Complement-mediated serum sensitivity among spirochetes that cause Lyme disease

Infection and Immunity

Volumn 65, Issue 4, 1997, Pages 1228-1236

  Van Dam, Alje P ^a,c   Oei, Anneke ^a   Jaspars, Roeselien ^a,d   Fijen, Cees ^a   Wilske, Bettina ^b   Spanjaard, Lodewijk ^a   Dankert, Jacob ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF MUNICH   (Germany)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d ROYAL TROPICAL INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROPERDIN;

AGAMMAGLOBULINEMIA; ARTICLE; BACTERICIDAL ACTIVITY; BORRELIA BURGDORFERI; CELL KILLING; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMOBILIZED CELL; LYME DISEASE; PRIORITY JOURNAL; SEROTYPE; SPECIES DIFFERENTIATION; SPIROCHETE;

EID: 0030944136     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.4.1228-1236.1997     Document Type: Article

References (63)

1. Anthonissen, F. M., M. De Kesel, P. P. Hoet, and G. H. Bigaignon. 1994. Evidence for the involvement of different genospecies of Borrelia in the clinical outcome of Lyme disease in Belgium. Res. Microbiol. 145:327-331.
2. Assous, M. V., D. Postic, G. Paul, P. Névot, and G. Baranton. 1993. Western blot analysis of sera from Lyme borreliosis patients according to the genomic species of the Borrelia strains used as antigens. Eur. J. Clin. Microbiol. Infect. Dis. 12:261-268.
3. Aydintug, M. K., Y. Gu, and M. T. Philipp. 1994. Borrelia burgdorferi antigens that are targeted by antibody-dependent, complement-mediated killing in the rhesus monkey. Infect. Immun. 62:4929-4937.
4. Balmelli, T., and J.-C. Piffaretti. 1995. Association between different clinical manifestations of Lyme disease and different species of Borrelia burgdorferi sensu lato. Res. Microbiol. 146:329-340.
5. Barbour, A. G., R. A. Heiland, and T. R. Howe. 1985. Heterogeneity of major proteins in Lyme disease borreliae: a molecular analysis of North American and European isolates. J. Infect. Dis. 152:478-484.
6. Barthold, S. W., M. S. De Souza, J. L. Janotka, A. L. Smith, and D. H. Persing. 1993. Chronic Lyme borreliosis in the laboratory mouse. Am. J. Pathol. 143:959-971.
7. Benach, J. L., E. M. Bosler, J. P. Hanrahan, J. L. Coleman, G. S. Habicht, T. F. Bast, D. J. Cameron, J. L. Ziegler, A. G. Barbour, W. Burgdorfer, R. Edelman, and R. A. Kaslow. 1983. Spirochetes isolated from the blood of two patients with Lyme disease. N. Engl. J. Med. 308:740-742.
8. Bhakdi, S., W. Fassbender, F. Hugo, M.-P. Carreno, C. Berstecher, P. Malasit, and M. D. Kazatchkine. 1988. Relative inefficiency of terminal complement activation. J. Immunol. 141:3117-3122.
9. Bockenstedt, L. K., S. Barthold, K. Deponte, N. Marcantonio, and F. S. Kantor. 1993. Borrelia burgdorferi infection and immunity in mice deficient in the fifth component of complement. Infect. Immun. 61:2104-2107.
10. 9a.Brade, V. Personal communication.
11. Brade, V., I. Kleber, and G. Acker. 1992. Differences of two Borrelia burgdorferi strains in complement activation and serum resistance. Immunobiology 185:453-465.
12. Bredius, R. G. M., P. C. Driedijk, M. F. J. Schouten, R. S. Weening, and T. A. Out. 1992. Complement activation by polyclonal immunoglobulin G1 and G2 antibodies against Staphylococcus aureus, Haemophilus influenzae type b, and tetanus toxoid. Infect. Immun. 60:4838-4847.
13. Breitner-Ruddock, S., J. Schulze, and V. Brade, 1996. Borrelia burgdorferi genospecies differ in their reaction to the early immune system, abstr. F1020, p. 284. In VIIth International Congress on Lyme Borreliosis F2020.
