-
1
-
-
0029889577
-
Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase
-
1:CAS:528:DyaK28XjsFGku74%3D 8665499
-
Chmura SJ, Nodzenski E, Weichselbaum RR, Quintans J. Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase. Cancer Res. 1996;56:2711-4.
-
(1996)
Cancer Res
, vol.56
, pp. 2711-2714
-
-
Chmura, S.J.1
Nodzenski, E.2
Weichselbaum, R.R.3
Quintans, J.4
-
2
-
-
0033961302
-
In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo
-
Chamura SJ, Dolan ME, Cha A, Mauceri HJ, Kufe DW, Weichselbaum RR. In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Clin Cancer Res. 2000;6:737-42.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 737-742
-
-
Chamura, S.J.1
Dolan, M.E.2
Cha, A.3
Mauceri, H.J.4
Kufe, D.W.5
Weichselbaum, R.R.6
-
3
-
-
0034776026
-
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes
-
1:CAS:528:DC%2BD3MXnsFOjtrg%3D 11603925 10.1006/jmcc.2001.1446
-
Yamamoto S, Seta K, Morisco C, Vatner SF, Sadoshima J. Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes. J Mol Cell Cardiol. 2001;33:1829-48.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 1829-1848
-
-
Yamamoto, S.1
Seta, K.2
Morisco, C.3
Vatner, S.F.4
Sadoshima, J.5
-
4
-
-
33746310059
-
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine
-
1:CAS:528:DC%2BD28XkvVymsL8%3D 16019128 10.1016/j.canlet.2005.05.037
-
Kemeny-Beke A, Aradi J, Damjanovich J, Beck Z, Facsko A, Berta A, et al. Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine. Cancer Lett. 2006;237:67-75.
-
(2006)
Cancer Lett
, vol.237
, pp. 67-75
-
-
Kemeny-Beke, A.1
Aradi, J.2
Damjanovich, J.3
Beck, Z.4
Facsko, A.5
Berta, A.6
-
5
-
-
43749124428
-
Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism
-
1:CAS:528:DC%2BD1cXjsFCgsLo%3D 18230621 10.1074/jbc.M707687200
-
Wan KF, Chan SL, Sukumaran SK, Lee MC, Yu VC. Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism. J Biol Chem. 2008;283:8423-33.
-
(2008)
J Biol Chem
, vol.283
, pp. 8423-8433
-
-
Wan, K.F.1
Chan, S.L.2
Sukumaran, S.K.3
Lee, M.C.4
Yu, V.C.5
-
6
-
-
48849113980
-
Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis
-
1:CAS:528:DC%2BD1cXpslWlsrk%3D 18555791 10.1016/j.abb.2008.05.019
-
Matkar SS, Wrischnik LA, Hellmann-Blumberg U. Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis. Arch Biochem Biophys. 2008;477:43-52.
-
(2008)
Arch Biochem Biophys
, vol.477
, pp. 43-52
-
-
Matkar, S.S.1
Wrischnik, L.A.2
Hellmann-Blumberg, U.3
-
7
-
-
67549141546
-
Different forms of cell death induced by putative BCL2 inhibitors
-
1:CAS:528:DC%2BD1MXnsV2qs74%3D 19390557 10.1038/cdd.2009.48
-
Vogler M, Weber K, Dinsdale D, Schmitz I, Schulze-Osthoff K, Dyer MJ, et al. Different forms of cell death induced by putative BCL2 inhibitors. Cell Death Differ. 2009;16:1030-9.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1030-1039
-
-
Vogler, M.1
Weber, K.2
Dinsdale, D.3
Schmitz, I.4
Schulze-Osthoff, K.5
Dyer, M.J.6
-
8
-
-
41949089291
-
Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells
-
1:CAS:528:DC%2BD1cXkvFWhu74%3D 18358694 10.1016/j.tiv.2008.02.007
-
Vrba J, Dolezel P, Vicar J, Modriansky M, Ulrichova J. Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells. Toxicol In Vitro. 2008;22:1008-17.
-
(2008)
Toxicol in Vitro
, vol.22
, pp. 1008-1017
-
-
Vrba, J.1
Dolezel, P.2
Vicar, J.3
Modriansky, M.4
Ulrichova, J.5
-
9
-
-
0141815741
-
Production of reactive oxygen species by mitochondria: Central role of complex III
-
1:CAS:528:DC%2BD3sXnt1aqtbY%3D 12840017 10.1074/jbc.M304854200
-
Chen Q, Vazquez EJ, Moghaddas S, Hoppel CL, Lesnefsky EJ. Production of reactive oxygen species by mitochondria: central role of complex III. J Biol Chem. 2003;278:36027-31.
