28S rRNA is inducibly pseudouridylated by the mTOR pathway translational control in CHO cell cultures

Journal of Biotechnology

Volumn 174, Issue 1, 2014, Pages 16-21

  Courtes, Franck C ^a,b   Gu, Chen ^c   Wong, Niki S C ^a,d   Dedon, Peter C ^c   Yap, Miranda G S ^a,b   Lee, Dong Yup ^a,b  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d ABBVIE INC   (United States)

Author keywords

CHO cells culture; Inducible pseudouridylation; MTOR pathway; SnoRNA U19; Translatome

Indexed keywords

ANTIBIOTICS; CELL CULTURE; CELL ENGINEERING; CELLS; EFFICIENCY; RNA;

CHO CELL; MTOR PATHWAY; PSEUDOURIDYLATION; SNORNA U19; TRANSLATOME;

TRANSLATION (LANGUAGES);

MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; RAPAMYCIN; RIBOSOME RNA; RNA 28S; SMALL NUCLEOLAR RNA;

ARTICLE; BIOGENESIS; CELL ENGINEERING; CELL GROWTH; CHO CELL; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; POLYSOME; PRIORITY JOURNAL; RIBOSOME; SIGNAL TRANSDUCTION;

CHO CELLS CULTURE; INDUCIBLE PSEUDOURIDYLATION; MTOR PATHWAY; SNORNA U19; TRANSLATOME;

ANIMALS; BASE SEQUENCE; CHO CELLS; CRICETULUS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; PSEUDOURIDINE; RIBOSOMES; RNA, RIBOSOMAL, 28S; RNA, SMALL NUCLEOLAR; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84893684258     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.01.024     Document Type: Article

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