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Volumn 101, Issue 1, 2014, Pages 114-124

Interpreting estrogen screening assays in the context of potency and human exposure relative to natural exposures to phytoestrogens

Author keywords

Biomonitoring; Endocrine disruption; Risk assessment

Indexed keywords

BIOLOGICAL MARKER; PHYTOESTROGEN;

EID: 84894232007     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.21085     Document Type: Article
Times cited : (7)

References (57)
  • 1
    • 47549116949 scopus 로고    scopus 로고
    • Biomonitoring equivalents (BE) dossier for 2,4-dichlorophenoxyacetic acid (2,4-D) (CAS No. 94-75-7)
    • Aylward LL, Hays SM. 2008. Biomonitoring equivalents (BE) dossier for 2, 4-dichlorophenoxyacetic acid (2, 4-D) (CAS No. 94-75-7). Regul Toxicol Pharmacol 51(3 Suppl):S37-S48.
    • (2008) Regul Toxicol Pharmacol , vol.51 , Issue.3 SUPPL.
    • Aylward, L.L.1    Hays, S.M.2
  • 2
    • 81455132854 scopus 로고    scopus 로고
    • Consideration of dosimetry in evaluation of ToxCast™ data
    • Aylward LL, Hays SM. 2011. Consideration of dosimetry in evaluation of ToxCast™ data. J Appl Toxicol. 31(8):741-751.
    • (2011) J Appl Toxicol. , vol.31 , Issue.8 , pp. 741-751
    • Aylward, L.L.1    Hays, S.M.2
  • 3
    • 80052422340 scopus 로고    scopus 로고
    • Assessment of margin of exposure based on biomarkers in blood: an exploratory analysis
    • Aylward LL, Becker RA, Kirman CR, Hays SM. 2011. Assessment of margin of exposure based on biomarkers in blood: an exploratory analysis. Regul Toxicol Pharmacol 61:44-52.
    • (2011) Regul Toxicol Pharmacol , vol.61 , pp. 44-52
    • Aylward, L.L.1    Becker, R.A.2    Kirman, C.R.3    Hays, S.M.4
  • 4
    • 84874631279 scopus 로고    scopus 로고
    • Evaluation of biomonitoring data from the CDC National Exposure Report in a risk assessment context: perspectives across chemicals
    • Aylward LL, Kirman CR, Schoeny R, Portier CJ, Hays SM. 2013. Evaluation of biomonitoring data from the CDC National Exposure Report in a risk assessment context: perspectives across chemicals. Environ Health Perspect 121:287-294.
    • (2013) Environ Health Perspect , vol.121 , pp. 287-294
    • Aylward, L.L.1    Kirman, C.R.2    Schoeny, R.3    Portier, C.J.4    Hays, S.M.5
  • 7
    • 0034463175 scopus 로고    scopus 로고
    • Comparative assessment of endocrine modulators with oestrogenic activity: I. Definition of a hygiene-based margin of safety (HBMOS) for xeno-oestrogens against the background of European developments
    • Bolt HM, Janning P, Michna H, Degen GH. 2001. Comparative assessment of endocrine modulators with oestrogenic activity: I. Definition of a hygiene-based margin of safety (HBMOS) for xeno-oestrogens against the background of European developments. Arch Toxicol 74(11):649-662.
    • (2001) Arch Toxicol , vol.74 , Issue.11 , pp. 649-662
    • Bolt, H.M.1    Janning, P.2    Michna, H.3    Degen, G.H.4
  • 8
    • 0038353644 scopus 로고    scopus 로고
    • A critical review of methods for comparing estrogenic activity of endogenous and exogenous chemicals in human milk and infant formula
    • Borgert CJ, LaKind JS, Witorsch RJ. 2003. A critical review of methods for comparing estrogenic activity of endogenous and exogenous chemicals in human milk and infant formula. Environ Health Perspect 111(8):1020-1036.
    • (2003) Environ Health Perspect , vol.111 , Issue.8 , pp. 1020-1036
    • Borgert, C.J.1    LaKind, J.S.2    Witorsch, R.J.3
  • 9
    • 79952696156 scopus 로고    scopus 로고
    • Evaluation of EPA's Tier 1 endocrine screening battery and recommendations for improving the interpretation of screening results
    • Borgert CJ, Mihaich EM, Quill TF, Marty MS, Levine SL, Becker RA. 2011a. Evaluation of EPA's Tier 1 endocrine screening battery and recommendations for improving the interpretation of screening results. Regul Toxicol Pharmacol. 59:397-411.
