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Volumn 5, Issue 1, 2014, Pages 173-184

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death

Author keywords

Autophagy; Ras; Signal transduction; Transformation

Indexed keywords

CASPASE 3; CHLOROQUINE; CYTOCHROME C; SALIRASIB; SURVIVIN; ANTINEOPLASTIC AGENT; FARNESOL; RAS PROTEIN; SALICYLIC ACID DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

EID: 84893837324     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1500     Document Type: Article
Times cited : (14)

References (41)
  • 1
    • 0032493812 scopus 로고    scopus 로고
    • Increasing complexity of the Ras signaling pathway
    • Vojtek AB and Der CJ. Increasing complexity of the Ras signaling pathway. The Journal of biological chemistry. 1998; 273(32):19925-19928.
    • (1998) The Journal of biological chemistry. , vol.273 , Issue.32 , pp. 19925-19928
    • Vojtek, A.B.1    Der, C.J.2
  • 4
    • 0019960812 scopus 로고
    • A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
    • Reddy EP, Reynolds RK, Santos E and Barbacid M. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature. 1982; 300(5888):149-152.
    • (1982) Nature. , vol.300 , Issue.5888 , pp. 149-152
    • Reddy, E.P.1    Reynolds, R.K.2    Santos, E.3    Barbacid, M.4
  • 6
    • 78649487698 scopus 로고    scopus 로고
    • Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
    • Vigil D, Cherfils J, Rossman KL and Der CJ. Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? Nat Rev Cancer. 2010; 10(12):842-857.
    • (2010) Nat Rev Cancer. , vol.10 , Issue.12 , pp. 842-857
    • Vigil, D.1    Cherfils, J.2    Rossman, K.L.3    Der, C.J.4
  • 10
  • 12
    • 1542347803 scopus 로고    scopus 로고
    • The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro
    • McPherson RA, Conaway MC, Gregory CW, Yue W and Santen RJ. The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro. Prostate. 2004; 58(4):325-334.
    • (2004) Prostate. , vol.58 , Issue.4 , pp. 325-334
    • McPherson, R.A.1    Conaway, M.C.2    Gregory, C.W.3    Yue, W.4    Santen, R.J.5
  • 13
    • 33745950061 scopus 로고    scopus 로고
    • Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells
    • Erlich S, Tal-Or P, Liebling R, Blum R, Karunagaran D, Kloog Y and Pinkas-Kramarski R. Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells. Biochem Pharmacol. 2006; 72(4):427-436.
    • (2006) Biochem Pharmacol. , vol.72 , Issue.4 , pp. 427-436
    • Erlich, S.1    Tal-Or, P.2    Liebling, R.3    Blum, R.4    Karunagaran, D.5    Kloog, Y.6    Pinkas-Kramarski, R.7
  • 14
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ and Emr SD. Autophagy as a regulated pathway of cellular degradation. Science. 2000; 290(5497):1717-1721.
    • (2000) Science. , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 15
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang C-W and J KD. The molecular mechanism of autophagy. Mol Med. 2003; 9:65-76.
    • (2003) Mol Med. , vol.9 , pp. 65-76
    • Wang, C.-W.1    Klionsky, D.J.2
  • 16
    • 0036066121 scopus 로고    scopus 로고
    • Autophagy in neurons: a review
    • Larsen KE and Sulzer D. Autophagy in neurons: a review. Histol Histopathol. 2002; 17(3):897-908.
    • (2002) Histol Histopathol. , vol.17 , Issue.3 , pp. 897-908
    • Larsen, K.E.1    Sulzer, D.2
  • 17
    • 0037451783 scopus 로고    scopus 로고
    • Autophagy: a barrier or an adaptive response to cancer
    • Ogier-Denis E and Codogno P. Autophagy: a barrier or an adaptive response to cancer. Biochim Biophys Acta. 2003; 603:113-128.
    • (2003) Biochim Biophys Acta. , vol.603 , pp. 113-128
    • Ogier-Denis, E.1    Codogno, P.2
  • 20
    • 0027315687 scopus 로고
    • Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum
    • Slater AF. Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum. Pharmacol Ther. 1993; 57(2-3):203-235.
    • (1993) Pharmacol Ther. , vol.57 , Issue.2-3 , pp. 203-235
    • Slater, A.F.1
  • 23
    • 84859562694 scopus 로고    scopus 로고
    • Targeting autophagy addiction in cancer
    • Mancias JD and Kimmelman AC. Targeting autophagy addiction in cancer. Oncotarget. 2011; 2(12):1302-1306.
    • (2011) Oncotarget. , vol.2 , Issue.12 , pp. 1302-1306
    • Mancias, J.D.1    Kimmelman, A.C.2
  • 25
    • 84864805916 scopus 로고    scopus 로고
    • Autophagy and cancer - issues we need to digest
    • Liu EY and Ryan KM. Autophagy and cancer - issues we need to digest. J Cell Sci. 2012; 125(Pt 10):2349-2358.
