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Volumn 23, Issue 5, 2014, Pages 1134-1150

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANIMALS, NEWBORN; ARRHYTHMIAS, CARDIAC; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; CATECHOLAMINES; CONNEXIN 43; CONNEXINS; DESMOPLAKINS; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; GENE EXPRESSION; HEART; HEART CONDUCTION SYSTEM; MAGNETIC RESONANCE IMAGING; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PHYSICAL CONDITIONING, ANIMAL;

EID: 84894083453     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt508     Document Type: Article
Times cited : (80)

References (71)
  • 1
  • 2
    • 0034679297 scopus 로고    scopus 로고
    • Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease)
    • McKoy, G., Protonotarios, N., Crosby, A., Tsatsopoulou, A., Anastasakis, A., Coonar, A., Norman, M., Baboonian, C., Jeffery, S. and McKenna, W.J. (2000) Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease). Lancet, 355, 2119-2124.
    • (2000) Lancet , vol.355 , pp. 2119-2124
    • McKoy, G.1    Protonotarios, N.2    Crosby, A.3    Tsatsopoulou, A.4    Anastasakis, A.5    Coonar, A.6    Norman, M.7    Baboonian, C.8    Jeffery, S.9    McKenna, W.J.10
  • 6
    • 33751073197 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2
    • Syrris, P., Ward, D., Evans, A., Asimaki, A., Gandjbakhch, E., Sen-Chowdhry, S. and McKenna, W.J. (2006) Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2. Am. J. Hum. Genet., 79, 978-984.
    • (2006) Am. J. Hum. Genet. , vol.79 , pp. 978-984
    • Syrris, P.1    Ward, D.2    Evans, A.3    Asimaki, A.4    Gandjbakhch, E.5    Sen-Chowdhry, S.6    McKenna, W.J.7
  • 7
    • 33745848407 scopus 로고    scopus 로고
    • Suppression of canonical Wnt/ beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
    • Garcia-Gras, E., Lombardi, R., Giocondo, M.J., Willerson, J.T., Schneider, M.D., Khoury, D.S. and Marian, A.J. (2006) Suppression of canonical Wnt/ beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J. Clin. Invest., 116, 2012-2021.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2012-2021
    • Garcia-Gras, E.1    Lombardi, R.2    Giocondo, M.J.3    Willerson, J.T.4    Schneider, M.D.5    Khoury, D.S.6    Marian, A.J.7
  • 8
    • 79952268278 scopus 로고    scopus 로고
    • Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {}b-catenin signaling
    • Li, J., Swope, D., Raess, N., Cheng, L., Muller, E.J. and Radice, G.L. (2011) Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {}b-catenin signaling. Mol. Cell. Biol., 31, 1134-1144.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 1134-1144
    • Li, J.1    Swope, D.2    Raess, N.3    Cheng, L.4    Muller, E.J.5    Radice, G.L.6
  • 12
  • 14
    • 79958142900 scopus 로고    scopus 로고
    • Novel homozygous mutation in DSP causing skin fragility-woolly hair syndrome: report of a large family and review of the desmoplakin-related phenotypes
    • Al-Owain, M., Wakil, S., Shareef, F., Al-Fatani, A., Hamadah, E., Haider, M., Al-Hindi, H., Awaji, A., Khalifa, O., Baz, B. et al. (2011) Novel homozygous mutation in DSP causing skin fragility-woolly hair syndrome: report of a large family and review of the desmoplakin-related phenotypes. Clin. Genet., 80, 50-58.
    • (2011) Clin. Genet. , vol.80 , pp. 50-58
    • Al-Owain, M.1    Wakil, S.2    Shareef, F.3    Al-Fatani, A.4    Hamadah, E.5    Haider, M.6    Al-Hindi, H.7    Awaji, A.8    Khalifa, O.9    Baz, B.10
  • 16
    • 0037811950 scopus 로고    scopus 로고
    • A recessive mutation in desmoplakin causes arrhythmogenic right ventricular dysplasia, skin disorder, and woolly hair
    • Alcalai, R., Metzger, S., Rosenheck, S., Meiner, V. and Chajek-Shaul, T. (2003) A recessive mutation in desmoplakin causes arrhythmogenic right ventricular dysplasia, skin disorder, and woolly hair. J. Am. Coll. Cardiol., 42, 319-327.
