Stringent structural requirements for anti-Ras activity of S-prenyl analogues

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1406, Issue 1, 1998, Pages 40-50

  Aharonson, Ziporet ^a   Gana Weisz, Mali ^a   Varsano, Tal ^a   Haklai, Roni ^a   Marciano, Daniele ^b   Kloog, Yoel ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

Author keywords

EJ cell line; Farnesyl analog; Geranylgeranyl analog; Ras oncoproteins; Ras antagonists

Indexed keywords

ANTINEOPLASTIC AGENT; FARNESYL DERIVATIVE; GERANYL DERIVATIVE; PRENYL DERIVATIVE; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DRUG DESIGN; DRUG DEVELOPMENT; DRUG SYNTHESIS; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN STRUCTURE, FUNCTION AND VARIABILITY; RAT; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL DIVISION; CELL LINE; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FARNESOL; RAS PROTEINS; RATS; SALICYLIC ACIDS; TRANSFECTION;

EID: 0032570931     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(97)00077-X     Document Type: Article

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