Parasitol. Res. 103, 117-120.
    • (2008) Parasitol. Res. , vol.103 , pp. 117-120
    • Fülöp, B.1    Poggensee, G.2
  • 55
    • 0029121025 scopus 로고
    • Experimental immunization with Borrelia burgdorferi induces development of antibodies to gangliosides
    • Garcia-Monco, J. C., Seidman, R. J., and Benach, J. L. (1995). Experimental immunization with Borrelia burgdorferi induces development of antibodies to gangliosides. Infect. Immun. 63, 4130-4137.
    • (1995) Infect. Immun. , vol.63 , pp. 4130-4137
    • Garcia-Monco, J.C.1    Seidman, R.J.2    Benach, J.L.3
  • 56
    • 0035313541 scopus 로고    scopus 로고
    • Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis
    • Gillespie, R. D., Dolan, M. C., Piesman, J., and Titus, R. G. (2001). Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis. J. Immunol. 166, 4319-4326.
    • (2001) J. Immunol. , vol.166 , pp. 4319-4326
    • Gillespie, R.D.1    Dolan, M.C.2    Piesman, J.3    Titus, R.G.4
  • 57
    • 0037765131 scopus 로고    scopus 로고
    • Inability of outer-surface protein C (OspC)-primed mice to elicit a protective anamnestic immune response to a tick-transmitted challenge of Borrelia burgdorferi
    • Gilmore, R. D. Jr., Bacon, R. M., Carpio, A. M., Piesman, J., Dolan, M. C., and Mbow, M. L. (2003). Inability of outer-surface protein C (OspC)-primed mice to elicit a protective anamnestic immune response to a tick-transmitted challenge of Borrelia burgdorferi. J. Med. Microbiol. 52, 551-556.
    • (2003) J. Med. Microbiol. , vol.52 , pp. 551-556
    • Gilmore Jr., R.D.1    Bacon, R.M.2    Carpio, A.M.3    Piesman, J.4    Dolan, M.C.5    Mbow, M.L.6
  • 58
    • 0029948977 scopus 로고    scopus 로고
    • Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC
    • Gilmore, R. D. Jr., Kappel, K. J., Dolan, M. C., Burkot, T. R., and Johnson, B. J. (1996). Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC. Infect. Immun. 64, 2234-2239.
    • (1996) Infect. Immun. , vol.64 , pp. 2234-2239
    • Gilmore Jr., R.D.1    Kappel, K.J.2    Dolan, M.C.3    Burkot, T.R.4    Johnson, B.J.5
  • 59
    • 0031029091 scopus 로고    scopus 로고
    • Reactivity with a specific epitope of outer surface protein A predicts protection from infection with the Lyme disease spirochete, Borrelia burgdorferi
    • Golde, W. T., Piesman, J., Dolan, M. C., Kramer, M., Hauser, P., Lobet, Y., et al. (1997). Reactivity with a specific epitope of outer surface protein A predicts protection from infection with the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 65, 882-889.
    • (1997) Infect. Immun. , vol.65 , pp. 882-889
    • Golde, W.T.1    Piesman, J.2    Dolan, M.C.3    Kramer, M.4    Hauser, P.5    Lobet, Y.6
  • 60
    • 0031897535 scopus 로고    scopus 로고
    • Culture-confirmed reinfection of a person with different strains of Borrelia burgdorferi sensu stricto
    • Golde, W. T., Robinson-Dunn, B., Stobierski, M. G., Dykhuizen, D., Wang, I.-N., Carlson, V., et al. (1998). Culture-confirmed reinfection of a person with different strains of Borrelia burgdorferi sensu stricto. J. Clin. Microbiol. 36, 1015-1019.
    • (1998) J. Clin. Microbiol. , vol.36 , pp. 1015-1019
    • Golde, W.T.1    Robinson-Dunn, B.2    Stobierski, M.G.3    Dykhuizen, D.4    Wang, I.-N.5    Carlson, V.6
  • 61
    • 33646471963 scopus 로고    scopus 로고
    • Oral vaccine that breaks the transmission cycle of the Lyme disease spirochete can be delivered via bait
    • Gomes-Solecki, M. J., Brisson, D. R., and Dattwyler, R. J. (2006). Oral vaccine that breaks the transmission cycle of the Lyme disease spirochete can be delivered via bait. Vaccine 24, 4440-4449.
    • (2006) Vaccine , vol.24 , pp. 4440-4449
    • Gomes-Solecki, M.J.1    Brisson, D.R.2    Dattwyler, R.J.3
  • 62
    • 84897923596 scopus 로고    scopus 로고
    • Tick-Borne Diseases of Humans. Washington, DC: ASM Press. Gross, D. M., Forsthuber, T., Tary-Lehmann, M., Etling, C., Ito, K., Nagy, Z. A., et al. (1998). Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis
    • Goodman, J. L., Dennis, D. T., and Sonenshine, D. E. (2005). Tick-Borne Diseases of Humans. Washington, DC: ASM Press. Gross, D. M., Forsthuber, T., Tary-Lehmann, M., Etling, C., Ito, K., Nagy, Z. A., et al. (1998). Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis. Science 281, 703-706.
    • (2005) Science , vol.281 , pp. 703-706
    • Goodman, J.L.1    Dennis, D.T.2    Sonenshine, D.E.3
  • 63
    • 66549105719 scopus 로고    scopus 로고
    • Inhibition of neutrophil function by two tick salivary proteins
    • Guo, X., Booth, C. J., Paley, M. A., Wang, X., Deponte, K., Fikrig, E., et al. (2009). Inhibition of neutrophil function by two tick salivary proteins. Infect. Immun. 77, 2320-2329.
    • (2009) Infect. Immun. , vol.77 , pp. 2320-2329
    • Guo, X.1    Booth, C.J.2    Paley, M.A.3    Wang, X.4    Deponte, K.5    Fikrig, E.6
  • 64
    • 0033914286 scopus 로고    scopus 로고
    • Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks
    • Hagman, K. E., Yang, X., Wikel, S. K., Schoeler, G. B., Caimano, M. J., Radolf, J. D., et al. (2000). Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks. Infect. Immun. 68, 4759-4764.
    • (2000) Infect. Immun. , vol.68 , pp. 4759-4764
    • Hagman, K.E.1    Yang, X.2    Wikel, S.K.3    Schoeler, G.B.4    Caimano, M.J.5    Radolf, J.D.6
  • 65
    • 58549114037 scopus 로고    scopus 로고
    • Use of tick surveys and serosurveys to evaluate pet dogs as a sentinel species for emerging Lyme disease
    • Hamer, S. A., Tsao, J. I., Walker, E. D., Mansfield, L. S., Foster, E. S., and Hickling, G. J. (2009). Use of tick surveys and serosurveys to evaluate pet dogs as a sentinel species for emerging Lyme disease. Am. J. Vet. Res. 70, 49-56.
    • (2009) Am. J. Vet. Res. , vol.70 , pp. 49-56
    • Hamer, S.A.1    Tsao, J.I.2    Walker, E.D.3    Mansfield, L.S.4    Foster, E.S.5    Hickling, G.J.6
  • 66
    • 0031925530 scopus 로고    scopus 로고
    • Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection
    • Hanson, M. S., Cassatt, D. R., Guo, B. P., Patel, N. K., McCarthy, M. P., Dorward, D. W., et al. (1998). Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection. Infect. Immun. 66, 2143-2153.
