메뉴 건너뛰기




Volumn 4, Issue , 2010, Pages

Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANTIBODY SPECIFICITY; ARTICLE; BRAIN; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; HUMAN; METABOLISM; PATHOLOGY;

EID: 77957296042     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-4-136     Document Type: Article
Times cited : (81)

References (63)
  • 2
    • 0035399655 scopus 로고    scopus 로고
    • Energy Hypometabolism in Posterior Cingulate Cortex of Alzheimer's Patients: Superficial Laminar Cytochrome Oxidase Associated with Disease Duration
    • Valla J, Berndt JD, Gonzalez-Lima F. Energy Hypometabolism in Posterior Cingulate Cortex of Alzheimer's Patients: Superficial Laminar Cytochrome Oxidase Associated with Disease Duration. Journal of Neuroscience 2001, 21(13):4923-4930.
    • (2001) Journal of Neuroscience , vol.21 , Issue.13 , pp. 4923-4930
    • Valla, J.1    Berndt, J.D.2    Gonzalez-Lima, F.3
  • 3
    • 0026952546 scopus 로고
    • Reorganization of Cingulate Cortex in Alzheimer's Disease: Neuron Loss, Neuritic Plaques, and Muscarinic Receptor Binding
    • 10.1093/cercor/2.6.526, 1477528
    • Vogt BA, Crino PB, Vogt LJ. Reorganization of Cingulate Cortex in Alzheimer's Disease: Neuron Loss, Neuritic Plaques, and Muscarinic Receptor Binding. Cereb Cortex 1992, 2(6):526-535. 10.1093/cercor/2.6.526, 1477528.
    • (1992) Cereb Cortex , vol.2 , Issue.6 , pp. 526-535
    • Vogt, B.A.1    Crino, P.B.2    Vogt, L.J.3
  • 4
    • 0034087784 scopus 로고    scopus 로고
    • Region-Specific Neurotrophin Imbalances in Alzheimer Disease
    • 10.1001/archneur.57.6.846, 10867782
    • Hock C, Heese K, Hulette C, Rosenberg C, Otten U. Region-Specific Neurotrophin Imbalances in Alzheimer Disease. Archives of neurology 2000, 57(6):846-851. 10.1001/archneur.57.6.846, 10867782.
    • (2000) Archives of neurology , vol.57 , Issue.6 , pp. 846-851
    • Hock, C.1    Heese, K.2    Hulette, C.3    Rosenberg, C.4    Otten, U.5
  • 5
    • 0031596284 scopus 로고    scopus 로고
    • Evolution of neuronal changes in the course of Alzheimer's disease
    • Braak H, Braak E. Evolution of neuronal changes in the course of Alzheimer's disease. J Neural Transm Suppl 1998, 53:127-140.
    • (1998) J Neural Transm Suppl , vol.53 , pp. 127-140
    • Braak, H.1    Braak, E.2
  • 6
    • 3042514191 scopus 로고    scopus 로고
    • Coexpression Analysis of Human Genes Across Many Microarray Data Sets
    • 10.1101/gr.1910904, 419787, 15173114
    • Lee HK, Hsu AK, Sajdak J, Qin J, Pavlidis P. Coexpression Analysis of Human Genes Across Many Microarray Data Sets. Genome Research 2004, 14(6):1085-1094. 10.1101/gr.1910904, 419787, 15173114.
    • (2004) Genome Research , vol.14 , Issue.6 , pp. 1085-1094
    • Lee, H.K.1    Hsu, A.K.2    Sajdak, J.3    Qin, J.4    Pavlidis, P.5
  • 7
    • 34548550573 scopus 로고    scopus 로고
    • Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process
    • 10.1093/bioinformatics/btm309, 17553854
    • Elo LL, Jarvenpaa H, Oresic M, Lahesmaa R, Aittokallio T. Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process. Bioinformatics 2007, 23(16):2096-2103. 10.1093/bioinformatics/btm309, 17553854.