    • (2012) J Cell Sci , vol.125 , Issue.PART 10 , pp. 2349-2358
    • Liu, E.Y.1    Ryan, K.M.2
  • 26
    • 84864960912 scopus 로고    scopus 로고
    • Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger
    • Mathew R and White E. Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger. Cold Spring Harbor symposia on quantitative biology. 2011; 76:389-396.
    • (2011) Cold Spring Harbor symposia on quantitative biology. , vol.76 , pp. 389-396
    • Mathew, R.1    White, E.2
  • 28
    • 0037142613 scopus 로고    scopus 로고
    • Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers
    • Laghi L, Orbetegli O, Bianchi P, Zerbi A, Di Carlo V, Boland CR and Malesci A. Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers. Oncogene. 2002; 21(27):4301-4306.
    • (2002) Oncogene. , vol.21 , Issue.27 , pp. 4301-4306
    • Laghi, L.1    Orbetegli, O.2    Bianchi, P.3    Zerbi, A.4    Di Carlo, V.5    Boland, C.R.6    Malesci, A.7
  • 30
    • 33644611292 scopus 로고    scopus 로고
    • Evaluating response to antineoplastic drug combinations in tissue culture models
    • Reynolds CP and Maurer BJ. Evaluating response to antineoplastic drug combinations in tissue culture models. Methods Mol Med. 2005; 110:173-183.
    • (2005) Methods Mol Med. , vol.110 , pp. 173-183
    • Reynolds, C.P.1    Maurer, B.J.2
  • 33
    • 79953306808 scopus 로고    scopus 로고
    • Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
    • Elgendy M, Sheridan C, Brumatti G and Martin SJ. Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival. Mol Cell. 2011; 42(1):23-35.
    • (2011) Mol Cell. , vol.42 , Issue.1 , pp. 23-35
    • Elgendy, M.1    Sheridan, C.2    Brumatti, G.3    Martin, S.J.4
  • 34
    • 70849093011 scopus 로고    scopus 로고
    • The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras
    • Byun JY, Yoon CH, An S, Park IC, Kang CM, Kim MJ and Lee SJ. The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras. Carcinogenesis. 2009; 30(11):1880-1888.
    • (2009) Carcinogenesis. , vol.30 , Issue.11 , pp. 1880-1888
    • Byun, J.Y.1    Yoon, C.H.2    An, S.3    Park, I.C.4    Kang, C.M.5    Kim, M.J.6    Lee, S.J.7
  • 35
    • 77949324323 scopus 로고    scopus 로고
    • Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells
    • Yoo BH, Wu X, Li Y, Haniff M, Sasazuki T, Shirasawa S, Eskelinen EL and Rosen KV. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells. The Journal of biological chemistry. 2010; 285(8):5438-5449.
    • (2010) The Journal of biological chemistry. , vol.285 , Issue.8 , pp. 5438-5449
    • Yoo, B.H.1    Wu, X.2    Li, Y.3    Haniff, M.4    Sasazuki, T.5    Shirasawa, S.6    Eskelinen, E.L.7    Rosen, K.V.8
  • 36
    • 2542628931 scopus 로고    scopus 로고
    • Ras is involved in the negative control of autophagy through the class I PI3-kinase
    • Furuta S, Hidaka E, Ogata A, Yokota S and Kamata T. Ras is involved in the negative control of autophagy through the class I PI3-kinase. Oncogene. 2004; 23(22):3898-3904.
    • (2004) Oncogene. , vol.23 , Issue.22 , pp. 3898-3904
    • Furuta, S.1    Hidaka, E.2    Ogata, A.3    Yokota, S.4    Kamata, T.5
  • 38
    • 22344444616 scopus 로고    scopus 로고
    • Does autophagy contribute to cell death?
    • Debnath J, Baehrecke EH and Kroemer G. Does autophagy contribute to cell death? Autophagy. 2005; 1(2):66-74.
    • (2005) Autophagy. , vol.1 , Issue.2 , pp. 66-74
    • Debnath, J.1    Baehrecke, E.H.2    Kroemer, G.3
  • 39
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: dual roles in life and death?
    • Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol. 2005; 6(6):505-510.
    • (2005) Nat Rev Mol Cell Biol. , vol.6 , Issue.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 40
    • 33645115547 scopus 로고    scopus 로고
    • Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial
    • Sotelo J, Briceno E and Lopez-Gonzalez MA. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2006; 144(5):337-343.
    • (2006) Ann Intern Med. , vol.144 , Issue.5 , pp. 337-343
    • Sotelo, J.1    Briceno, E.2    Lopez-Gonzalez, M.A.3
  • 41
    • 84871940714 scopus 로고    scopus 로고
    • Chloroquine in cancer therapy: a double-edged sword of autophagy
    • Kimura T, Takabatake Y, Takahashi A and Isaka Y. Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res. 2013; 73(1):3-7.
    • (2013) Cancer Res. , vol.73 , Issue.1 , pp. 3-7
    • Kimura, T.1    Takabatake, Y.2    Takahashi, A.3    Isaka, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.