    • (1998) Infect. Immun. , vol.66 , pp. 2143-2153
    • Hanson, M.S.1    Cassatt, D.R.2    Guo, B.P.3    Patel, N.K.4    McCarthy, M.P.5    Dorward, D.W.6
  • 67
    • 84856562398 scopus 로고    scopus 로고
    • Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs
    • doi: 10.1186/1756-3305-5-26
    • Heinze, D. M., Wikel, S. K., Thangamani, S., and Alarcon-Chaidez, F. J. (2012). Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs. Parasit. Vectors 5:26. doi: 10.1186/1756-3305-5-26
    • (2012) Parasit. Vectors , vol.5 , pp. 26
    • Heinze, D.M.1    Wikel, S.K.2    Thangamani, S.3    Alarcon-Chaidez, F.J.4
  • 68
    • 79960122164 scopus 로고    scopus 로고
    • How big is the Lyme problem? Using novel methods to estimate the true number of Lyme disease cases in British Columbia residents from 1997 to 2008
    • Henry, B., Roth, D., Reilly, R., Macdougall, L., Mak, S., Li, M., et al. (2011). How big is the Lyme problem? Using novel methods to estimate the true number of Lyme disease cases in British Columbia residents from 1997 to 2008. Vector Borne Zoonotic Dis. 11, 863-868.
    • (2011) Vector Borne Zoonotic Dis , vol.11 , pp. 863-868
    • Henry, B.1    Roth, D.2    Reilly, R.3    Macdougall, L.4    Mak, S.5    Li, M.6
  • 69
    • 15044342339 scopus 로고    scopus 로고
    • The Ixodes scapularis Genome Project: an opportunity for advancing tick research
    • Hill, C. A., and Wikel, S. K. (2005). The Ixodes scapularis Genome Project: an opportunity for advancing tick research. Trends Parasitol. 21, 151-153.
    • (2005) Trends Parasitol , vol.21 , pp. 151-153
    • Hill, C.A.1    Wikel, S.K.2
  • 70
    • 40349094836 scopus 로고    scopus 로고
    • Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization
    • doi: 10.1371/journal.ppat.0040031
    • Hovius, J. W., De Jong, M. A., Den Dunnen, J., Litjens, M., Fikrig, E., Van Der Poll, T., et al. (2008a). Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization. PLoS Pathog. 4:e31. doi: 10.1371/journal.ppat.0040031
    • (2008) PLoS Pathog , vol.4
    • Hovius, J.W.1    De Jong, M.A.2    Den Dunnen, J.3    Litjens, M.4    Fikrig, E.5    Van Der Poll, T.6
  • 71
    • 39849098637 scopus 로고    scopus 로고
    • Salivating for knowledge: potential pharmacological agents in tick saliva
    • doi: 10.1371/journal.pmed.0050043
    • Hovius, J. W., Levi, M., and Fikrig, E. (2008b). Salivating for knowledge: potential pharmacological agents in tick saliva. PLoS Med. 5:e43. doi: 10.1371/journal.pmed.0050043
    • (2008) PLoS Med , vol.5
    • Hovius, J.W.1    Levi, M.2    Fikrig, E.3
  • 72
    • 54749147046 scopus 로고    scopus 로고
    • Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva
    • Hovius, J. W., Schuijt, T. J., De Groot, K. A., Roelofs, J. J., Oei, G. A., Marquart, J. A., et al. (2008c). Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva. J. Infect. Dis. 198, 1189-1197.
    • (2008) J. Infect. Dis. , vol.198 , pp. 1189-1197
    • Hovius, J.W.1    Schuijt, T.J.2    De Groot, K.A.3    Roelofs, J.J.4    Oei, G.A.5    Marquart, J.A.6
  • 74
    • 0025425643 scopus 로고
    • Feeding and host preference of immature Ixodes dammini, I. scapularis, and I. pacificus (Acari: Ixodidae)
    • James, A. M., and Oliver, J. H. Jr. (1990). Feeding and host preference of immature Ixodes dammini, I. scapularis, and I. pacificus (Acari: Ixodidae). J. Med. Entomol. 27, 324-330.
    • (1990) J. Med. Entomol. , vol.27 , pp. 324-330
    • James, A.M.1    Oliver Jr., J.H.2
  • 75
    • 0023025241 scopus 로고
    • Active immunization of hamsters against experimental infection with Borrelia burgdorferi
    • Johnson, R. C., Kodner, C., and Russell, M. (1986a). Active immunization of hamsters against experimental infection with Borrelia burgdorferi. Infect. Immun. 54, 897-898.
    • (1986) Infect. Immun. , vol.54 , pp. 897-898
    • Johnson, R.C.1    Kodner, C.2    Russell, M.3
  • 76
    • 0022479177 scopus 로고
    • Passive immunization of hamsters against experimental infection with the Lyme disease spirochete
    • Johnson, R. C., Kodner, C., and Russell, M. (1986b). Passive immunization of hamsters against experimental infection with the Lyme disease spirochete. Infect. Immun. 53, 713-714.
    • (1986) Infect. Immun. , vol.53 , pp. 713-714
    • Johnson, R.C.1    Kodner, C.2    Russell, M.3
  • 78
    • 76949083782 scopus 로고    scopus 로고
    • Functional genomics tool: gene silencing in Ixodes scapularis eggs and nymphs by electroporated dsRNA
    • doi: 10.1186/1472-6750-10-1
    • Karim, S., Troiano, E., and Mather, T. N. (2010). Functional genomics tool: gene silencing in Ixodes scapularis eggs and nymphs by electroporated dsRNA. BMC Biotechnol. 10:1. doi: 10.1186/1472-6750-10-1
    • (2010) BMC Biotechnol , vol.10 , pp. 1
    • Karim, S.1    Troiano, E.2    Mather, T.N.3
  • 79
    • 0030138991 scopus 로고    scopus 로고
    • Ixodes (Ixodes) scapularis (Acari:Ixodidae): redescription of all active stages, distribution, hosts, geographical variation, and medical and veterinary importance
    • Keirans, J. E., Hutcheson, H. J., Durden, L. A., and Klompen, J. S. (1996). Ixodes (Ixodes) scapularis (Acari:Ixodidae): redescription of all active stages, distribution, hosts, geographical variation, and medical and veterinary importance. J. Med. Entomol. 33, 297-318.
    • (1996) J. Med. Entomol. , vol.33 , pp. 297-318
    • Keirans, J.E.1    Hutcheson, H.J.2    Durden, L.A.3    Klompen, J.S.4
  • 80
    • 84858378546 scopus 로고    scopus 로고
    • Passive surveillance for I. scapularis ticks: enhanced analysis for early detection of emerging Lyme disease risk
    • Koffi, J. K., Leighton, P. A., Pelcat, Y., Trudel, L., Lindsay, L. R., Milord, F., et al. (2012). Passive surveillance for I. scapularis ticks: enhanced analysis for early detection of emerging Lyme disease risk. J. Med. Entomol. 49, 400-409.
    • (2012) J. Med. Entomol. , vol.49 , pp. 400-409
    • Koffi, J.K.1    Leighton, P.A.2    Pelcat, Y.3    Trudel, L.4    Lindsay, L.R.5    Milord, F.6
  • 83
    • 54049131201 scopus 로고    scopus 로고
    • Cutting edge: immunity against a "silent" salivary antigen of the Lyme vector Ixodes scapularis impairs its ability to feed
    • Kotsyfakis, M., Anderson, J. M., Andersen, J. F., Calvo, E., Francischetti, I. M., Mather, T. N., et al. (2008). Cutting edge: immunity against a "silent" salivary antigen of the Lyme vector Ixodes scapularis impairs its ability to feed. J. Immunol. 181, 5209-5212.