    • (2011) Regul Toxicol Pharmacol. , vol.59 , pp. 397-411
    • Borgert, C.J.1    Mihaich, E.M.2    Quill, T.F.3    Marty, M.S.4    Levine, S.L.5    Becker, R.A.6
  • 15
    • 84894288622 scopus 로고    scopus 로고
    • CDC. Laboratory procedure manual, analyte: benzophenone-3, bisphenol A, 2,4-dichlorophenol, 2,5-dichlorophenol, ortho-phenylphenol, methyl-, ethyl-, propyl-, and butyl parabens, 4-tertoctylphenol, 2,4,5-trichlorophenol, 2,4,6- trichlorophenol, triclosan, Matrix: Urine, Method No: 6301.01. Available at: Accessed Nov. 25. 2013.
    • CDC. 2009. Laboratory procedure manual, analyte: benzophenone-3, bisphenol A, 2, 4-dichlorophenol, 2, 5-dichlorophenol, ortho-phenylphenol, methyl-, ethyl-, propyl-, and butyl parabens, 4-tertoctylphenol, 2, 4, 5-trichlorophenol, 2, 4, 6- trichlorophenol, triclosan, Matrix: Urine, Method No: 6301.01. Available at: http://www. cdc.gov/nchs/data/nhanes/nhanes_05_06/eph_d_met_phenols_ parabens.pdf. Accessed Nov. 25. 2013.
    • (2009)
  • 16
    • 84894288691 scopus 로고    scopus 로고
    • CDC. Fourth National Report on Human Exposure to Environmental Chemicals, updated tables, March, 2013. Available at: Accessed Nov. 25. 2013.
    • CDC. 2013. Fourth National Report on Human Exposure to Environmental Chemicals, updated tables, March, 2013. Available at: http://www.cdc.gov/exposurereport/pdf/FourthReport_UpdatedTables_Mar2013.pdf. Accessed Nov. 25. 2013.
    • (2013)
  • 18
    • 0034194657 scopus 로고    scopus 로고
    • Ability of xeno- and phytoestrogens to modulate expression of estrogen-sensitive genes in rat uterus: estrogenicity profiles and uterotropic activity
    • Diel P, Schulz T, Smolnikar K, Strunck E, Vollmer G, Michna H. 2000. Ability of xeno- and phytoestrogens to modulate expression of estrogen-sensitive genes in rat uterus: estrogenicity profiles and uterotropic activity. J Steroid Biochem Mol Biol 73(1-2):1-10.
    • (2000) J Steroid Biochem Mol Biol , vol.73 , Issue.1-2 , pp. 1-10
    • Diel, P.1    Schulz, T.2    Smolnikar, K.3    Strunck, E.4    Vollmer, G.5    Michna, H.6
  • 19
    • 61449097026 scopus 로고    scopus 로고
    • EFSA panel on contaminants in the food chain: glucosinolates as undesirable substances in animal feed. Scientific Panel on Contaminants in the Food Chain
    • EFSA.
    • EFSA. 2008. EFSA panel on contaminants in the food chain: glucosinolates as undesirable substances in animal feed. Scientific Panel on Contaminants in the Food Chain. EFSA J 590:1-76.
    • (2008) EFSA J , vol.590 , pp. 1-76
  • 20
    • 84894246999 scopus 로고    scopus 로고
    • EPA, EDSTAC final report, chapter three, conceptual framework and principles. Page 3-16. Available at: Accessed Nov. 25, 2013.
    • EPA. 1998. EDSTAC final report, chapter three, conceptual framework and principles. Page 3-16. Available at: http://www.epa.gov/endo/pubs/edstac/chap3v14.pdf. Accessed Nov. 25, 2013.
    • (1998)
  • 21
    • 84894286129 scopus 로고    scopus 로고
    • EPA, Endocrine Disruptor Screening Program Test Guidelines, OPPTS 890.1600: uterotrophic assay. Available at: Accessed Nov. 25, 2013.
    • EPA. 2009. Endocrine Disruptor Screening Program Test Guidelines, OPPTS 890.1600: uterotrophic assay. Available at: http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/series890.htm. Accessed Nov. 25, 2013.
    • (2009)
  • 22
    • 84894225057 scopus 로고    scopus 로고
    • EPA, Endocrine disruptor screening program, weight-of-evidence: evaluating results of EDSP Tier 1 screening to identify the need for Tier 2 testing. Available at: Accessed Nov. 25, 2013.
    • EPA. 2011. Endocrine disruptor screening program, weight-of-evidence: evaluating results of EDSP Tier 1 screening to identify the need for Tier 2 testing. Available at: http://www.epa.gov/endo/. Accessed Nov. 25, 2013.