14. Busth, U., C. Hizoteufel R. Boehmer, V. Fingerle, H. Nitschko, B. Wilske, and V. Preac-Mursic. 1996. Three species of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. afzelii, and B. garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR. J. Clin. Microbiol. 34:1072-1078.
15. Callister, S. M., R. F. Schell, and S. D. Lovrich. 1991. Lyme disease assay which detects killed Borrelia burgdorferi. J. Clin. Microbiol. 29:1773-1776.
16. Canica, M. M., F. Nato, L. Du Merie, J. C. Mazie, G. Baranton, and D. Postic. 1993. Monoclonal antibodies for identification of Borrelia afzelii sp. nov. associated with late cutaneous manifestations of Lyme borreliosis. Scand. J. Infect. Dis. 25:441-148.
17. Coleman, J. L., R. C. Rogers, and J. L. Benach. 1992. Selection of an escape variant of Borrelia burgdorferi by use of bactericidal monoclonal antibodies to OspB. Infect. Immun. 60:3098-3104.
18. Dever, L. L., J. H. Jorgensen, and A. G. Barbour. 1992. In vitro antimicrobial susceptibility testing of Borrelia burgdorferi: a microdilution MIC method and time-kill studies. J. Clin. Microbiol. 30:2692-2697.
19. Dressler, F., J. A. Whalen, B. N. Reinhardt, and A. C. Steere. 1993. Western blotting in the serodiagnosis of Lyme disease. J. Infect. Dis. 167:392-400.
20. Elkins, C., N. H. Carbonetti, V. A. Varela, D. Stirewalt, D. G. Klapper, and P. F. Sparling. 1992. Antibodies to N-terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylated. Mol. Microbiol. 6:2617-2628.
21. Fijen, C. A. P., R. Van den Boogaard, M. R. Dana, J. Dankert, M. Mannens, and E. J. Kuijper. 1996. Carrier detection by microsatellite haplotyping in 10 properdin type-1 deficient families. Eur. J. Clin. Invest. 26:902-906.
22. Fikrig, E., L. K. Bockenstedt, S. W. Barthold, M. Chen, H. Tao, P. Ali-Salaam, S. R. Telford, and R. A. Flavell. 1994. Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis. J. Infect. Dis. 169:568-574.
23. Fitzgerald, T. J. 1987. Activation of the classical and alternative pathways of complement by Treponema pallidum subsp. pallidum and Treponema vincentii. Infect. Immun. 55:2066-2073.
24. Hauptmann, G., E. Grosshans, and E. Heid. 1974. Lupus érythémateux aigus et déficits héréditaires en complément. A propos d'un cas par déficit complet en C4. Ann. Dermatol. Syphiligr. 101:479-496.
25. Kochi, S. K., and R. C. Johnson. 1988. Role of immunoglobulin G in killing of Borrelia burgdorferi by the classical complement pathway. Infect. Immun. 56:314-321.
26. Kolb, W. P., L. M. Kolb, and E. R. Podack. 1979. C1q: isolation from human serum in high yield by affinity chromatography and development of a highly sensitive hemolytic assay. J. Immunol. 122:2103-2111.
27. Kornblatt, A. N., A. C. Steere, and D. G. Brownstein. 1984. Experimental Lyme disease in rabbits: spirochetes found in erythema migrans and in blood. Infect. Immun. 46:220-223.
28. Kuiper, H., P. P. Devriese, B. M. De Jongh, K. Vos, and J. Dankert. 1992. Absence of Lyme borreliosis among patients with presumed Bell's palsy. Arch. Neurol. 49:940-943.
29. Kuiper, H., A. P. Van Dam, A. W. Moll van Charante, A. P. Nauta, and J. Dankert. 1993. One year follow-up study to assess the prevalence and incidence of Lyme borreliosis among Dutch forestry workers. Eur. J. Clin. Microbiol. Infect. Dis. 12:413-418.
30. Loos, M., and F. Clas. 1987. Antibody-independent killing of Gram-negative bacteria via the classical pathway of complement. Immunol. Lett. 14:203-211.
