Sodium iron EDTA and ascorbic acid, but not polyphenol oxidase treatment, counteract the strong inhibitory effect of polyphenols from brown sorghum on the absorption of fortification iron in young women

British Journal of Nutrition

Volumn 111, Issue 3, 2014, Pages 481-489

  Cercamondi, Colin I ^a   Egli, Ines M ^a   Zeder, Christophe ^a   Hurrell, Richard F ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Iron absorption; Iron fortification; Polyphenols; Sorghum

Indexed keywords

ADULT; ANEMIA, IRON-DEFICIENCY; ASCORBIC ACID; CEREALS; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; EDETIC ACID; FEMALE; FERRIC COMPOUNDS; FOOD, FORTIFIED; GASTROINTESTINAL AGENTS; HEMATINICS; HUMANS; INTESTINAL ABSORPTION; IRON CHELATING AGENTS; IRON, DIETARY; NUTRITIVE VALUE; PIGMENTS, BIOLOGICAL; POLYPHENOLS; SEEDS; SORGHUM; SWITZERLAND; YOUNG ADULT;

ASCORBIC ACID; C REACTIVE PROTEIN; EDETATE IRON SODIUM; EDETATE SODIUM; FERRITIN; FERROUS SULFATE; HEMOGLOBIN; IRON; IRON 54; IRON 57; IRON 58; ISOTOPE; LACCASE; PHYTATE; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOAVAILABILITY; BLOOD SAMPLING; BROWN SORGHUM; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG TARGETING; ERYTHROCYTE LEVEL; FEMALE; FERRITIN BLOOD LEVEL; FLOUR; FOOD INTAKE; HEMOGLOBIN BLOOD LEVEL; HUMAN; IRON ABSORPTION; IRON DEFICIENCY ANEMIA; ISOTOPE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SORGHUM; VARIETAS; WHITE SORGHUM; WOMEN'S HEALTH;

EID: 84893687319     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114513002705     Document Type: Article

References (52)

