A new telomerase inhibitor and apoptosis-inducing agent in leukemia: Perylene derivative G-quadruplex ligand Tel03

Drug Development Research

Volumn 69, Issue 5, 2008, Pages 235-241

  Chu, Bin ^a   Yuan, Gu ^b   Zhou, Jiang ^b   Ou, Yuan ^a   Zhu, Ping ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Apoptosis; G quadruplex; Leukemia; Mass spectrometry; Telomerase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTILEUKEMIC AGENT; MESSENGER RNA; MYC PROTEIN; N,N' BIS[2 (DIMETHYLAMINO)ETHYL] 3,4,9,10 PERYLENETETRACARBOXYLIC ACID DIIMIDE; PERYLENE; PROTEIN BAX; PROTEIN BCL 2; TEL 03; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN K 562; CONTROLLED STUDY; DOWN REGULATION; DRUG DNA BINDING; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; MOLECULAR RECOGNITION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; WESTERN BLOTTING;

EID: 54549092618     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20248     Document Type: Article

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