    • (2007) Bioinformatics , vol.23 , Issue.16 , pp. 2096-2103
    • Elo, L.L.1    Jarvenpaa, H.2    Oresic, M.3    Lahesmaa, R.4    Aittokallio, T.5
  • 8
    • 33845231723 scopus 로고    scopus 로고
    • Conservation and evolution of gene coexpression networks in human and chimpanzee brains
    • 10.1073/pnas.0605938103, 1693857, 17101986
    • Oldham MC, Horvath S, Geschwind DH. Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proc Natl Acad Sci USA 2006, 103(47):17973-17978. 10.1073/pnas.0605938103, 1693857, 17101986.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.47 , pp. 17973-17978
    • Oldham, M.C.1    Horvath, S.2    Geschwind, D.H.3
  • 9
    • 0141993704 scopus 로고    scopus 로고
    • A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules
    • 10.1126/science.1087447, 12934013
    • Stuart JM, Segal E, Koller D, Kim SK. A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules. Science 2003, 302(5643):249-255. 10.1126/science.1087447, 12934013.
    • (2003) Science , vol.302 , Issue.5643 , pp. 249-255
    • Stuart, J.M.1    Segal, E.2    Koller, D.3    Kim, S.K.4
  • 10
    • 33645221650 scopus 로고    scopus 로고
    • Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks
    • 10.1186/1471-2164-7-40, 1413526, 16515682
    • Carlson MR, Zhang B, Fang Z, Mischel PS, Horvath S, Nelson SF. Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC Genomics 2006, 7:40. 10.1186/1471-2164-7-40, 1413526, 16515682.
    • (2006) BMC Genomics , vol.7 , pp. 40
    • Carlson, M.R.1    Zhang, B.2    Fang, Z.3    Mischel, P.S.4    Horvath, S.5    Nelson, S.F.6
  • 11
    • 4644326931 scopus 로고    scopus 로고
    • Genomic analysis of regulatory network dynamics reveals large topological changes
    • 10.1038/nature02782, 15372033
    • Luscombe NM, Babu MM, Yu H, Snyder M, Teichmann SA, Gerstein M. Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 2004, 431:308-312. 10.1038/nature02782, 15372033.
    • (2004) Nature , vol.431 , pp. 308-312
    • Luscombe, N.M.1    Babu, M.M.2    Yu, H.3    Snyder, M.4    Teichmann, S.A.5    Gerstein, M.6
  • 12
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • 10.1007/BF00308809, 1759558
    • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica 1991, 82:239-259. 10.1007/BF00308809, 1759558.
    • (1991) Acta Neuropathologica , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 13
    • 0037172826 scopus 로고    scopus 로고
    • Phases of Abeta-deposition in the human brain and its relevance for the development of AD
    • Thal DR, Rub U, Orantes M, Braak H. Phases of Abeta-deposition in the human brain and its relevance for the development of AD. Neurology 2002, 58(12):1791-1800.
    • (2002) Neurology , vol.58 , Issue.12 , pp. 1791-1800
    • Thal, D.R.1    Rub, U.2    Orantes, M.3    Braak, H.4
  • 14
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 15
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionising radiation response
    • 10.1073/pnas.091062498, 33173, 11309499
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionising radiation response. Proc Natl Acad Sci USA 2001, 98:5116-5121. 10.1073/pnas.091062498, 33173, 11309499.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 16
    • 33645326509 scopus 로고    scopus 로고
    • Comparison of Affymetrix GeneChip expression measures
    • 10.1093/bioinformatics/btk046, 16410320
    • Irizarry RA, Wu Z, Jaffee HA. Comparison of Affymetrix GeneChip expression measures. Bioinformatics 2006, 22(7):789-794. 10.1093/bioinformatics/btk046, 16410320.