    • (2008) J. Immunol. , vol.181 , pp. 5209-5212
    • Kotsyfakis, M.1    Anderson, J.M.2    Andersen, J.F.3    Calvo, E.4    Francischetti, I.M.5    Mather, T.N.6
  • 84
    • 77954378928 scopus 로고    scopus 로고
    • The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model
    • Kotsyfakis, M., Horka, H., Salat, J., and Andersen, J. F. (2010). The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Mol. Microbiol. 77, 456-470.
    • (2010) Mol. Microbiol. , vol.77 , pp. 456-470
    • Kotsyfakis, M.1    Horka, H.2    Salat, J.3    Andersen, J.F.4
  • 85
    • 72749114573 scopus 로고    scopus 로고
    • Dermatologic changes induced by repeated Ixodes scapularis bites and implications for prevention of tick-borne infection
    • Krause, P. J., Grant-Kels, J. M., Tahan, S. R., Dardick, K. R., Alarcon-Chaidez, F., Bouchard, K., et al. (2009). Dermatologic changes induced by repeated Ixodes scapularis bites and implications for prevention of tick-borne infection. Vector Borne Zoonotic Dis. 9, 603-610.
    • (2009) Vector Borne Zoonotic Dis , vol.9 , pp. 603-610
    • Krause, P.J.1    Grant-Kels, J.M.2    Tahan, S.R.3    Dardick, K.R.4    Alarcon-Chaidez, F.5    Bouchard, K.6
  • 88
    • 33646248612 scopus 로고    scopus 로고
    • An antivector vaccine protects against a lethal vector-borne pathogen
    • doi: 10.1371/journal.ppat.0020027
    • Labuda, M., Trimnell, A. R., Lickova, M., Kazimirova, M., Davies, G. M., Lissina, O., et al. (2006). An antivector vaccine protects against a lethal vector-borne pathogen. PLoS Pathog. 2:e27. doi: 10.1371/journal.ppat.0020027
    • (2006) PLoS Pathog , vol.2
    • Labuda, M.1    Trimnell, A.R.2    Lickova, M.3    Kazimirova, M.4    Davies, G.M.5    Lissina, O.6
  • 89
    • 0031917278 scopus 로고    scopus 로고
    • Borreliacidal factor in the blood of the western fence lizard (Sceloporus occidentalis)
    • Lane, R. S., and Quistad, G. B. (1998). Borreliacidal factor in the blood of the western fence lizard (Sceloporus occidentalis). J. Parasitol. 84, 29-34.
    • (1998) J. Parasitol. , vol.84 , pp. 29-34
    • Lane, R.S.1    Quistad, G.B.2
  • 90
    • 0037154759 scopus 로고    scopus 로고
    • Adverse event reports following vaccination for Lyme disease: December 1998-July 2000
    • Lathrop, S. L., Ball, R., Haber, P., Mootrey, G. T., Braun, M. M., Shadomy, S. V., et al. (2002). Adverse event reports following vaccination for Lyme disease: December 1998-July 2000. Vaccine 20, 1603-1608.
    • (2002) Vaccine , vol.20 , pp. 1603-1608
    • Lathrop, S.L.1    Ball, R.2    Haber, P.3    Mootrey, G.T.4    Braun, M.M.5    Shadomy, S.V.6
  • 91
  • 92
    • 0027190448 scopus 로고
    • Performance of a Borrelia burgdorferi bacterin in borreliosis-endemic areas
    • Levy, S. A., Lissman, B. A., and Ficke, C. M. (1993). Performance of a Borrelia burgdorferi bacterin in borreliosis-endemic areas. J. Am. Vet. Med. Assoc. 202, 1834-1838.
    • (1993) J. Am. Vet. Med. Assoc. , vol.202 , pp. 1834-1838
    • Levy, S.A.1    Lissman, B.A.2    Ficke, C.M.3
  • 94
    • 33645571011 scopus 로고    scopus 로고
    • ACVIM small animal consensus statement on Lyme disease in dogs: diagnosis, treatment, and prevention
    • Littman, M. P., Goldstein, R. E., Labato, M. A., Lappin, M. R., and Moore, G. E. (2006). ACVIM small animal consensus statement on Lyme disease in dogs: diagnosis, treatment, and prevention. J. Vet. Intern. Med. 20, 422-434.
    • (2006) J. Vet. Intern. Med. , vol.20 , pp. 422-434
    • Littman, M.P.1    Goldstein, R.E.2    Labato, M.A.3    Lappin, M.R.4    Moore, G.E.5
  • 96
    • 84862624814 scopus 로고    scopus 로고
    • Ecology of Borrelia burgdorferi sensu lato in Europe: transmission dynamics in multi-host systems, influence of molecular processes and effects of climate change
    • Mannelli, A., Bertolotti, L., Gern, L., and Gray, J. (2012). Ecology of Borrelia burgdorferi sensu lato in Europe: transmission dynamics in multi-host systems, influence of molecular processes and effects of climate change. FEMS Microbiol. Rev. 36, 837-861.
    • (2012) FEMS Microbiol. Rev. , vol.36 , pp. 837-861
    • Mannelli, A.1    Bertolotti, L.2    Gern, L.3    Gray, J.4
  • 97
    • 0024320231 scopus 로고
    • Comparing the relative potential of rodents as reservoirs of the Lyme disease spirochete (Borrelia burgdorferi)
    • Mather, T. N., Wilson, M. L., Moore, S. I., Ribeiro, J. M., and Spielman, A. (1989). Comparing the relative potential of rodents as reservoirs of the Lyme disease spirochete (Borrelia burgdorferi). Am. J. Epidemiol. 130, 143-150.
    • (1989) Am. J. Epidemiol. , vol.130 , pp. 143-150
    • Mather, T.N.1    Wilson, M.L.2    Moore, S.I.3    Ribeiro, J.M.4    Spielman, A.5
  • 98
    • 84860797527 scopus 로고    scopus 로고
    • Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine
    • Mathias, D. K., Plieskatt, J. L., Armistead, J. S., Bethony, J. M., Abdul-Majid, K. B., McMillan, A., et al. (2012). Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine. Infect. Immun. 80, 1606-1614.
    • (2012) Infect. Immun. , vol.80 , pp. 1606-1614
    • Mathias, D.K.1    Plieskatt, J.L.2    Armistead, J.S.3    Bethony, J.M.4    Abdul-Majid, K.B.5    McMillan, A.6
  • 99
    • 84865152716 scopus 로고    scopus 로고
    • Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia
    • Mayne, P. (2011). Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia. Int. J. Gen. Med. 4, 845-852.
    • (2011) Int. J. Gen. Med. , vol.4 , pp. 845-852
    • Mayne, P.1
  • 100
    • 0033850122 scopus 로고    scopus 로고
    • T-cell-independent responses to Borrelia burgdorferi are critical for protective immunity and resolution of lyme disease
    • McKisic, M. D., and Barthold, S. W. (2000). T-cell-independent responses to Borrelia burgdorferi are critical for protective immunity and resolution of lyme disease. Infect. Immun. 68, 5190-5197.
