A perylene derivative regulates HIF-1α and Stat3 signaling pathways

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 4, 2014, Pages 1496-1505

  Chen, Han ^a,b   Guan, Yongli ^a   Yuan, Gu ^b   Zhang, Qiang ^b   Jing, Naijie ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b PEKING UNIVERSITY   (China)

Author keywords

Breast cancer therapy; HIF 1 : hypoxia inducible factor 1 ; Pancreatic cancer therapy; Stat3: the signal transducer and activator of transcription 3; TEL03: a dual inhibitor of HIF 1 and Stat3

Indexed keywords

BREAST CANCER THERAPY; HIF-1Α: HYPOXIA-INDUCIBLE FACTOR-1Α; PANCREATIC CANCER THERAPY; STAT3: THE SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; TEL03: A DUAL INHIBITOR OF HIF-1Α AND STAT3;

ANIMALS; APOPTOSIS; BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMIDES; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR DOCKING SIMULATION; PERYLENE; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84893747966     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.10.018     Document Type: Article

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