메뉴 건너뛰기




Volumn 172, Issue 3, 2008, Pages 761-773

Integrin α1β1 regulates matrix metalloproteinases via p38 mitogen-activated protein kinase in mesangial cells: Implications for alport syndrome

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; TANOMASTAT; VERY LATE ACTIVATION ANTIGEN 1; AUTOANTIGEN; COLLAGEN TYPE 4; ORGANIC COMPOUND; TISSUE INHIBITOR OF METALLOPROTEINASE; TYPE IV COLLAGEN ALPHA3 CHAIN;

EID: 40449098083     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.070473     Document Type: Article
Times cited : (33)

References (54)
  • 1
    • 0032823921 scopus 로고    scopus 로고
    • Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes
    • CE Kashtan Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes Medicine 78 1999 338 360
    • (1999) Medicine , vol.78 , pp. 338-360
    • Kashtan, CE1
  • 2
    • 0035993264 scopus 로고    scopus 로고
    • Animal models of Alport syndrome
    • CE Kashtan Animal models of Alport syndrome Nephrol Dial Transplant 17 2002 1359 1361
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1359-1361
    • Kashtan, CE1
  • 3
    • 0033623532 scopus 로고    scopus 로고
    • Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy
    • D Cosgrove K Rodgers D Meehan C Miller K Bovard A Gilroy H Gardner V Kotelianski P Gotwals A Amatucci R Kalluri Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy Am J Pathol 157 2000 1649 1659
    • (2000) Am J Pathol , vol.157 , pp. 1649-1659
    • Cosgrove, D1    Rodgers, K2    Meehan, D3    Miller, C4    Bovard, K5    Gilroy, A6    Gardner, H7    Kotelianski, V8    Gotwals, P9    Amatucci, A10    Kalluri, R11
  • 4
    • 0025076791 scopus 로고
    • The α1-α6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron
    • 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron J Cell Biol 111 1990 1245 1254
    • (1990) J Cell Biol , vol.111 , pp. 1245-1254
    • Korhonen, M1    Ylänne, J2    Laitinen, L3    Virtanen, I4
  • 5
    • 0028945919 scopus 로고
    • Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2
    • DL Mendrick DM Kelly SS duMont DJ Sandstrom Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2 Lab Invest 72 1995 367 375
    • (1995) Lab Invest , vol.72 , pp. 367-375
    • Mendrick, DL1    Kelly, DM2    duMont, SS3    Sandstrom, DJ4
  • 6
  • 7
    • 0032588651 scopus 로고    scopus 로고
    • Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB
    • S Kagami S Kondo K Loster W Reutter T Kuhara K Yasutomo Y Kuroda Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB J Am Soc Nephrol 10 1999 779 789
    • (1999) J Am Soc Nephrol , vol.10 , pp. 779-789
    • Kagami, S1    Kondo, S2    Loster, K3    Reutter, W4    Kuhara, T5    Yasutomo, K6    Kuroda, Y7
  • 9
    • 0035881282 scopus 로고    scopus 로고
    • Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells
    • S Kagami M Urushihara S Kondo K Loster W Reutter T Tamaki M Yoshizumi Y Kuroda Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells Exp Cell Res 268 2001 274 283
    • (2001) Exp Cell Res , vol.268 , pp. 274-283
    • Kagami, S1    Urushihara, M2    Kondo, S3    Loster, K4    Reutter, W5    Tamaki, T6    Yoshizumi, M7    Kuroda, Y8
  • 10
    • 0033035808 scopus 로고    scopus 로고
    • Absence of integrin α1β1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis
    • H Gardner A Broberg A Pozzi M Laato J Heino Absence of integrin α1β1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis J Cell Sci 112 1999 263 272
    • (1999) J Cell Sci , vol.112 , pp. 263-272
    • Gardner, H1    Broberg, A2    Pozzi, A3    Laato, M4    Heino, J5
  • 11
    • 0034007381 scopus 로고    scopus 로고
    • Elevated matrix metalloproteinase and angiostatin levels in integrin a1 knockout mice cause reduced tumor vascularization
    • A Pozzi PE Moberg LA Miles S Wagner P Soloway HA Gardner Elevated matrix metalloproteinase and angiostatin levels in integrin a1 knockout mice cause reduced tumor vascularization Proc Natl Acad Sci USA 97 2000 2202 2207
