메뉴 건너뛰기




Volumn 74, Issue 4, 2014, Pages 1116-1127

CRR9/CLPTM1L regulates cell survival signaling and is required for ras transformation and lung tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; GENES, RAS; HEK293 CELLS; HUMANS; LUNG NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NIH 3T3 CELLS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84894226710     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1617     Document Type: Article
Times cited : (56)

References (45)
  • 1
    • 0034805276 scopus 로고    scopus 로고
    • A novelgene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis
    • Yamamoto K, Okamoto A, Isonishi S, Ochiai K, Ohtake Y. A novelgene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis. Biochem Biophys Res Commun 2001;280:1148-54.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 1148-1154
    • Yamamoto, K.1    Okamoto, A.2    Isonishi, S.3    Ochiai, K.4    Ohtake, Y.5
  • 2
    • 84861899749 scopus 로고    scopus 로고
    • Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus
    • James MA, Wen W, Wang Y, Byers LA, Heymach JV, Coombes KR, et al. Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. PLoS One 2012;7: e36116.
    • (2012) PLoS One , vol.7
    • James, M.A.1    Wen, W.2    Wang, Y.3    Byers, L.A.4    Heymach, J.V.5    Coombes, K.R.6
  • 3
    • 84871586597 scopus 로고    scopus 로고
    • CLPTM1L is overexpressed in lung cancer and associated with apoptosis
    • Ni Z, Tao K, Chen G, Chen Q, Tang J, Luo X, et al. CLPTM1L is overexpressed in lung cancer and associated with apoptosis. PLoS One 2012;7:e52598.
    • (2012) PLoS One , vol.7
    • Ni, Z.1    Tao, K.2    Chen, G.3    Chen, Q.4    Tang, J.5    Luo, X.6
  • 4
    • 0034352334 scopus 로고    scopus 로고
    • Regulation of Bcl-xL: A little bit of this and a little bit of STAT
    • Grad JM, Zeng X-R, Boise LH. Regulation of Bcl-xL: a little bit of this and a little bit of STAT. Curr Opin Oncol 2000;12:543-9.
    • (2000) Curr Opin Oncol , vol.12 , pp. 543-549
    • Grad, J.M.1    Zeng, X.-R.2    Boise, L.H.3
  • 5
    • 77954237882 scopus 로고    scopus 로고
    • Network organization of the human autophagy system
    • Behrends C, Sowa ME, Gygi SP, Harper JW. Network organization of the human autophagy system. Nature 2010;466:68-76.
    • (2010) Nature , vol.466 , pp. 68-76
    • Behrends, C.1    Sowa, M.E.2    Gygi, S.P.3    Harper, J.W.4
  • 6
    • 77949452524 scopus 로고    scopus 로고
    • The PKB/AKT pathway in cancer
    • Carnero A. The PKB/AKT pathway in cancer. Curr Pharm Des 2010;16: 34-44.
    • (2010) Curr Pharm des , vol.16 , pp. 34-44
    • Carnero, A.1
  • 7
    • 0033621956 scopus 로고    scopus 로고
    • The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
    • Chen C, Edelstein LC, Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol 2000;20:2687-95.
    • (2000) Mol Cell Biol , vol.20 , pp. 2687-2695
    • Chen, C.1    Edelstein, L.C.2    Gelinas, C.3
  • 8
    • 84862652571 scopus 로고    scopus 로고
    • Multiple variants of TERT and CLPTM1L constitute risk factors for lung ade-nocarcinoma
    • Chen XF, Cai S, Chen QG, Ni ZH, Tang JH, Xu DW, et al. Multiple variants of TERT and CLPTM1L constitute risk factors for lung ade-nocarcinoma. Genet Mol Res 2012;11:370-8.
    • (2012) Genet Mol Res , vol.11 , pp. 370-378
    • Chen, X.F.1    Cai, S.2    Chen, Q.G.3    Zh, N.4    Tang, J.H.5    Xu, D.W.6
  • 9
    • 80053166661 scopus 로고    scopus 로고
    • Novelgenetic variants in the chromosome 5p15.33 region associate with lung cancer risk
    • Pande M, Spitz MR, Wu X, Gorlov IP, Chen WV, Amos CI. Novelgenetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis 2011;32:1493-9.