    • (2003) J. Am. Coll. Cardiol. , vol.42 , pp. 319-327
    • Alcalai, R.1    Metzger, S.2    Rosenheck, S.3    Meiner, V.4    Chajek-Shaul, T.5
  • 17
    • 0035066688 scopus 로고    scopus 로고
    • Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature
    • Gallicano, G.I., Bauer, C. and Fuchs, E. (2001) Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature. Development, 128, 929-941.
    • (2001) Development , vol.128 , pp. 929-941
    • Gallicano, G.I.1    Bauer, C.2    Fuchs, E.3
  • 18
    • 33750539318 scopus 로고    scopus 로고
    • Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice
    • Kirchhof, P., Fabritz, L., Zwiener, M., Witt, H., Schafers, M., Zellerhoff, S., Paul, M., Athai, T., Hiller, K.H., Baba, H.A. et al. (2006) Age- and training-dependent development of arrhythmogenic right ventricular cardiomyopathy in heterozygous plakoglobin-deficient mice. Circulation, 114, 1799-1806.
    • (2006) Circulation , vol.114 , pp. 1799-1806
    • Kirchhof, P.1    Fabritz, L.2    Zwiener, M.3    Witt, H.4    Schafers, M.5    Zellerhoff, S.6    Paul, M.7    Athai, T.8    Hiller, K.H.9    Baba, H.A.10
  • 19
    • 84862760898 scopus 로고    scopus 로고
    • Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study
    • Gomes, J., Finlay, M., Ahmed, A.K., Ciaccio, E.J., Asimaki, A., Saffitz, J.E., Quarta, G., Nobles, M., Syrris, P., Chaubey, S. et al. (2012) Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study. Eur. Heart J., 33, 1942-1953.
    • (2012) Eur. Heart J. , vol.33 , pp. 1942-1953
    • Gomes, J.1    Finlay, M.2    Ahmed, A.K.3    Ciaccio, E.J.4    Asimaki, A.5    Saffitz, J.E.6    Quarta, G.7    Nobles, M.8    Syrris, P.9    Chaubey, S.10
  • 20
    • 34247280500 scopus 로고    scopus 로고
    • Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression
    • Sen-Chowdhry, S., Syrris, P., Ward, D., Asimaki, A., Sevdalis, E. and McKenna, W.J. (2007) Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression. Circulation, 115, 1710-1720.
    • (2007) Circulation , vol.115 , pp. 1710-1720
    • Sen-Chowdhry, S.1    Syrris, P.2    Ward, D.3    Asimaki, A.4    Sevdalis, E.5    McKenna, W.J.6
  • 22
    • 33645757523 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy/dysplasia: clinical impact of molecular genetic studies
    • Corrado, D. and Thiene, G. (2006) Arrhythmogenic right ventricular cardiomyopathy/dysplasia: clinical impact of molecular genetic studies. Circulation, 113, 1634-1637.
    • (2006) Circulation , vol.113 , pp. 1634-1637
    • Corrado, D.1    Thiene, G.2
  • 25
    • 84856102438 scopus 로고    scopus 로고
    • Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy
    • Lombardi, R., da Graca Cabreira-Hansen, M., Bell, A., Fromm, R.R., Willerson, J.T. and Marian, A.J. (2011) Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ. Res., 109, 1342-1353.
    • (2011) Circ. Res. , vol.109 , pp. 1342-1353
    • Lombardi, R.1    da Graca Cabreira-Hansen, M.2    Bell, A.3    Fromm, R.R.4    Willerson, J.T.5    Marian, A.J.6
  • 26
    • 66149101609 scopus 로고    scopus 로고
    • Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy
    • Lombardi, R., Dong, J., Rodriguez, G., Bell, A., Leung, T.K., Schwartz, R.J., Willerson, J.T., Brugada, R. and Marian, A.J. (2009) Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ. Res., 104, 1076-1084.