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2202-2207
    • Pozzi, A1    Moberg, PE2    Miles, LA3    Wagner, S4    Soloway, P5    Gardner, HA6
  • 12
    • 0037050259 scopus 로고    scopus 로고
    • Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis
    • A Pozzi WF LeVine HA Gardner Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis Oncogene 21 2002 272 281
    • (2002) Oncogene , vol.21 , pp. 272-281
    • Pozzi, A1    LeVine, WF2    Gardner, HA3
  • 13
    • 0036020910 scopus 로고    scopus 로고
    • Glomerular distribution and gelatinolytic activity of matrix metalloproteinases in human glomerulonephritis
    • M Urushihara S Kagami T Kuhara T Tamaki Y Kuroda Glomerular distribution and gelatinolytic activity of matrix metalloproteinases in human glomerulonephritis Nephrol Dial Transplant 17 2002 1189 1196
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1189-1196
    • Urushihara, M1    Kagami, S2    Kuhara, T3    Tamaki, T4    Kuroda, Y5
  • 14
    • 0034669989 scopus 로고    scopus 로고
    • Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways
    • W Eberhardt A Huwiler KF Beck S Walpen J Pfeilschifter Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways J Immunol 165 2000 5788 5797
    • (2000) J Immunol , vol.165 , pp. 5788-5797
    • Eberhardt, W1    Huwiler, A2    Beck, KF3    Walpen, S4    Pfeilschifter, J5
  • 15
    • 4444313481 scopus 로고    scopus 로고
    • Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line
    • JE Ayala JN Boustead SC Chapman CA Svitek JK Oeser RB Robey RM O'Brien Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line J Mol Endocrinol 33 2004 263 280
    • (2004) J Mol Endocrinol , vol.33 , pp. 263-280
    • Ayala, JE1    Boustead, JN2    Chapman, SC3    Svitek, CA4    Oeser, JK5    Robey, RB6    O'Brien, RM7
  • 17
    • 0029894277 scopus 로고    scopus 로고
    • Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion
    • H Gardner J Kreidberg V Kotelianski R Jaenisch Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion Dev Biol 175 1996 301 313
    • (1996) Dev Biol , vol.175 , pp. 301-313
    • Gardner, H1    Kreidberg, J2    Kotelianski, V3    Jaenisch, R4
  • 19
    • 0018185366 scopus 로고
    • Isolation and characterization of rat glomerular epithelial cells in vitro
    • JI Kreisberg RL Hoover MJ Karnovsky Isolation and characterization of rat glomerular epithelial cells in vitro Kidney Int 14 1978 21 30
    • (1978) Kidney Int , vol.14 , pp. 21-30
    • Kreisberg, JI1    Hoover, RL2    Karnovsky, MJ3
  • 21
    • 0016769615 scopus 로고
    • D-valine as a selective agent for normal human and rodent epithelial cells in culture
    • SF Gilbert BR Migeon D-valine as a selective agent for normal human and rodent epithelial cells in culture Cell 5 1975 11 17
    • (1975) Cell , vol.5 , pp. 11-17
    • Gilbert, SF1    Migeon, BR2
  • 22
    • 0034960672 scopus 로고    scopus 로고
    • Mesangial cell cultures
    • P Menè Mesangial cell cultures J Nephrol 14 2000 198 203
    • (2000) J Nephrol , vol.14 , pp. 198-203
    • Menè, P1
  • 23
    • 17844408713 scopus 로고    scopus 로고
    • Matrix metalloproteinase dysregulation in the stria vascularis of Alport mice: implications for capillary basement membrane pathology
    • MA Gratton VH Rao D Cosgrove Matrix metalloproteinase dysregulation in the stria vascularis of Alport mice: implications for capillary basement membrane pathology Am J Pathol 166 2005 1465 1474
    • (2005) Am J Pathol , vol.166 , pp. 1465-1474
    • Gratton, MA1    Rao, VH2    Cosgrove, D3
  • 26
  • 27
    • 1242294522 scopus 로고    scopus 로고
    • PDGR-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells
    • S Kagami M Urushihara A Kitamura S Kondo T Hisayama M Kitamura K Loster W Reutter Y Kuroda PDGR-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells J Cell Physiol 198 2004 470 478
    • (2004) J Cell Physiol , vol.198 , pp. 470-478
    • Kagami, S1    Urushihara, M2    Kitamura, A3    Kondo, S4    Hisayama, T5    Kitamura, M6    Loster, K7    Reutter, W8    Kuroda, Y9
