-
1
-
-
0036324006
-
Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts
-
Akiyama-Uchida Y, Ashizawa N, Ohtsuru A, Seto S, Tsukazaki T, Kikuchi H, Yamashita S, Yano K. Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts. Hypertension 40: 148-154, 2002.
-
(2002)
Hypertension
, vol.40
, pp. 148-154
-
-
Akiyama-Uchida, Y.1
Ashizawa, N.2
Ohtsuru, A.3
Seto, S.4
Tsukazaki, T.5
Kikuchi, H.6
Yamashita, S.7
Yano, K.8
-
2
-
-
0037306226
-
Significance of matrix metalloproteinases in norepinephrine-induced remodelling of rat hearts
-
Briest W, Holzl A, Rassler B, Deten A, Baba HA, Zimmer HG. Significance of matrix metalloproteinases in norepinephrine-induced remodelling of rat hearts. Cardiovasc Res 57: 379-387, 2003.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 379-387
-
-
Briest, W.1
Holzl, A.2
Rassler, B.3
Deten, A.4
Baba, H.A.5
Zimmer, H.G.6
-
3
-
-
13844312743
-
The cardiac fibroblast: Therapeutic target in myocardial remodeling and failure
-
Brown RD, Ambler SK, Mitchell MD, Long CS. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45: 657-687, 2005.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 657-687
-
-
Brown, R.D.1
Ambler, S.K.2
Mitchell, M.D.3
Long, C.S.4
-
4
-
-
2642580639
-
Doxycycline ameliorates ischemic and border-zone remodeling and endothelial dysfunction after myocardial infarction in rats
-
Camp TM, Tyagi SC, Aru GM, Hayden MR, Mehta JL. Doxycycline ameliorates ischemic and border-zone remodeling and endothelial dysfunction after myocardial infarction in rats. J Heart Lung Transplant 23: 729-736, 2004.
-
(2004)
J Heart Lung Transplant
, vol.23
, pp. 729-736
-
-
Camp, T.M.1
Tyagi, S.C.2
Aru, G.M.3
Hayden, M.R.4
Mehta, J.L.5
-
5
-
-
80053644783
-
Epinephrine-induced MMP expression is different between skeletal fibroblasts and myoblasts
-
Cha MC, Purslow PP. Epinephrine-induced MMP expression is different between skeletal fibroblasts and myoblasts. Cell Biochem Funct 29: 603-609, 2011.
-
(2011)
Cell Biochem Funct
, vol.29
, pp. 603-609
-
-
Cha, M.C.1
Purslow, P.P.2
-
6
-
-
0142212329
-
Regulation of matrix metalloproteinases: An overview
-
Chakraborti S, Mandal M, Das S, Mandal A, Chakraborti T. Regulation of matrix metalloproteinases: an overview. Mol Cell Biochem 253: 269-285, 2003.
-
(2003)
Mol Cell Biochem
, vol.253
, pp. 269-285
-
-
Chakraborti, S.1
Mandal, M.2
Das, S.3
Mandal, A.4
Chakraborti, T.5
-
7
-
-
37349022878
-
Targeting focal adhesion kinase with small interfering RNA prevents and reverses load-induced cardiac hypertrophy in mice
-
Clemente CF, Tornatore TF, Theizen TH, Deckmann AC, Pereira TC, Lopes-Cendes I, Souza JR, Franchini KG. Targeting focal adhesion kinase with small interfering RNA prevents and reverses load-induced cardiac hypertrophy in mice. Circ Res 101: 1339-1348, 2007.
