-
1
-
-
0026733643
-
Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion
-
Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE. Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J Biol Chem 1992; 267: 5802-5810.
-
(1992)
J Biol Chem
, vol.267
, pp. 5802-5810
-
-
Prentki, M.1
Vischer, S.2
Glennon, M.C.3
Regazzi, R.4
Deeney, J.T.5
Corkey, B.E.6
-
2
-
-
0142093526
-
Fatty acid metabolism and insulin secretion in pancreatic β cells
-
Yaney GC, Corkey BE. Fatty acid metabolism and insulin secretion in pancreatic β cells. Diabetologia 2003; 46: 1297-1312.
-
(2003)
Diabetologia
, vol.46
, pp. 1297-1312
-
-
Yaney, G.C.1
Corkey, B.E.2
-
3
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
-
Itoh Y, Kawamata Y, Harada M et al. Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40. Nature 2003; 422: 173-176.
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
-
4
-
-
0037838892
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
-
Briscoe CP, Tadayyon M et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 2003; 278: 11303-11311.
-
(2003)
J Biol Chem
, vol.278
, pp. 11303-11311
-
-
Briscoe, C.P.1
Tadayyon, M.2
-
5
-
-
0346041542
-
Progress in methodology. Improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors
-
Kotarsky K, Nilsson NE, Olde B, Owman C. Progress in methodology. Improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors. Pharmacol Toxicol 2003; 93: 249-258.
-
(2003)
Pharmacol Toxicol
, vol.93
, pp. 249-258
-
-
Kotarsky, K.1
Nilsson, N.E.2
Olde, B.3
Owman, C.4
-
6
-
-
25144470087
-
Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet β-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release
-
Fujiwara K, Maekawa F, Yada T. Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet β-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release. Am J Physiol Endocrinol Metab 2005; 289: E670-677.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Fujiwara, K.1
Maekawa, F.2
Yada, T.3
-
8
-
-
33646395425
-
Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic β cells and implications for insulin secretion
-
Tomita T, Masuzaki H, Iwakura H et al. Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic β cells and implications for insulin secretion. Diabetologia 2006; 49: 962-968.
-
(2006)
Diabetologia
, vol.49
, pp. 962-968
-
-
Tomita, T.1
Masuzaki, H.2
Iwakura, H.3
-
10
-
-
25144433441
-
Role of GPR40 in fatty acid action on the β cell line INS-1E
-
Shapiro H, Shachar S, Sekler I, Hershfinkel M, Walker MD. Role of GPR40 in fatty acid action on the β cell line INS-1E. Biochem Biophys Res Commun 2005; 335: 97-104.
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 97-104
-
-
Shapiro, H.1
Shachar, S.2
Sekler, I.3
Hershfinkel, M.4
Walker, M.D.5
-
11
-
-
30944455097
-
The free fatty acid receptor GPR40 generates excitement in pancreatic β-cells
-
Gromada J. The free fatty acid receptor GPR40 generates excitement in pancreatic β-cells. Endocrinology 2006; 147: 672-673.
-
(2006)
Endocrinology
, vol.147
, pp. 672-673
-
-
Gromada, J.1
-
12
-
-
33751520308
-
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40
-
Schnell S, Schaefer M, Schofl C. Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40. Mol Cell Endocrinol 2007; 263(1-2): 173-180.
-
(2007)
Mol Cell Endocrinol
, vol.263
, Issue.1-2
, pp. 173-180
-
-
Schnell, S.1
Schaefer, M.2
Schofl, C.3
-
13
-
-
50949128408
-
Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice
-
Tan CP, Feng Y, Zhou YP et al. Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice. Diabetes 2008; 57: 2211-2219.
