메뉴 건너뛰기




Volumn 26, Issue 2, 2014, Pages 58-67

High-fat diet induces leptin resistance in leptin-deficient mice

Author keywords

Energy and glucose homeostasis; Hypothalamus; Inflammation; JNK pathway

Indexed keywords

ENERGY AND GLUCOSE HOMEOSTASIS; HYPOTHALAMUS; INFLAMMATION; JNK PATHWAY;

EID: 84894082286     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12131     Document Type: Article
Times cited : (83)

References (36)
  • 2
    • 0030467446 scopus 로고    scopus 로고
    • The OB protein (leptin) pathway - a link between adipose tissue mass and central neural networks
    • Campfield LA, Smith FJ, Burn P. The OB protein (leptin) pathway - a link between adipose tissue mass and central neural networks. Horm Metab Res 1996; 28: 619-632.
    • (1996) Horm Metab Res , vol.28 , pp. 619-632
    • Campfield, L.A.1    Smith, F.J.2    Burn, P.3
  • 3
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 7
    • 0029962467 scopus 로고    scopus 로고
    • Correction of obesity and diabetes in genetically obese mice by leptin gene therapy
    • Muzzin P, Eisensmith RC, Copeland KC, Woo SL. Correction of obesity and diabetes in genetically obese mice by leptin gene therapy. Proc Natl Acad Sci USA 1996; 93: 14804-14808.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14804-14808
    • Muzzin, P.1    Eisensmith, R.C.2    Copeland, K.C.3    Woo, S.L.4
  • 11
    • 52949140814 scopus 로고    scopus 로고
    • Making insulin-deficient type 1 diabetic rodents thrive without insulin
    • Yu X, Park BH, Wang MY, Wang ZV, Unger RH. Making insulin-deficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci USA 2008; 105: 14070-14075.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14070-14075
    • Yu, X.1    Park, B.H.2    Wang, M.Y.3    Wang, Z.V.4    Unger, R.H.5
  • 16
    • 0035313069 scopus 로고    scopus 로고
    • Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation
    • Hubschle T, Thom E, Watson A, Roth J, Klaus S, Meyerhof W. Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation. J Neurosci 2001; 21: 2413-2424.
    • (2001) J Neurosci , vol.21 , pp. 2413-2424
    • Hubschle, T.1    Thom, E.2    Watson, A.3    Roth, J.4    Klaus, S.5    Meyerhof, W.6
  • 17
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek C, Uotani S, da SB, Flier JS. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 1997; 272: 32686-32695.
    • (1997) J Biol Chem , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    da, S.B.3    Flier, J.S.4
  • 20
    • 0038747134 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin
    • Munzberg H, Huo L, Nillni EA, Hollenberg AN, Bjorbaek C. Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology 2003; 144: 2121-2131.
    • (2003) Endocrinology , vol.144 , pp. 2121-2131
    • Munzberg, H.1    Huo, L.2    Nillni, E.A.3    Hollenberg, A.N.4    Bjorbaek, C.5
  • 21
    • 9244219587 scopus 로고    scopus 로고
    • Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
    • Munzberg H, Flier JS, Bjorbaek C. Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 2004; 145: 4880-4889.
    • (2004) Endocrinology , vol.145 , pp. 4880-4889
    • Munzberg, H.1    Flier, J.S.2    Bjorbaek, C.3
  • 23
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995; 269: 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 24
    • 0033931981 scopus 로고    scopus 로고
    • Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
    • El-Haschimi K, Pierroz DD, Hileman SM, Bjorbaek C, Flier JS. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 2000; 105: 1827-1832.
    • (2000) J Clin Invest , vol.105 , pp. 1827-1832
    • El-Haschimi, K.1    Pierroz, D.D.2    Hileman, S.M.3    Bjorbaek, C.4    Flier, J.S.5
  • 26
    • 60849120123 scopus 로고    scopus 로고
    • HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms
    • White CL, Whittington A, Barnes MJ, Wang Z, Bray GA, Morrison CD. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab 2009; 296: E291-E299.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • White, C.L.1    Whittington, A.2    Barnes, M.J.3    Wang, Z.4    Bray, G.A.5    Morrison, C.D.6
  • 27
  • 28
    • 0037244070 scopus 로고    scopus 로고
    • Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations
    • Banks WA. Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations. Curr Pharm Des 2003; 9: 801-809.
    • (2003) Curr Pharm Des , vol.9 , pp. 801-809
    • Banks, W.A.1
  • 30
    • 34247511618 scopus 로고    scopus 로고
    • TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - effects on leptin and insulin signaling pathways
    • Romanatto T, Cesquini M, Amaral ME, Roman EA, Moraes JC, Torsoni MA, Cruz-Neto AP, Velloso LA. TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient - effects on leptin and insulin signaling pathways. Peptides 2007; 28: 1050-1058.
    • (2007) Peptides , vol.28 , pp. 1050-1058
    • Romanatto, T.1    Cesquini, M.2    Amaral, M.E.3    Roman, E.A.4    Moraes, J.C.5    Torsoni, M.A.6    Cruz-Neto, A.P.7    Velloso, L.A.8
  • 31
    • 0032544729 scopus 로고    scopus 로고
    • Reconstitution of IL6-inducible differentiation of a myeloid leukemia cell line by activated Stat factors
    • Piekorz R, Schlierf B, Burger R, Hocke GM. Reconstitution of IL6-inducible differentiation of a myeloid leukemia cell line by activated Stat factors. Biochem Biophys Res Commun 1998; 250: 436-443.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 436-443
    • Piekorz, R.1    Schlierf, B.2    Burger, R.3    Hocke, G.M.4
  • 32
    • 0034984796 scopus 로고    scopus 로고
    • Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo
    • Rizk NM, Stammsen D, Preibisch G, Eckel J. Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo. Endocrinology 2001; 142: 3027-3032.
    • (2001) Endocrinology , vol.142 , pp. 3027-3032
    • Rizk, N.M.1    Stammsen, D.2    Preibisch, G.3    Eckel, J.4
  • 34
    • 78049297525 scopus 로고    scopus 로고
    • Lecture Outstanding Scientific Achievement Award deconstructing leptin: from signals to circuits
    • Myers MG Jr. Lecture Outstanding Scientific Achievement Award deconstructing leptin: from signals to circuits. Diabetes 2010; 59: 2708-2714.
    • (2010) Diabetes , vol.59 , pp. 2708-2714
    • Myers Jr., M.G.1
  • 36
    • 84876325578 scopus 로고    scopus 로고
    • Acute inhibition of central c-Jun N-terminal kinase restores hypothalamic insulin signalling and alleviates glucose intolerance in diabetic mice
    • Benzler GK, Ganjam J, Legler K, Steger J, Stohrz S, Kruger M, Tups A. Acute inhibition of central c-Jun N-terminal kinase restores hypothalamic insulin signalling and alleviates glucose intolerance in diabetic mice. J Neuroendocrinol 2013; 25: 446-454.
    • (2013) J Neuroendocrinol , vol.25 , pp. 446-454
    • Benzler, G.K.1    Ganjam, J.2    Legler, K.3    Steger, J.4    Stohrz, S.5    Kruger, M.6    Tups, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.