Exploring the mialome of ticks: An annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae)

BMC Genomics

Volumn 9, Issue , 2008, Pages

  Anderson, Jennifer M ^a   Sonenshine, Daniel E ^b   Valenzuela, Jesus G ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b OLD DOMINION UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IRON; MEMBRANE ANTIGEN; MUCIN;

ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DERMACENTOR; DETOXIFICATION; DIGESTIVE SYSTEM; DNA LIBRARY; EXPRESSED SEQUENCE TAG; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC IDENTIFICATION; INSECT GENETICS; IRON METABOLISM; IRON TRANSPORT; MIDGUT; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; SEQUENCE ANALYSIS; UNINDEXED SEQUENCE; AMINO ACID SEQUENCE; ANIMAL; DNA SEQUENCE; ENZYMOLOGY; GASTROINTESTINAL TRACT; GENE EXPRESSION PROFILING; GENE LIBRARY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; SEQUENCE ALIGNMENT;

ACARI; DERMACENTOR VARIABILIS; IXODIDA; IXODIDAE;

AMINO ACID SEQUENCE; ANIMALS; DERMACENTOR; EXPRESSED SEQUENCE TAGS; FEMALE; GASTROINTESTINAL TRACT; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE LIBRARY; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 60849099047     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-9-552     Document Type: Article

References (105)

1. Fogaca AC da Silva PI Jr Miranda MT Bianchi AG Miranda A Ribolla PE Daffre S Antimicrobial activity of a bovine hemoglobin fragment in the tick Boophilus microplus J Biol Chem 1999, 274:25330-25334 10464258
2. Nakajima Y Ogihara K Taylor D Yamakawa M Antibacterial hemoglobin fragments from the midgut of the soft tick, Ornithodoros moubata (Acari: Argasidae) J Med Entomol 2003, 40:78-81 12597657
3. Sonenshine DE Hynes WL Ceraul SM Mitchell R Benzine T Host blood proteins and peptides in the midgut of the tick Dermacentor variabilis contribute to bacterial control Exp Appl Acarol 2005, 36:207-223 16132735
4. Nakajima Y Goes van Naters-Yasui van der A Taylor D Yamakawa M Antibacterial peptide defensin is involved in midgut immunity of the soft tick, Ornithodoros moubata Insect Mol Biol 2002 ,11:611-618 12421419
5. Kopacek P Vogt R Jindrak L Weise C Safarik I Purification and characterization of the lysozyme from the gut of the soft tick Ornithodoros moubata Insect Biochem Mol Biol 1999, 29(11):989-997 10560138
6. Haddow JD Haines LR Gooding RH Olafson RW Pearson TW Identification of midgut proteins that are differentially expressed in trypanosome-susceptible and normal tsetse flies (Glossina morsitans morsitans) Insect Biochem Mol Biol 2005, 35:425-433 15804576
7. Jahan N Docherty PT Billingsly PF Hurd H Blood digestion in the mosquito, Anopheles stephensi: The effects of Plasmodium yoelii nigeriensis on midgut enzyme activities Parasitology 1999, 119:535-541 10633914
8. Jiang Q Hall M Noriega FG Wells M cDNA cloning and pattern of expression of an adult, female-specific chymotrypsin from Aedes aegypti midgut Insect Biochem Mol Biol 1997, 27:283-289 9134710
9. Ramalho-Ortigao M Jochim RC Anderson JM Lawyer PG Pham VM Kamhawi S Valenzuela JG Exploring the midgut transcriptome of Phlebotomus papatasi: Comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected sandflies BMC Genomics 2007, 8:300 2034597 17760985
10. Lara FA Lins U Paiva-Silva G Almeida IC Braga CM Miguens FC Oliveira PL Dansa-Petretski M A new intracellular pathway of haem detoxification in the midgut of the cattle tick Boophilus microplus: Aggregation inside a specialized organelle, the haemosome J Exp Biol 2003, 206:1707-1715 12682102
