Aromatic interactions impact ligand binding and function at serotonin 5-HT2C G protein-coupled receptors: Receptor homology modelling, ligand docking, and molecular dynamics results validated by experimental studies

Molecular Physics

Volumn 112, Issue 3-4, 2014, Pages 398-407

  Córdova Sintjago, Tania ^a   Villa, Nancy ^a   Fang, Lijuan ^a   Booth, Raymond G ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Aromatic interactions; Docking; Drug design; F6.51; F6.52; GPCR; Homology modelling; Molecular dynamics; Serotonin 5 HT2C; W6.48

Indexed keywords

AROMATIC INTERACTIONS; DRUG DESIGN; F6.51; F6.52; GPCR; HOMOLOGY MODELLING; SEROTONIN 5-HT2C; W6.48;

AROMATIC COMPOUNDS; DOCKING; MOLECULAR DYNAMICS;

LIGANDS;

EID: 84893871865     PISSN: 00268976     EISSN: 13623028     Source Type: Journal    
DOI: 10.1080/00268976.2013.833656     Document Type: Conference Paper

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