-
(2003)
J Biol Chem
, vol.278
, pp. 36027-36031
-
-
Chen, Q.1
Vazquez, E.J.2
Moghaddas, S.3
Hoppel, C.L.4
Lesnefsky, E.J.5
-
10
-
-
79958134215
-
Mitochondrial ROS production under cellular stress: Comparison of different detection methods
-
1:CAS:528:DC%2BC3MXitFKjtbc%3D 21336935 10.1007/s00216-011-4764-2
-
Kuznetsov AV, Kehrer I, Kozlov AV, Haller M, Redl H, Hermann M, et al. Mitochondrial ROS production under cellular stress: comparison of different detection methods. Anal Bioanal Chem. 2011;400:2383-90.
-
(2011)
Anal Bioanal Chem
, vol.400
, pp. 2383-2390
-
-
Kuznetsov, A.V.1
Kehrer, I.2
Kozlov, A.V.3
Haller, M.4
Redl, H.5
Hermann, M.6
-
11
-
-
60349121674
-
N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells
-
1:CAS:528:DC%2BD1MXit1Oqurc%3D 19159629 10.1016/j.lfs.2008.12.016
-
Kumar S, Sitasawad SL. N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells. Life Sci. 2009;84:328-36.
-
(2009)
Life Sci
, vol.84
, pp. 328-336
-
-
Kumar, S.1
Sitasawad, S.L.2
-
12
-
-
82655174017
-
Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine
-
1:CAS:528:DC%2BC3MXhsVKmtrnE 21664962 10.1016/j.tiv.2011.05.028
-
Funakoshi T, Aki T, Nakayama H, Watanuki Y, Imori S, Uemura K. Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine. Toxicol In Vitro. 2011;25:1581-7.
-
(2011)
Toxicol in Vitro
, vol.25
, pp. 1581-1587
-
-
Funakoshi, T.1
Aki, T.2
Nakayama, H.3
Watanuki, Y.4
Imori, S.5
Uemura, K.6
-
13
-
-
27644558367
-
Characterization of cells with different mitochondrial membrane potential during apoptosis
-
16184612 10.1002/cyto.a.20188
-
Lugli E, Troiano L, Ferraresi R, Roat E, Prada N, Nasi M, et al. Characterization of cells with different mitochondrial membrane potential during apoptosis. Cytometry A. 2005;68:28-35.
-
(2005)
Cytometry A
, vol.68
, pp. 28-35
-
-
Lugli, E.1
Troiano, L.2
Ferraresi, R.3
Roat, E.4
Prada, N.5
Nasi, M.6
-
14
-
-
61449208877
-
Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: Role in macrophage recognition and engulfment
-
1:CAS:528:DC%2BD1MXivVartr8%3D 19106181 10.1189/jlb.0408232
-
Jitkaew S, Witasp E, Zhang S, Kagan VE, Fadeel B. Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment. J Leukoc Biol. 2009;85:427-37.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 427-437
-
-
Jitkaew, S.1
Witasp, E.2
Zhang, S.3
Kagan, V.E.4
Fadeel, B.5
-
15
-
-
58149176739
-
Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma
-
1:CAS:528:DC%2BD1cXht1KgtbrF 18927278 10.1158/1078-0432.CCR-07-5113
-
Yang R, Piperdi S, Gorlick R. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma. Clin Cancer Res. 2008;14:6396-404.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6396-6404
-
-
Yang, R.1
Piperdi, S.2
Gorlick, R.3
-
16
-
-
76749126240
-
Evidence for DpH surface component (DpHS) of proton motive force in ATP synthesis of mitochondria
-
Xiong JW, Zhu L, Jiao X, Liu SS. Evidence for DpH surface component (DpHS) of proton motive force in ATP synthesis of mitochondria. Biochim Biophys Acta. 1800;2010:213-22.
-
(1800)
Biochim Biophys Acta
, vol.2010
, pp. 213-222
-
-
Xiong, J.W.1
Zhu, L.2
Jiao, X.3
Liu, S.S.4
-
17
-
-
30444443459
-
Hydrogen peroxide induces apoptotic-like cell death in coelomocytes of Themiste petricola (Sipuncula)
-
16382165 10.2307/3593107
-
Blanco GA, Bustamante J, Garcia M, Hajos SE. Hydrogen peroxide induces apoptotic-like cell death in coelomocytes of Themiste petricola (Sipuncula). Biol Bull. 2005;209:168-83.