-
(2007)
Circ Res
, vol.101
, pp. 1339-1348
-
-
Clemente, C.F.1
Tornatore, T.F.2
Theizen, T.H.3
Deckmann, A.C.4
Pereira, T.C.5
Lopes-Cendes, I.6
Souza, J.R.7
Franchini, K.G.8
-
8
-
-
0034887852
-
Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation
-
Coker ML, Jolly JR, Joffs C, Etoh T, Holder JR, Bond BR, Spinale FG. Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation. Am J Physiol Heart Circ Physiol 281: H543-H551, 2001.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.281
-
-
Coker, M.L.1
Jolly, J.R.2
Joffs, C.3
Etoh, T.4
Holder, J.R.5
Bond, B.R.6
Spinale, F.G.7
-
9
-
-
77952398280
-
FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex
-
Dalla Costa AP, Clemente CF, Carvalho HF, Carvalheira JB, Nadruz W Jr, Franchini KG. FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex. Cardiovasc Res 86: 421-431, 2010.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 421-431
-
-
Dalla Costa, A.P.1
Clemente, C.F.2
Carvalho, H.F.3
Carvalheira, J.B.4
Nadruz Jr., W.5
Franchini, K.G.6
-
10
-
-
0033932709
-
Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
-
Ducharme A, Frantz S, Aikawa M, Rabkin E, Lindsey M, Rohde LE, Schoen FJ, Kelly RA, Werb Z, Libby P, Lee RT. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest 106: 55-62, 2000.
-
(2000)
J Clin Invest
, vol.106
, pp. 55-62
-
-
Ducharme, A.1
Frantz, S.2
Aikawa, M.3
Rabkin, E.4
Lindsey, M.5
Rohde, L.E.6
Schoen, F.J.7
Kelly, R.A.8
Werb, Z.9
Libby, P.10
Lee, R.T.11
-
11
-
-
67650531390
-
Sympathetic nervous system activation in human heart failure: Clinical implications of an updated model
-
Floras JS. Sympathetic nervous system activation in human heart failure: clinical implications of an updated model. J Am Coll Cardiol 54: 375-385, 2009.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 375-385
-
-
Floras, J.S.1
-
13
-
-
0027945391
-
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats
-
Golomb E, Abassi ZA, Cuda G, Stylianou M, Panchal VR, Trachewsky D, Keiser HR. Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats. Am J Physiol Heart Circ Physiol 267: H1496-H1506, 1994.
-
(1994)
Am J Physiol Heart Circ Physiol
, vol.267
-
-
Golomb, E.1
Abassi, Z.A.2
Cuda, G.3
Stylianou, M.4
Panchal, V.R.5
Trachewsky, D.6
Keiser, H.R.7
-
14
-
-
33845666103
-
FAK-dependent regulation of myofibroblast differentiation
-
Greenberg RS, Bernstein AM, Benezra M, Gelman IH, Taliana L, Masur SK. FAK-dependent regulation of myofibroblast differentiation. FASEB J 20: 1006-1008, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 1006-1008
-
-
Greenberg, R.S.1
Bernstein, A.M.2
Benezra, M.3
Gelman, I.H.4
Taliana, L.5
Masur, S.K.6
-
15
-
-
0035955728
-
MMP inhibitors augment fibroblast adhesion through stabilization of focal adhesion contacts and up-regulation of cadherin function
-
Ho AT, Voura EB, Soloway PD, Watson KL, Khokha R. MMP inhibitors augment fibroblast adhesion through stabilization of focal adhesion contacts and up-regulation of cadherin function. J Biol Chem 276: 40215-40224, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 40215-40224
-
-
Ho, A.T.1
Voura, E.B.2
Soloway, P.D.3
Watson, K.L.4
Khokha, R.5
-
16
-
-
70349973582
-
Doxycycline attenuates isoproterenol-induced myocardial fibrosis and matrix metalloproteinase activity in rats
-
Hori Y, Kunihiro S, Sato S, Yoshioka K, Hara Y, Kanai K, Hoshi F, Itoh N, Higuchi S. Doxycycline attenuates isoproterenol-induced myocardial fibrosis and matrix metalloproteinase activity in rats. Biol Pharm Bull 32: 1678-1682, 2009.