1. McLean E, Cogswell M, Egli I, et al. (2009) Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005. Public Health Nutr 12, 444-454.
2. Zimmermann MB & Hurrell RF (2007) Nutritional iron deficiency. Lancet 370, 511-520.
3. Aikawa R, Ngyen CK, Sasaki S, et al. (2006) Risk factors for iron-deficiency anaemia among pregnant women living in rural Vietnam. Public Health Nutr 9, 443-448.
4. Zimmermann MB, Chaouki N & Hurrell RF (2005) Iron deficiency due to consumption of a habitual diet low in bioavailable iron: a longitudinal cohort study in Moroccan children. Am J Clin Nutr 81, 115-121.
5. Rooney LW & Waniska RD (2000) Sorghum food and industrial utilization. In Origin, History, Technology, and Production, pp. 689-729 [CW Smith and RA Frederiksen, editors]. New York, NY: John Wiley and Sons.
6. Godwin ID & Gray SJ (2000) Overcoming productivity and quality constraints in sorghum: the role for genetic engineering. In Transgenic Cereals, pp. 153-177 [L O'Brien and RJ Henry, editors]. St. Paul, MN: American Association of Cereal Chemists.
7. Dicko MH, Hilhorst R, Gruppen H, et al. (2002) Comparison of content in phenolic compounds, polyphenol oxidase, and peroxidase in grains of fifty sorghum varieties from Burkina Faso. J Agric Food Chem 50, 3780-3788.
8. Anglani C (1998) Sorghum for human food-a review. Plant Food Hum Nutr 52, 85-95.
9. Kayode APP, Adegbidi A, Hounhouigan JD, et al. (2005) Quality of farmers' varieties of sorghum and derived foods as perceived by consumers in Benin. Ecol Food Nutr 44, 271-294.
10. Badi S, Pedersen B, Monowar L, et al. (1990) The nutritive value of new and traditional sorghum and millet foods from Sudan. Plant Food Hum Nutr 40, 5-19.
11. Onofiok NO & Nnanyelugo DO (1998) Weaning foods in West Africa: nutritional problems and possible solutions. Food Nutr Bull 19, 27-33(7).
12. Igbedioh SO, Ogbeni AO & Adole GM (1996) Infant weaning practices of some Tiv women resident in Makurdi, Nigeria. Nutr Health 11, 13-28.
13. Kayode AP, Nout MJ, Bakker EJ, et al. (2006) Evaluation of the simultaneous effects of processing parameters on the iron and zinc solubility of infant sorghum porridge by response surface methodology. J Agric Food Chem 54, 4253-4259.
14. Mitchikpe ECS, Dossa RAM, Ategbo EAD, et al. (2008) The supply of bioavailable iron and zinc may be affected by phytate in Beninese children. J Food Compos Anal 21, 17-25.
15. Kayode AP, Linnemann AR, Hounhouigan JD, et al. (2006) Genetic and environmental impact on iron, zinc, and phytate in food sorghum grown in Benin. J Agric Food Chem 54, 256-262.
16. Makokha AO, Oniang'o RK, Njoroge SM, et al. (2002) Effect of traditional fermentation and malting on phytic acid and mineral availability from sorghum (Sorghum bicolor) and finger millet (Eleusine coracana) grain varieties grown in Kenya. Food Nutr Bull 23, 241-245.
17. Towo EE, Svanberg U & Ndossi GD (2003) Effect of grain pre-treatment on different extractable phenolic groups in cereals and legumes commonly consumed in Tanzania. J Sci Food Agric 83, 980-986.
18. Hallberg L, Rossander L & Skanberg AB (1987) Phytates and the inhibitory effect of bran on iron absorption in man. Am J Clin Nutr 45, 988-996.
19. Hurrell RF, Reddy M & Cook JD (1999) Inhibition of nonhaem iron absorption in man by polyphenolic-containing beverages. Br J Nutr 81, 289-295.
20. Brune M, Rossander L & Hallberg L (1989) Iron absorption and phenolic compounds: importance of different phenolic structures. Eur J Clin Nutr 43, 547-557.
21. Tuntipopipat S, Judprasong K, Zeder C, et al. (2006) Chili, but not turmeric, inhibits iron absorption in young women from an iron-fortified composite meal. J Nutr 136, 2970-2974.
22. Hahn DH & Rooney LW (1986) Effect of genotype on tannins and phenols of sorghum. Cereal Chem 63, 4-8.
23. Dykes L & Rooney LW (2006) Sorghum and millet phenols and antioxidants. J Cereal Sci 44, 236-251.
24. Dykes L, Rooney LW, Waniska RD, et al. (2005) Phenolic compounds and antioxidant activity of sorghum grains of varying genotypes. J Agric Food Chem 53, 6813-6818.
25. Hurrell RF, Reddy MB, Juillerat MA, et al. (2003) Degradation of phytic acid in cereal porridges improves iron absorption by human subjects. Am J Clin Nutr 77, 1213-1219.
26. Hurrell R, Ranum P, de Pee S, et al. (2010) Revised recommendations for iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs. Food Nutr Bull 31, S7-S21.
27. Hurrell RF, Reddy MB, Burri J, et al. (2000) An evaluation of EDTA compounds for iron fortification of cereal-based foods. Br J Nutr 84, 903-910.
