Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death

Chemico-Biological Interactions

Volumn 212, Issue 1, 2014, Pages 20-29

  Reis, Felippe H Z ^a   Pardo Andreu, Gilberto L ^a,b   Nuñez Figueredo, Yanier ^c   Cuesta Rubio, Osmany ^b   Marín Prida, Javier ^b   Uyemura, Sérgio A ^a   Curti, Carlos ^a   Alberici, Luciane C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DE FARMACIA Y ALIMENTOS   (Cuba)

^c Centro para las Investigaciones y Desarrollo de Medicamentos   (Cuba)

Author keywords

Clusianone; HepG2 cell death; Mitochondria; Nemorosone; Protonophore; Uncoupler

Indexed keywords

CLUSIANONE; HEPG2 CELL DEATH; MITOCHONDRIA; NEMOROSONE; PROTONOPHORE; UNCOUPLER;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; BENZOPHENONES; BICYCLO COMPOUNDS; BIOLOGICAL PRODUCTS; BIOLOGICAL TRANSPORT; CALCIUM; CELL DEATH; CELL RESPIRATION; HEP G2 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; NAD; OSMOTIC PRESSURE; RATS; REACTIVE OXYGEN SPECIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; UNCOUPLING AGENTS;

EID: 84894030745     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.01.015     Document Type: Article

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