Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former

International Journal of Pharmaceutics

Volumn 420, Issue 1, 2011, Pages 34-42

  Yamasaki, Keishi ^a   Kwok, Philip Chi Lip ^b   Fukushige, Kaori ^c   Prud'Homme, Robert K ^d   Chan, Hak Kim ^b  

^a SOJO UNIVERSITY   (Japan)

^b UNIVERSITY OF SYDNEY   (Australia)

^c NAGOYA CITY UNIVERSITY   (Japan)

^d Princeton University   (United States)

Author keywords

Cyclosporine A; Dissolution; Dry powder aerosol; Mannitol; Nanoparticles; Pulmonary drug delivery

Indexed keywords

CYCLOSPORIN A; MANNITOL; NANOPARTICLE;

AEROSOL; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG FORMULATION; DRUG SOLUBILITY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRECIPITATION; PRIORITY JOURNAL; SPRAY DRYING; SURFACE PROPERTY; SUSPENSION;

ADMINISTRATION, INHALATION; AEROSOLS; CHEMICAL PRECIPITATION; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; CYCLOSPORINE; DRUG CARRIERS; DRUG COMPOUNDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNOSUPPRESSIVE AGENTS; KINETICS; MANNITOL; NANOPARTICLES; NANOTECHNOLOGY; POWDERS; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 80054697360     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.010     Document Type: Article

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