11. Lara FA Lins U Bechara GH Oliveira PL Tracing heme in a living cell: hemoglobin degradation and heme traffic in digest cells of the cattle tick Boophilus microplus J Exp Biol 2005, 208:3093-3101 16081607
12. Graca-Souza A Maya-Monteiro C Paiva-Silva GO Braz GR Paes MC Sorgine MH Oliveira MF Oliveira PL Adaptations against heme toxicity in blood-feeding arthropods Insect Biochem Mol Biol 2006, 36:322-335 16551546
13. Agyei ADHI Runham NW Histochemical localization of acid phosphatase and non-specific esterase in the midguts of two species of tick, Boophilus microplus and Rhipicephalus appendiculatus, as determined by light microscopy Parasitology Research 1991, 77(7):629-634 1724321
14. Gough JM Kemp DH Acid phosphatase in midgut digestive cells in partially fed females of the cattle tick, Boophilus microplus Journal of Parasitology 1995, 81(3):341-349 7776118
15. Renard G Lara FA de Cardoso FC Miguens FC Dansa-Petretski M Termignoni C Masuda A Expression and immunolocalization of a Boophilus microplus cathepsins L-like enzyme Insect Mol Biol 2002, 11:325-328 12144697
16. Mulenga A Misao O Sugimoto C Three serine proteinases from midguts of the hard tick Rhipicephalus appendiculatus; cDNA cloning and preliminary characterization Exp Appl Acarol 2003, 29(1-2):151-164 14580067
17. Miyoshi T Tsuji N Islam MK Kamio T Fujisaki K Cloning and molecular characterization of a cubilin-related serine proteinase from the hard tick Haemaphysalis longicornis Insect Biochem Mol Biol 2004, 34:799-808 15262284
18. Altschul SF Madden TL Schaffer AA Zhang J Zhang Z Miller W Lipman DJ Gapped BLAST and PSI-BLAST: A new generation of protein database search programs Nucleic Acids Res 1997, 25:3389-3402 146917 9254694
19. Ashburner M Ball CA Blake JA Botstein D Butler H Cherry JM Davis AP Dolinski K Dwight SS Eppig JT Harris MA Hill DP Issel-Tarver L Kasarskis A Lewis S Matese JC Richardson JE Ringwald M Rubin GM Sherlock G Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium Nat Genet 2000, 25:25-29 10802651
20. Marchler-Bauer A Panchenko AR Shoemaker BA Thiessen PA Geer LY Bryant SH CDD: A database of conserved domain alignments with links to domain three-dimensional structure Nucleic Acids Res 2002, 30:281-283 99109 11752315
21. Bendtsen JD Nielsen H von Heijne G Brunak S Improved prediction of signal peptides: SignalP 3.0 J Mol Biol 2004, 340(4):783-795 15223320
22. Emanuelsson O Brunak S von Heijne G Nielsen H Locating proteins in the cell using TargetP, SignalP, and related tools Nature Protocols 2007, 2:953-971 17446895
23. Sheehan DGM Foley VM Dowd CA Structure, function and evolution of glutathione transferases: Implications for classification of non-mammalian members of an ancient enzyme superfamily Biochem J 2001, 360(Pt 1):1-16 1222196 11695986
24. Dreher-Lesnick SM Mulenga A Simser JA Azad AF Differential expression of two glutathione S-transferases identified from the American dog tick, Dermacentor variabilis Insect Mol Biol 2006, 15(4):445-453 16907831
25. Jakoksson PJ Morgenstern R Mancini J Ford-Hutchinson A Persson B Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily Am J Respir Crit Care Med 2000, 161:S20-24 10673221
26. Bresell A Weinander R Lundqvist G Raza H Shimoji M Sun TH Balk L Wiklund R Eriksson J Jansson C Persson B Jakobsson PJ Morgenstern R Bioinformatic and enzymatic characterization of the MAPEG superfamily FEBS J 2005, 272(7):1688-1703 15794756