    • (2009) Circ. Res. , vol.104 , pp. 1076-1084
    • Lombardi, R.1    Dong, J.2    Rodriguez, G.3    Bell, A.4    Leung, T.K.5    Schwartz, R.J.6    Willerson, J.T.7    Brugada, R.8    Marian, A.J.9
  • 27
    • 13844250348 scopus 로고    scopus 로고
    • Adipositas cordis, fatty infiltration of the right ventricle, and arrhythmogenic right ventricular cardiomyopathy. Just a matter of fat?
    • Basso, C. and Thiene, G. (2005) Adipositas cordis, fatty infiltration of the right ventricle, and arrhythmogenic right ventricular cardiomyopathy. Just a matter of fat? Cardiovasc. Pathol., 14, 37-41.
    • (2005) Cardiovasc. Pathol. , vol.14 , pp. 37-41
    • Basso, C.1    Thiene, G.2
  • 31
    • 33748486911 scopus 로고    scopus 로고
    • alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture
    • Sheikh, F., Chen, Y., Liang, X., Hirschy, A., Stenbit, A.E., Gu, Y., Dalton, N.D., Yajima, T., Lu, Y., Knowlton, K.U. et al. (2006) alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation, 114, 1046- 1055.
    • (2006) Circulation , vol.114
    • Sheikh, F.1    Chen, Y.2    Liang, X.3    Hirschy, A.4    Stenbit, A.E.5    Gu, Y.6    Dalton, N.D.7    Yajima, T.8    Lu, Y.9    Knowlton, K.U.10
  • 34
    • 0031799964 scopus 로고    scopus 로고
    • Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis
    • Chen, J., Kubalak, S.W. and Chien, K.R. (1998) Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development, 125, 1943-1949.
    • (1998) Development , vol.125 , pp. 1943-1949
    • Chen, J.1    Kubalak, S.W.2    Chien, K.R.3
  • 36
    • 70449473084 scopus 로고    scopus 로고
    • Skin and heart: une liaison dangereuse
    • Bolling, M.C. and Jonkman, M.F. (2009) Skin and heart: une liaison dangereuse. Exp. Dermatol., 18, 658-668.
    • (2009) Exp. Dermatol. , vol.18 , pp. 658-668
    • Bolling, M.C.1    Jonkman, M.F.2
  • 37
    • 33748056793 scopus 로고    scopus 로고
    • Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies
    • Basso, C., Czarnowska, E., Della Barbera, M., Bauce, B., Beffagna, G., Wlodarska, E.K., Pilichou, K., Ramondo, A., Lorenzon, A., Wozniek, O. et al. (2006) Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies. Eur. Heart J., 27, 1847-1854.
    • (2006) Eur. Heart J. , vol.27 , pp. 1847-1854
    • Basso, C.1    Czarnowska, E.2    Della Barbera, M.3    Bauce, B.4    Beffagna, G.5    Wlodarska, E.K.6    Pilichou, K.7    Ramondo, A.8    Lorenzon, A.9    Wozniek, O.10
  • 39
    • 78349298260 scopus 로고    scopus 로고
    • Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI
    • Chuang, J.S., Zemljic-Harpf, A., Ross, R.S., Frank, L.R., McCulloch, A.D. and Omens, J.H. (2010) Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI. Manag. Reson. Med., 64, 1281-1288.
    • (2010) Manag. Reson. Med. , vol.64 , pp. 1281-1288
    • Chuang, J.S.1    Zemljic-Harpf, A.2    Ross, R.S.3    Frank, L.R.4    McCulloch, A.D.5    Omens, J.H.6
  • 40
    • 33645210987 scopus 로고    scopus 로고
    • Anatomy, echocardiography, and normal right ventricular dimensions
    • Ho, S.Y. and Nihoyannopoulos, P. (2006) Anatomy, echocardiography, and normal right ventricular dimensions. Heart, 92(Suppl 1), i2-13.