    • (2000) Infect. Immun. , vol.68 , pp. 5190-5197
    • McKisic, M.D.1    Barthold, S.W.2
  • 101
    • 80455164830 scopus 로고    scopus 로고
    • Reservoir targeted vaccine for lyme borreliosis induces a yearlong, neutralizing antibody response to OspA in white-footed mice
    • Meirelles Richer, L., Aroso, M., Contente-Cuomo, T., Ivanova, L., and Gomes-Solecki, M. (2011). Reservoir targeted vaccine for lyme borreliosis induces a yearlong, neutralizing antibody response to OspA in white-footed mice. Clin. Vaccine Immunol. 18, 1809-1816.
    • (2011) Clin. Vaccine Immunol. , vol.18 , pp. 1809-1816
    • Meirelles Richer, L.1    Aroso, M.2    Contente-Cuomo, T.3    Ivanova, L.4    Gomes-Solecki, M.5
  • 102
    • 79951810123 scopus 로고    scopus 로고
    • Control of Rhipicephalus (Boophilus) microplus infestations by the combination of subolesin vaccination and tick autocidal control after subolesin gene knockdown in ticks fed on cattle
    • Merino, O., Almazan, C., Canales, M., Villar, M., Moreno-Cid, J. A., Estrada-Pena, A., et al. (2011). Control of Rhipicephalus (Boophilus) microplus infestations by the combination of subolesin vaccination and tick autocidal control after subolesin gene knockdown in ticks fed on cattle. Vaccine 29, 2248-2254.
    • (2011) Vaccine , vol.29 , pp. 2248-2254
    • Merino, O.1    Almazan, C.2    Canales, M.3    Villar, M.4    Moreno-Cid, J.A.5    Estrada-Pena, A.6
  • 103
    • 0035488012 scopus 로고    scopus 로고
    • Tick-encoded serine proteinase inhibitors (serpins); potential target antigens for tick vaccine development
    • Muleng, A., Sugino, M., Nakajim, M., Sugimoto, C., and Onuma, M. (2001). Tick-encoded serine proteinase inhibitors (serpins); potential target antigens for tick vaccine development. J. Vet. Med. Sci. 63, 1063-1069.
    • (2001) J. Vet. Med. Sci. , vol.63 , pp. 1063-1069
    • Muleng, A.1    Sugino, M.2    Nakajim, M.3    Sugimoto, C.4    Onuma, M.5
  • 104
    • 35449002574 scopus 로고    scopus 로고
    • Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission
    • doi: 10.1371/journal.pone.0000451
    • Narasimhan, S., Deponte, K., Marcantonio, N., Liang, X., Royce, T. E., Nelson, K. F., et al. (2007a). Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission. PLoS ONE 2:e451. doi: 10.1371/journal.pone.0000451
    • (2007) PLoS ONE , vol.2
    • Narasimhan, S.1    Deponte, K.2    Marcantonio, N.3    Liang, X.4    Royce, T.E.5    Nelson, K.F.6
  • 105
    • 34347352122 scopus 로고    scopus 로고
    • A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector
    • Narasimhan, S., Sukumaran, B., Bozdogan, U., Thomas, V., Liang, X., Deponte, K., et al. (2007b). A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector. Cell Host Microbe 2, 7-18.
    • (2007) Cell Host Microbe , vol.2 , pp. 7-18
    • Narasimhan, S.1    Sukumaran, B.2    Bozdogan, U.3    Thomas, V.4    Liang, X.5    Deponte, K.6
  • 108
    • 0034519993 scopus 로고    scopus 로고
    • Complement-mediated killing of Borrelia burgdorferi by nonimmune sera from sika deer
    • Nelson, D. R., Rooney, S., Miller, N. J., and Mather, T. N. (2000). Complement-mediated killing of Borrelia burgdorferi by nonimmune sera from sika deer. J. Parasitol. 86, 1232-1238.
    • (2000) J. Parasitol. , vol.86 , pp. 1232-1238
    • Nelson, D.R.1    Rooney, S.2    Miller, N.J.3    Mather, T.N.4
  • 109
    • 45149104681 scopus 로고    scopus 로고
    • Rabies in Estonia: situation before and after the first campaigns of oral vaccination of wildlife with SAG2 vaccine bait
    • Niin, E., Laine, M., Guiot, A. L., Demerson, J. M., and Cliquet, F. (2008). Rabies in Estonia: situation before and after the first campaigns of oral vaccination of wildlife with SAG2 vaccine bait. Vaccine 26, 3556-3565.
    • (2008) Vaccine , vol.26 , pp. 3556-3565
    • Niin, E.1    Laine, M.2    Guiot, A.L.3    Demerson, J.M.4    Cliquet, F.5
  • 111
    • 20344388535 scopus 로고    scopus 로고
    • Tick-host interactions: saliva-activated transmission
    • Nuttall, P. A., and Labuda, M. (2004). Tick-host interactions: saliva-activated transmission. Parasitology 129(Suppl.), S177-S189.
    • (2004) Parasitology , vol.129 , Issue.SUPPL.
    • Nuttall, P.A.1    Labuda, M.2
  • 113
    • 33645109969 scopus 로고    scopus 로고
    • Exposed and concealed antigens as vaccine targets for controlling ticks and tick-borne diseases
    • Nuttall, P. A., Trimnell, A. R., Kazimirova, M., and Labuda, M. (2006). Exposed and concealed antigens as vaccine targets for controlling ticks and tick-borne diseases. Parasite Immunol. 28, 155-163.
    • (2006) Parasite Immunol , vol.28 , pp. 155-163
    • Nuttall, P.A.1    Trimnell, A.R.2    Kazimirova, M.3    Labuda, M.4
  • 114
    • 2442683013 scopus 로고    scopus 로고
    • Dogs vaccinated with common Lyme disease vaccines do not respond to IR6, the conserved immunodominant region of the VlsE surface protein of Borrelia burgdorferi
    • O'Connor, T. P., Esty, K. J., Hanscom, J. L., Shields, P., and Philipp, M. T. (2004). Dogs vaccinated with common Lyme disease vaccines do not respond to IR6, the conserved immunodominant region of the VlsE surface protein of Borrelia burgdorferi. Clin. Diagn. Lab. Immunol. 11, 458-462.
    • (2004) Clin. Diagn. Lab. Immunol. , vol.11 , pp. 458-462
    • O'Connor, T.P.1    Esty, K.J.2    Hanscom, J.L.3    Shields, P.4    Philipp, M.T.5
  • 115
    • 44949095446 scopus 로고    scopus 로고
    • Risk maps for range expansion of the Lyme disease vector, Ixodes scapularis, in Canada now and with climate change
    • doi: 10.1186/1476-072X-7-24
    • Ogden, N. H., St-Onge, L., Barker, I. K., Brazeau, S., Bigras-Poulin, M., Charron, D. F., et al. (2008). Risk maps for range expansion of the Lyme disease vector, Ixodes scapularis, in Canada now and with climate change. Int. J. Health Geogr. [Electronic Resource] 7:24. doi: 10.1186/1476-072X-7-24
    • (2008) Int. J. Health Geogr. [Electronic Resource] , vol.7 , pp. 24
    • Ogden, N.H.1    St-Onge, L.2    Barker, I.K.3    Brazeau, S.4    Bigras-Poulin, M.5    Charron, D.F.6
  • 117
    • 0033040796 scopus 로고    scopus 로고
    • Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure
    • Paesen, G. C., Adams, P. L., Harlos, K., Nuttall, P. A., and Stuart, D. I. (1999). Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure. Mol. Cell 3, 661-671.