27. Corona M Robinson GE Genes of the antioxidant system of the honey bee: annotation and phylogeny Insect Mol Biol 2006, 15:687-701 1847502 17069640
28. Xu Y Bruno JF Luft BJ Identification of novel tick salivary gland proteins for vaccine development Biochem Biophys Res Commun 2005, 326:901-904 15607754
29. Nishinaka H Nakamura H Yodoi J Thioredoxin cytokine response Methods Enzymol 2002, 347:332-338 11898424
30. Ursini F Maiorino M Brigelius-Flohé R Aumann KD Roveri A Schomburg D Flohé L Diversity of glutathione peroxidases Methods Enzymol 1995, 252:38-53 7476373
31. Cossio-Bayugar R Miranda E Holman PJ Molecular cloning of a phospholipid-hydroperoxide glutathione peroxidase gene from the tick, Boophilus microplus (Acari: Ixodidae) Insect Biochem Mol Biol 2005, 35:1378-1387 16291093
32. Battistoni A Role of prokaryotic Cu, Zn superoxide dismutase in pathogenesis Biochem Soc Trans 2003, 31(Pt 6):1326-1329 14641055
33. Choi YS Lee KS Yoon HJ Kim I Sohn HD Jin BR Bombus ignitus Cu, Zn superoxide dismutase (SOD1): CDNA cloning, gene structure, and up-regulation in response to paraquat, temperature stress, or lipopolysaccharide stimulation Comp Biochem Physiol B Biochem Mol Biol 2006, 144:365-371 16730205
34. Pacello F Langford PR Kroll JS Indiani C Smulevich G Desideri A Rotilio G Battistoni A A novel heme protein, the Cu, Zn-superoxide dismutase from Haemophilus ducreyi J Biol Chem 2001, 276:30326-30334 11369755
35. Negari S Sulpher J Pacello F Ingrey K Battistoni A Lee BC A role for Haemophilus ducreyi Cu, Zn SOD in resistance to heme toxicity Biometals 2007 17704897
36. Rubin H Serine protease inhibitors (SERPINS): Where mechanism meets medicine Nat Med 1996, 2:632-633 8640547
37. Kanost MR Serine proteinase inhibitors in arthropod immunity Dev Comp Immunol 1999, 23:291-301 10426423
38. Mulenga A Khumthong R Blandon MA Molecular and expression analysis of a family of the Amblyomma americanum tick: Lospins J Exp Biol 2007, 210(Pt 18):3188-3198 17766296
39. Ricci CG Berger M Termignoni C A thrombin inhibitor from the gut of Boophilus microplus ticks Exp Appl Acarol 2007, 42:291-300 17710557
40. Lai R Takeuchi H Jonczy J Rees HH Turner PC A thrombin inhibitor from the ixodid tick, Amblyomma hebraeum Gene 2004, 342:243-249 15527983
41. Locht van de A Stubbs MT Bode W Friedrich T Bollschweiler C Höffken W Huber R The ornithodorin-thrombin crystal structure, a key to the TAP enigma? EMBO J 1996, 15:6011-6017 452422 8947023
42. Mans BJ Louw AI Neitz AW Amino acid sequence and structure modeling of savignin, a thrombin inhibitor from the tick, Ornithodoros savignyi Insect Biochem Mol Biol 2002, 32:821-828 12044499
43. Grunclova L Horn M Vancova M Sojka D Franta Z Mares M Kopacek P Two secreted cystatins of the soft tick Ornithodoros moubata: Differential expression pattern and inhibitory specificity Biol Chem 2006, 387;1635-1644 17132111
44. Bode W Engh R Musil D Thiele U Huber R Karshikov A Brzin J Kos J Turk V The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases EMBO J 1988, 7:2593-2599 457133 3191914
45. Abrahamson M Alvarez-Ferandez M Nathanson CM Cystatins Biochem Soc Symp 2003, 70:179-199 14587292
46. Akov S Blood digestion in ticks Oxford: Pergamon Press 1982
47. Motobu M Tsuji N Miyoshi T Huang X Islam MK Alim MA Fujisaki K Molecular characterization of a blood-induced serine carboxypeptidase from the ixodid tick Haemaphysalis longicornis FEBS J 2007, 274:3299-3312 17542992