    • (2011)
  • 23
    • 84894245958 scopus 로고    scopus 로고
    • EPA, Benchmark dose technical guidance. Available at: Accessed Nov. 25, 2013.
    • EPA. 2012a. Benchmark dose technical guidance. Available at: http://www.epa.gov/raf/publications/pdfs/benchmark_ dose_guidance.pdf. Accessed Nov. 25, 2013.
    • (2012)
  • 24
    • 84894280537 scopus 로고    scopus 로고
    • EPA, EPA 2012. TSCA workplan chemical risk assessment, N-methylpyrrolidone: paint stripping use. December 2012. Available at: Accessed Nov. 25, 2013.
    • EPA. 2012b. EPA 2012. TSCA workplan chemical risk assessment, N-methylpyrrolidone: paint stripping use. December 2012. Available at: http://www.epa.gov/oppt/existingchemicals/pubs/TSCA_ Workplan_Chemical_Risk_Assessment_of_NMP.pdf. Accessed Nov. 25, 2013.
    • (2012)
  • 25
    • 84894259964 scopus 로고    scopus 로고
    • EPA, Endocrine Disruptor Screening Program (EDSP). Available at: Accessed Nov. 25, 2013.
    • EPA. 2013a. Endocrine Disruptor Screening Program (EDSP). Available at: http://www.epa.gov/endo/index.htm. Accessed Nov. 25, 2013.
    • (2013)
  • 26
    • 84894227017 scopus 로고    scopus 로고
    • EPA, Series 890-endocrine disruptor screening program test guidelines. Available at: Accessed Nov. 25, 2013.
    • EPA. 2013b. Series 890-endocrine disruptor screening program test guidelines. Available at: http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/series890.htm. Accessed Nov. 25, 2013.
    • (2013)
  • 27
    • 84894245877 scopus 로고    scopus 로고
    • EPA, Overview of the second list of chemicals for Tier 1 screening. Accessed Nov. 25, 2013.
    • EPA. 2013b. Overview of the second list of chemicals for Tier 1 screening. http://www.epa.gov/endo/pubs/prioritysetting/list2facts.htm. Accessed Nov. 25, 2013.
    • (2013)
  • 28
    • 84894235467 scopus 로고    scopus 로고
    • EPF. Endocrine Policy Forum comments on "Endocrine Disruptor Screening Program (EDSP) Evaluation of Tier 1 Screening Assays and Battery Performance, May 20, 2013." Available at: Accessed November 25, 2013.
    • EPF. 2013a. Endocrine Policy Forum comments on "Endocrine Disruptor Screening Program (EDSP) Evaluation of Tier 1 Screening Assays and Battery Performance, May 20, 2013." Available at: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPP-2013-0075-0013. Accessed November 25, 2013.
    • (2013)
  • 29
    • 84894255948 scopus 로고    scopus 로고
    • EPF. Endocrine policy forum comments on weight-of-evidence: evaluating results of the EDSP Tier 1 screening. Available at: Accessed Nov. 25, 2013.
    • EPF. 2013b. Endocrine policy forum comments on weight-of-evidence: evaluating results of the EDSP Tier 1 screening. Available at: http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPP-2013-0230-0011. Accessed Nov. 25, 2013.
    • (2013)
  • 30
    • 33751084895 scopus 로고    scopus 로고
    • Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective
    • Hays SM, Becker RA, Leung HW, Aylward LL, Pyatt DW. 2007. Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective. Regul Toxicol Pharmacol 47(1):96-109.
    • (2007) Regul Toxicol Pharmacol , vol.47 , Issue.1 , pp. 96-109
    • Hays, S.M.1    Becker, R.A.2    Leung, H.W.3    Aylward, L.L.4    Pyatt, D.W.5
  • 31
    • 47549112161 scopus 로고    scopus 로고
    • Guidelines for the derivation of biomonitoring equivalents: report from the Biomonitoring Equivalents Expert Workshop
    • Hays SM, Aylward LL, LaKind JS, Bartels MJ, Barton HA, Boogaard PJ, et al. 2008. Guidelines for the derivation of biomonitoring equivalents: report from the Biomonitoring Equivalents Expert Workshop. Regul Toxicol Pharmacol 51(3 Suppl):S4-S15.
    • (2008) Regul Toxicol Pharmacol , vol.51 , Issue.3 SUPPL.