    • (1999) Mol. Cell , vol.3 , pp. 661-671
    • Paesen, G.C.1    Adams, P.L.2    Harlos, K.3    Nuttall, P.A.4    Stuart, D.I.5
  • 119
    • 8344262276 scopus 로고    scopus 로고
    • TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi
    • Pal, U., Li, X., Wang, T., Montgomery, R. R., Ramamoorthi, N., Desilva, A. M., et al. (2004). TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi. Cell 119, 457-468.
    • (2004) Cell , vol.119 , pp. 457-468
    • Pal, U.1    Li, X.2    Wang, T.3    Montgomery, R.R.4    Ramamoorthi, N.5    Desilva, A.M.6
  • 120
    • 84868677248 scopus 로고    scopus 로고
    • The quest for a universal vaccine against ticks: cross-immunity insights
    • Parizi, L. F., Githaka, N. W., Logullo, C., Konnai, S., Masuda, A., Ohashi, K., et al. (2012). The quest for a universal vaccine against ticks: cross-immunity insights. Vet. J. 194, 158-165.
    • (2012) Vet. J. , vol.194 , pp. 158-165
    • Parizi, L.F.1    Githaka, N.W.2    Logullo, C.3    Konnai, S.4    Masuda, A.5    Ohashi, K.6
  • 121
    • 0030632054 scopus 로고    scopus 로고
    • Absence of Lyme disease spirochetes in larval progeny of naturally infected Ixodes scapularis (Acari:Ixodidae) fed on dogs
    • Patrican, L. A. (1997). Absence of Lyme disease spirochetes in larval progeny of naturally infected Ixodes scapularis (Acari:Ixodidae) fed on dogs. J. Med. Entomol. 34, 52-55.
    • (1997) J. Med. Entomol. , vol.34 , pp. 52-55
    • Patrican, L.A.1
  • 122
    • 0028987461 scopus 로고
    • Transmission of Borrelia burgdorferi by Ixodes pacificus nymphs and reservoir competence of deer mice (Peromyscus maniculatus) infected by tick-bite
    • Peavey, C. A., and Lane, R. S. (1995). Transmission of Borrelia burgdorferi by Ixodes pacificus nymphs and reservoir competence of deer mice (Peromyscus maniculatus) infected by tick-bite. J. Parasitol. 81, 175-178.
    • (1995) J. Parasitol. , vol.81 , pp. 175-178
    • Peavey, C.A.1    Lane, R.S.2
  • 123
    • 0030733650 scopus 로고    scopus 로고
    • The outer surface protein A (OspA) vaccine against Lyme disease: efficacy in the rhesus monkey
    • Philipp, M. T., Lobet, Y., Bohm, R. P. Jr., Roberts, E. D., Dennis, V. A., Gu, Y., et al. (1997). The outer surface protein A (OspA) vaccine against Lyme disease: efficacy in the rhesus monkey. Vaccine 15, 1872-1887.
    • (1997) Vaccine , vol.15 , pp. 1872-1887
    • Philipp, M.T.1    Lobet, Y.2    Bohm Jr., R.P.3    Roberts, E.D.4    Dennis, V.A.5    Gu, Y.6
  • 124
    • 0030843505 scopus 로고    scopus 로고
    • Duration of immunity to reinfection with tick-transmitted Borrelia burgdorferi in naturally infected mice
    • Piesman, J., Dolan, M. C., Happ, C. M., Luft, B. J., Rooney, S. E., Mather, T. N., et al. (1997). Duration of immunity to reinfection with tick-transmitted Borrelia burgdorferi in naturally infected mice. Infect. Immun. 65, 4043-4047.
    • (1997) Infect. Immun. , vol.65 , pp. 4043-4047
    • Piesman, J.1    Dolan, M.C.2    Happ, C.M.3    Luft, B.J.4    Rooney, S.E.5    Mather, T.N.6
  • 125
    • 0023148783 scopus 로고
    • Duration of tick attachment and Borrelia burgdorferi transmission
    • Piesman, J., Mather, T. N., Sinsky, R. J., and Spielman, A. (1987). Duration of tick attachment and Borrelia burgdorferi transmission. J. Clin. Microbiol. 25, 557-558.
    • (1987) J. Clin. Microbiol. , vol.25 , pp. 557-558
    • Piesman, J.1    Mather, T.N.2    Sinsky, R.J.3    Spielman, A.4
  • 126
    • 80053562115 scopus 로고    scopus 로고
    • Ecology of Borreliae and their arthropod vectors
    • eds. D. S. Samuels and J. D. Radolf (Norwich UK: Caister Academic Press)
    • Piesman, J., and Schwan, T. G. (2010). "Ecology of Borreliae and their arthropod vectors," in Borrelia: Molecular Biology, Host Interaction and Pathogenesis, eds. D. S. Samuels and J. D. Radolf (Norwich, UK: Caister Academic Press) 251-278.
    • (2010) Borrelia: Molecular Biology, Host Interaction and Pathogenesis , pp. 251-278
    • Piesman, J.1    Schwan, T.G.2
  • 127
    • 79952543170 scopus 로고    scopus 로고
    • Correcting a public health fiasco: the need for a new vaccine against Lyme disease
    • Plotkin, S. A. (2011). Correcting a public health fiasco: the need for a new vaccine against Lyme disease. Clin. Infect. Dis. 52(Suppl. 3), s271-s275.
    • (2011) Clin. Infect. Dis. , vol.52 , Issue.SUPPL. 3
    • Plotkin, S.A.1
  • 128
    • 81255141781 scopus 로고    scopus 로고
    • The development of vaccines: how the past led to the future
    • Plotkin, S. A., and Plotkin, S. L. (2011). The development of vaccines: how the past led to the future. Nat. Rev. Microbiol. 9, 889-893.
    • (2011) Nat. Rev. Microbiol. , vol.9 , pp. 889-893
    • Plotkin, S.A.1    Plotkin, S.L.2
  • 129
    • 79952569307 scopus 로고    scopus 로고
    • Vaccines against Lyme disease: what happened and what lessons can we learn?
    • Poland, G. A. (2011). Vaccines against Lyme disease: what happened and what lessons can we learn? Clin. Infect. Dis. 52, s253-s258.
    • (2011) Clin. Infect. Dis. , vol.52
    • Poland, G.A.1
  • 130
    • 0031027389 scopus 로고    scopus 로고
    • Immunization with outer surface protein (Osp) A, but not OspC, provides cross-protection of mice challenged with North American isolates of Borrelia burgdorferi
    • Probert, W. S., Crawford, M., Cadiz, R. B., and Lefebvre, R. B. (1997). Immunization with outer surface protein (Osp) A, but not OspC, provides cross-protection of mice challenged with North American isolates of Borrelia burgdorferi. J. Infect. Dis. 175, 400-405.
    • (1997) J. Infect. Dis. , vol.175 , pp. 400-405
    • Probert, W.S.1    Crawford, M.2    Cadiz, R.B.3    Lefebvre, R.B.4
  • 131
    • 0028331281 scopus 로고
    • Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen
    • Probert, W. S., and Lefebvre, R. B. (1994). Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen. Infect. Immun. 62, 1920-1926.
