Interferon-γ impairs proliferation of hematopoietic stem cells in mice

Blood

Volumn 121, Issue 18, 2013, Pages 3578-3585

  De Bruin, Alexander M ^a   Demirel, Özlem ^b   Hooibrink, Berend ^a   Brandts, Christian H ^b   Nolte, Martijn A ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b GOETHE UNIVERSITY   (Germany)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD150 ANTIGEN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1C; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; THROMBOPOIETIN; GAMMA INTERFERON RECEPTOR; INTERFERON RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RESPONSE; FLOW CYTOMETRY; GENE EXPRESSION; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; WILD TYPE; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; GENETICS; HEMATOPOIESIS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; INFLAMMATION; INTERFERON-GAMMA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; THROMBOPOIETIN; VIRUS DISEASES;

MLCS; MLOWN;

EID: 84879722412     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-05-432906     Document Type: Article

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