31. Lovrich, S. D., S. M. Callister, J. L. Schmitz, J. D. Alder, and R. F. Schell. 1991. Borreliacidal activity of sera from hamsters infected with the Lyme disease spirochete. Infect. Immun. 59:2522-2528.
32. Marconi, R. T., and C. F. Garon. 1992. Development of polymerase chain reaction primer sets for diagnosis of Lyme disease and for species-specific identification of Lyme disease isolates by 16S rRNA signature nucleotide analysis. J. Clin. Microbiol. 30:2830-2834.
33. Merino, S., S. Camprubi, S. Alberti, V. J. Benedi, and J. M. Tomas. 1992. Mechanisms of Klebsiella pneumoniae resistance to complement-mediated killing. Infect. Immun. 60:2529-2535.
34. Moskophidis, M., and B. Luther. 1993. Monoclonal antibodies with in vitro borrelicidal activity define the outer surface proteins A and B of Borrelia burgdorferi. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 279:201-213.
35. Nadelman, R. B., C. S. Pavia, L. A. Magnarelli, and G. P. Wormser. 1990. Isolation of Borrelia burgdorferi from the blood of seven patients with Lyme disease. Am. J. Med. 88:21-26.
36. Nadelman, R. B., I. Schwartz, and G. P. Wormser. 1994. Detecting Borrelia burgdorferi in blood from patients with Lyme disease. J. Infect. Dis. 169:1410-1411.
37. Nohlmans, L. M. K. E., R. De Boer, A. E. J. M. Van Den Bogaard, and C. P. A. Van Boven. 1995. Genotypic and phenotypic analysis of Borrelia burgdorferi isolates from The Netherlands. J. Clin. Microbiol. 33:119-125.
38. Pachner, A. R., E. Delaney, T. O'Neill, and E. Major. 1995. Inoculation of nonhuman primates with the N40 strain of Borrelia burgdorferi leads to a model of Lyme neuroborreliosis faithful to the human disease. Neurology 45:165-172.
39. Pavia, C. S., V. Kissel, S. Bittker, F. Cabello, and S. Levine. 1991. Antiborrelial activity of serum from rats injected with the Lyme disease spirochete. J. Infect. Dis. 163:656-659.
40. Peter, O., and A. G. Bretz. 1942. Polymorphism of outer surface proteins of Borrelia burgdorferi as a tool for classification. Int. J. Med. Microbiol. Virol. Parasitol. Infect. Dis. 277:28-33.
41. Péter, O., A.-G. Bretz, R. Zenhäusern, H. Roten, and E. Roulet. 1993. Isolement de Borrelia burgdorferi du liquide céphalorachidin de trois enfants avec une atteinte neurologique. Schweiz. Med. Wochenschr. 123:14-19.
42. Philipp, M. T., M. K. Aydintug, R. P. Bohm, Jr., F. B. Cogswell, V. A. Dennis, H. N. Lanners, R. C. Lowrie, Jr., E. D. Roberts, M. D. Conway, M. Karaçorlu, G. A. Peyman, D. J. Gubler, B. J. B. Johnson, J. Piesman, and Y. Gu. 1993. Early and early disseminated phases of Lyme disease in the rhesus monkey: a model for infection in humans. Infect. Immun. 61:3047-3059.
43. Postic, D., M. V. Assous, P. A. D. Grimont, and G. Baranton. 1994. Diversity of Borrelia burgdorferi sensu lato evidenced by restriction fragment length polymorphism of rrf (5S)-rrl (23S) intergenic spacer amplicons. Int. J. Syst. Bacteriol. 44:743-752.
44. Preac-Mursic, V., B. Wilske, and G. Schierz. 1986. European Borrelia burgdorferi isolated from humans and ticks: culture conditions and antibiotic susceptibility. Zentralbl. Bakteriol. A 263:112-118.
45. Rijpkema, S. G. T., M. J. C. H. Molkenboer, L. M. Schouls, F. Jongejan, and J. F. P. Schellekens. 1995. Simultaneous detection and genotyping of three genomic groups of Borrelia burgdorferi sensu lato in Dutch Ixodes ricinus ticks by characterization of the amplified intergenic spacer region between 5S and 23S rRNA genes. J. Clin. Microbiol. 33:3091-3095.