48. Sharma A Eapen A Subbarao SK Purification and Characterization of a hemoglobin degrading aspartic protease from the malarial parasite Plasmodium vivax J Biochem 2005, 138:71-78 16046450
49. Hamilton KA Nisbet AJ Lehane MJ Taylor MA Billingsley PF A physiological and biochemical model for digestion in the ectoparasitic mite, Psoroptes ovis (Acari: Psoroptidae) Int J Parasitol 2003, 33(8):773-785 12865077
50. Sojka D Hajdusek O Dvorak J Sajid M Franta Z Schneider EL Craik CS IrAE: an asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus Int J Parasitol 2007, 37:713-724 2587490 17336985
51. Abdul-Alim M Tsuji N Miyoshi T Khyrul IM Huang X Motobu M Fujisaki K Characterization of asparaginyl endopeptidase, legumain induced by blood feeding in the ixodid tick Haemaphysalis longicornis Insect Biochem Mol Biol 2007, 37:911-922 17681230
52. Wang P Granados RR Molecular structure of the peritrophic membrane (PM): Identification of potential PM target sites for insect control Arch Insect Biochem Physiol 2001, 47:110-117 11376457
53. Sorgine MH Logullo C Zingali RB Paiva-Silva GO Juliano L Oliveira PL A heme-binding aspartic proteinase from the eggs of the hard tick Boophilus microplus J BiolChem 2000, 275:28659-28665
54. Boldbaatar D Sikasunge CS Battsetseg B Xuan X Fujisaki K Molecular cloning and functional characterization of an aspartic protease from the hard tick Haemaphysalis longicornis Insect Biochem Mol Biol 2006, 36:25-36 16360947
55. Manoury B Mazzeo D Li DN Billson J Loak K Benaroch P Watts C Motobu M Tsuji N Miyoshi T Huang X Islam MK Alim MA Fujisaki K Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone Immunity 2003, 18:489-498 12705852
56. Dalton JP Clough KA Jones MK Brindley PJ The cysteine proteinases of Schistosoma mansoni cercariae Parasitology 1997 114 (Pt 2):105-112 9051919
57. Grigor'eva LA Amosoa LI Peritrophic matrix in the midgut of tick females of the genus Ixodes (Acari: Ixodidae) Parazitologia 2004 ,38:3-11 15069874
58. Zhu Z Gern L Aeschlimann A The peritrophic membrane of Ixodes ricinus Parasitol Res 1991, 77:635-641 1792236
59. Matsuo T Sato M Inoue N Yokayam N Taylor D Fujisaki K Morphological studies on the extracellular structure of the midgut of a tick, Haemaphysalis longicornis (Acari: Ixodidae) Parasitol Res 2003, 90:243-248 12783315
60. Bishop R Lambson B Wells C Pandit P Osaso J Nkonge C Morzaria S Musoke A Nene V A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle Int J Parasitol 2002, 32:833-842 12062554
61. Riding GA Jarmey J McKenna RV Pearson R Cobon GS Willadsen P A protective "concealed" antigen from Boophilus microplus. Purification, localization, and possible function J Immunol 1994, 153:5158-5166 7963573
62. Pau U Li X Wang T Montgomery RR Ramamoorthy N DeSilva AM Bao F Yang X Pypaert M Pradhan D Kantor FS Telford S Anderson JF Fikrig E TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi Cell 2004, 119:457-468 15537536
63. Rudenko N Golovchenko M Edwards MJ Grubhoffer L Differential expression of Ixodes ricinus tick genes induced by blood feeding or Borrelia burgdorfer i infection J Med Entomol 2005, 42:36-41 15691006
64. Phillips SE Vincent P Rizzieri KE Schaaf G Bankaitis VA Gaucher EA The Diverse Biological Functions of Phosphatidylinositol Transfer Proteins in Eukaryotes Crit Rev Biochem Mol Biol 2006, 41(1):21-49 16455519
65. Kovar V Kopacek P Grubhoffer L Isolation and characterization of Dorin M, a lectin from plasma of the soft tick Ornithodoros moubata Insect Biochem Mol Biol 2000, 30:195-205 10732987