  • 28
    • 0036095081 scopus 로고    scopus 로고
    • Autocrine activation of the IGF-I signaling pathway in mesangial cells isolated from diabetic NOD mice
    • I Tack SJ Elliot M Potier A Rivera GE Striker LJ Striker Autocrine activation of the IGF-I signaling pathway in mesangial cells isolated from diabetic NOD mice Diabetes 51 2002 182 188
    • (2002) Diabetes , vol.51 , pp. 182-188
    • Tack, I1    Elliot, SJ2    Potier, M3    Rivera, A4    Striker, GE5    Striker, LJ6
  • 30
    • 0035819527 scopus 로고    scopus 로고
    • Development of matrix metalloproteinase inhibitors in cancer therapy
    • M Hidalgo SG Eckhardt Development of matrix metalloproteinase inhibitors in cancer therapy J Natl Cancer Inst 93 2001 179 193
    • (2001) J Natl Cancer Inst , vol.93 , pp. 179-193
    • Hidalgo, M1    Eckhardt, SG2
  • 31
    • 21544434331 scopus 로고    scopus 로고
    • p38 MAP kinase inhibitors: many are made, but few are chosen
    • C Dominguez DA Powers N Tamayo p38 MAP kinase inhibitors: many are made, but few are chosen Curr Opin Drug Discov Dev 8 2005 421 430
    • (2005) Curr Opin Drug Discov Dev , vol.8 , pp. 421-430
    • Dominguez, C1    Powers, DA2    Tamayo, N3
  • 33
    • 85120111226 scopus 로고    scopus 로고
    • Murphy G, Willenbrock F, Crabbe T, O'Shea M, Ward R., Atkinson S, O'Conell J, Docherty A: Regulation of matrix metalloproteinase activity. Proc Natl Acad Sci USA 732:31–41
  • 34
    • 0033817966 scopus 로고    scopus 로고
    • An MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist
    • E Roeb I Behrmann Grötzinger B Breuer An MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist FASEB J 14 2000 1671 1673
    • (2000) FASEB J , vol.14 , pp. 1671-1673
    • Roeb, E1    Behrmann, I2    Grötzinger3    Breuer, B4
  • 35
    • 25444445358 scopus 로고    scopus 로고
    • Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-α-converting enzyme
    • S Wei M Kashiwagi S Kota Z Xie H Nagase K Brew Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-α-converting enzyme J Biol Chem 280 2005 32877 32882
    • (2005) J Biol Chem , vol.280 , pp. 32877-32882
    • Wei, S1    Kashiwagi, M2    Kota, S3    Xie, Z4    Nagase, H5    Brew, K6
  • 36
    • 0033901350 scopus 로고    scopus 로고
    • Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome
    • KL Andrews T Betsuyaku S Rogers JM Shipley RM Senior JH Miner Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome Am J Pathol 157 2000 303 311
    • (2000) Am J Pathol , vol.157 , pp. 303-311
    • Andrews, KL1    Betsuyaku, T2    Rogers, S3    Shipley, JM4    Senior, RM5    Miner, JH6
  • 38
    • 33745841589 scopus 로고    scopus 로고
    • Loss of alpha3/alpha4(IV) collagen from glomerular basement membrane induces a strain-dependent isoform switch to alpha5/alpha6(IV) collagen associated with longer renal survival in Col4a3−/− Alport mice
    • JS Kang XP Wang JH Miner R Morello Y Sado DR Abrahamson DB Baorza Loss of alpha3/alpha4(IV) collagen from glomerular basement membrane induces a strain-dependent isoform switch to alpha5/alpha6(IV) collagen associated with longer renal survival in Col4a3−/− Alport mice J Am Soc Nephrol 17 2006 1962 1969
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1962-1969
    • Kang, JS1    Wang, XP2    Miner, JH3    Morello, R4    Sado, Y5    Abrahamson, DR6    Baorza, DB7
  • 39
    • 33947647479 scopus 로고    scopus 로고
    • Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis
    • D Cosgrove R Kalluri J Miner Y Segal D-B Borza Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis Kidney Int 71 2007 615 618
    • (2007) Kidney Int , vol.71 , pp. 615-618
    • Cosgrove, D1    Kalluri, R2    Miner, J3    Segal, Y4    Borza, D-B5
  • 40
    • 0036174534 scopus 로고    scopus 로고
    • Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome
    • KL Andrews JL Mudd JH Miner Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome Am J Pathol 160 2002 721 730