46. Rosa, P. A., T. G. Schwan, and D. Hogan. 1992. Recombination between genes encoding major outer membrane proteins A and B of Borrelia burgdorferi. Mol. Microbiol. 6:3031-3040.
47. Sadziene, A., A. G. Barbour, P. A. Rosa, and D. D. Thomas. 1993. An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo. Infect. Immun. 61:3590-3596.
48. Sadziene, A., P. A. Rosa, P. A. Thompson, D. M. Hogan, and A. G. Barbour. 1992. Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. J. Exp. Med. 176:799-809.
49. Sadziene, A., D. D. Thomas, and A. G. Barbour. 1995. Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization. Infect. Immun. 63:1573-1580.
50. Sadziene, A., P. A. Thompson, and A. G. Barbour. 1993. In vitro inhibition of Borrelia burgdorferi growth by antibodies. J. Infect. Dis. 167:165-172.
51. Schmitz, J. L., S. D. Lovrich, S. M. Callister, and R. F. Schell. 1991. Depletion of complement and effects on passive transfer of resistance to infection with Borrelia burgdorferi. Infect. Immun. 59:3815-3818.
52. Schwan, T. G., W. Burgdorfer, and C. F. Garon. 1988. Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect. Immun. 56:1831-1836.
53. Scriba, M., J. S. Ebrahim, T. Schlott, and H. Eiffert. 1993. The 39-kilodalton protein of Borrelia burgdorferi: a target for bactericidal human monoclonal antibodies. Infect. Immun. 61:4523-4526.
54. Shoberg, R. J., M. Jonsson, A. Sadziene, S. Bergström, and D. D. Thomas. 1994. Identification of a highly cross-reactive outer surface protein B epitope among diverse geographic isolates of Borrelia spp. causing Lyme disease. J. Clin. Microbiol. 32:489-500.
55. Steere, A. C. 1989. Lyme disease. N. Engl. J. Med. 321:586-596.
56. Tenner, A. J., R. J. Ziccardi, and N. R. Cooper. 1984. Antibody-independent C1 activation by E. coli. J. Immunol. 133:886-891.
57. Truedsson, L., A. G. Sjöholm, and A. B. Laurell. 1981. Screening for deficiencies in the classical and alternative pathway by hemolysis in gel. APMIS 89:161-166.
58. Van Dam, A. P., H. Kuiper, K. Vos, A. Widjojokusumo, L. Spanjaard, B. M. De Jongh, A. C. P. Ramselaar, M. D. Kramer, and J. Dankert. 1993. Different genospecies of Borrelia burgdorferi are associated with distinct clinical manifestations in Lyme borreliosis. Clin. Infect. Dis. 17:708-717.
59. Viljanen, M. K., J. Oksi, P. Salomaa, M. Skurnik, R. Peltonen, and H. Kalimo. 1992. Cultivation of Borrelia burgdorferi from the blood and a subcutaneous lesion of a patient with relapsing febrile nodular nonsuppurative panniculitis. J. Infect. Dis. 165:596-597.
60. Wetzler, L. M., K. Barry, M. S. Blake, and E. C. Gotschlich. 1992. Gonococcal lipooligosaccharide sialylation prevents complement activation by immune sera. Infect. Immun. 60:39-43.
61. Whicher, J. T., J. Higginson, P. G. Riches, and S. Radford. 1980. Clinical applications of immunofixation: detection and quantitation of complement activation. J. Clin. Pathol. 33:781-785.
62. Wienecke, R., N. Zöchling, U. Neubert, E.-M. Schlüpen, M. Meurer, and M. Volkenandt. 1994. Molecular subtyping of Borrelia burgdorferi in erythema migrans and acrodermatitis chronica atrophicans. J. Invest. Dermatol. 103:19-22.
63. Wilske, B., V. Preac-Mursic, U. B. Göbel, B. Graf, S. Jauris, E. Soutschek, E. Schwab, and G. Zumstein. 1993. An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis. J. Clin. Microbiol. 31:340-350.