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Volumn 17, Issue 1, 2014, Pages 97-105

Maternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memory

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EID: 84893683097     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3596     Document Type: Article
Times cited : (50)

References (60)
  • 1
    • 0029989339 scopus 로고    scopus 로고
    • Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
    • Pasparakis, M., Alexopoulou, L., Episkopou, V. & Kollias, G. Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184, 1397-1411 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 1397-1411
    • Pasparakis, M.1    Alexopoulou, L.2    Episkopou, V.3    Kollias, G.4
  • 2
    • 21044457064 scopus 로고    scopus 로고
    • Novel tumor necrosis factor-knockout mice that lack Peyer's patches
    • Kuprash, D.V. et al. Novel tumor necrosis factor-knockout mice that lack Peyer's patches. Eur. J. Immunol. 35, 1592-1600 (2005).
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1592-1600
    • Kuprash, D.V.1
  • 3
    • 0031950741 scopus 로고    scopus 로고
    • Psychoneuroimmunology and the cytokine action in the CNS: Implications for psychiatric disorders. Prog. Neuropsychopharmacol
    • Müller, N. & Ackenheil, M. Psychoneuroimmunology and the cytokine action in the CNS: implications for psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 22, 1-33 (1998).
    • (1998) Biol. Psychiatry , vol.22 , pp. 1-33
    • Müller, N.1    Ackenheil, M.2
  • 4
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-alpha
    • Stellwagen, D. & Malenka, R.C. Synaptic scaling mediated by glial TNF-alpha. Nature 440, 1054-1059 (2006).
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 5
    • 0346992335 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor alpha in hippocampal development and function
    • Golan, H., Levav, T., Mendelsohn, A. & Huleihel, M. Involvement of tumor necrosis factor alpha in hippocampal development and function. Cereb. Cortex 14, 97-105 (2004).
    • (2004) Cereb. Cortex , vol.14 , pp. 97-105
    • Golan, H.1    Levav, T.2    Mendelsohn, A.3    Huleihel, M.4
  • 6
    • 0034333060 scopus 로고    scopus 로고
    • Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: Implications for emotional behavior
    • Yamada, K. et al. Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior. J. Neuroimmunol. 111, 131-138 (2000).
    • (2000) J. Neuroimmunol. , vol.111 , pp. 131-138
    • Yamada, K.1
  • 7
    • 77952161419 scopus 로고    scopus 로고
    • The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety
    • Gleason, G. et al. The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety. Proc. Natl. Acad. Sci. USA 107, 7592-7597 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7592-7597
    • Gleason, G.1
  • 8
    • 37349016848 scopus 로고    scopus 로고
    • Synaptic plasticity, memory and the hippocampus: A neural network approach to causality
    • Neves, G., Cooke, S.F. & Bliss, T.V. Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. Nat. Rev. Neurosci. 9, 65-75 (2008).
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 65-75
    • Neves, G.1    Cooke, S.F.2    Bliss, T.V.3
  • 9
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71 (1999).
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 10
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • van Praag, H., Kempermann, G. & Gage, F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 2, 266-270 (1999).
    • (1999) Nat. Neurosci. , vol.2 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 12
    • 33751235837 scopus 로고    scopus 로고
    • The role of acetylcholine in learning and memory
    • Hasselmo, M.E. The role of acetylcholine in learning and memory. Curr. Opin. Neurobiol. 16, 710-715 (2006).
    • (2006) Curr. Opin. Neurobiol. , vol.16 , pp. 710-715
    • Hasselmo, M.E.1
  • 13
    • 0036325126 scopus 로고    scopus 로고
    • Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography
    • Perry, D.C. et al. Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography. J. Neurochem. 82, 468-481 (2002).
    • (2002) J. Neurochem. , vol.82 , pp. 468-481
    • Perry, D.C.1
  • 14
    • 84870015777 scopus 로고    scopus 로고
    • Role of alpha-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus
    • Winner, B. et al. Role of alpha-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. J. Neurosci. 32, 16906-16916 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 16906-16916
    • Winner, B.1
  • 15
    • 33748883817 scopus 로고    scopus 로고
    • Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb
    • Kaneko, N., Okano, H. & Sawamoto, K. Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes Cells 11, 1145-1159 (2006).