    • (2006) Bioinformatics , vol.22 , Issue.7 , pp. 789-794
    • Irizarry, R.A.1    Wu, Z.2    Jaffee, H.A.3
  • 19
    • 77649168721 scopus 로고    scopus 로고
    • A general co-expression network-based approach to gene expression analysis: comparison and applications
    • 10.1186/1752-0509-4-8, 2829495, 20122284
    • Ruan J, Dean AK, Zhang W. A general co-expression network-based approach to gene expression analysis: comparison and applications. BMC systems biology 2010, 4:8. 10.1186/1752-0509-4-8, 2829495, 20122284.
    • (2010) BMC systems biology , vol.4 , pp. 8
    • Ruan, J.1    Dean, A.K.2    Zhang, W.3
  • 20
    • 49449086368 scopus 로고    scopus 로고
    • Survival of the sparsest: robust gene networks are parsimonious
    • 10.1038/msb.2008.52, 2538912, 18682703
    • Leclerc RD. Survival of the sparsest: robust gene networks are parsimonious. Molecular systems biology 2008, 4:213. 10.1038/msb.2008.52, 2538912, 18682703.
    • (2008) Molecular systems biology , vol.4 , pp. 213
    • Leclerc, R.D.1
  • 21
    • 55049095941 scopus 로고    scopus 로고
    • Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases
    • 10.1186/gb-2008-9-10-r148, 2760875, 18842138
    • Ray M, Ruan J, Zhang W. Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases. Genome Biology 2008, 9(10):R148. 10.1186/gb-2008-9-10-r148, 2760875, 18842138.
    • (2008) Genome Biology , vol.9 , Issue.10
    • Ray, M.1    Ruan, J.2    Zhang, W.3
  • 22
    • 0037199968 scopus 로고    scopus 로고
    • Hierarchical Organization of Modularity in Metabolic Networks
    • 10.1126/science.1073374, 12202830
    • Ravasz E, Somera AL, Mongru DA, Oltvai ZN, Barabasi AL. Hierarchical Organization of Modularity in Metabolic Networks. Science 2002, 297(5586):1551-1555. 10.1126/science.1073374, 12202830.
    • (2002) Science , vol.297 , Issue.5586 , pp. 1551-1555
    • Ravasz, E.1    Somera, A.L.2    Mongru, D.A.3    Oltvai, Z.N.4    Barabasi, A.L.5
  • 23
    • 23944458138 scopus 로고    scopus 로고
    • A General Framework for Weighted Gene Co-Expression Network Analysis
    • 10.2202/1544-6115.1128, 16646834
    • Zhang B, Horvath S. A General Framework for Weighted Gene Co-Expression Network Analysis. Statistical Applications in Genetics and Molecular Biology 2005, 4(1). 10.2202/1544-6115.1128, 16646834.
    • (2005) Statistical Applications in Genetics and Molecular Biology , vol.4 , Issue.1
    • Zhang, B.1    Horvath, S.2
  • 24
    • 57649201350 scopus 로고    scopus 로고
    • FitSNPs: Highly differentially expressed genes are more likely to have variants associated with disease
    • 10.1186/gb-2008-9-12-r170, 2646274, 19061490
    • Chen R, Morgan AA, Dudley J, Deshpande T, Li L, Kodama K, Chaing AP, Butte AJ. FitSNPs: Highly differentially expressed genes are more likely to have variants associated with disease. Genome Biology 2008, 9(12):R170. 10.1186/gb-2008-9-12-r170, 2646274, 19061490.
    • (2008) Genome Biology , vol.9 , Issue.12
    • Chen, R.1    Morgan, A.A.2    Dudley, J.3    Deshpande, T.4    Li, L.5    Kodama, K.6    Chaing, A.P.7    Butte, A.J.8
  • 25
    • 0038448169 scopus 로고    scopus 로고
    • Application of disease-associated differentially expressed genes: Mining for functional candidate genes for mastitis resistance in cattle
    • 10.1186/1297-9686-35-S1-S19, 12927078
    • Schwerin M, Czernek-Schafer D, Goldammer T, Kata SR, Womack JE, Pareek R, Pareek C, Walawski K, Brunner RM. Application of disease-associated differentially expressed genes: Mining for functional candidate genes for mastitis resistance in cattle. Genet Sel Evol 2003, 35(1):S19-34. 10.1186/1297-9686-35-S1-S19, 12927078.
