Anti-fibrotic cardio protective efficacy of aminoguanidine against streptozotocin induced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts

Chemico-Biological Interactions

Volumn 197, Issue 2-3, 2012, Pages 119-128

  Vadla, Gangadhara Prasadachari ^a   Vellaichamy, Elangovan ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Aminoguanidine; Cardiac fibroblasts; Cardiac fibrosis; Collagen; Matrix metalloproteinases; Streptozotocin

Indexed keywords

AMINOGUANIDINE; COLLAGEN; COLLAGEN TYPE 3; CREATINE KINASE MB; GELATINASE A; GELATINASE B; GLUCOSE; HEMOGLOBIN A1C; LACTATE DEHYDROGENASE; STREPTOZOCIN; TROPONIN I;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG ACTIVITY; ENZYME ACTIVITY; FIBROBLAST; GLUCOSE BLOOD LEVEL; HEART CONTRACTION; HEART MUSCLE FIBROSIS; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; STREPTOZOCIN DIABETES; UPREGULATION;

ANIMALS; CARDIOTONIC AGENTS; COLLAGEN; DIABETES MELLITUS, EXPERIMENTAL; FIBROSIS; GENE EXPRESSION REGULATION; GLUCOSE; GUANIDINES; HEART; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MODELS, MOLECULAR; MYOCARDIUM; STREPTOZOCIN; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASES; UP-REGULATION;

MUS;

EID: 84860688150     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.04.005     Document Type: Article

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