    • (2006) Genes Cells , vol.11 , pp. 1145-1159
    • Kaneko, N.1    Okano, H.2    Sawamoto, K.3
  • 16
    • 1342321781 scopus 로고    scopus 로고
    • Interneuron diversity series: Interneuronal neuropeptides-endogenous regulators of neuronal excitability
    • Baraban, S.C. & Tallent, M.K. Interneuron diversity series: Interneuronal neuropeptides-endogenous regulators of neuronal excitability. Trends Neurosci. 27, 135-142 (2004).
    • (2004) Trends Neurosci. , vol.27 , pp. 135-142
    • Baraban, S.C.1    Tallent, M.K.2
  • 17
    • 0018097002 scopus 로고
    • Environmental complexity modulates growth of granule cell dendrites in developing but not adult hippocampus of rats
    • Fiala, B.A., Joyce, J.N. & Greenough, W.T. Environmental complexity modulates growth of granule cell dendrites in developing but not adult hippocampus of rats. Exp. Neurol. 59, 372-383 (1978).
    • (1978) Exp. Neurol. , vol.59 , pp. 372-383
    • Fiala, B.A.1    Joyce, J.N.2    Greenough, W.T.3
  • 18
    • 0033005713 scopus 로고    scopus 로고
    • Maternal care and the development of stress responses
    • Francis, D.D. & Meaney, M.J. Maternal care and the development of stress responses. Curr. Opin. Neurobiol. 9, 128-134 (1999).
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 128-134
    • Francis, D.D.1    Meaney, M.J.2
  • 19
    • 0027361432 scopus 로고
    • Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
    • Knight, D.M. et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol. Immunol. 30, 1443-1453 (1993).
    • (1993) Mol. Immunol. , vol.30 , pp. 1443-1453
    • Knight, D.M.1
  • 20
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler, K.M. et al. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J. Immunol. 151, 1548-1561 (1993).
    • (1993) J. Immunol. , vol.151 , pp. 1548-1561
    • Mohler, K.M.1
  • 21
    • 34548657310 scopus 로고    scopus 로고
    • Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection
    • Zalevsky, J. et al. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection. J. Immunol. 179, 1872-1883 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 1872-1883
    • Zalevsky, J.1
  • 22
    • 30744440898 scopus 로고    scopus 로고
    • Favorable response to subcutaneous administration of infliximab in rats with experimental colitis
    • Triantafillidis, J.K. et al. Favorable response to subcutaneous administration of infliximab in rats with experimental colitis. World J. Gastroenterol. 11, 6843-6847 (2005).
    • (2005) World J. Gastroenterol. , vol.11 , pp. 6843-6847
    • Triantafillidis, J.K.1
  • 23
    • 21244438311 scopus 로고    scopus 로고
    • Silencing TNFalpha activity by using Remicade or Enbrel blocks inflammation in whole muscle grafts: An in vivo bioassay to assess the efficacy of anti-cytokine drugs in mice
    • Grounds, M.D. et al. Silencing TNFalpha activity by using Remicade or Enbrel blocks inflammation in whole muscle grafts: an in vivo bioassay to assess the efficacy of anti-cytokine drugs in mice. Cell Tissue Res. 320, 509-515 (2005).
    • (2005) Cell Tissue Res. , vol.320 , pp. 509-515
    • Grounds, M.D.1
  • 24
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • Garrett, W.S. et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 8, 292-300 (2010).
    • (2010) Cell Host Microbe , vol.8 , pp. 292-300
    • Garrett, W.S.1
  • 25
    • 0032194952 scopus 로고    scopus 로고
    • P48/STAT-1alpha-containing complexes play a predominant role in induction of IFN-gamma-inducible protein, 10 kDa (IP-10) by IFN-gamma alone or in synergy with TNF-alpha
    • Majumder, S. et al. p48/STAT-1alpha-containing complexes play a predominant role in induction of IFN-gamma-inducible protein, 10 kDa (IP-10) by IFN-gamma alone or in synergy with TNF-alpha. J. Immunol. 161, 4736-4744 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 4736-4744
    • Majumder, S.1
  • 26
    • 0034710787 scopus 로고    scopus 로고
    • TNF-alpha stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells
    • Murao, K. et al. TNF-alpha stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells. Biochem. Biophys. Res. Commun. 276, 791-796 (2000).