-
(2009)
Biol Pharm Bull
, vol.32
, pp. 1678-1682
-
-
Hori, Y.1
Kunihiro, S.2
Sato, S.3
Yoshioka, K.4
Hara, Y.5
Kanai, K.6
Hoshi, F.7
Itoh, N.8
Higuchi, S.9
-
17
-
-
0037200025
-
Beta-adrenergic receptormediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases
-
Kim J, Eckhart AD, Eguchi S, Koch WJ. Beta-adrenergic receptormediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases. J Biol Chem 277: 32116-32123, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 32116-32123
-
-
Kim, J.1
Eckhart, A.D.2
Eguchi, S.3
Koch, W.J.4
-
18
-
-
77955029941
-
Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor
-
Koshikawa N, Mizushima H, Minegishi T, Iwamoto R, Mekada E, Seiki M. Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor. Cancer Res 70: 6093-6103, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 6093-6103
-
-
Koshikawa, N.1
Mizushima, H.2
Minegishi, T.3
Iwamoto, R.4
Mekada, E.5
Seiki, M.6
-
19
-
-
69249218995
-
Suppression of collagen production in norepinephrine stimulated cardiac fibroblasts culture: Differential effect of alpha and beta-adrenoreceptor antagonism
-
Lai KB, Sanderson JE, Yu CM. Suppression of collagen production in norepinephrine stimulated cardiac fibroblasts culture: differential effect of alpha and beta-adrenoreceptor antagonism. Cardiovasc Drugs Ther 23: 271-280, 2009.
-
(2009)
Cardiovasc Drugs Ther
, vol.23
, pp. 271-280
-
-
Lai, K.B.1
Sanderson, J.E.2
Yu, C.M.3
-
20
-
-
80054723114
-
Effect of efonidipine on TGF-beta1-induced cardiac fibrosis through Smad2-dependent pathway in rat cardiac fibroblasts
-
Lei B, Hitomi H, Mori T, Nagai Y, Deguchi K, Mori H, Masaki T, Nakano D, Kobori H, Kitaura Y, Nishiyama A. Effect of efonidipine on TGF-beta1-induced cardiac fibrosis through Smad2-dependent pathway in rat cardiac fibroblasts. J Pharm Sci 117: 98-105, 2011.
-
(2011)
J Pharm Sci
, vol.117
, pp. 98-105
-
-
Lei, B.1
Hitomi, H.2
Mori, T.3
Nagai, Y.4
Deguchi, K.5
Mori, H.6
Masaki, T.7
Nakano, D.8
Kobori, H.9
Kitaura, Y.10
Nishiyama, A.11
-
21
-
-
0034115630
-
MMP/TIMP expression in spontaneously hypertensive heart failure rats: The effect of ACE-and MMP-inhibition
-
Li H, Simon H, Bocan TM, Peterson JT. MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE-and MMP-inhibition. Cardiovasc Res 46: 298-306, 2000.
-
(2000)
Cardiovasc Res
, vol.46
, pp. 298-306
-
-
Li, H.1
Simon, H.2
Bocan, T.M.3
Peterson, J.T.4
-
22
-
-
0001751017
-
Differential expression of tissue inhibitors of metalloproteinases in the failing human heart
-
Li YY, Feldman AM, Sun Y, McTiernan CF. Differential expression of tissue inhibitors of metalloproteinases in the failing human heart. Circulation 98: 1728-1734, 1998.
-
(1998)
Circulation
, vol.98
, pp. 1728-1734
-
-
Li, Y.Y.1
Feldman, A.M.2
Sun, Y.3
McTiernan, C.F.4
-
23
-
-
4644330057
-
p38 alpha mitogen-activated protein kinase inhibition improves cardiac function and reduces myocardial damage in isoproterenol-induced acute myocardial injury in rats
-
Li Z, Tran TT, Ma JY, O'Young G, Kapoun AM, Chakravarty S, Dugar S, Schreiner G, Protter AA. p38 alpha mitogen-activated protein kinase inhibition improves cardiac function and reduces myocardial damage in isoproterenol-induced acute myocardial injury in rats. J Cardiovasc Pharmacol 44: 486-492, 2004.