28. Hallberg L, Brune M & Rossander L (1989) Iron-absorption in man-ascorbic-acid and dose-dependent inhibition by phytate. Am J Clin Nutr 49, 140-144.
29. Walczyk T, Davidsson L, Zavaleta N, et al. (1997) Stable isotope labels as a tool to determine the iron absorption by Peruvian school children from a breakfast meal. Fresen J Anal Chem 359, 445-449.
30. Makower RU (1970) Extraction and determination of phytic acid in beans (Phaseolus vulgaris). Cereal Chem 47, 288-296.
31. Van Veldhoven PP & Mannaerts GP (1987) Inorganic and organic phosphate measurements in the nanomolar range. Anal Biochem 161, 45-48.
32. Singleton VL & Rossi JA (1965) Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Viticult 16, 144-158.
33. Luten J, Crews H, Flynn A, et al. (1996) Interlaboratory trial on the determination of the in vitro iron dialysability from food. J Sci Food Agric 72, 415-424.
34. World Health Organization (2001) Iron Deficiency Anemia: Assessment, Prevention and Control. Geneva: WHO.
35. Hotz K, Krayenbuehl PA & Walczyk T (2012) Mobilization of storage iron is reflected in the iron isotopic composition of blood in humans. J Biol Inorg Chem 17, 301-309.
36. Brown E, Hopper J Jr, Hodges JL Jr, et al. (1962) Red cell, plasma, and blood volume in the healthy women measured by radiochromium cell-labeling and hematocrit. J Clin Invest 41, 2182-2190.
37. Turnlund JR, Keyes WR & Peiffer GL (1993) Isotope ratios of molybdenum determined by thermal ionization massspectrometry for stable-isotope studies of molybdenum metabolism in humans. Anal Chem 65, 1717-1722.
38. Barrett JF, Whittaker PG, Williams JG, et al. (1992) Absorption of non-haem iron in normal women measured by the incorporation of two stable isotopes into erythrocytes. Clin Sci (Lond) 83, 213-219.
39. Petry N, Egli I, Gahutu JB, et al. (2012) Stable iron isotope studies in Rwandese women indicate that the common bean has limited potential as a vehicle for iron biofortification. J Nutr 142, 492-497.
40. Petry N, Egli I, Zeder C, et al. (2010) Polyphenols and phytic acid contribute to the low iron bioavailability from common beans in young women. J Nutr 140, 1977-1982.
41. Gillooly M, Bothwell TH, Charlton RW, et al. (1984) Factors affecting the absorption of iron from cereals. Br J Nutr 51, 37-46.
42. Radhakrishnan MR & Sivaprasad J (1980) Tannin content of sorghum varieties and their role in iron bioavailability. J Agric Food Chem 28, 55-57.
43. Awika JM, Dykes L, Gu L, et al. (2003) Processing of sorghum (Sorghum bicolor) and sorghum products alters procyanidin oligomer and polymer distribution and content. J Agric Food Chem 51, 5516-5521.
44. Kayode APP, Linnemann AR, Nout MJR, et al. (2007) Impact of sorghum processing on phytate, phenolic compounds and in vitro solubility of iron and zinc in thick porridges. J Sci Food Agric 87, 832-838.
45. Macphail AP, Bothwell TH, Torrance JD, et al. (1981) Factors affecting the absorption of iron from Fe(III) EDTA. Br J Nutr 45, 215-227.
46. Cercamondi CI, Egli IM, Ahouandjinou E, et al. (2010) Afebrile Plasmodium falciparum parasitemia decreases absorption of fortification iron but does not affect systemic iron utilization a double stable-isotope study in young Beninese women. Am J Clin Nutr 92, 1385-1392.
47. Rossander-Hulthén L & Hallberg L (1996) Dietary factors influencing iron absorption-an overview. In Iron Nutrition in Health and Disease [L Hallberg, editor]. London: John Libbey & Company.
48. Perron NR & Brumaghim JL (2009) A review of the antioxidant mechanisms of polyphenol compounds related to iron binding. Cell Biochem Biophys 53, 75-100.
49. Siegenberg D, Baynes RD, Bothwell TH, et al. (1991) Ascorbic-acid prevents the dose-dependent inhibitory effects of polyphenols and phytates on nonheme-iron absorption. Am J Clin Nutr 53, 537-541.
50. Matuschek E, Towo E & Svanberg U (2001) Oxidation of polyphenols in phytate-reduced high-tannin cereals: effect on different phenolic groups and on in vitro accessible iron. J Agric Food Chem 49, 5630-5638.
51. Aniszewski T, Lieberei R & Gulewicz K (2008) Research on catecholases, laccases and cresolases in plants. Recent progress and future needs. Acta Biol Cracov Bot 50, 7-18.
52. Stangoulis J, Sison C (2008) Crop sampling protocols for micronutrient analysis. HarvestPlus Technical Monograph Series. http://www.ifpri.org/sites/ default/files/publications/tech07.pdf (accessed January 2013).