-
(2008)
Diabetes
, vol.57
, pp. 2211-2219
-
-
Tan, C.P.1
Feng, Y.2
Zhou, Y.P.3
-
14
-
-
33745607930
-
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules
-
Briscoe CP, Peat AJ, McKeown SC et al. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol 2006; 148: 619-628.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 619-628
-
-
Briscoe, C.P.1
Peat, A.J.2
McKeown, S.C.3
-
15
-
-
34250879091
-
Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists
-
Song F, Lu S, Gunnet J et al. Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists. J Med Chem 2007; 50: 2807-2817.
-
(2007)
J Med Chem
, vol.50
, pp. 2807-2817
-
-
Song, F.1
Lu, S.2
Gunnet, J.3
-
16
-
-
65549114432
-
Overexpression of GPR40 in pancreatic β-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice
-
Nagasumi K, Esaki R, Iwachidow K et al. Overexpression of GPR40 in pancreatic β-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. Diabetes 2009; 58: 1067-1076.
-
(2009)
Diabetes
, vol.58
, pp. 1067-1076
-
-
Nagasumi, K.1
Esaki, R.2
Iwachidow, K.3
-
17
-
-
80053138180
-
TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats
-
Tsujihata Y, Ito R, Suzuki M et al. TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats. J Pharmacol Exp Ther 2011; 339: 228-237.
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 228-237
-
-
Tsujihata, Y.1
Ito, R.2
Suzuki, M.3
-
18
-
-
0032478314
-
Fatty acid-induced β cell apoptosis: a link between obesity and diabetes
-
Shimabukuro M, Zhou YT, Levi M, Unger RH. Fatty acid-induced β cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci USA 1998; 95: 2498-2502.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.T.2
Levi, M.3
Unger, R.H.4
-
19
-
-
0036153256
-
Minireview: secondary β-cell failure in type 2 diabetes-a convergence of glucotoxicity and lipotoxicity
-
Poitout V, Robertson RP. Minireview: secondary β-cell failure in type 2 diabetes-a convergence of glucotoxicity and lipotoxicity. Endocrinology 2002; 143: 339-342.
-
(2002)
Endocrinology
, vol.143
, pp. 339-342
-
-
Poitout, V.1
Robertson, R.P.2
-
20
-
-
0026757632
-
Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations
-
Robertson RP, Zhang HJ, Pyzdrowski KL, Walseth TF. Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations. J Clin Invest 1992; 90: 320-325.
-
(1992)
J Clin Invest
, vol.90
, pp. 320-325
-
-
Robertson, R.P.1
Zhang, H.J.2
Pyzdrowski, K.L.3
Walseth, T.F.4
-
21
-
-
39749147110
-
Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
-
Muoio DM, Newgard CB. Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol 2008; 9: 193-205.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
22
-
-
20944433543
-
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
-
Steneberg P, Rubins N, Bartoov-Shifman R, Walker MD, Edlund H. The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab 2005; 1: 245-258.
-
(2005)
Cell Metab
, vol.1
, pp. 245-258
-
-
Steneberg, P.1
Rubins, N.2
Bartoov-Shifman, R.3
Walker, M.D.4
Edlund, H.5
-
23
-
-
58149100292
-
Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease
-
Lan H, Hoos LM, Liu L et al. Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease. Diabetes 2008; 57: 2999-3006.
-
(2008)
Diabetes
, vol.57
, pp. 2999-3006
-
-
Lan, H.1
Hoos, L.M.2
Liu, L.3
-
24
-
-
34047177401
-
GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo
-
Latour MG, Alquier T, Oseid E et al. GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes 2007; 56: 1087-1094.
-
(2007)
Diabetes
, vol.56
, pp. 1087-1094
-
-
Latour, M.G.1
Alquier, T.2
Oseid, E.3
-
25
-
-
52249093427
-
The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding
-
Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, Poitout V. The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes 2008; 57: 2432-2437.
-
(2008)
Diabetes
, vol.57
, pp. 2432-2437
-
-
Kebede, M.1
Alquier, T.2
Latour, M.G.3
Semache, M.4
Tremblay, C.5
Poitout, V.6
-
26
-
-
70350561694
-
Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets
-
Alquier T, Peyot ML, Latour MG et al. Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes 2009; 58: 2607-2615.