-
(2004)
J Cardiovasc Pharmacol
, vol.44
, pp. 486-492
-
-
Li, Z.1
Tran, T.T.2
Ma, J.Y.3
O'Young, G.4
Kapoun, A.M.5
Chakravarty, S.6
Dugar, S.7
Schreiner, G.8
Protter, A.A.9
-
24
-
-
34347382590
-
Cardiac sympathetic nerve terminal function in congestive heart failure
-
Liang CS. Cardiac sympathetic nerve terminal function in congestive heart failure. Acta Pharmacol Sin 28: 921-927, 2007.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 921-927
-
-
Liang, C.S.1
-
25
-
-
0141727726
-
Myocardial collagen turnover in hypertrophic cardiomyopathy
-
Lombardi R, Betocchi S, Losi MA, Tocchetti CG, Aversa M, Miranda M, D'Alessandro G, Cacace A, Ciampi Q, Chiariello M. Myocardial collagen turnover in hypertrophic cardiomyopathy. Circulation 108: 1455-1460, 2003.
-
(2003)
Circulation
, vol.108
, pp. 1455-1460
-
-
Lombardi, R.1
Betocchi, S.2
Losi, M.A.3
Tocchetti, C.G.4
Aversa, M.5
Miranda, M.6
D'Alessandro, G.7
Cacace, A.8
Ciampi, Q.9
Chiariello, M.10
-
26
-
-
4644306893
-
Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome
-
Meiners S, Hocher B, Weller A, Laule M, Stangl V, Guenther C, Godes M, Mrozikiewicz A, Baumann G, Stangl K. Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome. Hypertension 44: 471-477, 2004.
-
(2004)
Hypertension
, vol.44
, pp. 471-477
-
-
Meiners, S.1
Hocher, B.2
Weller, A.3
Laule, M.4
Stangl, V.5
Guenther, C.6
Godes, M.7
Mrozikiewicz, A.8
Baumann, G.9
Stangl, K.10
-
27
-
-
33644827365
-
beta-Adrenergic receptor-stimulated apoptosis in adult cardiac myocytes involves MMP-2-mediated disruption of beta1 integrin signaling and mitochondrial pathway
-
Menon B, Singh M, Ross RS, Johnson JN, Singh K. beta-Adrenergic receptor-stimulated apoptosis in adult cardiac myocytes involves MMP-2-mediated disruption of beta1 integrin signaling and mitochondrial pathway. Am J Physiol Cell Physiol 290: C254-C261, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Menon, B.1
Singh, M.2
Ross, R.S.3
Johnson, J.N.4
Singh, K.5
-
28
-
-
21144455107
-
Matrix metalloproteinases mediate betaadrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes
-
Menon B, Singh M, Singh K. Matrix metalloproteinases mediate betaadrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes. Am J Physiol Cell Physiol 289: C168-C176, 2005.
-
(2005)
Am J Physiol Cell Physiol
, vol.289
-
-
Menon, B.1
Singh, M.2
Singh, K.3
-
30
-
-
25444503555
-
Chronic beta-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin
-
Oliveira EM, Krieger JE. Chronic beta-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin. Eur J Pharmacol 520: 135-141, 2005.
-
(2005)
Eur J Pharmacol
, vol.520
, pp. 135-141
-
-
Oliveira, E.M.1
Krieger, J.E.2
-
31
-
-
77951205577
-
The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol
-
Peng HJ, Dai DZ, Ji H, Dai Y. The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol. Eur J Pharmacol 634: 101-106, 2010.