    • (2002) Am J Pathol , vol.160 , pp. 721-730
    • Andrews, KL1    Mudd, JL2    Miner, JH3
  • 42
    • 0036423702 scopus 로고    scopus 로고
    • Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells
    • Y Uchiyama-Tanaka H Matsubara Y Mori A Kosaki N Kishimoto K Amano S Higashiyama T Iwasaka Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells Kidney Int 62 2002 799 808
    • (2002) Kidney Int , vol.62 , pp. 799-808
    • Uchiyama-Tanaka, Y1    Matsubara, H2    Mori, Y3    Kosaki, A4    Kishimoto, N5    Amano, K6    Higashiyama, S7    Iwasaka, T8
  • 43
    • 4143092587 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses
    • C Xin S Ren B Kleuser S Shabahang W Eberhardt H Radeke M Schager-Korting J Pfeilschifter A Huwiler Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses J Biol Chem 279 2004 35255 35262
    • (2004) J Biol Chem , vol.279 , pp. 35255-35262
    • Xin, C1    Ren, S2    Kleuser, B3    Shabahang, S4    Eberhardt, W5    Radeke, H6    Schager-Korting, M7    Pfeilschifter, J8    Huwiler, A9
  • 44
    • 26444475881 scopus 로고    scopus 로고
    • Extracellular matrix human alpha 1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated through alpha 1 beta 1 integrin
    • A Sudhakar P Nyberg G Venkateshwar AP Keshamouni JL Mannam H Sugimoto DE Cosgrove R Kalluri Extracellular matrix human alpha 1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated through alpha 1 beta 1 integrin J Clin Invest 115 2005 2801 2810
    • (2005) J Clin Invest , vol.115 , pp. 2801-2810
    • Sudhakar, A1    Nyberg, P2    Venkateshwar, G3    Keshamouni, AP4    Mannam, JL5    Sugimoto, H6    Cosgrove, DE7    Kalluri, R8
  • 45
    • 0036950810 scopus 로고    scopus 로고
    • Collagen-binding integrin alpha 1 beta 1 regulates intestinal inflammation in experimental colitis
    • CF Krieglstein WH Cerwinka AG Sprague Collagen-binding integrin alpha 1 beta 1 regulates intestinal inflammation in experimental colitis J Clin Invest 110 2002 773 782
    • (2002) J Clin Invest , vol.110 , pp. 773-782
    • Krieglstein, CF1    Cerwinka, WH2    Sprague, AG3
  • 47
    • 0036790372 scopus 로고    scopus 로고
    • Treatment with an antibody to α1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis
    • HT Cook SB Khan A Allen G Bhangal J Smith RR Lobb CD Pusey Treatment with an antibody to α1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis Am J Pathol 161 2002 1265 1272
    • (2002) Am J Pathol , vol.161 , pp. 1265-1272
    • Cook, HT1    Khan, SB2    Allen, A3    Bhangal, G4    Smith, J5    Lobb, RR6    Pusey, CD7
  • 52
    • 0035720014 scopus 로고    scopus 로고
    • Alterations of vitronectin and its receptor alpha(v) integrin in the rat renal glomerular wall during diabetes
    • S Yoon D Ginras M Bendayan Alterations of vitronectin and its receptor alpha(v) integrin in the rat renal glomerular wall during diabetes Am J Kidney Dis 38 2001 1298 1306
    • (2001) Am J Kidney Dis , vol.38 , pp. 1298-1306
    • Yoon, S1    Ginras, D2    Bendayan, M3
  • 53
    • 0030601935 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-beta) stimulates the expression of beta1 integrins and adhesion by rat mesangial cells
    • S Kagami T Kuhara K Yasutomo K Okada K Löster W Reutter Y Kuroda Transforming growth factor-beta (TGF-beta) stimulates the expression of beta1 integrins and adhesion by rat mesangial cells Exp Cell Res 25 1996 1 6
    • (1996) Exp Cell Res , vol.25 , pp. 1-6
    • Kagami, S1    Kuhara, T2    Yasutomo, K3    Okada, K4    Löster, K5    Reutter, W6    Kuroda, Y7
  • 54
    • 0035313462 scopus 로고    scopus 로고
    • Cross-talk between α4β1/α5β1 and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways
    • R Kapur R Cooper L Zhang DA Williams Cross-talk between α4β1/α5β1 and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways Blood 97 2001 1975 1981
    • (2001) Blood , vol.97 , pp. 1975-1981
    • Kapur, R1    Cooper, R2    Zhang, L3    Williams, DA4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.