    • (2003) Genet Sel Evol , vol.35 , Issue.1
    • Schwerin, M.1    Czernek-Schafer, D.2    Goldammer, T.3    Kata, S.R.4    Womack, J.E.5    Pareek, R.6    Pareek, C.7    Walawski, K.8    Brunner, R.M.9
  • 26
    • 34548222087 scopus 로고    scopus 로고
    • Evidence of EGR1 as a differentially expressed gene among proliferative skin diseases
    • 10.1007/s11568-007-9010-9, 2276883, 18923931
    • Fang M, Wee SA, Ronski K, Fan H, Tao S, Lin Q. Evidence of EGR1 as a differentially expressed gene among proliferative skin diseases. Genomic Medicine 2007, 1(1-2):75-85. 10.1007/s11568-007-9010-9, 2276883, 18923931.
    • (2007) Genomic Medicine , vol.1 , Issue.1-2 , pp. 75-85
    • Fang, M.1    Wee, S.A.2    Ronski, K.3    Fan, H.4    Tao, S.5    Lin, Q.6
  • 28
    • 11144286011 scopus 로고    scopus 로고
    • Selecting differentially expressed genes for colon tumor classification
    • Fujarewicz K, Wiench M. Selecting differentially expressed genes for colon tumor classification. Int J Appl Math Comput Sci 2003, 13(3):327-335.
    • (2003) Int J Appl Math Comput Sci , vol.13 , Issue.3 , pp. 327-335
    • Fujarewicz, K.1    Wiench, M.2
  • 30
    • 4143134783 scopus 로고    scopus 로고
    • Finding predictive gene groups from microarray data
    • Dettling M, Buhlmann P. Finding predictive gene groups from microarray data. J Multivariate Anal 2004, 90:106-131.
    • (2004) J Multivariate Anal , vol.90 , pp. 106-131
    • Dettling, M.1    Buhlmann, P.2
  • 31
    • 29144488330 scopus 로고    scopus 로고
    • Robust classification modeling on microarray data using misclassification penalized posterior
    • 10.1093/bioinformatics/bti1020, 15961487
    • Soukup M, Cho H, Lee J. Robust classification modeling on microarray data using misclassification penalized posterior. Bioinformatics 2005, 21(1):i423-i430. 10.1093/bioinformatics/bti1020, 15961487.
    • (2005) Bioinformatics , vol.21 , Issue.1
    • Soukup, M.1    Cho, H.2    Lee, J.3
  • 33
    • 37549052542 scopus 로고    scopus 로고
    • Syntaxin 16 is enriched in neuronal dendrites and may have a role in neurite outgrowth
    • 10.1080/09687680701504649, 17852734
    • Chua CE, Tang BL. Syntaxin 16 is enriched in neuronal dendrites and may have a role in neurite outgrowth. Mol Membr Biol 2008, 25(1):35-45. 10.1080/09687680701504649, 17852734.
    • (2008) Mol Membr Biol , vol.25 , Issue.1 , pp. 35-45
    • Chua, C.E.1    Tang, B.L.2
  • 34
    • 34250680469 scopus 로고    scopus 로고
    • F-actin binding is essential for coronin 1B function in vivo
    • 10.1242/jcs.007641, 17456547
    • Cai L, Makhov AM, Bear JE. F-actin binding is essential for coronin 1B function in vivo. J Cell Sci 2007, 120(10):1779-1790. 10.1242/jcs.007641, 17456547.