    • (2006) Heart , vol.92 , Issue.SUPPL. 1
    • Ho, S.Y.1    Nihoyannopoulos, P.2
  • 43
    • 0041629662 scopus 로고    scopus 로고
    • High prevalence of right ventricular involvement in endurance athletes with ventricular arrhythmias Role of an electrophysiologic study in risk stratification.
    • Heidbuchel, H., Hoogsteen, J., Fagard, R., Vanhees, L., Ector, H., Willems, R. and Van Lierde, J. (2003) High prevalence of right ventricular involvement in endurance athletes with ventricular arrhythmias. Role of an electrophysiologic study in risk stratification. Eur. Heart J., 24, 1473-1480.
    • (2003) Eur. Heart J. , vol.24 , pp. 1473-1480
    • Heidbuchel, H.1    Hoogsteen, J.2    Fagard, R.3    Vanhees, L.4    Ector, H.5    Willems, R.6    Van Lierde, J.7
  • 44
    • 84857362825 scopus 로고    scopus 로고
    • Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias?
    • Mezzano, V. and Sheikh, F. (2012) Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias? Life Sci., 90, 313-321.
    • (2012) Life Sci. , vol.90 , pp. 313-321
    • Mezzano, V.1    Sheikh, F.2
  • 46
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon, A.M., Goodenough, D.A. and Paul, D.L. (1998) Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr. Biol., 8, 295-298.
    • (1998) Curr. Biol. , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 47
    • 0034634288 scopus 로고    scopus 로고
    • High-resolution optical mapping of the right bundle branch in connexin40 knockout mice reveals slow conduction in the specialized conduction system
    • Tamaddon, H.S., Vaidya, D., Simon, A.M., Paul, D.L., Jalife, J. and Morley, G.E. (2000) High-resolution optical mapping of the right bundle branch in connexin40 knockout mice reveals slow conduction in the specialized conduction system. Circ. Res., 87, 929-936.
    • (2000) Circ. Res. , vol.87 , pp. 929-936
    • Tamaddon, H.S.1    Vaidya, D.2    Simon, A.M.3    Paul, D.L.4    Jalife, J.5    Morley, G.E.6
  • 48
    • 0141707855 scopus 로고    scopus 로고
    • Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure
    • Akar, F.G. and Rosenbaum, D.S. (2003) Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure. Circ. Res., 93, 638-645.
    • (2003) Circ. Res. , vol.93 , pp. 638-645
    • Akar, F.G.1    Rosenbaum, D.S.2
  • 51
    • 34347268470 scopus 로고    scopus 로고
    • Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium
    • Camelliti, P., Gallagher, J.O., Kohl, P. and McCulloch, A.D. (2006) Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. Nat. Protoc., 1, 1379-1391.
    • (2006) Nat. Protoc. , vol.1 , pp. 1379-1391
    • Camelliti, P.1    Gallagher, J.O.2    Kohl, P.3    McCulloch, A.D.4
  • 52
  • 56
    • 84856115740 scopus 로고    scopus 로고
    • Signaling during epicardium and coronary vessel development
    • Perez-Pomares, J.M. and de la Pompa, J.L. (2011) Signaling during epicardium and coronary vessel development. Circ. Res., 109, 1429-1442.
    • (2011) Circ. Res. , vol.109 , pp. 1429-1442
    • Perez-Pomares, J.M.1    de la Pompa, J.L.2
  • 58
    • 34848820956 scopus 로고    scopus 로고
    • Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells
    • Oxford, E.M., Musa, H., Maass, K., Coombs, W., Taffet, S.M. and Delmar, M. (2007) Connexin43 remodeling caused by inhibition of plakophilin-2 expression in cardiac cells. Circ. Res., 101, 703-711.