    • (2011) Carcinogenesis , vol.32 , pp. 1493-1499
    • Pande, M.1    Spitz, M.R.2    Wu, X.3    Gorlov, I.P.4    Chen, W.V.5    Amos, C.I.6
  • 10
    • 84867142061 scopus 로고    scopus 로고
    • Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population
    • Wang S, Wu J, Hu L, Ding C, Kan Y, Shen Y, et al. Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population. Mol Carcinog 2012;51 Suppl 1:E118-22.
    • (2012) Mol Carcinog , vol.51 , Issue.SUPPL. 1
    • Wang, S.1    Wu, J.2    Hu, L.3    Ding, C.4    Kan, Y.5    Shen, Y.6
  • 13
    • 77649188501 scopus 로고    scopus 로고
    • A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33
    • Petersen GM, Amundadottir L, Fuchs CS, Kraft P, Stolzenberg-Sol-omon RZ, Jacobs KB, et al. A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet 2010;42:224-8.
    • (2010) Nat Genet , vol.42 , pp. 224-228
    • Petersen, G.M.1    Amundadottir, L.2    Fuchs, C.S.3    Kraft, P.4    Stolzenberg-Sol-Omon, R.Z.5    Jacobs, K.B.6
  • 14
    • 84947899485 scopus 로고    scopus 로고
    • A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
    • Rothman N, Garcia-Closas M, Chatterjee N, Malats N, Wu X, Figueroa JD, et al. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet 2010;42: 978-84.
    • (2010) Nat Genet , vol.42 , pp. 978-984
    • Rothman, N.1    Garcia-Closas, M.2    Chatterjee, N.3    Malats, N.4    Wu, X.5    Figueroa, J.D.6
  • 15
    • 72149129508 scopus 로고    scopus 로고
    • A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
    • Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 2009;85:679-91.
    • (2009) Am J Hum Genet , vol.85 , pp. 679-691
    • Landi, M.T.1    Chatterjee, N.2    Yu, K.3    Goldin, L.R.4    Goldstein, A.M.5    Rotunno, M.6
  • 16
    • 84864471078 scopus 로고    scopus 로고
    • Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population
    • Zhao Y, Chen G, Song X, Chen H, Mao Y, Lu D. Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population. Int J Cancer 2012; 131:1569-76.
    • (2012) Int J Cancer , vol.131 , pp. 1569-1576
    • Zhao, Y.1    Chen, G.2    Song, X.3    Chen, H.4    Mao, Y.5    Lu, D.6
  • 18
    • 84870622476 scopus 로고    scopus 로고
    • TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: Evidence from a meta-analysis based on 29 publications
    • Yin J, Li Y, Yin M, Sun J, Liu L, Qin Q, et al. TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications. PLoS One 2012;7: e50650.
    • (2012) PLoS One , vol.7
    • Yin, J.1    Li, Y.2    Yin, M.3    Sun, J.4    Liu, L.5    Qin, Q.6
  • 20
    • 40049087659 scopus 로고    scopus 로고
    • Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
    • Kang JU, Koo SH, Kwon KC, Park JW, Kim JM. Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet Cytogenet 2008;182:1-11.
    • (2008) Cancer Genet Cytogenet , vol.182 , pp. 1-11
    • Kang, J.U.1    Koo, S.H.2    Kwon, K.C.3    Park, J.W.4    Kim, J.M.5
  • 21
    • 84868156549 scopus 로고    scopus 로고
    • Influence of common genetic variation on lung cancer risk: Meta-analysis of 14 900 cases and 29 485 controls
    • Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeboller H, et al. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet 2012;21:4980-95.
    • (2012) Hum Mol Genet , vol.21 , pp. 4980-4995
    • Timofeeva, M.N.1    Hung, R.J.2    Rafnar, T.3    Christiani, D.C.4    Field, J.K.5    Bickeboller, H.6
  • 23
    • 0029909822 scopus 로고    scopus 로고
    • Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells
    • Herzog CR, Soloff EV, McDoniels AL, Tyson FL, Malkinson AM, Hau-gen-Strano A, et al. Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells. Oncogene 1996;13:1885-91.