    • (2007) J Cell Sci , vol.120 , Issue.10 , pp. 1779-1790
    • Cai, L.1    Makhov, A.M.2    Bear, J.E.3
  • 35
    • 42949090556 scopus 로고    scopus 로고
    • The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels
    • 10.1074/jbc.M709729200, 18048348
    • Odell AF, Van Helden DF, Scott JL. The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels. J Biol Chem 2008, 283(7):4395-4407. 10.1074/jbc.M709729200, 18048348.
    • (2008) J Biol Chem , vol.283 , Issue.7 , pp. 4395-4407
    • Odell, A.F.1    Van Helden, D.F.2    Scott, J.L.3
  • 36
    • 0037415614 scopus 로고    scopus 로고
    • EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
    • 10.1083/jcb.200212057, 2172667, 12566430
    • Maul RS, Song Y, Amann KJ, Gerbin SC, Pollard TD, Chang DD. EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. J Cell Biol 2003, 160(3):399-407. 10.1083/jcb.200212057, 2172667, 12566430.
    • (2003) J Cell Biol , vol.160 , Issue.3 , pp. 399-407
    • Maul, R.S.1    Song, Y.2    Amann, K.J.3    Gerbin, S.C.4    Pollard, T.D.5    Chang, D.D.6
  • 38
    • 32244433380 scopus 로고    scopus 로고
    • Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes
    • 10.1016/j.ygeno.2005.11.001, 16377127
    • Luo C, Lu X, Stubbs L, Kim J. Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes. Genomics 2006, 87(3):348-355. 10.1016/j.ygeno.2005.11.001, 16377127.
    • (2006) Genomics , vol.87 , Issue.3 , pp. 348-355
    • Luo, C.1    Lu, X.2    Stubbs, L.3    Kim, J.4
  • 39
    • 0032529295 scopus 로고    scopus 로고
    • Cloning, chromosomal localisation and promoter analysis of the human transcription factor YY1
    • 10.1093/nar/26.16.3776, 147783, 9685495
    • Yao YL, Dupont BR, Ghosh S, Fang Y, Leach RJ, Seto E. Cloning, chromosomal localisation and promoter analysis of the human transcription factor YY1. Nucleic Acids Res 1998, 26(16):3776-3783. 10.1093/nar/26.16.3776, 147783, 9685495.
    • (1998) Nucleic Acids Res , vol.26 , Issue.16 , pp. 3776-3783
    • Yao, Y.L.1    Dupont, B.R.2    Ghosh, S.3    Fang, Y.4    Leach, R.J.5    Seto, E.6
  • 42
    • 33750576993 scopus 로고    scopus 로고
    • Role of toll-like receptor signalling in A-beta uptake and clearance
    • 10.1093/brain/awl249, 2445613, 16984903
    • Tahara K, Kim HD, Jin JJ, Maxwell JA, Li L, Fukuchi K. Role of toll-like receptor signalling in A-beta uptake and clearance. Brain 2006, 129(11):3006-3019. 10.1093/brain/awl249, 2445613, 16984903.
    • (2006) Brain , vol.129 , Issue.11 , pp. 3006-3019
    • Tahara, K.1    Kim, H.D.2    Jin, J.J.3    Maxwell, J.A.4    Li, L.5    Fukuchi, K.6
  • 43
    • 45849105153 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
    • 10.1186/1742-2094-5-23, 2430555, 18510752
    • Jin JJ, Kim HD, Maxwell JA, Li L, Fukuchi K. Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation 2008, 5:23. 10.1186/1742-2094-5-23, 2430555, 18510752.
    • (2008) J Neuroinflammation , vol.5 , pp. 23
    • Jin, J.J.1    Kim, H.D.2    Maxwell, J.A.3    Li, L.4    Fukuchi, K.5
  • 44
    • 0032471541 scopus 로고    scopus 로고
    • Molecular genetics of the caveolin gene family implications for human cancers, diabetes, Alzheimer's disease, and muscular dystrophy
    • 10.1086/302172, 1377628, 9837809
    • Engelman JA, Zhang X, Galbiati F, Volonte D, Sotgia F, Pestell RG, Minetti C, Scherer PE, Okamoto T, Lisanti MP. Molecular genetics of the caveolin gene family implications for human cancers, diabetes, Alzheimer's disease, and muscular dystrophy. Am J Hum Genet 1998, 63(6):1578-1587. 10.1086/302172, 1377628, 9837809.