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 791-796
    • Murao, K.1
  • 27
    • 33646089912 scopus 로고    scopus 로고
    • Killing the messenger in the nick of time: Persistence of breast milk sCD14 in the neonatal gastrointestinal tract
    • Blais, D.R., Harrold, J. & Altosaar, I. Killing the messenger in the nick of time: persistence of breast milk sCD14 in the neonatal gastrointestinal tract. Pediatr. Res. 59, 371-376 (2006).
    • (2006) Pediatr. Res. , vol.59 , pp. 371-376
    • Blais, D.R.1    Harrold, J.2    Altosaar, I.3
  • 28
    • 0348141712 scopus 로고    scopus 로고
    • Chemokines promote quiescence and survival of human neural progenitor cells
    • Krathwohl, M.D. & Kaiser, J.L. Chemokines promote quiescence and survival of human neural progenitor cells. Stem Cells 22, 109-118 (2004).
    • (2004) Stem Cells , vol.22 , pp. 109-118
    • Krathwohl, M.D.1    Kaiser, J.L.2
  • 29
    • 80052410357 scopus 로고    scopus 로고
    • The ageing systemic milieu negatively regulates neurogenesis and cognitive function
    • Villeda, S.A. et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90-94 (2011).
    • (2011) Nature , vol.477 , pp. 90-94
    • Villeda, S.A.1
  • 30
    • 0842324615 scopus 로고    scopus 로고
    • Chemokines: Multiple levels of leukocyte migration control
    • Moser, B., Wolf, M., Walz, A. & Loetscher, P. Chemokines: multiple levels of leukocyte migration control. Trends Immunol. 25, 75-84 (2004).
    • (2004) Trends Immunol. , vol.25 , pp. 75-84
    • Moser, B.1    Wolf, M.2    Walz, A.3    Loetscher, P.4
  • 31
    • 0035260758 scopus 로고    scopus 로고
    • Chemokines as regulators of T cell differentiation
    • Luther, S.A. & Cyster, J.G. Chemokines as regulators of T cell differentiation. Nat. Immunol. 2, 102-107 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 102-107
    • Luther, S.A.1    Cyster, J.G.2
  • 33
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann, G., Kuhn, H.G. & Gage, F.H. More hippocampal neurons in adult mice living in an enriched environment. Nature 386, 493-495 (1997).
    • (1997) Nature , vol.386 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 34
    • 20544463134 scopus 로고    scopus 로고
    • Regulation of dendritic development by neuronal activity
    • Chen, Y. & Ghosh, A. Regulation of dendritic development by neuronal activity. J. Neurobiol. 64, 4-10 (2005).
    • (2005) J. Neurobiol. , vol.64 , pp. 4-10
    • Chen, Y.1    Ghosh, A.2
  • 36
    • 2542596271 scopus 로고    scopus 로고
    • T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions
    • Kipnis, J., Cohen, H., Cardon, M., Ziv, Y. & Schwartz, M. T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions. Proc. Natl. Acad. Sci. USA 101, 8180-8185 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8180-8185
    • Kipnis, J.1    Cohen, H.2    Cardon, M.3    Ziv, Y.4    Schwartz, M.5
  • 37
    • 77954726290 scopus 로고    scopus 로고
    • Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-alpha in normal pregnancies and in pregnancies complicated by preeclampsia
    • Tosun, M. et al. Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-alpha in normal pregnancies and in pregnancies complicated by preeclampsia. J. Matern. Fetal Neonatal Med. 23, 880-886 (2010).
    • (2010) J. Matern. Fetal Neonatal Med. , vol.23 , pp. 880-886
    • Tosun, M.1
  • 38
    • 0035679810 scopus 로고    scopus 로고
    • Maternal cytokine levels during pregnancy and adult psychosis
    • Buka, S.L. et al. Maternal cytokine levels during pregnancy and adult psychosis. Brain Behav. Immun. 15, 411-420 (2001).
