Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells

Cytokine

Volumn 55, Issue 1, 2011, Pages 34-39

  Kočí, Lenka ^a   Hýžd'alová, Martina ^a   Vaculová, Alena ^a   Hofmanová, Jiřina ^a   Kozubík, Alois ^a  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

Anoikis; Colon cancer; PI3K Akt pathway; TRAIL

Indexed keywords

FOCAL ADHESION KINASE; INTEGRIN LINKED KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANOIKIS; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CANCER SURVIVAL; CARCINOMA CELL; CELL ACTIVATION; CELL ADHESION; CELL SURFACE; COLON ADENOCARCINOMA; COLON MUCOSA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL;

ADENOCARCINOMA; ANOIKIS; CELL ADHESION; CELL MEMBRANE; COLONIC NEOPLASMS; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; EPITHELIAL CELLS; FETUS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HT29 CELLS; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 79956355937     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2011.03.013     Document Type: Article

References (35)

1. Coates J.M., Galante J.M., Bold R.J. Cancer therapy beyond apoptosis: autophagy and anoikis as mechanisms of cell death. J Surg Res 2010, 164:301-308.
2. Parsons J.T. Focal adhesion kinase: the first ten years. J Cell Sci 2003, 116:1409-1416.
3. Attwell S., Roskelley C., Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene 2000, 19:3811-3815.
4. Acconcia F., Barnes C.J., Singh R.R., Talukder A.H., Kumar R. Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase. Proc Natl Acad Sci USA 2007, 104:6782-6787.
5. Hess F., Estrugo D., Fischer A., Belka C., Cordes N. Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells. Oncogene 2007, 26:1372-1384.
6. Sheng H., Shao J., Townsend C.M., Evers B.M. Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut 2003, 52:1472-1478.
7. Schatzmann F., Marlow R., Streuli C.H. Integrin signaling and mammary cell function. J Mammary Gland Biol Neoplasia 2003, 8:395-408.
8. Shamimi-Noori S., Yeow W.S., Ziauddin M.F., Xin H., Tran T.L., Xie J., et al. Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway. Cancer Gene Ther 2008, 15:356-370.
9. Pianetti S., Arsura M., Romieu-Mourez R., Coffey R.J., Sonenshein G.E. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001, 20:1287-1299.
10. Maurer U., Charvet C., Wagman A.S., Dejardin E., Green D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell 2006, 21:749-760.
11. Park S.J., Sohn H.Y., Yoon J., Park S.I. Down-regulation of FoxO-dependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells. Cell Signal 2009, 21:1495-1503.
12. Simpson C.D., Anyiwe K., Schimmer A.D. Anoikis resistance and tumor metastasis. Cancer Lett 2008, 272:177-185.
13. Walczak H., Miller R.E., Ariail K., Gliniak B., Griffith T.S., Kubin M., et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999, 5:157-163.
14. Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000, 12:611-620.
15. Geserick P., Drewniok C., Hupe M., Haas T.L., Diessenbacher P., Sprick M.R., et al. Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis. Oncogene 2008, 27:3211-3220.
16. Vaculova A., Zhivotovsky B. Caspases: determination of their activities in apoptotic cells. Methods Enzymol 2008, 442:157-181.
17. Wang S. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 2008, 27:6207-6215.
18. Tamagiku Y., Sonoda Y., Kunisawa M., Ichikawa D., Murakami Y., Aizu-Yokota E., et al. Down-regulation of procaspase-8 expression by focal adhesion kinase protects HL-60 cells from TRAIL-induced apoptosis. Biochem Biophys Res Commun 2004, 323:445-452.
19. Lane D, Goncharenko-Khaider N, Rancourt C, Piche A. Ovarian cancer ascites protects from TRAIL-induced cell death through alphavbeta5 integrin-mediated focal adhesion kinase and Akt activation. Oncogene 2010.
20. Moscona A., Moscona H. The dissociation and aggregation of cells from organ rudiments of the early chick embryo. J Anat 1952, 86:287-301.
21. Hofmanova J., Vaculova A., Hyzd'alova M., Kozubik A. Response of normal and colon cancer epithelial cells to TNF-family apoptotic inducers. Oncol Rep 2008, 19:567-573.
22. Vaculova A., Hofmanova J., Zatloukalova J., Kozubik A. Differences in TRAIL-induced changes of Mcl-1 expression among distinct human colon epithelial cell lines. Exp Cell Res 2009, 315:3259-3266.
23. Mawji I.A., Simpson C.D., Gronda M., Williams M.A., Hurren R., Henderson C.J., et al. A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis. Cancer Res 2007, 67:8307-8315.
24. Marconi A., Atzei P., Panza C., Fila C., Tiberio R., Truzzi F., et al. FLICE/caspase-8 activation triggers anoikis induced by beta1-integrin blockade in human keratinocytes. J Cell Sci 2004, 117:5815-5823.
25. Liu G., Meng X., Jin Y., Bai J., Zhao Y., Cui X., et al. Inhibitory role of focal adhesion kinase on anoikis in the lung cancer cell A549. Cell Biol Int 2008, 32:663-670.
26. Canel M., Secades P., Rodrigo J.P., Cabanillas R., Herrero A., Suarez C., et al. Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number. Clin Cancer Res 2006, 12:3272-3279.
27. Dida F., Li Y., Iwao A., Deguchi T., Azuma E., Komada Y. Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of Akt and PTEN in acute lymphoblastic leukemia cells. Exp Hematol 2008, 36:1343-1353.
28. Boisvert-Adamo K., Longmate W., Abel E.V., Aplin A.E. Mcl-1 is required for melanoma cell resistance to anoikis. Mol Cancer Res 2009, 7:549-556.
29. Soucek K., Gajduskova P., Brazdova M., Hyzd'alova M., Koci L., Vydra D., et al. Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation. Cancer Genet Cytogenet 2010, 197:107-116.
30. Siddiqui K.M., Chopra D.P. Primary and long term epithelial cell cultures from human fetal normal colonic mucosa. In Vitro 1984, 20:859-868.
31. Laguinge L.M., Samara R.N., Wang W., El-Deiry W.S., Corner G., Augenlicht L., et al. DR5 receptor mediates anoikis in human colorectal carcinoma cell lines. Cancer Res 2008, 68:909-917.
32. Grosse-Wilde A., Voloshanenko O., Bailey S.L., Longton G.M., Schaefer U., Csernok A.I., et al. TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. J Clin Invest 2008, 118:100-110.
33. Lane D., Cartier A., Rancourt C., Piche A. Cell detachment modulates TRAIL resistance in ovarian cancer cells by downregulating the phosphatidylinositol 3-kinase/Akt pathway. Int J Gynecol Cancer 2008, 18:670-676.
34. Xiao C., Yang B.F., Song J.H., Schulman H., Li L., Hao C. Inhibition of CaMKII-mediated c-FLIP expression sensitizes malignant melanoma cells to TRAIL-induced apoptosis. Exp Cell Res 2005, 304:244-255.
35. Wang L., Lim E.J., Toborek M., Hennig B. The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation. Metabolism 2008, 57:1328-1339.