-
(2009)
Diabetes
, vol.58
, pp. 2607-2615
-
-
Alquier, T.1
Peyot, M.L.2
Latour, M.G.3
-
28
-
-
84877623304
-
y mice
-
Shima AAF, Shafrir E, eds. Amsterdam: Harwood Academic Publishers
-
y mice. In: Shima AAF, Shafrir E, eds. Animal Models of Diabetes. A Primer. Amsterdam: Harwood Academic Publishers, 2001; 129-142.
-
(2001)
Animal Models of Diabetes. A Primer
, pp. 129-142
-
-
Taketomi, S.1
Ikeda, H.2
-
29
-
-
0029742921
-
Regulation of obese gene expression in KK mice and congenic lethal yellow obese KKAy mice
-
Hayase M, Ogawa Y, Katsuura G, Shintaku H, Hosoda K, Nakao K. Regulation of obese gene expression in KK mice and congenic lethal yellow obese KKAy mice. Am J Physiol 1996; 271(2 Pt 1): E333-339.
-
(1996)
Am J Physiol
, vol.271
, Issue.2 PART 1
-
-
Hayase, M.1
Ogawa, Y.2
Katsuura, G.3
Shintaku, H.4
Hosoda, K.5
Nakao, K.6
-
30
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
31
-
-
0022993678
-
Isolation of rat pancreatic islets by ductal injection of collagenase
-
Sutton R, Peters M, McShane P, Gray DW, Morris PJ. Isolation of rat pancreatic islets by ductal injection of collagenase. Transplantation 1986; 42: 689-691.
-
(1986)
Transplantation
, vol.42
, pp. 689-691
-
-
Sutton, R.1
Peters, M.2
McShane, P.3
Gray, D.W.4
Morris, P.J.5
-
32
-
-
0032960430
-
Lipid infusion lowers sympathetic nervous activity and leads to increased β-cell responsiveness to glucose
-
Magnan C, Collins S, Berthault MF et al. Lipid infusion lowers sympathetic nervous activity and leads to increased β-cell responsiveness to glucose. J Clin Invest 1999; 103: 413-419.
-
(1999)
J Clin Invest
, vol.103
, pp. 413-419
-
-
Magnan, C.1
Collins, S.2
Berthault, M.F.3
-
33
-
-
12144291143
-
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli
-
Roduit R, Nolan C, Alarcon C et al. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes 2004; 53: 1007-1019.
-
(2004)
Diabetes
, vol.53
, pp. 1007-1019
-
-
Roduit, R.1
Nolan, C.2
Alarcon, C.3
-
34
-
-
19944434042
-
Studies of relationships between variation of the human G protein-coupled receptor 40 gene and type 2 diabetes and insulin release
-
Hamid YH, Vissing H, Holst B et al. Studies of relationships between variation of the human G protein-coupled receptor 40 gene and type 2 diabetes and insulin release. Diabet Med 2005; 22: 74-80.
-
(2005)
Diabet Med
, vol.22
, pp. 74-80
-
-
Hamid, Y.H.1
Vissing, H.2
Holst, B.3
-
35
-
-
13844266013
-
GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men
-
Ogawa T, Hirose H, Miyashita K, Saito I, Saruta T. GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men. Metabolism 2005; 54: 296-299.
-
(2005)
Metabolism
, vol.54
, pp. 296-299
-
-
Ogawa, T.1
Hirose, H.2
Miyashita, K.3
Saito, I.4
Saruta, T.5
-
36
-
-
51649104136
-
Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization
-
Vettor R, Granzotto M, De Stefani D et al. Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization. J Clin Endocrinol Metab 2008; 93: 3541-3550.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3541-3550
-
-
Vettor, R.1
Granzotto, M.2
De Stefani, D.3
|