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Angewandte Chemie - International Edition

Volumn 53, Issue 8, 2014, Pages 2235-2239

Pseudilins: Halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD

(13) Kunfermann, Andrea b Witschel, Matthias c Illarionov, Boris d Martin, René e Rottmann, Matthias f,g Höffken, H Wolfgang c Seet, Michael a Eisenreich, Wolfgang b Knölker, Hans Joachim e Fischer, Markus d Bacher, Adelbert d Groll, Michael b Diederich, François a

a ETH ZURICH (Switzerland)

b TECHNICAL UNIVERSITY OF MUNICH (Germany)

c BASF SE (Germany)

d UNIVERSITY OF HAMBURG (Germany)

e DRESDEN UNIVERSITY OF TECHNOLOGY (Germany)

f SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE (Switzerland)

g UNIVERSITY OF BASEL (Switzerland)

Author keywords

allosteric inhibition; antiinfectives; drug discovery; halogen bonding; herbicides; pseudilins

Indexed keywords

ALLOSTERIC INHIBITION; ANTI-INFECTIVES; DRUG DISCOVERY; HALOGEN BONDING; PSEUDILINS;

BIOCHEMISTRY; HALOGENATION; HERBICIDES; WEED CONTROL;

ENZYMES;

ALKALOID; BIOLOGICAL PRODUCT; HERBICIDE; MEVALONIC ACID; MULTIENZYME COMPLEX; PROTOZOAL PROTEIN; VEGETABLE PROTEIN;

ALLOSTERISM; ANTAGONISTS AND INHIBITORS; ARABIDOPSIS; BINDING SITE; CHEMISTRY; ENZYMOLOGY; HALOGENATION; METABOLISM; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM VIVAX; PROTEIN TERTIARY STRUCTURE;

ALKALOIDS; ALLOSTERIC REGULATION; ALLOSTERIC SITE; ARABIDOPSIS; BINDING SITES; BIOLOGICAL PRODUCTS; HALOGENATION; HERBICIDES; MAGNETIC RESONANCE SPECTROSCOPY; MEVALONIC ACID; MOLECULAR DYNAMICS SIMULATION; MULTIENZYME COMPLEXES; PLANT PROTEINS; PLASMODIUM VIVAX; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS;

EID: 84893869668 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201309557 Document Type: Article

Times cited : (53)

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