    • Hays, S.M.1    Aylward, L.L.2    LaKind, J.S.3    Bartels, M.J.4    Barton, H.A.5    Boogaard, P.J.6
  • 33
    • 0034811778 scopus 로고    scopus 로고
    • The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: phase 1
    • Kanno J, Onyon L, Haseman J, Fenner-Crisp P, Ashby J, Owens W. 2001. The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: phase 1. Environ Health Perspect 109(8):785-794.
    • (2001) Environ Health Perspect , vol.109 , Issue.8 , pp. 785-794
    • Kanno, J.1    Onyon, L.2    Haseman, J.3    Fenner-Crisp, P.4    Ashby, J.5    Owens, W.6
  • 34
    • 0141451919 scopus 로고    scopus 로고
    • The OECD program to validate the rat uterotrophic bioassay. Phase 2: coded single-dose studies
    • Kanno J, Onyon L, Peddada S, Ashby J, Jacob E, Owens W. 2003. The OECD program to validate the rat uterotrophic bioassay. Phase 2: coded single-dose studies. Environ Health Perspect 111(12):1550-1558.
    • (2003) Environ Health Perspect , vol.111 , Issue.12 , pp. 1550-1558
    • Kanno, J.1    Onyon, L.2    Peddada, S.3    Ashby, J.4    Jacob, E.5    Owens, W.6
  • 36
    • 84877152770 scopus 로고    scopus 로고
    • Pleiotropic preventive effects of dietary polyphenols in cardiovascular diseases
    • Kishimoto Y, Tani M, Kondo K. 2013. Pleiotropic preventive effects of dietary polyphenols in cardiovascular diseases. Eur J Clin Nutr 67(5):532-535.
    • (2013) Eur J Clin Nutr , vol.67 , Issue.5 , pp. 532-535
    • Kishimoto, Y.1    Tani, M.2    Kondo, K.3
  • 38
    • 0036309574 scopus 로고    scopus 로고
    • Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model
    • Krul C, Humblot C, Philippe C, Vermeulen M, van Nuenen M, Havenaar R, Rabot S. 2002. Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model. Carcinogenesis 23:1009-1016.
    • (2002) Carcinogenesis , vol.23 , pp. 1009-1016
    • Krul, C.1    Humblot, C.2    Philippe, C.3    Vermeulen, M.4    van Nuenen, M.5    Havenaar, R.6    Rabot, S.7
  • 39
    • 0038418500 scopus 로고    scopus 로고
    • Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells
    • Le H, Schaldach CM, Firestone GL, Bjeldanes LF. (2003). Plant-derived 3, 3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 2278:21136-21145
    • (2003) J Biol Chem , vol.2278 , pp. 21136-21145
    • Le, H.1    Schaldach, C.M.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 40
    • 84984421596 scopus 로고
    • Effects of 5-vinyloxazolidine-2-thione on lactating rats and their sucklings
    • Lewerenz H-J, Bleyl DWR, Schnaak W. 1992. Effects of 5-vinyloxazolidine-2-thione on lactating rats and their sucklings. Nahrung 36:388-393.
    • (1992) Nahrung , vol.36 , pp. 388-393
    • Lewerenz, H.-J.1    Bleyl, D.W.R.2    Schnaak, W.3
  • 41
    • 84894240276 scopus 로고    scopus 로고
    • OECD, OECD Guideline for the Testing of Chemicals. Uterotrophic bioassay in rodents: a short-term screening test for oestrogenic properties. Available at: Accessed Nov. 25, 2013.
    • OECD. 2007. OECD Guideline for the Testing of Chemicals. Uterotrophic bioassay in rodents: a short-term screening test for oestrogenic properties. Available at: http://www.epa.gov/endo/pubs/uterotrophic_OECD_guideline.pdf. Accessed Nov. 25, 2013.
    • (2007)
  • 42
    • 84894265075 scopus 로고    scopus 로고
    • OECD, Series on testing and assessment: testing for endocrine disrupters. Available at: Accessed Nov. 25, 2013.
    • OECD. 2013a. Series on testing and assessment: testing for endocrine disrupters. Available at: http://www.oecd.org/chemicalsafety/testing/seriesontestingandassessmenttestingforendocrinedisrupters.htm. Accessed Nov. 25, 2013.
    • (2013)
  • 43
    • 84894264302 scopus 로고    scopus 로고
    • OECD, OECD guidelines for the testing of chemicals; Section 4, health effects and Section 2, effects on biotic systems. Available at: Accessed Nov. 25, 2013.
    • OECD. 2013b. OECD guidelines for the testing of chemicals; Section 4, health effects and Section 2, effects on biotic systems. Available at: http://www.oecd.org/env/ehs/testing/oecdguidelinesforthetestingofchemicals.htm. Accessed Nov. 25, 2013.
