Probing functional properties of nociceptive axons using a microfluidic culture system

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Tsantoulas, Christoforos ^a,b   Farmer, Clare ^a,b   Machado, Patricia ^a,b   Baba, Katsuhiro ^b   McMahon, Stephen B ^a   Raouf, Ramin ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; NEUROTROPHIN; SODIUM CHANNEL NAV1.8; CALCIUM; CAPSAICIN; SODIUM CHANNEL BLOCKING AGENT; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; KERATINOCYTE; MALE; MICROFLUIDIC ANALYSIS; MOLECULAR IMAGING; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL LESION; NERVE CELL MEMBRANE POTENTIAL; NERVE CONDUCTION; NERVE FIBER; NERVE REGENERATION; NOCICEPTION; NONHUMAN; PATCH CLAMP TECHNIQUE; ACTION POTENTIAL; ANIMAL; BIOASSAY; BIOLOGICAL MODEL; C57BL MOUSE; CELL COMMUNICATION; CELL CULTURE; COCULTURE; CYTOLOGY; DEVICES; DRUG EFFECTS; ELECTROSTIMULATION; METABOLISM; MICROFLUIDICS; NERVE FIBER TRANSECTION; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SENSORY NERVE CELL; SPINAL GANGLION; SYNAPTIC TRANSMISSION; WISTAR RAT;

ACTION POTENTIALS; ANIMALS; AXONS; AXOTOMY; BIOLOGICAL ASSAY; CALCIUM; CAPSAICIN; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ELECTRIC STIMULATION; FEMALE; GANGLIA, SPINAL; KERATINOCYTES; MALE; MICE, INBRED C57BL; MICROFLUIDICS; MODELS, BIOLOGICAL; NERVE GROWTH FACTOR; NOCICEPTION; PATCH-CLAMP TECHNIQUES; RATS, WISTAR; SENSORY RECEPTOR CELLS; SODIUM CHANNEL BLOCKERS; SYNAPTIC TRANSMISSION; TRPV CATION CHANNELS;

EID: 84894253037     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080722     Document Type: Article

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