    • (1998) Am J Hum Genet , vol.63 , Issue.6 , pp. 1578-1587
    • Engelman, J.A.1    Zhang, X.2    Galbiati, F.3    Volonte, D.4    Sotgia, F.5    Pestell, R.G.6    Minetti, C.7    Scherer, P.E.8    Okamoto, T.9    Lisanti, M.P.10
  • 45
    • 0027490614 scopus 로고
    • Staging of Alzheimer-related cortical destruction
    • 10.1159/000116984, 8307060
    • Braak H, Braak E, Bohl J. Staging of Alzheimer-related cortical destruction. Eur Neurol 1993, 33(6):403-408. 10.1159/000116984, 8307060.
    • (1993) Eur Neurol , vol.33 , Issue.6 , pp. 403-408
    • Braak, H.1    Braak, E.2    Bohl, J.3
  • 47
    • 37849050242 scopus 로고    scopus 로고
    • Neurotrophic factors in Alzheimer's disease: role of axonal transport
    • Schindowski K, Belarbi K, Buee L. Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes, Brain and Behaviour 2008, 7(s1):43-56.
    • (2008) Genes, Brain and Behaviour , vol.7 , Issue.S1 , pp. 43-56
    • Schindowski, K.1    Belarbi, K.2    Buee, L.3
  • 48
    • 34147161245 scopus 로고    scopus 로고
    • In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease
    • 10.1016/j.neuroimage.2007.01.046, 2063432, 17369054
    • Smith KD, Kallhoff V, Zheng H, Pautler RG. In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease. Neuroimage 2007, 35(4):1401-1408. 10.1016/j.neuroimage.2007.01.046, 2063432, 17369054.
    • (2007) Neuroimage , vol.35 , Issue.4 , pp. 1401-1408
    • Smith, K.D.1    Kallhoff, V.2    Zheng, H.3    Pautler, R.G.4
  • 49
    • 0034302872 scopus 로고    scopus 로고
    • Neuroinflammatory signaling upregulation in Alzheimer's disease
    • 10.1023/A:1007627725251, 11059791
    • Lukiw WJ, Bazan NG. Neuroinflammatory signaling upregulation in Alzheimer's disease. Neurochem Res 2000, 25(9-10):1173-1184. 10.1023/A:1007627725251, 11059791.
    • (2000) Neurochem Res , vol.25 , Issue.9-10 , pp. 1173-1184
    • Lukiw, W.J.1    Bazan, N.G.2
  • 50
    • 34249870149 scopus 로고    scopus 로고
    • A beneficial role for IL-1beta in Alzheimer disease?
    • 10.1172/JCI32356, 1878536, 17549252
    • Lemere CA. A beneficial role for IL-1beta in Alzheimer disease?. Journal of Clinical Investigation 2007, 117(6):1483-1485. 10.1172/JCI32356, 1878536, 17549252.
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.6 , pp. 1483-1485
    • Lemere, C.A.1
  • 52
    • 34247882772 scopus 로고    scopus 로고
    • Activation of caspase-6 in aging and mild cognitive impairment
    • 10.2353/ajpath.2007.060974, 1829454, 17392160
    • Albrecht S, Bourdeau M, Bennett D, Mufson E, Bhattacharjee M, LeBlanc AC. Activation of caspase-6 in aging and mild cognitive impairment. Am J Pathol 2007, 170(4):1200-1209. 10.2353/ajpath.2007.060974, 1829454, 17392160.
