Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice

Matrix Biology

Volumn 34, Issue , 2014, Pages 13-21

  Rubel, Diana ^a   Frese, Jenny ^a   Martin, Maria ^a   Leibnitz, Alexander ^a   Girgert, Rainer ^a   Miosge, Nicolai ^a   Eckes, Beate ^b   Müller, Gerhard Anton ^a   Gross, Oliver ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Alport syndrome; Collagen receptors; Integrins; Renal fibrosis; Type IV collagen

Indexed keywords

COLLAGEN RECEPTOR; DISCOIDIN RECEPTOR; LECTIN RECEPTOR; PROTEIN TYROSINE KINASE; VERY LATE ACTIVATION ANTIGEN 2;

ANIMAL; BIOSYNTHESIS; EXTRACELLULAR MATRIX; FIBROSIS; GENETICS; GLOMERULUS; GLOMERULUS BASEMENT MEMBRANE; GROWTH, DEVELOPMENT AND AGING; HUMAN; KIDNEY; KNOCKOUT MOUSE; METABOLISM; MOUSE; NEPHRITIS; PATHOLOGY;

ANIMALS; EXTRACELLULAR MATRIX; FIBROSIS; GLOMERULAR BASEMENT MEMBRANE; HUMANS; INTEGRIN ALPHA2BETA1; KIDNEY; KIDNEY GLOMERULUS; MICE; MICE, KNOCKOUT; NEPHRITIS, HEREDITARY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, COLLAGEN; RECEPTORS, MITOGEN;

EID: 84893770509     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2014.01.006     Document Type: Article

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