Toxicokinetics and lack of uterotropic effect of orally administered S-equol

Food and Chemical Toxicology

Volumn 50, Issue 5, 2012, Pages 1741-1748

  Schwen, Richard J ^a   Nguyen, Linh ^b   Plomley, Jeffrey B ^b   Jackson, Richard L ^a  

^a Ausio Pharmaceuticals LLC   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

Author keywords

Cytochrome P450; Metabolism; Protein binding; S equol; Toxicokinetics; Uterotropic effect

Indexed keywords

CYTOCHROME P450; NATURAL PRODUCT; S EQUOL; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; ENZYME INDUCTION; FEMALE; HAPLORHINI; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MORPHOLOGY; NONHUMAN; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; TOXICITY TESTING; TOXICOKINETICS; UTERUS WEIGHT;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BLOOD PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; EQUOL; FEMALE; MACACA FASCICULARIS; MALE; MICROSOMES, LIVER; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; UTERUS;

ANIMALIA; MACACA FASCICULARIS; RATTUS;

EID: 84858711810     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.02.039     Document Type: Article

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