-
(2005)
Biol Bull
, vol.209
, pp. 168-183
-
-
Blanco, G.A.1
Bustamante, J.2
Garcia, M.3
Hajos, S.E.4
-
19
-
-
79960918410
-
Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons
-
1:CAS:528:DC%2BC3MXps1OksLk%3D 21683152 10.1016/j.biocel.2011.06.001
-
Ramiro-Cortes Y, Guemez-Gamboa A, Moran J. Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons. Int J Biochem Cell Biol. 2011;43:1373-82.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 1373-1382
-
-
Ramiro-Cortes, Y.1
Guemez-Gamboa, A.2
Moran, J.3
-
20
-
-
77649182612
-
Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells
-
1:CAS:528:DC%2BC3cXjtVShur8%3D 20138138 10.1016/j.tiv.2010.01.012
-
Slunska Z, Gelnarova E, Hammerova J, Taborska E, Slaninova I. Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells. Toxicol In Vitro. 2010;24:697-706.
-
(2010)
Toxicol in Vitro
, vol.24
, pp. 697-706
-
-
Slunska, Z.1
Gelnarova, E.2
Hammerova, J.3
Taborska, E.4
Slaninova, I.5
-
21
-
-
33750806817
-
Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft
-
1:CAS:528:DC%2BD28Xht1ersbnP 17011577 10.1016/j.jmb.2006.09.023
-
Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, et al. Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft. J Mol Biol. 2006;364:536-49.
-
(2006)
J Mol Biol
, vol.364
, pp. 536-549
-
-
Zhang, Y.H.1
Bhunia, A.2
Wan, K.F.3
Lee, M.C.4
Chan, S.L.5
Yu, V.C.6
-
22
-
-
0037082102
-
Treatment of COS-7 cells with proteasome inhibitors or gamma-interferon reduces the increase in caspase 3 activity associated with staurosporine-induced apoptosis
-
1:CAS:528:DC%2BD38XktlymtA%3D%3D 11795872 10.1006/abbi.2001.2679
-
Brophy VA, Tavare JM, Rivett AJ. Treatment of COS-7 cells with proteasome inhibitors or gamma-interferon reduces the increase in caspase 3 activity associated with staurosporine-induced apoptosis. Arch Biochem Biophys. 2002;397:199-205.
-
(2002)
Arch Biochem Biophys
, vol.397
, pp. 199-205
-
-
Brophy, V.A.1
Tavare, J.M.2
Rivett, A.J.3
-
23
-
-
0028316195
-
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C
-
1:CAS:528:DyaK2cXis1SktLc%3D 7511048
-
Jarvis WD, Turner AJ, Povirk LF, Traylor RS, Grant S. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res. 1994;54:1707-14.
-
(1994)
Cancer Res
, vol.54
, pp. 1707-1714
-
-
Jarvis, W.D.1
Turner, A.J.2
Povirk, L.F.3
Traylor, R.S.4
Grant, S.5
-
24
-
-
0037424245
-
Mitochondrial complex i inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
-
1:CAS:528:DC%2BD3sXhsF2htrg%3D 12496265 10.1074/jbc.M210432200
-
Li N, Ragheb K, Lawler G, Sturgis J, Rajwa B, Melendez JA, et al. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem. 2003;278:8516-25.
-
(2003)
J Biol Chem
, vol.278
, pp. 8516-8525
-
-
Li, N.1
Ragheb, K.2
Lawler, G.3
Sturgis, J.4
Rajwa, B.5
Melendez, J.A.6
-
25
-
-
38349043984
-
Mitochondrial electron-transport-chain inhibitors of complexes i and II induce autophagic cell death mediated by reactive oxygen species
-
1:CAS:528:DC%2BD1cXmtFeiug%3D%3D 18032788 10.1242/jcs.011163
-
Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci. 2007;120:4155-66.
-
(2007)
J Cell Sci
, vol.120
, pp. 4155-4166
-
-
Chen, Y.1
McMillan-Ward, E.2
Kong, J.3
Israels, S.J.4
Gibson, S.B.5
-
26
-
-
0242684216
-
Effect of chelerythrine on mitochondrial energy coupling
-
1:CAS:528:DyaE38Xkt12kt7o%3D 11946508 10.1016/0014-5793(72)80135-2
-
Vallejos RH, Rizzotto MG. Effect of chelerythrine on mitochondrial energy coupling. FEBS Lett. 1972;21:195-8.
-
(1972)
FEBS Lett
, vol.21
, pp. 195-198
-
-
Vallejos, R.H.1
Rizzotto, M.G.2
-
27
-
-
84863738048
-
Molecular mechanisms of superoxide production by the mitochondrial respiratory chain
-
22729857 10.1007/978-1-4614-3573-0-6
-
Drose S, Brandt U. Molecular mechanisms of superoxide production by the mitochondrial respiratory chain. Adv Exp Med Biol. 2012;748:145-69.