    • (2007) Circ. Res. , vol.101 , pp. 703-711
    • Oxford, E.M.1    Musa, H.2    Maass, K.3    Coombs, W.4    Taffet, S.M.5    Delmar, M.6
  • 60
    • 84894025393 scopus 로고    scopus 로고
    • Impaired N-cadherin-mediated adhesion increases the risk of inducible ventricular arrhythmias in isolated rat hearts
    • Zhu, H., Ding, X., Zou, J., Hou, X. and Cao, K. (2012) Impaired N-cadherin-mediated adhesion increases the risk of inducible ventricular arrhythmias in isolated rat hearts. Scientific Res. Essays, 7, 2983-2991.
    • (2012) Scientific Res. Essays , vol.7 , pp. 2983-2991
    • Zhu, H.1    Ding, X.2    Zou, J.3    Hou, X.4    Cao, K.5
  • 63
    • 0029933362 scopus 로고    scopus 로고
    • Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways.
    • Wollert, K.C., Taga, T., Saito, M., Narazaki, M., Kishimoto, T., Glembotski, C.C., Vernallis, A.B., Heath, J.K., Pennica, D., Wood, W.I. et al. (1996) Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. J. Biol. Chem., 271, 9535-9545.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9535-9545
    • Wollert, K.C.1    Taga, T.2    Saito, M.3    Narazaki, M.4    Kishimoto, T.5    Glembotski, C.C.6    Vernallis, A.B.7    Heath, J.K.8    Pennica, D.9    Wood, W.I.10
  • 64
    • 0022592172 scopus 로고
    • Rapid NMR Imaging of Dynamic Processes Using the FLASII Technique
    • Frahm, J., Haase, A. and Matthaei, D. (1986) Rapid NMR Imaging of Dynamic Processes Using the FLASII Technique. Magn. Reson. Med., 3, 321-327.
    • (1986) Magn. Reson. Med. , vol.3 , pp. 321-327
    • Frahm, J.1    Haase, A.2    Matthaei, D.3
  • 66
    • 0035806899 scopus 로고    scopus 로고
    • Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction
    • Gutstein, D.E., Morley, G.E., Vaidya, D., Liu, F., Chen, F.L., Stuhlmann, H. and Fishman, G.I. (2001) Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction. Circulation, 104, 1194-1199.
    • (2001) Circulation , vol.104 , pp. 1194-1199
    • Gutstein, D.E.1    Morley, G.E.2    Vaidya, D.3    Liu, F.4    Chen, F.L.5    Stuhlmann, H.6    Fishman, G.I.7
  • 68
    • 57449117141 scopus 로고    scopus 로고
    • An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice
    • Sheikh, F., Raskin, A., Chu, P.H., Lange, S., Domenighetti, A.A., Zheng, M., Liang, X., Zhang, T., Yajima, T., Gu, Y. et al. (2008) An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J. Clin. Invest., 118, 3870-3880.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3870-3880
    • Sheikh, F.1    Raskin, A.2    Chu, P.H.3    Lange, S.4    Domenighetti, A.A.5    Zheng, M.6    Liang, X.7    Zhang, T.8    Yajima, T.9    Gu, Y.10
  • 69
    • 21044437270 scopus 로고    scopus 로고
    • Microstructured cocultures of cardiac myocytes and fibroblasts: a two-dimensional in vitro model of cardiac tissue
    • Camelliti, P., McCulloch, A.D. and Kohl, P. (2005) Microstructured cocultures of cardiac myocytes and fibroblasts: a two-dimensional in vitro model of cardiac tissue. Microsc Microanal., 11, 249-259.
    • (2005) Microsc Microanal. , vol.11 , pp. 249-259
    • Camelliti, P.1    McCulloch, A.D.2    Kohl, P.3
  • 70
    • 0034352213 scopus 로고    scopus 로고
    • Model-based analysis of optically mapped epicardial activation patterns and conduction velocity
    • Sung, D., Omens, J.H. and McCulloch, A.D. (2000) Model-based analysis of optically mapped epicardial activation patterns and conduction velocity. Ann. Biomed. Eng., 28, 1085-1092.
    • (2000) Ann. Biomed. Eng. , vol.28 , pp. 1085-1092
    • Sung, D.1    Omens, J.H.2    McCulloch, A.D.3


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