α-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture

Circulation

Volumn 114, Issue 10, 2006, Pages 1046-1055

  Sheikh, Farah ^a   Chen, Yinghong ^a   Liang, Xingqun ^a   Hirschy, Alain ^b   Stenbit, Antine E ^a   Gu, Yusu ^a   Dalton, Nancy D ^a   Yajima, Toshitaka ^a   Lu, Yingchun ^a   Knowlton, Kirk U ^a   Peterson, Kirk L ^a   Perriard, Jean Claude ^b   Chen, Ju ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardiomyopathy; Death, sudden; Genes; Myocytes; Structure

Indexed keywords

ALPHA CATENIN; ALPHA E CATENIN; CADHERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CELL JUNCTION; CELL ULTRASTRUCTURE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CYTOSKELETON; DISEASE PREDISPOSITION; HEART MUSCLE CELL; HEART RIGHT VENTRICLE; HEART RUPTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALPHA CATENIN; ANIMALS; CARDIOMYOPATHY, DILATED; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; MICE; MICE, KNOCKOUT; MUSCLE CELLS; MYOCARDIAL INFARCTION; MYOCARDIUM; PROTEINS; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 33748486911     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.634469     Document Type: Article

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