    • (2001) Brain Behav. Immun. , vol.15 , pp. 411-420
    • Buka, S.L.1
  • 39
    • 0030854812 scopus 로고    scopus 로고
    • Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha (TNF alpha) production in humans: High sensitivity of TNF alpha and resistance of IL-6
    • DeRijk, R. et al. Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha (TNF alpha) production in humans: high sensitivity of TNF alpha and resistance of IL-6. J. Clin. Endocrinol. Metab. 82, 2182-2191 (1997).
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2182-2191
    • Derijk, R.1
  • 40
    • 0034082524 scopus 로고    scopus 로고
    • The stress response and the hypothalamic-pituitary-adrenal axis: From molecule to melancholia
    • O'Connor, T.M., O'Halloran, D.J. & Shanahan, F. The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia. QJM 93, 323-333 (2000).
    • (2000) QJM , vol.93 , pp. 323-333
    • O'Connor, T.M.1    O'Halloran, D.J.2    Shanahan, F.3
  • 41
    • 0023747151 scopus 로고
    • Effect of the exercise-induced increase in glucocorticoids on endurance in the rat
    • Sellers, T.L., Jaussi, A.W., Yang, H.T., Heninger, R.W. & Winder, W.W. Effect of the exercise-induced increase in glucocorticoids on endurance in the rat. J. Appl. Physiol. 65, 173-178 (1988).
    • (1988) J. Appl. Physiol. , vol.65 , pp. 173-178
    • Sellers, T.L.1    Jaussi, A.W.2    Yang, H.T.3    Heninger, R.W.4    Winder, W.W.5
  • 42
    • 0034674653 scopus 로고    scopus 로고
    • Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter
    • Steer, J.H., Kroeger, K.M., Abraham, L.J. & Joyce, D.A. Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter. J. Biol. Chem. 275, 18432-18440 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 18432-18440
    • Steer, J.H.1    Kroeger, K.M.2    Abraham, L.J.3    Joyce, D.A.4
  • 43
    • 54949149516 scopus 로고    scopus 로고
    • Disease activity of rheumatoid arthritis during pregnancy: Results from a nationwide prospective study
    • de Man, Y.A., Dolhain, R.J., van de Geijn, F.E., Willemsen, S.P. & Hazes, J.M. Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum. 59, 1241-1248 (2008).
    • (2008) Arthritis Rheum , vol.59 , pp. 1241-1248
    • De Man, Y.A.1    Dolhain, R.J.2    Van De Geijn, F.E.3    Willemsen, S.P.4    Hazes, J.M.5
  • 44
    • 33646548627 scopus 로고    scopus 로고
    • A new chapter opens in anti-inflammatory treatments: The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice
    • Brustolim, D., Ribeiro-dos-Santos, R., Kast, R.E., Altschuler, E.L. & Soares, M.B. A new chapter opens in anti-inflammatory treatments: the antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice. Int. Immunopharmacol. 6, 903-907 (2006).
    • (2006) Int. Immunopharmacol. , vol.6 , pp. 903-907
    • Brustolim, D.1    Ribeiro-Dos-Santos, R.2    Kast, R.E.3    Altschuler, E.L.4    Soares, M.B.5
  • 45
    • 54349110896 scopus 로고    scopus 로고
    • Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-alpha-induced inflammation with extraordinary potency
    • Yu, B. et al. Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-alpha-induced inflammation with extraordinary potency. J. Pharmacol. Exp. Ther. 327, 316-323 (2008).
    • (2008) J. Pharmacol. Exp. Ther. , vol.327 , pp. 316-323
    • Yu, B.1
  • 46
    • 53149153876 scopus 로고    scopus 로고
    • The adaptive value of stress-induced phenotypes: Effects of maternally derived corticosterone on sex-biased investment, cost of reproduction, and maternal fitness
    • Love, O.P. & Williams, T.D. The adaptive value of stress-induced phenotypes: effects of maternally derived corticosterone on sex-biased investment, cost of reproduction, and maternal fitness. Am. Nat. 172, E135-E149 (2008).
    • (2008) Am. Nat. , vol.172
    • Love, O.P.1    Williams, T.D.2
  • 47
    • 79952705355 scopus 로고    scopus 로고
    • Prenatal stress and the programming of disease
    • Harris, A. & Seckl, J. Glucocorticoids, prenatal stress and the programming of disease. Horm. Behav. 59, 279-289 (2011).