    • (1994) Infect. Immun. , vol.62 , pp. 1920-1926
    • Probert, W.S.1    Lefebvre, R.B.2
  • 133
    • 23144451856 scopus 로고    scopus 로고
    • The Lyme disease agent exploits a tick protein to infect the mammalian host
    • Ramamoorthi, N., Narasimhan, S., Pal, U., Bao, F., Yang, X. F., Fish, D., et al. (2005). The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature 436, 573-577.
    • (2005) Nature , vol.436 , pp. 573-577
    • Ramamoorthi, N.1    Narasimhan, S.2    Pal, U.3    Bao, F.4    Yang, X.F.5    Fish, D.6
  • 134
    • 0026336618 scopus 로고
    • Canine seroprevalence and the distribution of Ixodes dammini in an area of emerging Lyme disease
    • Rand, P. W., Smith, R. P. Jr., and Lacombe, E. H. (1991). Canine seroprevalence and the distribution of Ixodes dammini in an area of emerging Lyme disease. Am. J. Public Health 81, 1331-1334.
    • (1991) Am. J. Public Health , vol.81 , pp. 1331-1334
    • Rand, P.W.1    Smith Jr., R.P.2    Lacombe, E.H.3
  • 136
    • 0037208861 scopus 로고    scopus 로고
    • Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives
    • Ribeiro, J. M., and Francischetti, I. M. (2003). Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives. Annu. Rev. Entomol. 48, 73-88.
    • (2003) Annu. Rev. Entomol. , vol.48 , pp. 73-88
    • Ribeiro, J.M.1    Francischetti, I.M.2
  • 138
    • 23844472248 scopus 로고    scopus 로고
    • Lyme disease agent borrows a practical coat
    • Rosa, P. (2005). Lyme disease agent borrows a practical coat. Nat. Med. 11, 831-832.
    • (2005) Nat. Med. , vol.11 , pp. 831-832
    • Rosa, P.1
  • 139
    • 13444293534 scopus 로고    scopus 로고
    • The burgeoning molecular genetics of the Lyme disease spirochaete
    • Rosa, P. A., Tilly, K., and Stewart, P. E. (2005). The burgeoning molecular genetics of the Lyme disease spirochaete. Nat. Rev. Microbiol. 3, 129-143.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 129-143
    • Rosa, P.A.1    Tilly, K.2    Stewart, P.E.3
  • 141
    • 0034755831 scopus 로고    scopus 로고
    • Arthritis following recombinant outer surface protein A vaccination for Lyme disease
    • Rose, C. D., Fawcett, P. T., and Gibney, K. M. (2001). Arthritis following recombinant outer surface protein A vaccination for Lyme disease. J. Rheumatol. 28, 2555-2557.
    • (2001) J. Rheumatol. , vol.28 , pp. 2555-2557
    • Rose, C.D.1    Fawcett, P.T.2    Gibney, K.M.3
  • 142
    • 12844284086 scopus 로고    scopus 로고
    • Differential expression of Ixodes ricinus tick genes induced by blood feeding or Borrelia burgdorferi infection
    • Rudenko, N., Golovchenko, M., Edwards, M. J., and Grubhoffer, L. (2005). Differential expression of Ixodes ricinus tick genes induced by blood feeding or Borrelia burgdorferi infection. J. Med. Entomol. 42, 36-41.
    • (2005) J. Med. Entomol. , vol.42 , pp. 36-41
    • Rudenko, N.1    Golovchenko, M.2    Edwards, M.J.3    Grubhoffer, L.4
  • 143
    • 77649224507 scopus 로고    scopus 로고
    • Community ecology and disease risk: lizards, squirrels, and the Lyme disease spirochete in California, USA
    • Salkeld, D. J., and Lane, R. S. (2010). Community ecology and disease risk: lizards, squirrels, and the Lyme disease spirochete in California, USA. Ecology 91, 293-298.
    • (2010) Ecology , vol.91 , pp. 293-298
    • Salkeld, D.J.1    Lane, R.S.2
  • 144
    • 0036008681 scopus 로고    scopus 로고
    • A high affinity serotonin- and histamine-binding lipocalin from tick saliva
    • Sangamnatdej, S., Paesen, G. C., Slovak, M., and Nuttall, P. A. (2002). A high affinity serotonin- and histamine-binding lipocalin from tick saliva. Insect Mol. Biol. 11, 79-86.
    • (2002) Insect Mol. Biol. , vol.11 , pp. 79-86
    • Sangamnatdej, S.1    Paesen, G.C.2    Slovak, M.3    Nuttall, P.A.4
  • 145
    • 0003872504 scopus 로고
    • Morphology, Physiology, and Behavioral Biology of Ticks
    • Chichester; West Sussex; England; New York: E. Horwood; Halsted Press
    • Sauer, J. R., and Hair, J. A. (1986). Morphology, Physiology, and Behavioral Biology of Ticks. Chichester; West Sussex; England; New York: E. Horwood; Halsted Press.
    • (1986)
    • Sauer, J.R.1    Hair, J.A.2
  • 146
    • 32544450111 scopus 로고    scopus 로고
    • Protective efficacy of an oral vaccine to reduce carriage of Borrelia burgdorferi (strain N40) in mouse and tick reservoirs
    • Scheckelhoff, M. R., Telford, S. R., and Hu, L. T. (2006). Protective efficacy of an oral vaccine to reduce carriage of Borrelia burgdorferi (strain N40) in mouse and tick reservoirs. Vaccine 24, 1949-1957.
    • (2006) Vaccine , vol.24 , pp. 1949-1957
    • Scheckelhoff, M.R.1    Telford, S.R.2    Hu, L.T.3
  • 147
    • 0033220302 scopus 로고    scopus 로고
    • Infestation of Peromyscus leucopus and Tamias striatus by Ixodes scapularis (Acari: Ixodidae) in relation to the abundance of hosts and parasites
    • Schmidt, K. A., Ostfeld, R. S., and Schauber, E. M. (1999). Infestation of Peromyscus leucopus and Tamias striatus by Ixodes scapularis (Acari: Ixodidae) in relation to the abundance of hosts and parasites. J. Med. Entomol. 36, 749-757.
    • (1999) J. Med. Entomol. , vol.36 , pp. 749-757
    • Schmidt, K.A.1    Ostfeld, R.S.2    Schauber, E.M.3
  • 148
    • 33846867243 scopus 로고    scopus 로고
    • The paralogous salivary anti-complement proteins IRAC I and IRAC II encoded by Ixodes ricinus ticks have broad and complementary inhibitory activities against the complement of different host species
    • Schroeder, H., Daix, V., Gillet, L., Renauld, J. C., and Vanderplasschen, A. (2007). The paralogous salivary anti-complement proteins IRAC I and IRAC II encoded by Ixodes ricinus ticks have broad and complementary inhibitory activities against the complement of different host species. Microbes Infect. 9, 247-250.
    • (2007) Microbes Infect , vol.9 , pp. 247-250
    • Schroeder, H.1    Daix, V.2    Gillet, L.3    Renauld, J.C.4    Vanderplasschen, A.5
  • 149
    • 80051863283 scopus 로고    scopus 로고
    • A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent
    • Schuijt, T. J., Coumou, J., Narasimhan, S., Dai, J., Deponte, K., Wouters, D., et al. (2011a). A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent. Cell Host Microbe 10, 136-146.