    • (1996) Oncogene , vol.13 , pp. 1885-1891
    • Herzog, C.R.1    Soloff, E.V.2    McDoniels, A.L.3    Tyson, F.L.4    Malkinson, A.M.5    Hau-Gen-Strano, A.6
  • 24
    • 20944447671 scopus 로고    scopus 로고
    • Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy
    • Chaparro J, Reeds DN, Wen W, Xueping E, Klein S, Semenkovich CF, et al. Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy. Metabolism 2005;54:561-7.
    • (2005) Metabolism , vol.54 , pp. 561-567
    • Chaparro, J.1    Reeds, D.N.2    Wen, W.3    Xueping, E.4    Klein, S.5    Semenkovich, C.F.6
  • 26
    • 68149157175 scopus 로고    scopus 로고
    • Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
    • DuPage M, Dooley AL, Jacks T. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc 2009;4:1064-72.
    • (2009) Nat Protoc , vol.4 , pp. 1064-1072
    • Dupage, M.1    Dooley, A.L.2    Jacks, T.3
  • 28
    • 0034548712 scopus 로고    scopus 로고
    • K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression
    • Guerrero S, Casanova I, Farre L, Mazo A, Capella G, Mangues R. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression. Cancer Res 2000;60: 6750-6.
    • (2000) Cancer Res , vol.60 , pp. 6750-6756
    • Guerrero, S.1    Casanova, I.2    Farre, L.3    Mazo, A.4    Capella, G.5    Mangues, R.6
  • 29
    • 79960378666 scopus 로고    scopus 로고
    • Prevalence of telomerase activity in human cancer
    • Chen CH, Chen RJ. Prevalence of telomerase activity in human cancer. J Formos Med Assoc 2011;110:275-89.
    • (2011) J Formos Med Assoc , vol.110 , pp. 275-289
    • Chen, C.H.1    Chen, R.J.2
  • 30
    • 84880263616 scopus 로고    scopus 로고
    • Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4
    • Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, et al. Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4. Oncogene 2013; 32:3329-38.
    • (2013) Oncogene , vol.32 , pp. 3329-3338
    • Scherf, D.B.1    Sarkisyan, N.2    Jacobsson, H.3    Claus, R.4    Bermejo, J.L.5    Peil, B.6
  • 31
    • 77956291006 scopus 로고    scopus 로고
    • The association of telomere length and genetic variation in telomere biology genes
    • Mirabello L, Yu K, Kraft P, De Vivo I, Hunter DJ, Prescott J, et al. The association of telomere length and genetic variation in telomere biology genes. Hum Mutat 2010;31:1050-8.
    • (2010) Hum Mutat , vol.31 , pp. 1050-1058
    • Mirabello, L.1    Yu, K.2    Kraft, P.3    De Vivo, I.4    Hunter, D.J.5    Prescott, J.6
  • 33
    • 84863582866 scopus 로고    scopus 로고
    • Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumour tissue
    • Fehringer G, Liu G, Pintilie M, Sykes J, Cheng D, Liu N, et al. Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumour tissue. Cancer Epidemiol Biomarkers Prev 2012;21:1097-104.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , pp. 1097-1104
    • Fehringer, G.1    Liu, G.2    Pintilie, M.3    Sykes, J.4    Cheng, D.5    Liu, N.6
  • 35
    • 0034678411 scopus 로고    scopus 로고
    • Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells
    • Rosen K, Rak J, Leung T, Dean NM, Kerbel RS, Filmus J. Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells. J Cell Biol 2000;149: 447-56.
    • (2000) J Cell Biol , vol.149 , pp. 447-456
    • Rosen, K.1    Rak, J.2    Leung, T.3    Dean, N.M.4    Kerbel, R.S.5    Filmus, J.6
  • 36
    • 27644556527 scopus 로고    scopus 로고
    • Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance
    • Lim KH, Counter CM. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. Cancer Cell 2005;8:381-92.
    • (2005) Cancer Cell , vol.8 , pp. 381-392
    • Lim, K.H.1    Counter, C.M.2
  • 37
    • 70449109147 scopus 로고    scopus 로고
    • Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma
    • Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, et al. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 2009;462:104-7.