    • (2013)
  • 46
    • 79959819051 scopus 로고    scopus 로고
    • Maximum cumulative ratio (MCR) as a tool for assessing the value of performing a cumulative risk assessment
    • Price PS, Han X. 2011. Maximum cumulative ratio (MCR) as a tool for assessing the value of performing a cumulative risk assessment. Int J Environ Res Public Health 8(6):2212-2225.
    • (2011) Int J Environ Res Public Health , vol.8 , Issue.6 , pp. 2212-2225
    • Price, P.S.1    Han, X.2
  • 47
    • 34248652109 scopus 로고    scopus 로고
    • Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized rats
    • Rachon D, Vortherms T, Seidlova-Wuttke D, Wuttke W. 2007. Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized rats. Maturitas 57(2):161-170.
    • (2007) Maturitas , vol.57 , Issue.2 , pp. 161-170
    • Rachon, D.1    Vortherms, T.2    Seidlova-Wuttke, D.3    Wuttke, W.4
  • 50
    • 84858711810 scopus 로고    scopus 로고
    • Toxicokinetics and lack of uterotropic effect of orally administered S-equol
    • Schwen RJ, Nguyen L, Plomley JB, Jackson RL. 2012. Toxicokinetics and lack of uterotropic effect of orally administered S-equol. Food Chem Toxicol 50(5):1741-1748.
    • (2012) Food Chem Toxicol , vol.50 , Issue.5 , pp. 1741-1748
    • Schwen, R.J.1    Nguyen, L.2    Plomley, J.B.3    Jackson, R.L.4
  • 51
    • 80052315921 scopus 로고    scopus 로고
    • Twenty-four hour human urine and serum profiles of bisphenol a during high-dietary exposure
    • Teeguarden JG, Calafat AM, Ye X, Doerge DR, Churchwell MI, Gunawan R, et al. 2011. Twenty-four hour human urine and serum profiles of bisphenol a during high-dietary exposure. Toxicol Sci 123(1):48-57.
    • (2011) Toxicol Sci , vol.123 , Issue.1 , pp. 48-57
    • Teeguarden, J.G.1    Calafat, A.M.2    Ye, X.3    Doerge, D.R.4    Churchwell, M.I.5    Gunawan, R.6
  • 52
    • 0032116898 scopus 로고    scopus 로고
    • Clinical Review 97. Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence
    • Available at: Accessed Nov. 25, 2013.
    • Tham DM, Gardner CD, Haskell WL. 1998. Clinical Review 97. Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab 83(7):2223-35. Available at: http://jcem.endojournals.org/content/83/7/2223.long. Accessed Nov. 25, 2013.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.7 , pp. 2223-2235
    • Tham, D.M.1    Gardner, C.D.2    Haskell, W.L.3
  • 53
    • 27544473491 scopus 로고    scopus 로고
    • Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry
    • Tham DM, Gardner CD, Haskell WL, Volkel W, Bittner N, Dekant W. 2005. Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry. Drug Metab Dispos 33(11):1748-1757.
    • (2005) Drug Metab Dispos , vol.33 , Issue.11 , pp. 1748-1757
    • Tham, D.M.1    Gardner, C.D.2    Haskell, W.L.3    Volkel, W.4    Bittner, N.5    Dekant, W.6
  • 54
    • 45849092540 scopus 로고    scopus 로고
    • Determination of free and total bisphenol A in human urine to assess daily uptake as a basis for a valid risk assessment
    • Tinwell H, Colombel S, Blanck O, Bars R, Volkel W, Kiranoglu M, Fromme H. 2008. Determination of free and total bisphenol A in human urine to assess daily uptake as a basis for a valid risk assessment. Toxicol Lett 179(3):155-162.
    • (2008) Toxicol Lett , vol.179 , Issue.3 , pp. 155-162
    • Tinwell, H.1    Colombel, S.2    Blanck, O.3    Bars, R.4    Volkel, W.5    Kiranoglu, M.6    Fromme, H.7
  • 55
    • 84877654978 scopus 로고    scopus 로고
    • The screening of everyday life chemicals in validated assays targeting the pituitary-gonadal axis
    • Tinwell H, Colombel S, Blanck O, Bars R. 2013. The screening of everyday life chemicals in validated assays targeting the pituitary-gonadal axis. Regul Toxicol Pharmacol. 66:184-196.
    • (2013) Regul Toxicol Pharmacol. , vol.66 , pp. 184-196
    • Tinwell, H.1    Colombel, S.2    Blanck, O.3    Bars, R.4


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