    • (2011) Horm. Behav. , vol.59 , pp. 279-289
    • Harris, A.1    Glucocorticoids, S.J.2
  • 48
    • 33644857007 scopus 로고    scopus 로고
    • Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring
    • Bick-Sander, A., Steiner, B., Wolf, S.A., Babu, H. & Kempermann, G. Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring. Proc. Natl. Acad. Sci. USA 103, 3852-3857 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 3852-3857
    • Bick-Sander, A.1    Steiner, B.2    Wolf, S.A.3    Babu, H.4    Kempermann, G.5
  • 49
    • 0027249702 scopus 로고
    • Progeny of mothers drinking corticosterone during lactation has lower stress-induced corticosterone secretion and better cognitive performance
    • Catalani, A. et al. Progeny of mothers drinking corticosterone during lactation has lower stress-induced corticosterone secretion and better cognitive performance. Brain Res. 624, 209-215 (1993).
    • (1993) Brain Res. , vol.624 , pp. 209-215
    • Catalani, A.1
  • 50
    • 74549183435 scopus 로고    scopus 로고
    • Cytokines in human milk
    • Garofalo, R. Cytokines in human milk. J. Pediatr. 156, S36-S40 (2010).
    • (2010) J. Pediatr. , vol.156
    • Garofalo, R.1
  • 51
    • 0032842478 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
    • Tronche, F. et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat. Genet. 23, 99-103 (1999).
    • (1999) Nat. Genet. , vol.23 , pp. 99-103
    • Tronche, F.1
  • 52
  • 53
    • 19944432071 scopus 로고    scopus 로고
    • Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: Protective and deleterious effects
    • Grivennikov, S.I. et al. Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects. Immunity 22, 93-104 (2005).
    • (2005) Immunity , vol.22 , pp. 93-104
    • Grivennikov, S.I.1
  • 54
    • 33751213392 scopus 로고    scopus 로고
    • Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
    • Saxe, M.D. et al. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc. Natl. Acad. Sci. USA 103, 17501-17506 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17501-17506
    • Saxe, M.D.1
  • 56
    • 46249127576 scopus 로고    scopus 로고
    • Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus
    • Tatapudy, S., Bruening, S., Gleason, G. & Toth, M. Validation and use of a computer-assisted counting procedure to quantify BrdU-labeled proliferating cells in the early postnatal mouse hippocampus. J. Neurosci. Methods 172, 173-177 (2008).
    • (2008) J. Neurosci. Methods , vol.172 , pp. 173-177
    • Tatapudy, S.1    Bruening, S.2    Gleason, G.3    Toth, M.4
  • 57
    • 3242703144 scopus 로고    scopus 로고
    • Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: Evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors
    • Bailey, S.J. & Toth, M. Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors. J. Neurosci. 24, 6343-6351 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 6343-6351
    • Bailey, S.J.1    Toth, M.2
  • 58
    • 68849110235 scopus 로고    scopus 로고
    • Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
    • Dumont, M. et al. Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease. FASEB J. 23, 2459-2466 (2009).
    • (2009) FASEB J. , vol.23 , pp. 2459-2466
    • Dumont, M.1
  • 59
    • 79551624514 scopus 로고    scopus 로고
    • Selective early-acquired fear memories undergo temporary suppression during adolescence
    • Pattwell, S.S., Bath, K.G., Casey, B.J., Ninan, I. & Lee, F.S. Selective early-acquired fear memories undergo temporary suppression during adolescence. Proc. Natl. Acad. Sci. USA 108, 1182-1187 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 1182-1187
    • Pattwell, S.S.1    Bath, K.G.2    Casey, B.J.3    Ninan, I.4    Lee, F.S.5
  • 60
    • 78349261176 scopus 로고    scopus 로고
    • Role of maternal 5-HT(1A) receptor in programming offspring emotional and physical development
    • van Velzen, A. & Toth, M. Role of maternal 5-HT(1A) receptor in programming offspring emotional and physical development. Genes Brain Behav. 9, 877-885 (2010).
    • (2010) Genes Brain Behav. , vol.9 , pp. 877-885
    • Van Velzen, A.1    Toth, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.