-
(2012)
Adv Exp Med Biol
, vol.748
, pp. 145-169
-
-
Drose, S.1
Brandt, U.2
-
28
-
-
0242654822
-
Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids
-
1:CAS:528:DC%2BD3sXovVWrsLw%3D 14615066 10.1016/j.toxlet.2003.09.007
-
Barreto MC, Pinto RE, Arrabaca JD, Pavao ML. Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. Toxicol Lett. 2003;146:37-47.
-
(2003)
Toxicol Lett
, vol.146
, pp. 37-47
-
-
Barreto, M.C.1
Pinto, R.E.2
Arrabaca, J.D.3
Pavao, M.L.4
-
29
-
-
33746102508
-
The ROS production induced by a reverse-electron flux at respiratory chain complex1 is hampered by metformin
-
1:CAS:528:DC%2BD28XmvFeisbc%3D 16732470 10.1007/s10863-006-9003-8
-
Batandier C, Guigas B, Detaille D, El-Mir M, Fontaine E, Rigoulet M, et al. The ROS production induced by a reverse-electron flux at respiratory chain complex1 is hampered by metformin. J Bioenerg Biomembr. 2006;38:33-42.
-
(2006)
J Bioenerg Biomembr
, vol.38
, pp. 33-42
-
-
Batandier, C.1
Guigas, B.2
Detaille, D.3
El-Mir, M.4
Fontaine, E.5
Rigoulet, M.6
-
31
-
-
0032504574
-
Mitochondrial control of apoptosis: The role of cytochrome c
-
1:CAS:528:DyaK1cXltFWksLk%3D 9714780 10.1016/S0005-2728(98)00109-1
-
Cai J, Yang J, Jones DP. Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta. 1998;1366:139-49.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 139-149
-
-
Cai, J.1
Yang, J.2
Jones, D.P.3
-
32
-
-
36048995907
-
Site-specific binding of chelerythrine to single cytosine and thymine bulges in DNA hairpins
-
10.1093/nass/nrl098
-
Bai LP, Zhao ZZ, Cai Z, Jiang ZH. Site-specific binding of chelerythrine to single cytosine and thymine bulges in DNA hairpins. Nucleic Acids Symp Ser (Oxf). 2006;50:197-208.
-
(2006)
Nucleic Acids Symp ser (Oxf)
, vol.50
, pp. 197-208
-
-
Bai, L.P.1
Zhao, Z.Z.2
Cai, Z.3
Jiang, Z.H.4
-
33
-
-
39549118352
-
Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells
-
1:CAS:528:DC%2BD1cXivVygs7g%3D 18029203 10.1016/j.cellbi.2007.09.004
-
Kaminskyy V, Lin KW, Filyak Y, Stoika R. Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells. Cell Biol Int. 2008;32:271-7.
-
(2008)
Cell Biol Int
, vol.32
, pp. 271-277
-
-
Kaminskyy, V.1
Lin, K.W.2
Filyak, Y.3
Stoika, R.4
-
34
-
-
40849146903
-
A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids
-
1:CAS:528:DC%2BD1cXjs1Whsbk%3D 18325696 10.1016/j.toxlet.2008.01.009
-
Kaminskyy V, Kulachkovskyy O, Stoika R. A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids. Toxicol Lett. 2008;177:168-81.
-
(2008)
Toxicol Lett
, vol.177
, pp. 168-181
-
-
Kaminskyy, V.1
Kulachkovskyy, O.2
Stoika, R.3
-
35
-
-
0032211437
-
Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical
-
1:CAS:528:DyaK1cXnsVKiu7o%3D 9823548 10.1016/S0891-5849(98)00163-4
-
Benov L, Sztejnberg L, Fridovich I. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic Biol Med. 1998;25:826-31.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 826-831
-
-
Benov, L.1
Sztejnberg, L.2
Fridovich, I.3
-
36
-
-
84870409504
-
Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand
-
22526333 10.3727/096368912X639035
-
Rodrigues M, Turner O, Stolz D, Griffith LG, Wells A. Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand. Cell Transplant. 2012;21:2171-87.
-
(2012)
Cell Transplant
, vol.21
, pp. 2171-2187
-
-
Rodrigues, M.1
Turner, O.2
Stolz, D.3
Griffith, L.G.4
Wells, A.5
-
37
-
-
84877771859
-
Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis
-
10.1016/j.biochi.2013.01.001 23353111
-
Vallejo CG, Cruz-Bermudez A, Clemente P, Hernandez-Sierra R, Garesse R, Quintanilla M. Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis. Biochimie. 2013. doi: 10.1016/j.biochi.2013.01.001.
-
(2013)
Biochimie
-
-
Vallejo, C.G.1
Cruz-Bermudez, A.2
Clemente, P.3
Hernandez-Sierra, R.4
Garesse, R.5
Quintanilla, M.6
|