66. Rego ROM Koar V Kopacek P Weise C Man P Sauman Ivo Grubhoffer L The tick plasma lectin, Dorin M, is a fibrinogen-related molecule Insect Biochem Mol Biol 2006, 36:291-299 16551543
67. Rego RO Hajdusek O Kovar V Kopacek P Grubhoffer L Hypsa V Molecular cloning and comparative analysis of fibrinogen-related proteins from the soft tick Ornithodoros moubata and the hard tick Ixodes ricinus Insect Biochem Mol Biol 2005, 35:991-1004 15979000
68. Gillespie JP Kanost MR Trenczek T Biological mediators of insect immunity Annu Rev Entomol 1997, 42:611-643 9017902
69. Mulenga A Sugimoto C Onuma M Characterization of proteolytic enzymes expressed in the midgut of Haemaphysalis longicornis Japanese Journal of Veterinary Research 1999, 46(4):179-184 10414026
70. Geiser DL Zhang D Winzerling JJ Secreted ferritin: Mosquito defense against iron overload? Insect Biochem Mol Biol 2006, 36:177-187 16503479
71. Mulenga A Simser JA Macaluso KR Azad AF Stress and transcriptional regulation of tick ferritin HC Insect Mol Biol 2004, 13:423-433 15271215
72. Coons LB Rosell-Davies E Tarnowski BI Bloodmeal digestion in ticks Morphology, Physiology and Behavioral Biology of Ticks Chichester: Ellis Horwood Sauer JR, Hair JA 1986 1
73. Rosell R Coons LB The role of the fat body, midgut and ovary in vitellogenin production and vitellogenesis in the female tick, Dermacentor variabilis Int J Parasitol 1992, 22(3):341-349 1639570
74. Sugino M Imamura S Mulenga A Nakajima M Tsuda A ohashi K Onuma M A serine proteinase inhibitor (serpin) from ixodid tick Haemaphysalis longicornis; cloning and preliminary assessment of its suitability as a candidate for a tick vaccine Vaccine 2003, 21:2844-2851 12798626
75. Zhou J Ueda M Umemiya R Battsetseg B Boldbaatar D Xuan X Fujisaki K A secreted cystatin from the tick Haemaphysalis longicornis and its distinct expression patterns in relation to innate immunity Insect Biochem Mol Biol 2006, 36:527-535 16835018
76. Shi L Paskewitz SM Proteomics and insect immunity Invert Surv J 2006, 3:4-17
77. Ribeiro JCM Alarcon-Chaidez F Francischetti IMB Mans BJ Mather TN Valenzuela JG Wikel SK An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks Insect Biochem Mol Biol 2006, 36:111-129 16431279
78. Valenzuela JG Francischetti JM Pham VM Garfield MK Mather TN Ribeiro JM Exploring the sialome of the tick Ixodes scapularis J Exp Biol 2002, 205:2843-2864 12177149
79. Mendiola J Alonso M Marquetti MC Finlay C Boophilus microplus: Multiple proteolytic activities in the midgut Exp Parasitol 1996, 82:27-33 8617328
80. Kocan KM Yoshioka J Sonenshine DE de la Fuente J Ceraul SM Blouin EF Almazan C A capillary tube feeding system for studying tick/pathogen interactions of Dermacentor variabilis (Acari: Ixodidae) and Anaplasma marginale (Rickettsiales: Anaplasmataceae) J Med Entomol 2005, 42:864-874 16366000
81. Sonenshine DE Ceraul SM Hynes WL Macaluso KR Azad AF Expression of defensin-like peptides in tick hemolymph and midgut in response to challenge with Borrelia burgdorferi, Escherischia coli and Bacillus subtilis Exp Appl Acarol 2002, 28:127-134 14570122
82. Willot E Tran HQ Zinc and Manduca sexta hemocyte functions J Insect Sci 2002, 2:6 355906 15455040
83. Ceraul SM Dreher-Lesnick SM Gillespie JJ Rahman MS Azad AF New tick defensin isoform and antimicrobial gene expression in response to Rickettsia montanensis challenge Infect Immun 2007, 75:1973-1983 1865714 17261604