    • (2007) Am J Pathol , vol.170 , Issue.4 , pp. 1200-1209
    • Albrecht, S.1    Bourdeau, M.2    Bennett, D.3    Mufson, E.4    Bhattacharjee, M.5    LeBlanc, A.C.6
  • 53
    • 3242811902 scopus 로고    scopus 로고
    • Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease
    • 1618555, 15277226
    • Guo H, Albrecht S, Bourdeau M, Petzke T, Bergeron C, LeBlanc AC. Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease. Am J Pathol 2004, 165(2):523-531. 1618555, 15277226.
    • (2004) Am J Pathol , vol.165 , Issue.2 , pp. 523-531
    • Guo, H.1    Albrecht, S.2    Bourdeau, M.3    Petzke, T.4    Bergeron, C.5    LeBlanc, A.C.6
  • 54
    • 4243962944 scopus 로고    scopus 로고
    • The IAP Proteins: Caspase Inhibitors and Beyond
    • Richter B, Duckett CS. The IAP Proteins: Caspase Inhibitors and Beyond. Science signalling 2000, 44:PE1.
    • (2000) Science signalling , vol.44
    • Richter, B.1    Duckett, C.S.2
  • 56
    • 0034662929 scopus 로고    scopus 로고
    • BACE2, a beta-secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein
    • 10.1073/pnas.160115697, 16930, 10931940
    • Farzan M, Schnitzler C, Vasilieva N, Leung D, Choe H. BACE2, a beta-secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein. Proc Natl Acad Sci USA 2000, 97(17):9712-9717. 10.1073/pnas.160115697, 16930, 10931940.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.17 , pp. 9712-9717
    • Farzan, M.1    Schnitzler, C.2    Vasilieva, N.3    Leung, D.4    Choe, H.5
  • 57
    • 51849150799 scopus 로고    scopus 로고
    • Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease
    • 10.1111/j.1471-4159.2008.05603.x, 2716044, 18680556
    • Chen L, Na R, Gu M, Richardson A, Ran Q. Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease. J Neurochem 2008, 107(1):197-207. 10.1111/j.1471-4159.2008.05603.x, 2716044, 18680556.
    • (2008) J Neurochem , vol.107 , Issue.1 , pp. 197-207
    • Chen, L.1    Na, R.2    Gu, M.3    Richardson, A.4    Ran, Q.5
  • 58
    • 34250864717 scopus 로고    scopus 로고
    • Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain
    • 10.1016/j.febslet.2006.10.076, 17113083
    • Stockley JH, Ravid R, O'Neill C. Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain. FEBS Letters 2006, 580(28-29):6550-6560. 10.1016/j.febslet.2006.10.076, 17113083.
    • (2006) FEBS Letters , vol.580 , Issue.28-29 , pp. 6550-6560
    • Stockley, J.H.1    Ravid, R.2    O'Neill, C.3
  • 61
    • 38449120482 scopus 로고    scopus 로고
    • Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664
    • 10.1111/j.1471-4159.2007.05031.x, 2553705, 17986220
    • Nguyen TV, Galvan V, Huang W, Banwait S, Tang H, Zhang J, Bredesen DE. Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664. J Neurochem 2008, 104(4):1065-1080. 10.1111/j.1471-4159.2007.05031.x, 2553705, 17986220.
    • (2008) J Neurochem , vol.104 , Issue.4 , pp. 1065-1080
    • Nguyen, T.V.1    Galvan, V.2    Huang, W.3    Banwait, S.4    Tang, H.5    Zhang, J.6    Bredesen, D.E.7
  • 63
    • 39649103409 scopus 로고    scopus 로고
    • Modular and laminar pathology of Brodmann's area 37 in Alzheimer's disease
    • Thangavel R, Sahu SK, Van Hoesen GW, Zaheer A. Modular and laminar pathology of Brodmann's area 37 in Alzheimer's disease. Neuroanatomy 2008, 152(1):50-55.
    • (2008) Neuroanatomy , vol.152 , Issue.1 , pp. 50-55
    • Thangavel, R.1    Sahu, S.K.2    Van Hoesen, G.W.3    Zaheer, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.