-
(2010)
Eur J Pharmacol
, vol.634
, pp. 101-106
-
-
Peng, H.J.1
Dai, D.Z.2
Ji, H.3
Dai, Y.4
-
32
-
-
5644304359
-
Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression
-
Polyakova V, Hein S, Kostin S, Ziegelhoeffer T, Schaper J. Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression. J Am Coll Cardiol 44: 1609-1618, 2004.
-
(2004)
J Am Coll Cardiol
, vol.44
, pp. 1609-1618
-
-
Polyakova, V.1
Hein, S.2
Kostin, S.3
Ziegelhoeffer, T.4
Schaper, J.5
-
33
-
-
2442457887
-
Activation of matrix metalloproteinases precedes left ventricular remodeling in hypertensive heart failure rats: Its inhibition as a primary effect of angiotensin-converting enzyme inhibitor
-
Sakata Y, Yamamoto K, Mano T, Nishikawa N, Yoshida J, Hori M, Miwa T, Masuyama T. Activation of matrix metalloproteinases precedes left ventricular remodeling in hypertensive heart failure rats: its inhibition as a primary effect of angiotensin-converting enzyme inhibitor. Circulation 109: 2143-2149, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2143-2149
-
-
Sakata, Y.1
Yamamoto, K.2
Mano, T.3
Nishikawa, N.4
Yoshida, J.5
Hori, M.6
Miwa, T.7
Masuyama, T.8
-
34
-
-
0037155784
-
Matrix metalloproteinases: Regulation and dysregulation in the failing heart
-
Spinale FG. Matrix metalloproteinases: regulation and dysregulation in the failing heart. Circ Res 90: 520-530, 2002.
-
(2002)
Circ Res
, vol.90
, pp. 520-530
-
-
Spinale, F.G.1
-
35
-
-
35748974863
-
Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function
-
Spinale FG. Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol Rev 87: 1285-1342, 2007.
-
(2007)
Physiol Rev
, vol.87
, pp. 1285-1342
-
-
Spinale, F.G.1
-
36
-
-
0032485851
-
Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy
-
Thomas CV, Coker ML, Zellner JL, Handy JR, Crumbley AJ, 3rd, Spinale FG. Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy. Circulation 97: 1708-1715, 1998.
-
(1998)
Circulation
, vol.97
, pp. 1708-1715
-
-
Thomas, C.V.1
Coker, M.L.2
Zellner, J.L.3
Handy, J.R.4
Crumbley III, A.J.5
Spinale, F.G.6
-
37
-
-
0042266791
-
Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes
-
Torsoni AS, Constancio SS, Nadruz W Jr, Hanks SK, Franchini KG. Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Circ Res 93: 140-147, 2003.
-
(2003)
Circ Res
, vol.93
, pp. 140-147
-
-
Torsoni, A.S.1
Constancio, S.S.2
Nadruz Jr., W.3
Hanks, S.K.4
Franchini, K.G.5
-
39
-
-
0024234870
-
Compensatory changes of sympathetic tone, the reninangiotensin-aldosterone system, vasopressin, and ANF as potential therapeutic targets in congestive heart failure
-
van Zwieten PA. Compensatory changes of sympathetic tone, the reninangiotensin-aldosterone system, vasopressin, and ANF as potential therapeutic targets in congestive heart failure. Z Kardiol 77: 67-76, 1988.
-
(1988)
Z Kardiol
, vol.77
, pp. 67-76
-
-
van Zwieten, P.A.1
-
40
-
-
3543023861
-
Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway
-
Xia H, Nho RS, Kahm J, Kleidon J, Henke CA. Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway. J Biol Chem 279: 33024-33034, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 33024-33034
-
-
Xia, H.1
Nho, R.S.2
Kahm, J.3
Kleidon, J.4
Henke, C.A.5
-
41
-
-
41149086135
-
Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells
-
Zhuang S, Kinsey GR, Rasbach K, Schnellmann RG. Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells. Am J Physiol Renal Physiol 294: F459-F468, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Zhuang, S.1
Kinsey, G.R.2
Rasbach, K.3
Schnellmann, R.G.4
|