84. Sonenshine DE The Biology of Ticks Oxford University Press 1993, 2
85. Valenzuela JG Charlab R Gonzales EC de Miranda-Santos IK Marinotti O Francischetti IM Ribeiro JM The D7 family of salivary proteins in blood sucking diptera Insect Mol Biol 2002, 11:149-155 11966880
86. Mulenga A Tsuda A Onuma M Sugimoto C Four serine protease inhibitors (serpin) from the brown ear tick, Rhipicephalus appendiculatus; cDNA cloning and preliminary characterization Insect Biochem Mol Biol 2003, 33(2):267-276 12535684
87. Simser JA Macaluso KR Mulenga A Azad AF Immune-responsive lysozymes from hemocytes of the American dog tick, Dermacentor variabilis and an embryonic cell line of the Rocky Mountain wood tick, D. andersoni Insect Biochem Mol Biol 2004, 34(12):1235-1246 15544937
88. Grunclova L Fouguier H Hypga V Kopacek P Lysozyme from the gut of the soft tick, Ornithodoros moubata, the sequence, phylogeny and post-feeding regulation Dev Comp Immunol 2003, 27(8):651-660 12798362
89. Hamilton JV Munks RJ Lehane SM Lehane MJ Association of midgut defensin with a novel serine protease in the blood-sucking fly Stomoxys calcitrans Insect Mol Biol 2002, 11:197-205 12000638
90. Matsuo T Okoda Y Badgar B Inoue N Xuan X Taylor D Fujisaki K Fate of GFP-expressing Escherischia coli in the midgut and response to ingestion in a tick, Ornithodoros moubata (Acari: Argasidae) Exp Parasitol 2004, 108:67-73 15491551
91. FTP directory /blast/executables/ ftp://ftp.ncbi.nih.gov/blast/ executables/
92. Huang X Madan A CAP3: A DNA sequence assembly program Genome Res 1999, 9:868-877 310812 10508846
93. Lewis S Ashburner M Reese MG Annotating eukaryote genomes Curr Opin Struct Biol 2000, 10:349-354 10851187
94. Tatusov RL Fedorova ND Jackson JD Jacobs AR Kiryutin B Koonin EV Krylov DM Mazmuder R Mekhedov SI Nikolskaya AN Rao BS Smirnov S Sverdlov A Vasudevan S Wolf YI Yin JJ Natale DA The COG database: An updated version includes eukaryotes BMC Bioinformatics 2003, 4:41 222959 12969510
95. Bateman A Birney E Durbin R Eddy SR Howe KL Sonnhammer EL The Pfam protein families database Nucleic Acids Res 2000, 28:263-266 102420 10592242
96. Schulze J Copley RR Doerks T Ponting CP Bork P SMART: A web-based tool for the study of genetically mobile domains Nucleic Acid Res 2000, 28:231-234 102444 10592234
97. Nielsen H Englebrecht J Brunak S von Heijne G Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites Protein Eng 1997, 10:1-6 9051728
98. Thompson JD Gibson TJ Plewniak F Jeanmougin F Higgins DG The ClustalX windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools Nucleic Acids Res 1997, 25:4876-4882 147148 9396791
99. BioEdit http://www.mbio.ncsu.edu/BioEdit/page2.html
100. Abascal F Zardoya R Posada D ProtTest: Selection of best-fit models of protein evolution Bioinformatics 2005, 21:2104-2105 15647292
101. Schmidt HA Strimmer K Vingron M von Haeseler A TREE-PUZZLE: Maximum likelihood phylogenetic analysis using quartets and parallel computing Bioinformatics 2002, 18:502-504 11934758
102. Felsenstein J Estimation of hominoid phylogeny from a DNA hybridization data set J Mol Evol 1987, 26:123-131 3125330
103. Tamura KJD Nei M Kumar S MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0 Mol Biol Evol 2007, 24(8):1596-1599 17488738
104. Transcriptomes of vector arthropods and non-vector, medically important arthropods http://exon.niaid.nih.gov/transcriptome
105. Han ZS Ip YT Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression J Biol Chem 1999, 274:21355-21361 10409696