    • (2011) Cell Host Microbe , vol.10 , pp. 136-146
    • Schuijt, T.J.1    Coumou, J.2    Narasimhan, S.3    Dai, J.4    Deponte, K.5    Wouters, D.6
  • 150
    • 79251546062 scopus 로고    scopus 로고
    • Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display
    • doi: 10.1371/journal.pone.0015926
    • Schuijt, T. J., Narasimhan, S., Daffre, S., Deponte, K., Hovius, J. W., Van't Veer, C., et al. (2011b). Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display. PLoS ONE [Electronic Resource] 6:e15926. doi: 10.1371/journal.pone.0015926
    • (2011) PLoS ONE [Electronic Resource] , vol.6
    • Schuijt, T.J.1    Narasimhan, S.2    Daffre, S.3    Deponte, K.4    Hovius, J.W.5    Van't Veer, C.6
  • 151
    • 46449119230 scopus 로고    scopus 로고
    • The tick salivary protein Salp15 inhibits the killing of serum-sensitive Borrelia burgdorferi sensu lato isolates
    • Schuijt, T. J., Hovius, J. W., Van Burgel, N. D., Ramamoorthi, N., Fikrig, E., and Van Dam, A. P. (2008). The tick salivary protein Salp15 inhibits the killing of serum-sensitive Borrelia burgdorferi sensu lato isolates. Infect. Immun. 76, 2888-2894.
    • (2008) Infect. Immun. , vol.76 , pp. 2888-2894
    • Schuijt, T.J.1    Hovius, J.W.2    Van Burgel, N.D.3    Ramamoorthi, N.4    Fikrig, E.5    Van Dam, A.P.6
  • 152
    • 84864769112 scopus 로고    scopus 로고
    • The role of cystatins in tick physiology and blood feeding
    • Schwarz, A., Valdes, J. J., and Kotsyfakis, M. (2012). The role of cystatins in tick physiology and blood feeding. Ticks Tick Borne Dis. 3, 117-127.
    • (2012) Ticks Tick Borne Dis , vol.3 , pp. 117-127
    • Schwarz, A.1    Valdes, J.J.2    Kotsyfakis, M.3
  • 153
    • 84863271309 scopus 로고    scopus 로고
    • Widespread dispersal of Borrelia burgdorferi-infected ticks collected from songbirds across Canada
    • Scott, J. D., Anderson, J. F., and Durden, L. A. (2012). Widespread dispersal of Borrelia burgdorferi-infected ticks collected from songbirds across Canada. J. Parasitol. 98, 49-59.
    • (2012) J. Parasitol. , vol.98 , pp. 49-59
    • Scott, J.D.1    Anderson, J.F.2    Durden, L.A.3
  • 154
    • 0027247886 scopus 로고
    • Cross-reactivity between B. burgdorferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs
    • Shin, S. J., Chang, Y.-F., Jacobson, R. H., Shaw, E., Lauderdale, T.-L., Appel, M. J., et al. (1993). Cross-reactivity between B. burgdorferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs. Vet. Microbiol. 36, 161-174.
    • (1993) Vet. Microbiol. , vol.36 , pp. 161-174
    • Shin, S.J.1    Chang, Y.-F.2    Jacobson, R.H.3    Shaw, E.4    Lauderdale, T.-L.5    Appel, M.J.6
  • 155
    • 0027230563 scopus 로고
    • Cross-reactivity between Borrelia burgdorferi flagellin and a human axonal 64,000 molecular weight protein
    • Sigal, L. H. (1993). Cross-reactivity between Borrelia burgdorferi flagellin and a human axonal 64, 000 molecular weight protein. J. Infect. Dis. 167, 1372-1378.
    • (1993) J. Infect. Dis. , vol.167 , pp. 1372-1378
    • Sigal, L.H.1
  • 156
    • 0004151015 scopus 로고
    • New York, NY: Oxford University Press
    • Sonenshine, D. E. (1991). Biology of Ticks. New York, NY: Oxford University Press.
    • (1991) Biology of Ticks
    • Sonenshine, D.E.1
  • 157
    • 79952721915 scopus 로고    scopus 로고
    • The expanding Lyme Borrelia complex-clinical significance of genomic species?
    • Stanek, G., and Reiter, M. (2011). The expanding Lyme Borrelia complex-clinical significance of genomic species? Clin. Microbiol. Infect. 17, 487-493.
    • (2011) Clin. Microbiol. Infect. , vol.17 , pp. 487-493
    • Stanek, G.1    Reiter, M.2
  • 158
    • 0032560841 scopus 로고    scopus 로고
    • Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group. [comment]
    • Steere, A. C., Sikand, V. K., Meurice, F., Parenti, D. L., Fikrig, E., Schoen, R. T., et al. (1998). Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group.[comment]. N. Engl. J. Med. 339, 209-215.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 209-215
    • Steere, A.C.1    Sikand, V.K.2    Meurice, F.3    Parenti, D.L.4    Fikrig, E.5    Schoen, R.T.6
  • 159
    • 68049093176 scopus 로고    scopus 로고
    • Tactics and economics of wildlife oral rabies vaccination, Canada and the United States
    • Sterner, R. T., Meltzer, M. I., Shwiff, S. A., and Slate, D. (2009). Tactics and economics of wildlife oral rabies vaccination, Canada and the United States. Emerg. Infect. Dis. 15, 1176-1184.
    • (2009) Emerg. Infect. Dis. , vol.15 , pp. 1176-1184
    • Sterner, R.T.1    Meltzer, M.I.2    Shwiff, S.A.3    Slate, D.4
  • 160
    • 0027292455 scopus 로고
    • Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines
    • Telford, S. R. 3rd., Fikrig, E., Barthold, S. W., Brunet, L. R., Spielman, A., and Flavell, R. A. (1993). Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines. J. Exp. Med. 178, 755-758.
    • (1993) J. Exp. Med. , vol.178 , pp. 755-758
    • Telford III, S.R.1    Fikrig, E.2    Barthold, S.W.3    Brunet, L.R.4    Spielman, A.5    Flavell, R.A.6
  • 162
    • 80052321988 scopus 로고    scopus 로고
    • Nest box-deployed bait for delivering oral vaccines to white-footed mice
    • Telford, S. R. I., Cunningham, J. A., Waltari, E., and Hu, L. (2011). Nest box-deployed bait for delivering oral vaccines to white-footed mice. Ticks Tick Borne Dis. 2, 151-155.
    • (2011) Ticks Tick Borne Dis , vol.2 , pp. 151-155
    • Telford, S.R.I.1    Cunningham, J.A.2    Waltari, E.3    Hu, L.4
  • 163
    • 33646930883 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection
    • Tilly, K., Krum, J. G., Bestor, A., Jewett, M. W., Grimm, D., Bueschel, D., et al. (2006). Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection. Infect. Immun. 74, 3554-3564.
    • (2006) Infect. Immun. , vol.74 , pp. 3554-3564
    • Tilly, K.1    Krum, J.G.2    Bestor, A.3    Jewett, M.W.4    Grimm, D.5    Bueschel, D.6
  • 164
    • 0003130910 scopus 로고
    • Accquired immunity to ticks
    • Trager, W. (1939). Accquired immunity to ticks. J. Parasitol. 25, 57-81.