    • (2009) Nature , vol.462 , pp. 104-107
    • Meylan, E.1    Dooley, A.L.2    Feldser, D.M.3    Shen, L.4    Turk, E.5    Ouyang, C.6
  • 38
    • 79956355937 scopus 로고    scopus 로고
    • Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells
    • Koci L, Hyzd'alova M, Vaculova A, Hofmanova J, Kozubik A. Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells. Cytokine 2011;55:34-9.
    • (2011) Cytokine , vol.55 , pp. 34-39
    • Koci, L.1    Hyzd'Alova, M.2    Vaculova, A.3    Hofmanova, J.4    Kozubik, A.5
  • 39
    • 79954567234 scopus 로고    scopus 로고
    • Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway
    • Liu SG, Wang BS, Jiang YY, Zhang TT, Shi ZZ, Yang Y, et al. Atypical protein kinase Ciota (PKCiota) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCiota-SKP2-AKT pathway. Mol Cancer Res 2011;9:390-402.
    • (2011) Mol Cancer Res , vol.9 , pp. 390-402
    • Liu, S.G.1    Wang, B.S.2    Jiang, Y.Y.3    Zhang, T.T.4    Shi, Z.Z.5    Yang, Y.6
  • 40
    • 70350566519 scopus 로고    scopus 로고
    • Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma
    • Du XL, Yang H, Liu SG, Luo ML, Hao JJ, Zhang Y, et al. Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma. Oncogene 2009;28:3714-22.
    • (2009) Oncogene , vol.28 , pp. 3714-3722
    • Du, X.L.1    Yang, H.2    Liu, S.G.3    Luo, M.L.4    Hao, J.J.5    Zhang, Y.6
  • 41
    • 0037085271 scopus 로고    scopus 로고
    • PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy
    • Mayo LD, Dixon JE, Durden DL, Tonks NK, Donner DB. PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem 2002;277:5484-9.
    • (2002) J Biol Chem , vol.277 , pp. 5484-5489
    • Mayo, L.D.1    Dixon, J.E.2    Durden, D.L.3    Tonks, N.K.4    Donner, D.B.5
  • 42
    • 0036710512 scopus 로고    scopus 로고
    • The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network
    • Mayo LD, Donner DB. The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network. Trends Biochem Sci 2002;27:462-7.
    • (2002) Trends Biochem Sci , vol.27 , pp. 462-467
    • Mayo, L.D.1    Donner, D.B.2
  • 43
    • 84874334011 scopus 로고    scopus 로고
    • Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3-and Bim-dependent mechanism
    • Rahmani M, Aust MM, Attkisson E, Williams DC Jr, Ferreira-Gon-zalez A, Grant S. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3-and Bim-dependent mechanism. Cancer Res 2013;73:1340-51.
    • (2013) Cancer Res , vol.73 , pp. 1340-1351
    • Rahmani, M.1    Aust, M.M.2    Attkisson, E.3    Williams Jr., D.C.4    Ferreira-Gonzalez, A.5    Grant, S.6
  • 44
    • 34248994239 scopus 로고    scopus 로고
    • Bcl-XL small interfering RNA sensitizes cisplatin-resistant human lung adeno-carcinoma cells
    • Lei X, Huang Z, Zhong M, Zhu B, Tang S, Liao D. Bcl-XL small interfering RNA sensitizes cisplatin-resistant human lung adeno-carcinoma cells. Acta Biochim Biophys Sin (Shanghai) 2007;39: 344-50.
    • (2007) Acta Biochim Biophys Sin (Shanghai) , vol.39 , pp. 344-350
    • Lei, X.1    Huang, Z.2    Zhong, M.3    Zhu, B.4    Tang, S.5    Liao, D.6
  • 45
    • 69449090136 scopus 로고    scopus 로고
    • The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung
    • Zienolddiny S, Skaug V, Landvik NE, Ryberg D, Phillips DH, Houlston R, et al. The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. Carcinogenesis 2009;30:1368-71.
    • (2009) Carcinogenesis , vol.30 , pp. 1368-1371
    • Zienolddiny, S.1    Skaug, V.2    Landvik, N.E.3    Ryberg, D.4    Phillips, D.H.5    Houlston, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.