    • (1939) J. Parasitol. , vol.25 , pp. 57-81
    • Trager, W.1
  • 165
    • 22244444464 scopus 로고    scopus 로고
    • A cross-reactive tick cement antigen is a candidate broad-spectrum tick vaccine
    • Trimnell, A. R., Davies, G. M., Lissina, O., Hails, R. S., and Nuttall, P. A. (2005). A cross-reactive tick cement antigen is a candidate broad-spectrum tick vaccine. Vaccine 23, 4329-4341.
    • (2005) Vaccine , vol.23 , pp. 4329-4341
    • Trimnell, A.R.1    Davies, G.M.2    Lissina, O.3    Hails, R.S.4    Nuttall, P.A.5
  • 166
    • 0035871803 scopus 로고    scopus 로고
    • Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1α L is a partial agonist for outer surface protein A-reactive T cells
    • Trollmo, C., Meyer, A. L., Steere, A. C., Hafler, D. A., and Huber, B. T. (2001). Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1α L is a partial agonist for outer surface protein A-reactive T cells. J. Immunol. 166, 5286-5291.
    • (2001) J. Immunol. , vol.166 , pp. 5286-5291
    • Trollmo, C.1    Meyer, A.L.2    Steere, A.C.3    Hafler, D.A.4    Huber, B.T.5
  • 167
    • 11144238722 scopus 로고    scopus 로고
    • An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle
    • Tsao, J. I., Wootton, J. T., Bunikis, J., Luna, M. G., Fish, D., and Barbour, A. G. (2004). An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle. Proc. Natl. Acad. Sci. U.S.A. 101, 18159-18164.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 18159-18164
    • Tsao, J.I.1    Wootton, J.T.2    Bunikis, J.3    Luna, M.G.4    Fish, D.5    Barbour, A.G.6
  • 168
    • 84864061791 scopus 로고    scopus 로고
    • Predicted outcomes of vaccinating wildlife to reduce human risk of lyme disease
    • Tsao, K., Fish, D., and Galvani, A. P. (2012). Predicted outcomes of vaccinating wildlife to reduce human risk of lyme disease. Vector Borne Zoonotic Dis. 12, 544-551.
    • (2012) Vector Borne Zoonotic Dis , vol.12 , pp. 544-551
    • Tsao, K.1    Fish, D.2    Galvani, A.P.3
  • 169
    • 34447619019 scopus 로고    scopus 로고
    • Biochemical and functional characterization of Salp20, an Ixodes scapularis tick salivary protein that inhibits the complement pathway
    • Tyson, K., Elkins, C., Patterson, H., Fikrig, E., and De Silva, A. (2007). Biochemical and functional characterization of Salp20, an Ixodes scapularis tick salivary protein that inhibits the complement pathway. Insect Mol. Biol. 16, 469-479.
    • (2007) Insect Mol. Biol. , vol.16 , pp. 469-479
    • Tyson, K.1    Elkins, C.2    Patterson, H.3    Fikrig, E.4    De Silva, A.5
  • 170
    • 0034705418 scopus 로고    scopus 로고
    • Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis
    • Valenzuela, J. G., Charlab, R., Mather, T. N., and Ribeiro, J. M. (2000). Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis. J. Biol. Chem. 275, 18717-18723.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18717-18723
    • Valenzuela, J.G.1    Charlab, R.2    Mather, T.N.3    Ribeiro, J.M.4
  • 171
    • 0030944136 scopus 로고    scopus 로고
    • Complement-mediated serum sensitivity among spirochetes that cause Lyme disease
    • Van Dam, A. P., Oei, A., Jaspars, R., Fijen, C., Wilske, B., Spanjaard, L., et al. (1997). Complement-mediated serum sensitivity among spirochetes that cause Lyme disease. Infect. Immun. 65, 1228-1236.
    • (1997) Infect. Immun. , vol.65 , pp. 1228-1236
    • Van Dam, A.P.1    Oei, A.2    Jaspars, R.3    Fijen, C.4    Wilske, B.5    Spanjaard, L.6
  • 172
    • 0030453699 scopus 로고    scopus 로고
    • Evaluation of the safety, reactogenicity and immunogenicity of three recombinant outer surface protein (OspA) lyme vaccines in healthy adults
    • Van Hoecke, C., Comberbach, M., De Grave, D., Desmons, P., Fu, D., Hauser, P., et al. (1996). Evaluation of the safety, reactogenicity and immunogenicity of three recombinant outer surface protein (OspA) lyme vaccines in healthy adults. Vaccine 14, 1620-1626.
    • (1996) Vaccine , vol.14 , pp. 1620-1626
    • Van Hoecke, C.1    Comberbach, M.2    De Grave, D.3    Desmons, P.4    Fu, D.5    Hauser, P.6
  • 173
    • 0024084105 scopus 로고
    • Immunological control of hematophagous arthropod vectors: utilization of novel antigens
    • Wikel, S. K. (1988). Immunological control of hematophagous arthropod vectors: utilization of novel antigens. Vet. Parasitol. 29, 235-264.
    • (1988) Vet. Parasitol. , vol.29 , pp. 235-264
    • Wikel, S.K.1
  • 174
    • 0030019155 scopus 로고    scopus 로고
    • Host immunity to ticks
    • Wikel, S. K. (1996). Host immunity to ticks. Annu. Rev. Entomol. 41, 1-22.
    • (1996) Annu. Rev. Entomol. , vol.41 , pp. 1-22
    • Wikel, S.K.1
  • 175
    • 0035935651 scopus 로고    scopus 로고
    • Progress toward molecular characterization of ectoparasite modulation of host immunity
    • Wikel, S. K., and Alarcon-Chaidez, F. J. (2001). Progress toward molecular characterization of ectoparasite modulation of host immunity. Vet. Parasitol. 101, 275-287.
    • (2001) Vet. Parasitol. , vol.101 , pp. 275-287
    • Wikel, S.K.1    Alarcon-Chaidez, F.J.2
  • 176
    • 0031014147 scopus 로고    scopus 로고
    • Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission of Borrelia burgdorferi by ticks
    • Wikel, S. K., Ramachandra, R. N., Bergman, D. K., Burkot, T. R., and Piesman, J. (1997). Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission of Borrelia burgdorferi by ticks. Infect. Immun. 65, 335-338.
    • (1997) Infect. Immun. , vol.65 , pp. 335-338
    • Wikel, S.K.1    Ramachandra, R.N.2    Bergman, D.K.3    Burkot, T.R.4    Piesman, J.5
  • 177
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang, X. F., Pal, U., Alani, S. M., Fikrig, E., and Norgard, M. V. (2004). Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J. Exp. Med. 199, 641-648.
    • (2004) J. Exp. Med. , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 178
    • 79959827638 scopus 로고    scopus 로고
    • Molecular interactions that enable movement of the Lyme disease agent from the tick gut into the hemolymph
    • doi: 10.1371/journal.ppat.1002079
    • Zhang, L., Zhang, Y., Adusumilli, S., Liu, L., Narasimhan, S., Dai, J., et al. (2011). Molecular interactions that enable movement of the Lyme disease agent from the tick gut into the hemolymph. PLoS Pathog. 7:e1002079. doi: 10.1371/journal.ppat.1002079
    • (2011) PLoS Pathog , vol.7
    • Zhang, L.1    Zhang, Y.2    Adusumilli, S.3    Liu, L.4    Narasimhan, S.5    Dai, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.